Abstract: Methods herein disclosed include methods of producing a nanoporous membrane by coating a planar substrate (204) with a solution (solution tank 201) containing a reactive metal adatom. The coated planar substrate can then be perforated by initiating a redox reaction between the reactive metal adatom and the planar substrate that causes the reactive metal adatom to remove material, forming nanoscale pores in the planar substrate that result in a nanoporous planar material. This nanoporous planar material can be formed into a nanoporous membrane.

Abstract: Embodiments in accordance with the present invention encompass a composition comprising one or more of polycyclic olefinic monomers of formula (I) and one or more monomers of formula (III) for forming anion exchange membrane optionally in combination with one or more monomers of formula (II). The composition undergoes mass vinyl addition polymerization either under thermal or photolytic conditions and can be formed into ionomers on a suitable membrane support. The membrane supports thus formed are suitable as anion exchange membranes for fabricating a variety of electrochemical devices, among others. More specifically, the ionomeric membranes are formed on a variety of supports which contains a variety of quaternized amino functionalized norbornene monomeric units which are lightly crosslinked (less than five mol %). The membranes so formed exhibit very high ionic conductivity of up to 280 mS/cm at 80° C.

Abstract: In one or more embodiments, a liquid filter 100 to filter fuel or lubricant is provided. The liquid filter 100 includes a housing 102 extending along the vertical axis XX?. The housing 102 has a cylindrical shape and includes a top end cap 104 and a bottom end cap 106 provided at both ends. The top end cap 104 and the bottom end cap 106 are integratedly formed in one piece with the housing 102. The top end cap 104 includes an outlet 108 for allowing outflow of filtered liquid from the housing 102. A hand priming pump 110 is functionally attached to the outlet 108 of the top end cap 104 for easing priming. The bottom end cap 106 includes an inlet 112 for allowing inflow of dirty liquid inside the housing 102.

Abstract: An apparatus for separating mixed together substances of different flowability has a frame structure and a hollow drum with a perforated circumferential surface driven in a revolving manner and mounted on the frame structure. A pressing element lies externally in the region of the circumferential surface of the drum and is driven in a revolving manner, such that the drum and the pressing element form a product intake wedge for the feeding in a product stream, of material to be pressed. The drum and pressing element also form a pressing region. A discharge element is associated with the pressing element downstream of the pressing region in the product stream conveying direction, for discharging residues that remain on the pressing element after pressing. The discharge element is an actively drivable, endless discharge belt for discharging the residues in a discharge direction. A corresponding method is also provided.

Abstract: The present disclosure relates to multistep chromatographic methods for preparing extracellular vesicles (EVs). The methods were demonstrated to be effective in preparing highquality EVs in a large scale. The methods enable preparation of EVs for therapeutic and diagnostic applications, and isolation and/or sub-fractionation of EVs with desired properties for specific use.

Abstract: A centrifugal dehydrator according to an embodiment of the present disclosure for solving the above problems includes: a slurry flow tube through which slurry, in which polymers and water are mixed, flows; a gas flow tube through which a gas flows; a mixture flow tube which is connected from the slurry flow tube and the gas flow tube and through which a mixture of the slurry and the gas flows; a basket into which the mixture is injected from the mixture flow tube and which rotates to apply centrifugal force to the slurry in the mixture; a driving part that allows the basket to rotate; and a porous plate disposed on a peripheral portion of the basket to discharge the water from the slurry to the outside of the basket.

Abstract: [Object] A target cell capture filter is provided, having an improved capture ratio per unit area, structured as a filter for extracting and capturing target cells contained in a biological sample such as blood or the like in a simple manner, in a short period of time, and with high efficiency. [Solving Means] A target cell capture filter is structured to have a capture face for capturing target cells in a liquid. The target cell capture filter has multiple notches that allows a part of the capture face to be elastically deformed in a direction that is orthogonal to the capture face, thereby providing gaps. At least part of the plurality of notches are a first notch group including multiple notches designed such that there is a difference between the notches in a shortest distance from a greatest deformation location of the notch to an outer edge of the capture face, and such that the same elastic deformation amount is exhibited with respect to the impulse per unit area.

