Abstract: Systems, device and methods treat target tissue to provide a therapeutic benefit to the patient. A tissue treatment device comprises a tissue treatment element constructed and arranged to treat target tissue, such as duodenal mucosa tissue.

Abstract: Stent graft comprising a stent (1) having a plurality of ring segments (3) arranged side by side and connected with each other by connecting webs (7) having a meandering pattern, and at least one membrane (2), characterized in that a plurality of connecting webs (7) between adjacent ring segments (3) are provided with flexible tongues (6), which are arranged in a form-closed manner in the connecting webs (7) and which are resiliently movable against the connecting webs (7), wherein the membrane (2) being clamped between flexible tongues (6) and connecting webs (7).

Abstract: A device and method of manufacturing and implanting a custom subtalar arthroereisis implant having side surfaces which are mirrored in topography with the sinus tarsi of a patient. The implant is formed using images of the patient standing in a weight bearing position with their sinus tarsi and the surrounding bone structure in an anatomically correct alignment. Once implanted, the implant urges and maintains the anatomically correct alignment thereby minimizing any patient tendency for abnormal motion between said patient's talus and calcaneus.

Abstract: According to one example, a tibial replacement assembly for a knee arthroplasty can be configured to couple to a resected proximal surface of a tibia of a human knee. The tibial replacement assembly can include a tibial tray and a first spike. The tibial tray can include a proximal surface and a distal surface opposing the proximal surface. The distal surface can be configured to be disposed on a resected proximal surface of a tibia. The first spike can be removably secured to the tibial tray and can extend generally distally away from the distal surface. The first spike can be configured to extend beneath the resected proximal surface of the tibia.

Abstract: A joint spacer, in particular a knee spacer and a hip spacer is provided which is long-lasting and is sufficiently cushioned and abrasion-resistant and which can also support locally very high loads.

Abstract: An implant (1) for modifying the tissue deformation during bone healing between two bone fragments (5; 6), with a first end piece (2) that can be fastened to a first bone fragment (5) with a longitudinal axis L1, and a second end piece (3) that can be fastened to a second bone fragment (6) with a longitudinal axis L2, wherein the first and second end pieces (2; 3) are loosely meshed with one another by means of n?1 parallel-connected tissue activators (4a; 4b) in each case to allow relative movement and the tissue activators (4a; 4b) are arranged to be perpendicular to the longitudinal axes L1 and L2 and preferably orthogonal thereto.

Abstract: The glenohumeral component of the invention comprises a first side and a second side, which are opposite each other and which, in an implanted state in which the glenohumeral component is free-floating with respect to a humerus and a glenoid of a human shoulder, are in contact respectively with an end portion of the humerus and with a glenoid component intended to be secured to the glenoid. The first side of the glenohumeral component includes a convex articular surface that is designed to articulate with a concave bone surface prepared within the end portion of the humerus. The second side of the glenohumeral component includes a concave articular surface that is designed to articulate with a convex articular surface of the glenoid component. The corresponding shoulder prosthesis is thus reversed.

Abstract: The present invention refers to an osteochondral local prosthetic insert for partial humeral joint reconstitution by reconstitution of the bone anatomical sphericity to treat bone lesions, in particular Hill-Sachs lesions. The local osteochondral prosthetic insert is a rigid monolithic body having a truncated-cone shape, the proximal diameter greater than the distal diameter, the proximal end of convex shape and rounded at the corners, and a tapered distal end. The lateral surface of the insert shows in the middle-distal part a non-return shaping that allows the maintenance of the position defined in the surgical operation. The proximal end is convex in order to better adapt to the local bone sphericity and has recesses for the manipulation and positioning through dedicated tools.

Abstract: A method for performing a diagnostic or therapeutic procedure on a partial occlusion within a blood vessel, includes positioning a guide having a sensor configured and adapted to measure at least one of pressure, volume or flow within a blood vessel, advancing the guide through an at least partial occlusion within the blood vessel such that the sensor is downstream of the occlusion, measuring at least one of pressure, volume or flow downstream of the occlusion using the sensor and analyzing data obtained from the sensor to assist in determining the viability of tissue of the blood vessel downstream of the occlusion.

Abstract: The invention relates to a foot module (7) for an exoskeleton structure, comprising an ankle joint (72), a first support plate (732) designed to be supported on the top of a boot of the user, when the foot module (7) is attached to the foot of the user, a second support plate (735) capable of being disposed under the sole of the boot, a first segment (731) connecting the ankle joint (72) to the first support plate (732) and a second segment (733) connecting the first support plate (732) to the second support plate (735), the first segment (733) and the second segment (735) forming a spring capable of being compressed when the boot is in contact with the ground (S) and being expanded when the boot is not in contact with the ground (S).

