Abstract: A method for applying cold atmospheric plasma treatment on target tissue. The method comprises the steps of selecting through a graphical user interface on a display a particular cancer cell line associated with the target tissue, retrieving in response to the selecting, with a computing device connected to the display, settings data from a database of cell line data and associated settings data in a storage, applying, with the computing device, the retrieved settings data to a cold atmospheric plasma system, and treating cancer tissue with cold atmospheric plasma at the retrieved settings. The method may further comprise displaying the retrieved settings on a display.

Abstract: An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.

Abstract: Various control systems for controlling a surgical system according to detected airborne particulate characteristics are disclosed.

Abstract: A method and system for mapping tissue and producing lesions for the treatment of cardiac arrhythmias in a non-thermal and optimal manner, minimizing the amount of energy required to selectively stun or ablate the target tissues. Energy may be delivered only at the moment(s) of best device position and proximity of an electrode to target tissue, and only during a time in the cardiac cycle determined to be optimal for reversible or irreversible effects. A method may include determining timing of the cardiac cycle and an optimal time within the cardiac cycle for energy delivery, evaluating proximity between at least one energy delivery electrode and the target tissue, and delivering pulsed field energy from the at least one energy delivery electrode to the target tissue when, during the optimal time for energy delivery, the at least one energy delivery electrode is in close proximity with the target tissue.

Abstract: A handpiece for a surgical instrument having a valve position sensing circuit arranged to detect the position of a valve arranged to control the flow of fluid through the suction lumen of the instrument. The distal end of the handpiece is arranged to couple to a cutting accessory. The handpiece comprises: a housing; a suction lumen within the housing extending from the distal end of the handpiece to a proximal end of the handpiece; a valve arranged to control the flow of fluid through the suction lumen; and a valve position sensing circuit arranged to detect a position of the valve. The valve position sensing circuit can be used to alert a surgeon if the valve is closed when it would be preferable for it to be open. For example, if the motor is overheating, the in-joint temperature is too high, or the RF component is activated.

Abstract: Various aspects of a generator, ultrasonic device, and method for estimating a state of an end effector of an ultrasonic device are disclosed. The ultrasonic device includes an electromechanical ultrasonic system defined by a predetermined resonant frequency, including an ultrasonic transducer coupled to an ultrasonic blade. A control circuit measures a complex impedance of an ultrasonic transducer, wherein the complex impedance is defined as Z g ( t ) = V g ( t ) I g ( t ) . The control circuit receives a complex impedance measurement data point and compares the complex impedance measurement data point to a data point in a reference complex impedance characteristic pattern. The control circuit then classifies the complex impedance measurement data point based on a result of the comparison analysis and assigns a state or condition of the end effector based on the result of the comparison analysis.

Abstract: A system for treating uterine tissue comprises an elongated shaft having a proximal end, a distal end, and a longitudinal axis extending between said proximal and distal ends. An energy applicator at the distal end of the elongated shaft is actuatable between a non-expanded shape to be inserted through a patient's cervical canal and an expanded shape to conform to the walls of the patient's uterus. A handle is coupled to a proximal end of the elongated shaft. The handle may include first and second moveable grips coupled to actuate the energy applicator with an upper spring and a lower spring disposed to urge the first and second moveable grips to move apart. An inflatable seal may be located at a distal end of the elongated shaft with a thermally insulating sleeve disposed over the elongated shaft proximal to the inflatable seal.

Abstract: A microwave ablation probe including a probe body including a shielded portion and a radiation window that is at least partially transparent to microwave energy. The shielded portion includes a cannula, a coaxial cable within the probe body, and an antenna comprising a radiating portion for emission of microwave energy at a distal portion of the probe body, wherein the radiating portion is aligned with the radiation window. The probe body defines an irrigation path configured to carry cooling fluid to and from the distal portion of the probe body. At least one wall defining the irrigation path comprises a heat exchange surface having an average radius, wherein a surface area of the heat exchange surface is larger than a surface area of a smooth surface with a radius equal to the average radius.

Abstract: An electrosurgical instrument includes jaws having an electrode configuration utilized to electrically modify tissue in contact with one or more electrodes. The instrument is removably connectable to an electrosurgical unit via an electrosurgical connector extending from the instrument and a receptacle on the electrosurgical unit. The electrosurgical instrument is rotatable without disrupting electrical connection to the electrodes of the jaws. One or more of the electrodes is retractable. The electrosurgical unit and instrument optimally seals and/or cuts tissue based on identifying the tissue and monitoring the modification of the tissue by the application of radio frequency energy.

Abstract: A device and a method for coagulation and/or dissection of biological tissue is disclosed. The device comprises an apparatus and an instrument electrically connected thereto. The instrument includes an operation circuit with a manually operated switch. An evaluation circuit of the apparatus provides an evaluation signal for the instrument. The apparatus can create a supply voltage or a supply current for the instrument. In the initial condition the evaluation signal comprises only one polarity. The evaluation signal is provided to a control circuit of the instrument in which a characteristic of the evaluation signal is adjusted depending on the operating condition of the switch. The evaluation circuit detects this characteristic and initiates the output of the supply voltage and changes the polarity of the evaluation signal according to the requested cutting mode. In the cutting mode the evaluation signal comprises at least temporarily also a second polarity.