Abstract: A water purifier including a raw water flow path, a first valve provided in a water purification path, a second valve provided in a wash water flow path, a purified water valve provided in a purified water supply tube, a flow sensor provided in a cooking water supply tube and sensing a flow amount of liquid flowing in the cooking water supply tube, a drainage valve provided in a drainage flow path branched from the cooking water supply tube and a controller for draining the liquid remaining in the cooking water supply tube, when a flow amount value sensed by the flow sensor for a preset period of time is less than or equal to a certain value, by controlling opening/closing of the purified water valve, the first valve, the second valve, and the drainage valve.

Abstract: Nanoporous selective sol-gel ceramic membranes, selective-membrane structures, and related methods are described. Representative ceramic selective membranes include ion-conductive membranes (e.g., proton-conducting membranes) and gas selective membranes. Representative uses for the membranes include incorporation into fuel cells and redox flow batteries (RFB) as ion-conducting membranes.

Abstract: The present disclosure provides a grid system, including a grid body and supports, where the grid body includes a water intake module, a filtering module, a residue scraping module, a residue pressing module, and a water discharge module; the filtering module is disposed at a middle-upper part of the grid body, the water intake module and the residue pressing module are organically coupled at a lower part of the filtering module, and the water intake module includes a water inlet and a water distribution area; the filtering module includes a water retaining platform, an inflow water guide plate, screen plate areas, and a central water retaining weir; the residue scraping module includes scrapers, a driving motor, a support frame, a residue inlet, and a guide rail; the residue pressing module includes a squeezing cylinder, a motor, and a residue outlet.

Abstract: A fluid treatment device has an exchangeable treatment unit and a connection head. A bayonet-type connection device connects connection head and treatment unit to each other by a plug-in/rotation movement about a connection axis of the treatment device and is provided with a housing connection part and a head connection part that operatively engage each other to form a connection of the bayonet-type connection device. Housing connection part and head connection part each have a mutually complementary functional element extending circumferentially about the connection axis and operatively connectable to each other. The bayonet-type connection device has a pretension element for realizing a mechanical pretension pressing the functional elements against each other. A splash guard part is provided that covers at least the connection device.

Abstract: Systems, devices, and methods are provided for removing carbon dioxide from a target fluid, such as, for example, blood, to treat hypercarbic respiratory failure or another condition. A device is provided including first and second membrane components for removing dissolved gaseous carbon dioxide and bicarbonate from the fluid, which can be done simultaneously. The device can be in the form of a cartridge configured for use in a dialysis system. A method of treatment is also provided, involving drawing blood from a patient and bringing the patient's blood in contact with a first membrane component having a sweep gas passing therethrough, and a second membrane component having a dialysate passing therethrough. The dialysate's composition can be selected such that charge neutrality is maintained.

Abstract: A membrane distillation module comprising a membrane distillation cartridge and a membrane distillation housing, wherein: the cartridge comprises a anchoring part in which porous membranes are anchored by resin; the housing comprises a housing body and a housing lid; the membrane distillation module comprises a support part where the outer surface of the anchoring part is supported by the inner surface of the housing with a seal member interposed therebetween; and a value C in the cross section of the support part is at least 30° C. as represented by the formula, where dF is the equivalent circular diameter (mm) of the outer circumference of the anchoring part, kF is the linear expansion coefficient (1/° C.) of the resin, dE is the equivalent diameter (mm) of the inner circumference of the housing, and kE is the linear expansion coefficient (1/° C.) of a portion where the housing contacts the seal member.

Abstract: Biological filters for removing target components from biological fluids such as removal of pathogenic cells from whole blood, are described. The filters may include a medium comprising an inert surface, with capture material disposed on the inert surface. The filter may be configured to selectively recognize, capture, and remove target cells such as pathogenic cells associated with a disease, such as an autoimmune disease or cancer. Devices, systems, apparatuses, computer readable media, and methods associated with biological filtering are also provided.