Abstract: Devices, systems and/or methods for repairing a lacerated tendon or ligament adjacent a repair site. In one embodiment, a repair device includes an elongated flexible structure and multiple anchors, the multiple anchors pre-positioned with the elongated flexible structure. The repair device may be coupled to the tendon or ligament at the repair site with a delivery device. The repair device may be pre-positioned in a cartridge such that the cartridge is loaded into the delivery device. The lacerated tendon or ligament is positioned within a cradle portion of the delivery device such that the tendon is positioned between the cradle portion and the cartridge that holds the repair device. The delivery device may then be triggered to actuate and drive the repair device from the cartridge to couple to the lacerated tendon or ligament. In this manner, the repair device may be anchored to the lacerated tendon.

Abstract: A total knee replacement prosthesis assembly (10) comprising a femoral component (20), a tibial component (30) having a tibial platform (32), and a bearing component (40), the bearing component having an inferior side (40b) and a superior side (40a), the bearing component being adapted to be arranged between the femoral component and tibial platform when assembled, the tibial platform having a post (36) upstanding from it and the bearing component having a post recess (46) in its inferior side for receiving the post, the bearing component being rotatable about the post when assembled, the post and bearing component each having a transverse bore and the assembly further comprising an axle (60), at least part of the axle being received through the transverse bore (38) in the post when assembled and at least part of the axle being received through the transverse bore (52) in the bearing component when assembled, the axle being configured to provide an axis of rotation between the femoral component and bearing co

Abstract: The disclosure describes implantable bioprosthesis and constructs having an implantable woven ribbon with at least one integrated suture.

Abstract: An implantable prosthetic valve has an upper frame section and a lower frame section. The upper frame section has a plurality of struts and a first leaflet receiving surface at a lower portion of the upper frame section. The lower frame section has a second leaflet receiving surface at an upper portion of the lower frame section. An edge of a flexible leaflet is disposed between the first and second leaflet receiving surfaces to attach the leaflet to the upper and lower frame sections.

Abstract: A method for coupling a body conduit to tissue includes engaging an implant about an outer surface of a catheter. The implant receives a bioactive agent having tissue growth properties. The method involves inserting the catheter through the body conduit and into a tissue opening across a resected area, positioning the implant in the resected area, inflating a balloon to anchor the catheter within the tissue opening such that the implant bridges the body conduit and the tissue opening across the resected area, and maintaining the catheter and the implant in vivo to enable the bioactive agent to secure the implant in the resected area to permanently bridge the body conduit and the tissue opening.

Abstract: A method of using an implantable device provides an implantable device including a plurality of links (113, 115, 117, 119), a device closure pin (111), a lock-in unit (103) attached and located between two links, and a quick release unit (105) attached and located between two links. The plurality of links (113, 115, 117, 119), lock-in unit (103) and release unit (105) are constructed in a closed contour. The closed contour of the implantable device, in a rigid state (151), is a figure eight comprised of two arcs (125, 127) and two connected interconnecting sections (131, 133).

Abstract: The orthopedic implant locking system may include an eccentric tibial stem having an engagement rod selectively threadingly engageable with a tibial baseplate, a lock housing securable in rotatable and substantial vertical constrained relation relative to the tibial stem, and an extension lock selectively threadingly engageable with the lock housing and including an inner passage keyed to selectively slidably engage the engagement rod in flush engagement therewith. The extension lock may extend or contract in response to rotational movement of the lock housing simultaneously while the extension lock remains in substantial non-rotatable relation relative to the tibial stem.

Abstract: A prosthetic heart valve can include an outer support assembly, an inner valve assembly, which define between them an annular space, and a pocket closure that bounds the annular space to form a pocket in which thrombus can be formed and retained. Alternatively, or additionally, the outer support assembly and the inner valve assembly can be coupled at the ventricle ends of the outer support assembly and the inner valve assembly, with the outer support assembly being relatively more compliant in hoop compression in a central, annulus portion than at the ventricle end, so that the prosthetic valve can seat securely in the annulus while imposing minimal loads on the inner valve assembly that could degrade the performance of the valve leaflets.

Abstract: A shoulder implant system includes a humeral stem implant, a humeral neck implant component, a humeral head implant component, and a glenoid implant. The humeral stem implant has a fin coupled to an exterior surface thereof that is inwardly tapered at an angle relative to vertical. At least a portion of the fin forms a wedge that directly engages and compacts cancellous bone during installation of the humeral stem implant. The humeral neck implant component is configured to be coupled with the humeral stem implant. The humeral head implant component is configured to be coupled to the humeral stem implant via the humeral neck implant component. The glenoid implant has a plurality of peripheral pegs. Each of the peripheral pegs has a plurality of sets of resilient lobes.

Abstract: Provided is an implant receiving apparatus (10) comprising a core (20), the core defining a first end (30) and a second end (40), a wall (50) comprising inner surface (60) and outer surface (70) and a centerline (80) extending centrally of and between the ends (30, 40), the size and shape of the core (20) defining a socket or cavity (90) adapted to receiving an implant engaging member (100), wherein the wall comprises at least one threaded bore (110) for engaging a screw retainer, the bore traversing through the wall from the inner surface to the outer surface. Also provided is an implant engaging member, an implant system comprising both an implant engaging member and implant receiving apparatus as well as kits comprising an implant receiving apparatus.