Abstract: A method for alleviating, preventing or treating symptoms of a viral infection such as common cold and flu, comprising administering to a subject in need thereof at least one solid form that releases molecular hydrogen upon exposure to the subject's gastric juice.
Abstract: A water-based liquid cosmetic comprising: sodium polyaspartate; at least one brilliant powder selected from the group consisting of a glass powder coated with a metal or a metal oxide, an aluminum powder, and a resin film powder coated with a metal; a water-soluble dispersant; and at least one metal oxide selected from the group consisting of yellow iron oxide, red iron oxide, black iron oxide, titanium dioxide, titanium oxynitride, and Prussian blue.
Abstract: Foamable formulations of agriculturally active ingredients are provided, as well as methods for using them. The formulations allow improved delivery active ingredients by the ability to deliver high amounts of active ingredient with a low volume of formulation used.
Type:
Grant
Filed:
May 28, 2020
Date of Patent:
May 17, 2022
Assignee:
FMC Corporation
Inventors:
Timothy M. Martin, Shawn Grant, Neil Destefano, Adam Prestegord, Michael Harper
Abstract: Disclosed herein is a technology for healing bone defects using bioactive silicate glass (BSG) and a 3D osteomimetic composite porous scaffold containing microspheres comprised of poly(lactide-co-glycolide) (PLGA).
Abstract: The present invention may provide an oil in water (O/W) cosmetic composition having water resistance and ease of facial cleansing, using an A-B-A type triblock copolymer which is included in the cosmetic, and thus may adjust the surfactant power. Further, it is possible to provide a method for imparting water resistance and ease of facial cleansing, using the A-B-A type triblock copolymer.
Type:
Grant
Filed:
October 30, 2019
Date of Patent:
May 17, 2022
Assignee:
COSMAX, INC.
Inventors:
Ji Hyun Lee, Jun Bae Lee, Sun Young Kim, Sung Yong Kim, So Youn An, Chun Ho Park, Myeong Sam Park
Abstract: The present invention relates to topical compositions comprising erythrulose and a caprylate, characterized in that the amount of the caprylate in the composition is 5 higher than the amount of erythrulose.
Type:
Grant
Filed:
June 28, 2018
Date of Patent:
May 10, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Christine Mendrok-Edinger, Sebastien Mongiat, Thomas Rudolph
Abstract: A magnetic microparticle drug carrier comprising mesoporous iron oxide is described. The drug carrier has an average diameter in a range of 0.5-1.2 ?m, a BET surface area ranging from 50-300 m2/g, and a pore volume ranging from 0.15-0.65 cm3/g. The drug carrier is made using a hard mesoporous silica template which is completely removed from the deposited iron oxide. The drug carrier may be loaded with high amounts of hydrophilic anticancer chemotherapeutic drugs and/or hydrophobic hormonal anticancer drugs, and released in a pH-controlled manner inside cancerous cells. Compared to free drugs, the drug microparticle carrier displays enhanced drug accumulation inside tumor tissues, deeply penetrates into a tumor region and kills the tumor cells inside. The designed carriers described here entrap and release different kinds of anticancer drugs in a controlled manner for synergistic combinatorial chemo/hormonal cancer therapy.
Type:
Grant
Filed:
June 23, 2020
Date of Patent:
May 3, 2022
Assignees:
National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
Abstract: A bioactive glass composition for use in treating bone cancer includes 0.5-10 mol % gallium oxide or 1.0-20 mol % gallium nitrate/halide; 25 to 75 mol % silicon dioxide; 10 to 30 mol % calcium oxide and/or strontium oxide; up to 30 mol % sodium oxide; and up to 15 mol % phosphorous pentoxide. It may further comprise magnesium and/or potassium oxide. The bioactive glass composition may be positioned within a patient's bone post-surgery to promote apatite formation and to release gallium ions having a toxic effect on any remaining cancerous cells.
Abstract: The present invention provides a particle comprising pirfenidone and a lipid, particularly magnesium stearate, and having a mean particle diameter of 5 ?m or less, and a powder formulation comprising the particle and a carrier.
Abstract: A method for producing a nonaqueous composition for external use on the skin including a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed in an oil phase, the method including the steps of: dissolving a surfactant in an oil phase to obtain a surfactant solution; mixing the obtained surfactant solution with a strongly hydrophilic amphiphilic solid active ingredient to obtain a suspension; and allowing the obtained suspension to stand still to obtain a transparent composition. Unlike conventional methods for preparing S/O formulations, the strongly hydrophilic amphiphilic solid active ingredient can be solubilized in an oil phase without the process of emulsification and freeze drying.
Type:
Grant
Filed:
October 5, 2018
Date of Patent:
April 12, 2022
Assignees:
CHANEL PARFUMS BEAUTE, KYUSHU UNIVERISTY, NATIONAL UNIVERSITY CORPORATION
Abstract: The present invention relates generally to a feed supplement preparation for administration to ruminant animals and, more particularly, to a formulation for an oral bovine supplement for neonatal calves that delivers naturally occurring caffeine, antioxidants and other electrolytes in a stable liquid form of moderate viscosity.
