Abstract: The present invention provides peptides of pRb2/p130 or mutants or fragments thereof which inhibit cdk2 kinase activity. Method of inhibiting cdk2 kinase activity in cells with these peptides are also provided.
Abstract: The present invention provides methods of delaying development of HMFG-associated tumors using the anti-idiotype antibody 11D10, particularly in high-risk individuals having low tumor burden.