Abstract: A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk; a first reagent dispensing mechanism that dispenses a reagent to reaction cells on the reaction disk; a photometer that irradiates a reaction solution in the reaction cell with light; a reaction cell cleaning mechanism; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to detect transmitted or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.

Abstract: In some embodiments, a kit for preparing a cell suspension may include a device and a housing. The device may include a first label identifying a first reservoir of the device for use with a first portion of a tissue processing method and a second label identifying a second reservoir of the device for use with a second portion of the tissue processing method. The housing includes a first housing portion configured to store a first set of components associated with the first portion of the tissue processing method. The first housing portion includes a first visual indicator associated with the first label of the device. The second housing portion may be configured to store a second set of components associated with the second portion of the tissue processing method. The second housing portion may include a second visual indicator associated with the second label of the device.

Abstract: A metering head for a metering machine having a carrier having parallel attachments for picking up pipette tips wherein each attachment has a tube having a supporting protrusion at the bottom end at least one sleeve which surrounds the tube and can be axially shifted on the tube, and at least one elastomer O-ring which surrounds the tube a pressure plate above the sleeves having a plurality of first holes through which the tubes extend, wherein the pressure plate can be shifted along the tubes from a release position into a clamping position where the sleeves are pressed, at the bottom ends, against the adjacent O-rings, and the O-rings are expanded to clamp pipette tips; and a first shifting apparatus connected to the pressure plate moving the pressure plate between the release position and clamping position.

Abstract: The present invention relates to a vial device for storing a specimen which containing exfoliative cells of a human body and for being used in smearing the exfoliative cells. More specifically, the present invention relates to a technology, which may be used with an exfoliative cell processing device for smearing exfoliative cells, for moving manually or automatically in the exfoliative cell processing device with containing the exfoliative cells so as to provide a part of the exfoliative cells to a slide of the exfoliative cell processing device. The present invention has an advantage in that, due to a recess and a latching rib in the opening cap, the opening cap may be automatically separated from the container member without user operation through a rotating member of the exfoliative cell processing device.

Abstract: The invention provides a method for selecting a color for a chemistry or instrument based upon a parameter of a test, the method including: identifying a color corresponding to a parameter of a test for the parameter; selecting, if the color corresponding to the parameter has not previously been used for another parameter, the color for designating a chemistry or an instrument as corresponding to the parameter; selecting, if the color corresponding to the parameter has previously been used for another parameter, a different color other than the color for designating a chemistry or an instrument as corresponding to the parameter, wherein the selecting a color other than the color comprises identifying a color having a measure of change in visual perception of the different color against other previously selected colors a predetermined value from the other previously selected colors; and utilizing the selected colors for parameters across both chemistries (102, 104, 105) and instruments (101, 103) that are util

Abstract: Described is a multi-channel fluidic device that includes a diffusion-bonded body having a device surface and a plurality of fluid channels. Each fluid channel includes a channel segment defined in a plane that is parallel to the device surface and parallel to each of the planes of the other channel segments. The plane of each channel segment is at a depth below the device surface that is different from the depth below the device surface for the other planes. Each channel segment may have a volume equal to the volume of each of the other channel segments. One of the fluid channels may include a plurality of channel segments serially connected to each other and each defined in a plane that is different from the planes of the other channel segments.

Abstract: The present application provides a gas inlet structure for a reagent kit, which includes a gas inlet connecting pipe and a plugging pipe arranged at one end of the gas inlet connecting pipe. The plugging pipe is provided with a gas nozzle plug, and the plugging pipe is in interference fit with the gas nozzle plug. The gas nozzle plug is provided with a gas inlet blind hole that is arranged along an axis direction of the gas nozzle plug, and an opening end of the gas inlet blind hole faces the gas inlet connecting pipe.

Abstract: Described are exemplary embodiments of a syringe identification system for use with a positive displacement pipette, such as a handheld powered positive displacement pipette. An exemplary syringe identification system may include a sensor, such as a color sensor, that is located at or near a distal end of the pipette and arranged such that the sensor is operative to read an identifying marking(s) on a syringe that has been installed to the pipette. The sensor may be a color sensor having an illumination source and configured to read a color code on the syringe. The color code may be usable to identify the syringe to the pipette.

Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.

Abstract: Embodiments in accordance with the present disclosure are directed to apparatuses used for reaction screening and optimization purposes. An example apparatus includes a plurality of reaction vessels, a dispensing subsystem, at least one reactor module, an analysis subsystem, an automation subsystem, and control circuitry. The dispensing subsystem delivers reagents to the plurality of reaction vessels for a plurality of reaction mixtures having varied reaction conditions. The at least one reactor module drives a plurality of reactions within the plurality of reaction vessels. The analysis subsystem analyzes compositions contained in the plurality of reaction vessels. The automation subsystem selectively moves the plurality of reaction vessels from a location proximal to the dispensing subsystem to the at least one reactor module based on experimental design parameters. And, the control circuitry identifies optimum reaction conditions for a target end product based on the analysis.