Type:
Grant
Filed:
August 30, 2018
Date of Patent:
April 12, 2022
Assignee:
TechMix, LLC
Inventors:
Nathan C. Upah, Aaron N. Fritchen, Dennis M. McKilligan, Bradley W. Kolstad
Abstract: An elastomer improves the feel of inorganic powder on the skin. An emulsion cosmetic is characterized by containing: (A) 0.5-20 mass % of an inorganic powder having an elastomer coating layer containing (a1) and (a2); and (B) 20-80 mass % of an oil component. The elastomer is characterized by comprising: (a1) a silicone polymer having an amino group; and (a2) a carboxyl group-containing silicone polymer or a carboxyl group-containing acrylic polymer, wherein the molar ratio of the amino group to the carboxyl group, Y/X is in the range of 0.1-1.2 (Y is the molar amount of the carboxyl group contained in the component (a2), and X is the molar amount of the amino group contained in the component (a1)).
Type:
Grant
Filed:
November 6, 2018
Date of Patent:
March 15, 2022
Assignee:
SHISEIDO COMPANY, LTD.
Inventors:
Mayo Shinke, Shoko Ogawa, Tomo Osawa, Tomoko Ikeda
Abstract: An antimicrobial article, a cell culture article, an antithrombotic article, or a biopharmaceutical article that can reduce adhesion of proteins, blood components, cells, or bacteria containing a copolymer that contains a polymerized unit (A) represented by —CH2—CHOH— and a polymerized unit (B) represented by —CH2—CX2—, wherein Xs are the same as or different from each other, and are each an alkyl group having a linear, branched, or cyclic structure, and optionally containing an oxygen atom between carbon atoms, an alkoxy group having a linear, branched, or cyclic structure, and optionally containing a hetero atom between carbon atoms, a siloxy group having a carbon number of 3 or greater, an ester group containing an aromatic ring or an alkyl group and having a linear, branched, or cyclic structure, or H, excluding those in which both Xs are H.
Type:
Grant
Filed:
August 2, 2018
Date of Patent:
February 15, 2022
Assignees:
NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY, DAIKIN INDUSTRIES, LTD.
Abstract: Therapeutically-active compositions and formulations for treating pain, pruritus, irritation, inflammation, and tissue damage due to the irritation and inflammation, and therapeutically-active compositions and formulations for wound management, including wounds that are at high risk for infection. Strontium and beta hydroxybutyrate based compositions and formulations which can be topically applied.
Abstract: The invention provides CaO2 nanoparticles having a pH-responsive coating for use in a method of adjuvant therapy of hypoxic tumour cells or tissues. The nanoparticles find particular use in enhancing cancer therapies that depend on oxygen to exert their effect, such as photodynamic therapy (PDT), sonodynamic therapy (SDT), and radiotherapy. The invention also provides pharmaceutical compositions containing the coated CaO2 nanoparticles, together with at least one photosensitiser, sonosensitiser, or radiosensitiser and, optionally, at least one pharmaceutical carrier or excipient.
Type:
Grant
Filed:
May 4, 2018
Date of Patent:
February 1, 2022
Assignee:
UNIVERSITY OF ULSTER
Inventors:
Anthony Mchale, John Callan, Yingjie Sheng
Abstract: An avermectin-based topical formulation is disclosed which is useful for prevention and treatment of head lice (Pediculus humanus capitis). This topical formulation may be formulated as a shampoo-condition which comprises an effective amount of avermectin, solubilizers, suspending agents, preservatives, nonionic surfactants, humectants, a silicone compound, and water. Also disclosed are methods of using the topical formulations disclosed within this specification to treat either a susceptible or treatment-resistant strain of lice, as well as uses in the manufacture of a medicament for treating or preventing a lice infestation from a susceptible or treatment-resistant strain in a human patient.
Abstract: Provided herein are methods of accelerating, promoting, or restoring hair growth, comprising administering to a subject in need thereof an effective amount of a compound of formula (I). Also provided are compositions comprising the compound of formula (I).
Type:
Grant
Filed:
August 25, 2017
Date of Patent:
January 4, 2022
Assignee:
The Regents of the University of California
Inventors:
William E. Lowry, Heather R. Christofk, Aimee Flores
Abstract: Disclosed is a novel air purification composition with antiviral and bactericidal functions, the composition at least comprising the following components in percentage by weight: 0.3%-1% of a black poplar essential oil, 0.1%-1% of a tea tree essential oil, 0.1%-0.5% of a Cupressus funebris essential oil, 0.1%-1% of an Artemisia apiacea essential oil, 0.1%-10% of a Sophora flavescens extract, 0.1%-5% of a ginger extract, 5%-30% of a Cupressus funebris hydrolate, 0.5%-1% of a hyperbranched amino polymer, 0.5%-5% of a surfactant, and the balance being water.
Abstract: The present invention relates to a herbicidal composition comprising specific quinolinecarboxylic acids selected from quinclorac and quinmerac. The invention also relates to methods and uses for controlling undesirable vegetation, in particular in crops.
Type:
Grant
Filed:
July 6, 2016
Date of Patent:
December 28, 2021
Assignee:
BASF AGRO B.V.
Inventors:
Helmut Kraus, Bernd Sievernich, Mariano Etcheverry, Richard R. Evans, Ryan Louis Nielson, Cyrill Zagar, Rex A. Liebl
Abstract: A cosmetics composition having improved water absorbability and oil absorbability is provided. The cosmetics composition effectively controls sweat and sebum, thereby making it possible to improve persistence of make-up and to keep skin from looking dull.
Type:
Grant
Filed:
December 24, 2019
Date of Patent:
December 28, 2021
Assignee:
CQV CO., LTD.
Inventors:
Ki-Jung Kim, Sang-Hoon Kim, Kwang-Choong Kang, Byung-Ki Choi, Kwang-Soo Lim, Kil-Wan Chang