Abstract: A hollow fiber membrane module (100) of the present invention includes: a plurality of hollow fiber membranes (10); a binding portion (20) binding the plurality of hollow fiber membranes (10) at one end portions thereof; and a cap (30) having an internal space (30s) that communicates with each of the plurality of hollow fiber membranes (10), the cap (30) being integrated with the binding portion (20); and a housing (40) that houses the plurality of hollow fiber membranes (10) and the binding portion (20), and that has one end portion to which the cap (30) is attached. A unit (70) including the plurality of hollow fiber membranes (10), the binding portion (20), and the cap (30) is detached from the housing (40) and the unit (70) is attached to the housing (40) while integration of the binding portion (20) and the cap (30) is maintained.

Abstract: A device for determining a dialysis efficiency/dialysis dose of an extracorporeal blood treatment process has a radiation source, a cuvette, a detection unit and a control unit. The radiation source emits radiation, the intensity of which is controlled by adjusting a current intensity applied to the radiation source. The cuvette is preferably provided with an inlet and outlet, and is penetrated by radiation emitted by the radiation source. The detection unit detects the intensity of the radiation after the radiation passes the cuvette. The control unit determines the dialysis efficiency/dialysis dose from the intensity detected by the detection unit. The control unit, which is connected to the radiation source and detection unit, reduces the intensity of the radiation by adjusting the current intensity during the extracorporeal blood treatment process at least once, based on a drop in concentration of substances excreted in the urine in the dialysis fluid.

Abstract: A method of synthesizing a mixed matrix membrane (MMM) film. The method includes: synthesizing a polymer including a polynorbornene or a polytricyclononene; synthesizing covalent-triazine frameworks (CTFs); preparing a polymer solution by dissolving the polymer in a first solvent; preparing a filler solution by dispersing the CTFs in a second solvent; adding the polymer solution to the filler solution while stirring the filler solution, forming a casting solution; pouring the casting solution into a membrane support; and drying the poured casting solution in the membrane support to form the MMM film including the CTFs.

Abstract: The present invention relates to a crossflow membrane module configured to separate a feed fluid into a permeate fluid and a residue fluid across one or more membrane sheet(s). The crossflow module comprises a second end offset from a first end along the first direction where an inlet is provided at the first end and an outlet is provided at the second end. The one or more membrane sheet(s) each have a first portion and a second portion. A conduit is adjacent to the first side of each membrane sheet and is configured to receive and output the permeate fluid separated from the feed fluid. The second portion of the membrane sheet has a greater permeance for a major component than the first portion such that the second part of the permeate fluid, which is generated by separation across the second portion of the membrane sheet, has a higher concentration of the major component than the first part of the permeate fluid, which is generated by separation across the first portion.

Abstract: Methods of producing multiple protein products from blood-based materials including alpha-1-proteinase inhibitor, gamma globulin, albumin, and other proteins are described herein. The inventive methods include steps of: salt fractionation, chromatography, ultrafiltration, diafiltration, solvent-detergent treatment, and sterile filtration. Advantageously, the inventive methods are simple and produce alpha-1-proteinase inhibitor, gamma globulin, albumin, and other proteins in high yields. The sequence of process steps can be selected to obtain multiple products from various in-process materials, such as supernatants, pastes, chromatography flow-though, and chromatography washes.

Abstract: A connector arrangement (10) for connecting to a fluid chamber (6) of a blood treatment unit (4) for extracorporeal blood treatments. The connector arrangement (10) includes a connector device (11) with a connector body (47) comprising a port opening (43) and an interior wall (50) defining a port space (39) designed to receive a first fluid port (8A) of the fluid chamber (6). The connector device (11) also incorporates a fluid path (35a) extending from the port space (39) to a first end opening (51) of the connector device (11), and an air path (36a) extending from the port space (39) to a second end opening (52) of the connector device (11), wherein the fluid path (35a) and the air path (36a) are separate paths. Also a system (1) for extracorporeal blood treatment including the connector arrangement (10) and a method for priming the fluid chamber (6).