Abstract: The present invention relates to an oral plaque dispersion agent capable of effectively acting on dental plaque from the surface layer to the deep part thereof and exerting an excellent effect of dispersing the dental plaque. Specifically, the present invention relates to an oral plaque dispersion agent comprising (A) a water-soluble compound 3 or more of primary hydroxyl groups in the molecular structure and 100 or more and 200 or less of a chemical formula weight as an active component.

Abstract: Some embodiments described herein provide for a multi-component compositions and methods for its pharmaceutical and cosmetic use, comprising a combination of an aliphatic anionic compound, an oxidative compound, and a buffering system. Source of fluoride ion and other carriers are optional ingredients. The aliphatic anionic compound and the oxidative compound function together, in presence or absence of fluoride ion source, to protect the oxidative compounds from degradation prior to use and upon use, and to enhance the efficacy of the composition. In addition to achieving greater stability, combined effects of the aliphatic anionic compound, oxidative compound and source of fluoride ion achieve enhanced fluoride uptake, higher enamel protection by enhanced remineralization and reduced demineralization, increased plaque removal, reduced re-growth of plaque polymicrobial biofilm, greater amount of chlorite ion availability and effective oxidation of salivary biomolecules.

Abstract: A smokeless tobacco product or medicinal nicotine product includes nicotine and camphor dissolved in a non-flavored oily carrier. Preferably, the camphor is present in a concentration ranging from about 600 ppm to about 1300 ppm. Also disclosed are methods of making such products.

Abstract: A method of treating diseased tissue while healing the wound using a diode laser which generates a beam of light having a wavelength in the visible portion of the electromagnetic spectrum (400 nm-700 nm) at a laser power of 0.001 to 12 watts, used with intermittent stops to control tissue temperature and biostimulate epithelial regeneration when used with or without substrates. A method of treating diseased tissue using a laser light in the green wavelength range (520-570 nm) at a laser power of 0.001 W to 5 W. A method of treating diseased tissue using a laser light in the IR wavelength range (700-1400 nm) at a laser power of 0.001 W to 5 W.

Abstract: The invention provides compositions and methods for topically inhibiting, reducing or preventing growth or biofilm formation of caries-, gingivitis- and/or halitosis-causing bacteria. The composition includes at least about 0.005% (w/v) of tea polyphenols, a pH modulating agent for maintaining a pH of the composition above about 6.5, and at least about 1% (w/v) of a 3-carbon to a 24-carbon sugar alcohol. Also provided are food products or supplements incorporating such compositions.

Abstract: The disclosure describes compositions for dental varnishes, methods of making the compositions, and methods of using the compositions, such as in the treatment and prevention of hypersensitivity in teeth.

Abstract: Dentifrice containing silica particles having a d50 median particle size from 4 to 25 ?m, a BET surface area of less than 10 m2/g, and a total mercury intrusion pore volume from 0.2 to 1.5 cc/g, are disclosed.

Abstract: A preparation in the form of a powder containing: (a) at least one carotenoid, (b) at least one modified starch, and (c) sucrose; wherein the at least one carotenoid is present in the powder in an amount of 1 to 25% by weight, based on the weight of the powder; and wherein the at least one carotenoid and the sucrose are present in the powder in a ratio by weight of 1:2 to 1:80.

Abstract: Adhesive compositions exhibiting antimicrobial properties, good stability, long shelf lives and enhanced release of antimicrobial agents are described. In certain versions, the compositions also exhibit relatively high fluid handling capacities. The adhesive compositions inhibit microbial growth by more than 2 log after 24 hours contact and particularly more than 3.5 log after 6 hours contact. Also described are various medical articles using such adhesives and related methods.

Abstract: A non-alcohol mouthwash composition includes a sweetener, a dispersing agent, a surfactant, an antimicrobial agent, a calcium ion source including calcium lactate, a phosphate ion source including monobasic sodium phosphate, a flavoring agent, a fluoride source, and water. The non-alcohol mouthwash composition includes about 0.001 weight percent of the calcium lactate and about 0.10 weight percent of the monobasic sodium phosphate, based on total weight percent of the non-alcohol mouthwash composition, and the composition has a pH greater than about 5.5.

Abstract: An oral care composition including a base formulation, sodium bicarbonate, and nisin, wherein the oral care composition removes biofilm from a tooth surface more effectively than the base formulation with the sodium bicarbonate or the nisin alone.

Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.

Abstract: Described herein are oral care compositions comprising a combination of zinc oxide and zinc citrate, and methods of preparing and using the same.

Abstract: The present invention provides vortioxetine pyroglutamate salt and pharmaceutical compositions comprising said salt.

Abstract: Disclosed herein are striped dentifrice compositions stable to color bleeding comprising at least one zinc ion source and a thickening system comprising xanthan gum present in the composition in an amount ranging from about 0.3% to about 1% by weight and carboxymethyl cellulose present in the composition in an amount ranging from about 1% to about 2% by weight. Further disclosed herein are methods for cleaning the surface of a tooth comprising applying the striped dentifrice compositions stable to color bleeding as disclosed herein.

Abstract: An oral care composition, including a mixture of antibacterial agents, the mixture of antibacterial agents including oleanic acid and eugenol at a 2:1 to 3:1 weight ratio.

Abstract: Provided are: a method for producing an oral composition suitable for treatment or prevention of a disease or symptom in the oral cavity; and an oral composition produced by the production method. The oral composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the oral composition produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.

Abstract: An oral care composition comprising: (a) arginine, in free or salt form; and (b) zinc oxide and zinc citrate. The oral care composition can reduce or inhibit biofilm formation in an oral cavity.

Abstract: Disclosed are oral care compositions having reduced tooth staining propensity and comprising in a pharmaceutically acceptable carrier, a cationic antimicrobial agent and an anti-stain agent comprising one or more materials from each of at least two of the following chemical groups: Group 1. anionic agents, Group 2. aldehydes, ketones, and other reactive carbonyl compounds and Group 3. nonionic ethoxylated surfactants. Examples of cationic antimicrobial agent include quaternary ammonium compounds such as cetylpyridinium chloride, cetyl pyridinium fluoride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride and domiphen bromide; chlorhexidine; and metal ion sources to supply metal ions such as stannous, zinc or copper.

Abstract: The present invention relates to an oral care composition for use in the treatment or prevention of erosive tooth demineralization, plaque, and caries. This oral care composition includes zinc lactate dihydrate, a stannous ion source, at least one phosphate salt, and a buffer system.