Abstract: An automatic analyzer keeps the inside of a reagent cooler that stores a reagent vessel clean. The automatic analyzer includes: a reagent cooler that stores a reagent vessel containing a reagent to be reacted with a sample at a predetermined temperature. A reagent vessel replacement unit includes an opening configured to put the reagent vessel into and take the regent vessel out of the reagent cooler, wherein the opening is opened and closed to replace the reagent vessel. A positive pressure unit positively pressurizes the inside of the reagent cooler with respect to a periphery of the reagent cooler when the opening is opened.

Abstract: A dispensing container and adapter system for use with a planetary mixer is disclosed. The dispensing container has a longitudinal axis and a transverse axis. The dispensing container may include a nozzle and a removable cap to cover the nozzle. The removable cap may have a first width dimension measured along the transverse axis. The dispensing container may include a body having a second width dimension measured along the transverse axis. An adapter may receive the dispensing container. The adapter may include a cavity to receive the removable cap. The cavity may have a cavity width that exceeds the first width dimension. The adapter may also include a recess for receiving a portion of the dispensing container. The recess may extend from the cavity. At least a portion of the recess may have a width dimension smaller than both the first width dimension and the second width dimension.

Abstract: A method of washing an aspiration probe of an in-vitro diagnostic system is disclosed. The aspiration probe comprises an outer surface and an inner surface forming an inner space for receiving a fluid. The method comprises dipping the aspiration probe into a first wash fluid so that the outer surface is immersed at least in part into the first wash fluid, aspirating an amount of the first wash fluid into the inner space of the aspiration probe, propagating an ultrasonic vibration to the outer surface of the aspiration probe via the first wash fluid, and rinsing the outer surface and the inner surface of the aspiration probe with a second wash fluid. Further, an in-vitro diagnostic method and an in-vitro diagnostic system are disclosed.

Abstract: A reagent container includes a base defining a plurality of wells having openings exposed at an upper surface of the base and a tube receptacle. The plurality of wells include a first set of wells and a second set of wells. Each well of the first set of wells has an opening to a well bore and a channel in communication with the well bore. The opening has a first portion disposed over the well bore and a second portion disposed over the channel. The first portion has a larger area than the second portion. An angle defined by tangents to the inner surface of the first and second portions at a junction between the first and second portions is at least 100° and not greater than 180°. The reagent container further includes a top coupled over the top surface of the base and defining windows providing access to the openings of the plurality of wells and the tube receptacle.

Abstract: A detection system for multi-index coagulation items, including a housing, a detection and heating module, a battery module, a touch display screen and a mainboard. The housing includes an upper housing and a lower housing, and is an enclosed space formed by the upper housing abutting the lower housing; the mainboard is disposed between the upper and the lower housing, and is arranged in the enclosed space; the touch display screen is disposed at the upper surface of upper housing, and is connected with the mainboard; the detection and heating module is disposed in the enclosed space, and is arranged at the front end of lower housing for connecting with the mainboard; the battery module is arranged at the bottom of terminal of lower housing, and is connected with the mainboard; and a detection inlet for inserting and placing a detection card is disposed at the front end of housing.

Abstract: Systems and techniques for detecting a target substance, such as THC, in a breath constituent sample are provided.

Abstract: In a sample pretreatment device, a container storage section (2) holds multiple containers, including a first well plate having wells in an N×M matrix form and a second well plate having N elongated wells whose length corresponds to M wells in one row of the first well plate or M elongated wells whose length corresponds to N wells in one column of the first well plate. A dispensing section (3) includes: a platform (30) on winch containers can be placed; a pipette unit (311, 312) including an M-channel tip corresponding to M wells in one row of the first well plate or an N-channel tip corresponding to N wells in one column of the first well plate; and a pump unit (313) for suctioning/ejecting a liquid from/into a container on the platform through the pipette unit. A transfer section (4) transfers containers between the container storage section and the platform. A controller (5) controls operations of the dispensing section and the transfer section.

Abstract: Provided in part herein are pipette tip rack assemblies having one or more of the following features: (i) having a plurality of pipette tip receptacle plates, each plate having an array of pipette tips, stacked upon one another supported by a rack base; (ii) each plate having one or more projections from the proximal or distal surface and, optionally, orifices that oppose the projections of the next plate in the stack, and (iii) the rack base having a proximal surface with one or more orifices or projections that oppose the projections or orifices of the plate in the stack. Also provided are methods of dispensing pipette tips from pipette tip rack assemblies and manufacturing pipette tip rack assembly components.

Abstract: The disclosure provides a system and method to safely and efficiently store and transport process tubes in a carrier tray comprising prior to and during amplification of nucleotides in the process tubes. The process tube disclosed includes a securement region having an annular ledge, a neck, and a protrusion. The securement region of the process tube can secure the process tube in a port of the carrier tray, but still allows the process tube to adjust or float in order to align the process tube into a rigid heater well of a thermal cycler.

Abstract: Systems and methods for calibrating laboratory instruments. In an example, a laboratory instrument for testing patient specimens includes a testing apparatus configured to receive a cassette that includes a patient specimen or a quality control specimen. In response to determining that a quality control specimen is present, the instrument obtains a first measurement of a parameter. If the first parameter is outside an expected tolerance, the instrument ceases performing tests on all specimens, the instrument re-tests the quality control specimen to obtain a second measurement of the parameter. If the second measurement is within the expected tolerance, instrument resumes processing of the cassette. If the second measurement is outside the expected tolerance, the instrument indicates that recalibration or service is required.