Patents Examined by Kathleen McCowin
  • Patent number: 4425430
    Abstract: A process for producing an antibiotic, which comprises cultivating an antibiotic KA-6606-producing strain of an genus Saccharopolyspora in a nutrient culture medium, isolating the antibiotic KA-6606-containing substance from the culture broth, and separating from the resulting antibiotic KA-6606-containing substance at least one antibiotic selected from the group consisting of antibiotic KA-6606 VII, KA-6606 VIII, KA-6606 IX, KIA-6606 X, KA-6606 XI, KA-6606 XII, KA-6606 XIII, KA-6606 XIV, KA-6606 XV, KIA-6606 XVI and KA-6606 XVII; and novel antibiotics KA-6606 XII, XIII and XV to XVII.
    Type: Grant
    Filed: July 9, 1981
    Date of Patent: January 10, 1984
    Assignee: Kowa Company, Ltd.
    Inventors: Akio Iwasaki, Takeo Deushi, Isamu Watanabe, Toshihito Mori
  • Patent number: 4349630
    Abstract: A heat-resistant water soluble derivative of urokinase is prepared which comprises urokinase covalently bonded to a copolymer of acrylamide and acrylic acid having a molecular weight of 10,000 to 200,000 and a content of acrylic acid of 1% to 2%. The derivative contains 15% to 35% urokinase and has an esterase and amidolytic activity of from 10% to 80%.
    Type: Grant
    Filed: August 27, 1980
    Date of Patent: September 14, 1982
    Inventors: Alexandr V. Maximenko, Vladimir P. Torchilin, Vladimir N. Smirnov, Evgeny I. Chazov