Patents Examined by Konata M. George
  • Patent number: 7488495
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
    Type: Grant
    Filed: October 13, 2004
    Date of Patent: February 10, 2009
    Assignee: Relypsa, Inc.
    Inventors: Dominique Charmot, Han Ting Chang, Gerrit Klaerner, Michael James Cope, Mingjun Liu, Futian Liu, Jerry Buysse, Eric Connor, Tony Kwok-Kong Mong, Jun Shao, Deidre Madsen
  • Patent number: 7470433
    Abstract: The present invention relates generally to formulations for transdermal or transmucosal administration of an active agent such as estradiol. The invention is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of long chain fatty alcohols, long-chain fatty acids, and long-chain fatty esters.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: December 30, 2008
    Assignee: Antares Pharma IPL AG
    Inventors: Dario Norberto R. Carrara, Arnaud Grenier, Celine Besse, Stephen M. Simes, Leah M. Lehman
  • Patent number: 7470436
    Abstract: A water-soluble composition comprising (A) coenzyme Q10 of 5-40% by weight, (B) monoester of polyglycerol with average polymerization degree of 10 and fatty acid with 18 carbon atoms of 5-30% by weight, (C) mono-, di-, tri- or penta-ester of polyglycerol with average polymerization degree of 3-6 and fatty acid with 18 carbon atoms of 1-18% by weight, and (D) water, wherein its average particle diameter is 110 nm or smaller. It is superior in acid resistance, salt-resistance and heat resistance, and further enables to maintain the good water-soluble state being blended to medicines, foods and beverages, cosmetics, feeds, additives usually employed therein.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: December 30, 2008
    Assignee: Nisshin Pharma Inc.
    Inventors: Takeshi Segawa, Atsuko Abe, Tsuyoshi Minemura, Hironori Kubota
  • Patent number: 7468195
    Abstract: A skin treatment preparation including carriers, a medicinal vector encapsulating a plant extract (Cucumis melo protein extract) rich in reductase, catalase and superoxide dismutase is characterized in that the medicinal vector, of nanospheres, represents 1 to 20 wt. % of the weight of the preparation; and the encapsulated plant extract represents 5 to 15 wt. % of the weight of the nanospheres; and the encapsulated plant extract may have the following enzymatic concentrations: reductase between 100 and 1000 IU, catalase between 100 and 1000 IU, and superoxide dismutase between 500 and 5000 IU. The preparation is useful for limiting depigmentation and reducing inflammatory front in vilitigo pathology and possible repigmentation.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: December 23, 2008
    Assignee: Crawford Healthcare Limited
    Inventor: Christian Diehl
  • Patent number: 7462363
    Abstract: Composition including an oil phase, an aqueous phase, at least one emulsifying system of water-in-oil (W/O) type, optionally at least one emulsifying system of oil-in-water (O/W) type, in the form of an inverse latex including from 20% to 70% by mass and preferably from 25% to 50% by mass of a branched or crosslinked polyelectrolyte, characterized in that the polyelectrolyte is a copolymer of 2-acrylamido-2-methylpropanesulfonic acid partially or totally salified with N,N-dimethylacrylamide and optionally one or more monomers chosen from monomers containing a partially or totally salified weak acid function and neutral monomers. Cosmetic use.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: December 9, 2008
    Assignee: Societe d'Exploitation de Produits pour les Industries Chimiques Seppic
    Inventors: Olivier Braun, Paul Mallo, Stephanie Basset
  • Patent number: 7462367
    Abstract: An inhalable powder comprising: (a) an active substance consisting essentially of a compound of formula 1 ?wherein X? is a pharmaceutically acceptable anion; and (b) a physiologically acceptable excipient having an average particle size of 10 ?m to 50 ?m, processes for preparing the inhalable powder, and methods of administration for the treatment of respiratory complaints, particularly for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: December 9, 2008
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Friedrich Schmidt, Michael Trunk
  • Patent number: 7455858
    Abstract: The invention provides nanoparticles containing photosensitizers and their use in the field of photodynamic therapy (PDT). The invention also provides methods for the preparation of such nanoparticles as well as for their sterilization.
    Type: Grant
    Filed: May 15, 2003
    Date of Patent: November 25, 2008
    Assignee: QLT Inc.
