Abstract: A surgical system can include a surgical probe having a deflectable tip, and a plurality of guide arms that are movable so as to cause the tip to deflect. Thus, the surgical probe can be steered toward a target anatomical location. The surgical system can further include a control system that includes a free floating user interface, and a motion sensor that detects motion of the user interface. The control system is configured to cause the probe tip to deflect in response to the detected motion of the user interface.

Abstract: A biopsy system includes an elongate cannula coupled to and extending from a support structure, the cannula having a distal portion with a tissue receiving aperture in a side wall thereof, and an elongate hollow introducer sized and configured to be mounted to the support structure over the cannula. The support structure and a proximal portion of the introducer are respectively configured for providing releasable attachment of the introducer to the support structure over the cannula in a first attachment configuration, in which the distal portion of the cannula extends out an open distal end of the introducer with the tissue receiving aperture unobscured by the introducer, and in a second attachment configuration, in which the distal portion of the cannula extends out the open distal end of the introducer with the tissue receiving aperture partially obscured by the introducer.

Abstract: Provided herein is a device, a system, and a method of using the device and system to deliver non-contact thermal stimulation to the skin of a person and, by detecting evoked potentials in that person's central nervous system, to determine a neurological condition of the person.

Abstract: An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus.

Abstract: A device for separation and collection of tissue from an effluent stream of tissue and carrier fluid generated in a medical procedure comprises a housing (600) having an upper wall (601a), a lower wall (602a), a circumferential wall (612) extending between the upper wall and lower wall, an inlet aperture 606a for receiving the effluent stream and an outlet aperture (607a) for discharge of filtered fluid. The housing encloses a filter member (603a) positioned between said upper wall and said lower wall and comprising at least one filter receptacle (615), the upper wall comprising a viewing window (604) for viewing tissue collected in the filter member. The inlet aperture is located beneath the filter member, and the device comprises a fluid pathway (628) for delivering effluent stream received through the inlet aperture into a said filter receptacle from above the filter member. The device can be compact whilst nonetheless allowing visualisation of collected tissue.

Abstract: Disclosed herein are segmented MRI-compatible interventional devices, such as catheters and guidewires, that provide desired mechanical properties while avoiding undesired interactions with MRI fields. Disclosed devices can include helical wires with insulated breaks at intervals along each wire so that the insulated wire segments are individually short enough to avoid substantial resonance and heat being generated in the wires due to an applied MRI field. The segmented wires can be organized into a braided/woven tubular configuration or a non-braided intercalated/parallel tubular configuration that provides the desired mechanical properties similar to conventional metallic braided catheters. The helical wire segments can be insulated such that the wires do not touch each other at points where they cross over each other.

Abstract: Disclosed are methods for detecting neuronal oscillation in the spinal cord of a subject. The methods can be utilized to determine that the subject has a disease or disorder of the spinal cord. The methods are useful for treating or reducing the likelihood of pain in a subject by detecting neuronal oscillation in the spinal cord and, e.g., administering a therapeutic agent to the subject. The electrode (LFP) methods disclosed herein may also be utilized to screen for a therapeutic agent that decreases neuronal oscillation in the spinal cord using a non-human animal subject.

Abstract: A method and system for assisting clinicians in determining when and how to perform a lung recruitment procedure. The method includes a user configurable interface that an operator or institution can set up to correspond to best practices. Based upon the information entered into the configurable user interface, a method and algorithm automatically determines when a lung recruitment procedure should be instituted. The system can either manually or automatically enable the beginning of the lung recruitment procedure depending upon the clinician and facility preferences. The algorithm includes a plurality of process steps that are carried out in a clinically-relevant order to eliminate patient condition options and to provide the appropriate recommended actions prior to initiating the lung recruitment procedure.

Abstract: A medical system for removing far-field signals from a unipolar electrical signal is disclosed. In embodiments, the medical system comprises a catheter and a processing device communicatively coupled to the catheter. The catheter comprises a plurality of electrodes configured to sense a plurality of unipolar signals transmitted through tissue. The processing device is configured to: receive the sensed unipolar electrical signals, determine an electrode having a high level of contact with the tissue, and determine an electrode having a lower level of contact with the tissue than the electrode having the high level of contact with the tissue. Further, the processing device is configured to determine a sensed near-field electrical signal based on the unipolar electrical signal received from the electrode having the high level of contact and the unipolar electrical signal received from the electrode having the lower level of contact.

Abstract: A method of monitoring body sounds using a sensor including an array of microphones, the method includes acquiring a first sound produced by certain physiology using the array of microphones of the sensor, identifying a source of the first sound, performing an automatic auscultation of the source using the first sound, wherein the automatic auscultation including matching the first sound to an acoustic model stored in a memory, wherein the acoustic model corresponds to a physiology, generating an image representing the physiology using an image library, and determining a health condition using the physiology and the image.

Abstract: An apparatus useful for the rapid collection of blood from a subject (e.g., a blood vessel, such as the vein, artery or capillary bed of a bovine subject) and dispensing the blood therefrom into a test or collection device. In general, the apparatus comprises: (a) a body having a chamber formed therein, said chamber having an inlet and outlet, with said chamber configured to draw blood therein; (b) a hollow barrel connected to said chamber outlet; (c) an ejector operatively associated with said barrel; (d) a hollow needle connected to said body, with said hollow needle in fluid communication with said chamber through said inlet, so that blood can be rapidly drawn into said chamber through said needle. The needle is optionally removed and blood dispensed from the body into a test or collection device by actuating the ejector.

