Abstract: Methods of treating subjects having diseases, disorders, or conditions, including cancer and immune- and inflammatory-related disorders, via the administration of IL-10 in combination with one or more additional agents, and methods and models associated therewith, are provided.
Type:
Grant
Filed:
November 7, 2014
Date of Patent:
August 16, 2022
Assignee:
ARMO BIOSCIENCES, INC.
Inventors:
John Brian Mumm, Ivan Ho Chan, Martin Oft
Abstract: Disclosed herein are methods of reducing a symptom of respiratory disease in a pre-weaned milk-fed mammal by orally administering an isolated antibody that specifically binds the interleukin-10 peptide or an anti-interleukin-10 antibody. Also included are methods of reducing mixing stress in human and non-human mammals by administering an isolated antibody that specifically binds the interleukin-10 peptide or an anti-interleukin-10 antibody. Further included are milk and food compositions including the interleukin-10 peptide or anti-interleukin-10 antibody.
Type:
Grant
Filed:
October 9, 2019
Date of Patent:
May 3, 2022
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION
Inventors:
Mark Eric Cook, Jordan Marshall Sand, Sheila Mary McGuirk, Jane Ellen Rieman, Sarah Marie Raabis
Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury.
Type:
Grant
Filed:
August 14, 2017
Date of Patent:
March 1, 2022
Assignee:
Astute Medical, Inc.
Inventors:
Joseph Anderberg, Jeff Gray, Paul McPherson, Kevin Nakamura, James Patrick Kampf
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