    Inventors: Eric Allemann, Yvette Konan, Robert Gurny, Ronald E. Boch
  • Patent number: 7455849
    Abstract: The present invention is an aqueous, non-alcoholic liquid powder formulation. The aqueous, non-alcoholic liquid powder formulation comprises from about 14% to about 75% by weight of the formulation of water, from about 25% to about 60% by weight of the formulation of a powder, from about 0.05% to about 1% by weight of the formulation of a polymeric emulsifier, from about 0.5% to about 15% by weight of the formulation of a low molecular weight silicone wherein the low molecular weight silicone has an average molecular weight of about 10,000 or less, and from about 0.1% to about 10% by weight of the formulation of a high molecular weight silicone wherein the high molecular weight silicone has an average molecular weight of about 100,000 or greater. The aqueous, non-alcoholic liquid powder formulation may have an optical uniformity index of about 0.1 or less. The aqueous, non-alcoholic liquid powder formulation may have an extensive uniformity index of about 300 or greater.
    Type: Grant
    Filed: September 16, 2004
    Date of Patent: November 25, 2008
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Julie Marie Utschig, Keisha Lori Clarke, Wael Rafat Joseph, David William Koenig, Duane Gerard Krzysik
  • Patent number: 7455831
    Abstract: Disclosed herein is a nail varnish composition comprising, in a cosmetically acceptable medium, at least one film-forming polymer, wherein the varnish composition is capable of forming a film having a rate of mass loss of less than 0.5 mg/minute when the film is subjected to abrasion produced with the Taber abrasimeter at 23° C., as well as a method for making up and/or non-therapeutic care of the nails comprising applying to the nails the composition.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: November 25, 2008
    Assignee: L'Oreal S.A.
    Inventors: Marco Vicic, Colette Cazeneuve, Nathalie Mougin
  • Patent number: 7449199
    Abstract: The present invention relates to a nanostructural substance constituted from primary particles having a particle diameter of not more than 30 nm. In the nanostructural substance of the present invention, the primary particles have a small particle diameter, and a contact surface between the primary particles is small. In particular, since the nanostructural substance of the present invention has a large content of molecules existing at the surface thereof and, therefore, a high surface energy as compared to simple agglomerated particles, it is expected to more remarkably exhibit functions of the compound constituting the primary particles. In addition, titanium oxide particles constituted from the nanostructural substance comprising primary particles having a small particle diameter and a small contact area therebetween according to the present invention exhibit a high catalytic activity and can be suitably used, in particular, as a photocatalyst.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: November 11, 2008
    Assignee: Toda Kogyo Corporation
    Inventors: Tomohiro Honda, Tomoaki Urai, Katsuaki Kurata
  • Patent number: 7449613
    Abstract: The present invention relates to a film-forming barrier composition useful for protecting the skin from body fluids, such as urine, feces, menses. The composition comprises a skin conditioning agent, a viscosity enhancing agent and an oleophilic film-forming agent. Optionally, the lotion may comprise skin care ingredients for treating or maintaining skin health. The composition may be applied to the skin by suitable delivery vehicles, such as absorbent articles or components thereof, sheet materials, pads, bandages, sponges, foam pads, pumps, sprays, depending on the viscosity of the composition.
    Type: Grant
    Filed: November 14, 2005
    Date of Patent: November 11, 2008
    Assignee: The Procter & Gamble Company
    Inventors: Thomas James Klofta, James Anthony Staudigel, George Endel Deckner
  • Patent number: 7445797
    Abstract: A boron nitride composition having its surface treated with a coating layer comprising a zirconate coupling agent. The boron nitride composition can be used as fillers in polymeric compounds at levels of up to 90 wt. %, giving thermal conductivity of up to 35 W/mK.
    Type: Grant
    Filed: October 12, 2005
    Date of Patent: November 4, 2008
    Assignee: Momentive Performance Materials Inc.