Abstract: A radio frequency ablation system, includes a single frequency RF signal generator, control circuitry configured to set phases and amplitudes of a plurality of replicas of the RF signal, a plurality of non-linear amplifiers, configured to amplify the plurality of replicas of the RF signal, and to drive a respective plurality of ablation electrodes in a patient body with the amplified replicas. A processor is configured to receive a superposition of the plurality of replicas as a return signal from a body surface patch electrode, and to adaptively adjust phases and amplitudes of the amplified replicas in response to the return signal with the control circuitry to zero crosstalk currents. In a tissue contact check mode of operation the phases of the amplified replicas are identical, and in an ablation mode of operation the phases of the amplified replicas differ from one another.

Abstract: Electrosurgical systems and components thereof configured to deliver RF energy to a target site of a human or other animal patient with selectable RF energy delivery profiles, temperature sensors and controls, and/or electrodes configured to more uniformly or effectively delivery energy to target tissue.

Abstract: The present disclosure provides electroporation systems and methods of energizing a catheter for delivering electroporation. A catheter for delivering electroporation includes a distal section and an electrode assembly. The distal section is configured to be positioned in a vein within a body. The vein defines a central axis. The electrode assembly is coupled to the distal section and includes a structure and a plurality of electrodes distributed thereabout. The structure is configured to at least partially contact the vein. Each of the electrodes is configured to be selectively energized to form a circumferential ring of energized electrodes that is concentric with the central axis of the vein.

Abstract: A method of ablation includes storing in a memory a pre-determined relation between lesion size and amount of ablative energy, for each of one or more selected temperatures. Using a processor, user input is received, that indicates a lesion size and a tissue temperature. Based on the relation, an amount of energy is determined, that matches the lesion size and the tissue temperature. An ablation probe is controlled to apply the amount of ablative energy that matches the selected lesion size.

Abstract: To determine appropriate treatment doses of cold atmospheric plasma (CAP), the Canady Helios Cold Plasma Scalpel was tested across numerous cancer cell types including renal adenocarcinoma, colorectal carcinoma, pancreatic adenocarcinoma, ovarian adenocarcinoma, and esophageal adenocarcinoma. Various CAP doses were tested consisting of both high (3 L/min) and low (1 L/min) helium flow rates, several power settings, and a range of treatment times up to 5 minutes. The impact of cold plasma on the reduction of viability was consistently dose dependent, however the anti-cancer capability varied significantly between cell lines. While the lowest effective dose varied from cell line to cell line, in each case an 80-99% reduction in viability was achievable 48 hours after CAP treatment. Therefore, it is critical to select the appropriate CAP dose necessary for treating a specific cancer cell type.

Abstract: The invention generally relates to systems and methods for therapeutically modulating nerves in or associated with a nasal region of a patient for the treatment of a rhinosinusitis condition.

Abstract: The present disclosure provides catheters for electroporation systems. One catheter includes a plurality of catheter electrodes disposed along a portion of a distal end of the electroporation catheter. The plurality of catheter electrodes includes a plurality of first type catheter electrodes adapted for use with an electroporation generator during an electroporation procedure and a plurality of second type catheter electrodes adapted for use with an electroporation generator during an electroporation procedure and for use with a diagnostic subsystem. The plurality of first type catheter electrodes is positioned at a distal end of the electroporation catheter. Each second type catheter electrode is adjacent another second type catheter electrode.

Abstract: An electrosurgical forceps includes first and second shafts configured to rotate about a pivot to move jaw members between an open position and a closed position. A knife deployment mechanism is operably coupled to a knife and is configured to move the knife between a retracted position and an extended position. A knife lockout is configured to move between a first position wherein the jaw members are in the open position and movement of the knife from the retracted position to the extended position is prevented, a second position wherein the jaw members are in the closed position and movement of the knife from the retracted position to the extended position is permitted, and a third position wherein the jaw members are in the closed position and movement of the knife from the retracted position to the extended position is prevented.

Abstract: The plasma sensor monitors parameters characterizing the condition of the plasma during the treatment phase and/or the change thereof in order to recognize a prefiguring or already occurred interruption of the plasma in this manner and to avoid this interruption and, in the ideal case, avoid this by already changing the voltage form previously. The mentioned mechanisms can be used by the control device (22) also during a pulse packet. The length of each pulse packet is adapted at each change of the voltage form according to their characteristics in order to guarantee a constant average power.

Abstract: A treatment system includes an energy treatment tool and a power supply device. The energy treatment tool includes respective first and second grasps configured to be coupled with one another and are capable of pivoting with respect to one another so as to grip a treatment target therebetween. A plurality of bipolar electrodes is attached to the respective first and second grasps. The plurality of bipolar electrodes receives a high-frequency current to flow through the treatment target so as to develop a first temperature distribution in the treatment target. A treatment energy source is configured to be coupled to one of the respective first and second grasps and receives electric energy to generate treatment energy different from the high-frequency current and to apply the generated treatment energy to the treatment target so as to develop a second temperature distribution in the treatment target.