Abstract: A biological fluid collection device that is adapted to receive a blood sample having a cellular portion and a plasma portion is disclosed. After collecting the blood sample, the biological fluid collection device is able to transfer the blood sample to a point-of-care testing device or a biological fluid separation and testing device. After transferring the blood sample, the biological fluid separation and testing device is able to separate the plasma portion from the cellular portion and analyze the blood sample and obtain test results.

Abstract: A tri-point tissue-collection needle configured similarly to a fine-needle-aspiration needle is configured to excise intact tissue cores for collection. The distal tip is configured with three beveled points separated by cutting edges, where a single longer/more distal point is trailed by and circumferentially separated from a symmetrical pair of points, providing a bilaterally symmetrical needle cannula distal end. A stylet may be provided through a lumen of the needle during introduction into a patient body, where the distal end surface of the stylet may be configured to complement the tri-point needle end configuration.

Abstract: A wearable device has a core contraction sensor. Signals from the core contraction sensor are transmitted to a processor which analyzes the core contraction signals and determines if the user's core is contracted or relaxed. The processor can cause a computing device to output a sequence of tones in response to a core contraction signal. The sequence of tones can correspond to a song which can be played by performing a plurality of core contractions with durations that correspond to a duration of the notes in the song. Alternatively, the core muscles can be contracted to correspond to music heard by the user. The processor can output a score based upon the matching of the core contractions with the musical notes.

Abstract: A method of operating a tissue marking apparatus includes providing a tissue marking apparatus having a cannula, a stylet, and an imaging marker, the cannula having a peripheral wall forming a lumen and a lateral opening in the peripheral wall that is open to the lumen, and having a resilient end wall extending downwardly from the peripheral wall at a distal extent of the lateral opening, the stylet being slidably received within the lumen of the cannula for movement in the lumen; moving the stylet in a distal direction to expel the imaging marker from the lateral opening; and continue moving the stylet in the distal direction to deflect the resilient end wall of the cannula such that a distal end of the stylet passes beneath the resilient end wall to substantially close off the lateral opening of the cannula.

Abstract: The disclosed subject matter related to methods and apparatus for determining brain swelling in a patient as well as predicting an increase in intracranial pressure in the patient. The apparatus can include a transducer such as an ultrasound transducer communicatively connected to a controller via wires or via wireless communications device(s). A monitor and/or alarm device can be provided to notify a practitioner when the controller has determined brain swelling is occurring and/or when an imminent increase in intracranial pressure is likely to occur.

Abstract: A method for introducing a shaped portion of an elongate medical instrument into a body of a subject includes at least partially straightening the shaped portion of the elongate medical instrument. A retention element may be introduced into an interior of the shaped portion of the elongate medical instrument to place and/or maintain the shaped portion in an at least partially straightened configuration. Such straightening may be accomplished without application of external force to an exterior of the shaped portion. With the retention element in place, the shaped portion may be introduced to a desired location within a hollow interior of an internal organ. The retention element may then be removed to enable the shaped portion to return to its desired shape. A straightening apparatus includes a retention element that can place and/or maintain a shaped portion of an elongate medical instrument in an at least partially straightened configuration without assistance of external force.

Abstract: Systems and methods for identifying and treating patients with high frequency electrical signals. A representative method for identifying a patient as a candidate for pain treatment includes identifying a first sensory threshold, delivering an electrical signal to a neural population of the patient at a frequency in a frequency range of 1.5 kHz to 100 kHz and, while and/or after delivering the electrical signal to the patient, identifying a second sensory threshold of the patient. If the second sensory threshold is less than the first, the method can include identifying the patient as a candidate for receiving an electrical signal at a frequency in the foregoing range for pain treatment.

Abstract: A guidewire torquer comprising a handling body for handling of the guidewire torquer and guidewire holding surfaces oriented for engaging the guidewire from mutually opposite sides of the guidewire and holding the guidewire in an elastically tensioned, bent guidewire shape providing frictional fixation of the guidewire relative to the handling body. The guidewire holding surfaces project from an abutment plane defined by at least one abutment surface. A guidewire trajectory of the bent guidewire shape extends along and touches the guidewire holding surfaces is accessible from a direction in which the at least one abutment surface is facing. At least portions of the guidewire holding surfaces lean over towards or face the abutment plane for holding the guidewire adjacent to said abutment plane, and the guidewire holding surfaces are part of a single, rigid body portion.

Abstract: A catheter insertion device includes a handle, a needle, a guide wire, and a catheter. The handle may have a proximal region and a distal region. The distal region may include a slot between a top extension and a bottom extension, which extends through a distal end. The needle may have a proximal end positioned in the proximal region and a distal end extending from the distal region. The guide wire may have a proximal end positioned in the proximal region of the handle and a distal end positioned in a lumen of the needle. The catheter may be positioned coaxially over the needle with a proximal end connected to a catheter hub. The catheter hub may be slidably disposed in the slot to enable movement from a first position in the distal region to a second position distal of the distal region.