    Inventors: Paulo Meneghetti, Paul Joseph Hans, Gregory W. Shaffer
  • Patent number: 7445790
    Abstract: The present invention is a skin treatment composition that characteristically contains an alkyl benzoate represented by the following general formula (1). This provides a skin treatment composition that gives a refreshing sensation at the time of application and can contain drugs and ultraviolet absorbents in a stable manner. Also, the present invention is a sunblock water-in-oil type emulsified cosmetic characteristically comprising an ester bond product of polyhydroxystearic acid represented by the following general formulas (2) or (3), alkyl benzoate represented by the following general formula (1), and an ultraviolet absorbent. This provides a sunblock cosmetic consisting of a water-in-oil type emulsified composition that can contain an ultraviolet absorbent in a stable manner and exhibits a superior usability. (In this formula, R denotes a branched or straight chain alkyl group having 8-15 carbon atoms.
    Type: Grant
    Filed: May 7, 2003
    Date of Patent: November 4, 2008
    Assignee: Shiseido Company, Ltd.
    Inventors: Nozomi Oguchi, Reiji Miyahara, Hiroyuki Kakoki, Takayuki Omura
  • Patent number: 7445795
    Abstract: An active principle delivery device (1) comprising an inner capsule (4) within an outer capsule (2), the inner and outer capsules (4,2) containing the same active principle (5,3), with at least the outer capsule (2) being a hard capsule and the active principle (3,5) in at least one of the capsules (2,4), comprising a fluid. Also provided is a method of fabricating such a delivery device (1), as well as a method of controlling the pharmaco-kinetic profile of an active principle.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: November 4, 2008
    Assignee: MW Encap Limited
    Inventors: Massoud Bakhshaee, William John Bowtle, Alyn Brandon McNaughton
  • Patent number: 7439270
    Abstract: Spinal anesthetics for intrathecal administration to produce spinal anesthesia are provided with use of 6-[2-(1(2)H-tetrazole-5-yl)ethyl]decahydroisoquinolone-3-carboxylic acid or its pharmaceutically active analogues.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: October 21, 2008
    Assignee: Univeristy of Iowa Research Foundation
    Inventor: Timothy J. Brennan
  • Patent number: 7438203
    Abstract: The invention relates to a method for treatment or prophylaxis of a disease or condition in an animal comprising administering to a mucosal membrane of said animal in need of such treatment a therapeutically effective amount of a drug delivery system comprising at least one physiologically active agent or prodrug thereof and at least one penetration enhancer selected from safe ester sunscreens.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: October 21, 2008
    Assignee: Acrux DDS Pty Ltd
    Inventors: Barry Lenard Reed, Timothy Matthias Morgan, Barrie Charles Finnin
  • Patent number: 7438896
    Abstract: Methods for the prevention of skin damage arising from exposure to ultraviolet or solar radiation, using lipoic acid and asorbic acid and/or ascorbic acid derivative in a dermatologically acceptable carrier that can be topically applied to the skin areas. Tocotrienol and/or an ?-hydroxy acid such as glycolic acid is applied with the lipoic acid and ascorbic acid an/or its derivatives in some embodiments.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: October 21, 2008
    Assignee: N.V. Perricone LLC
    Inventor: Nicholas V. Perricone
  • Patent number: 7431938
    Abstract: A texturizing composition and method utilized for foundations, makeup powders, mascaras, lipsticks, emulsions, lotions, gels, sprayable formulations, and solutions impregnated on fabrics, paper, towelettes or complexion corrector papers comprising at least one self-invertible inverse latex, and powder.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: October 7, 2008
    Assignee: Societe d'Exploitation de Produits pour les Industries Chimiques Seppic
    Inventors: Alicia Roso, Nelly Michel, Catherine Bulcourt
  • Patent number: 7429394
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: September 30, 2008
    Assignee: Relypsa, Inc.
    Inventors: Dominique Charmot, John Fordtran, Han Ting Chang, Eric Connor, Mingjun Liu, Gerrit Klaerner
  • Patent number: 7427412
    Abstract: The invention relates to cosmetic compositions comprising an elastic, non-rigid, porous support in which a low-viscosity, gellant-containing, single phase otherwise unstable cosmetic formulation has been incorporated, and a method of making same.
    Type: Grant
    Filed: June 21, 2000
    Date of Patent: September 23, 2008
    Assignee: Color Access, Inc.
    Inventors: Rachel J. Painter, Isaac David Cohen