Abstract: A method of improving structural stability of a ceramic core used in the casting of turbine components includes the steps of a) providing a die having a predetermined geometry which gives the ceramic core a shape corresponding to interior spaces in the turbine component; b) inserting elongated strengthening members into interior or more areas of the die corresponding to one or more of the interior spaces; c) injecting a ceramic slurry into the die so as to substantially enclose the strengthening members; and d) firing the ceramic slurry to form a hardened ceramic core. A ceramic core used in a high temperature gas turbine component casting process includes a ceramic body having a geometry corresponding to internal passages of a gas turbine component; and at least one elongated rod or tube incorporated in the ceramic body, the rod or tube comprised of a material which retains structural stability at temperatures in excess of about 2600.degree. F.

Abstract: A method of fabricating electron emission structures 30 having enhanced emission characteristics. The method comprising the steps of providing a substrate 10 having electron emission structures 5 thereon and having a gate layer 6 over the electron emission structures 5. Then modifying the electron emission structures with a focused beam to create modified electron emission structures 30 with enhanced emission efficiency.

Abstract: The invention provides methods for stimulating thrombocytopoiesis in a mammal comprising administering to the mammal an effective amount of modified C-reactive protein ("mCRP") or mutant protein expressing neo-CRP antigenicity. Methods for treating thrombocytopenia, and for promoting megakaryocyte growth and maturation in vitro are also provided. Kits and articles of manufacture are further provided which include mCRP or mutant protein expressing neo-CRP antigenicity.

Abstract: A nephelometer and nephelometer/turbidimeter combination of the type useful in automated chemical analyzers is provided. The combination includes a laser for generating a polarized laser beam having an S-wave component and a P-wave component. The beam is split by a beam splitter specially constructed so that a known proportion of one of the two polarized portions of the beam is directed to a reaction container. In the reaction container, a first polarized component of the laser beam is used in a nephelometric chemical analysis. The remainder of the laser beam passes through the beam splitter to a laser control light detector. Before the remainder of the laser beam reaches the laser control light detector, however, the polarized component which is not used in nephelometric chemical analysis is filtered out. The laser control detector uses the non-filtered portion of the laser beam to control the output of the laser.

Abstract: Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetics of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.

Abstract: A vacuum microdevice includes a first electrode, an insulating film, and a second electrode. The first electrode projects in a current radiation region on a substrate and has a sharp tip. The insulating film is formed on the surface of the first electrode except the tip of the first electrode. The second electrode is formed on the insulating film and has an electrode thickness which increases away from the tip of the first electrode.

Abstract: A combustible gas sensor having a pair of temperature sensor sections is here disclosed. One of the pair of temperature sensor sections is covered with porous oxidizing catalytic layers (23, 24) for oxidizing a combustible gas, and the other is not covered with the oxidizing catalyst layers. In the one temperature sensor section, the combustible gas is burned, and in the other temperature sensor section, the temperature of a gas to be measured is compensated. The temperature sensor sections each comprises temperature sensitive portions (13, 14) made of a dense ceramic material, resistors (21, 22) buried therein and having a positive resistance temperature coefficient, current leads (31, 32, 41, 42) and voltage leads (33, 34, 43, 44). A method for measuring the concentration of the combustible gas by the use of this combustible gas sensor is also disclosed.

Abstract: Compositions comprising meta-benzylic compounds are prepared. The compositions are useful as antibacterial and as other pharmaceutical agents and as intermediates for preparation of other pharmaceutical agents. In addition, compositions of the present invention are useful as research reagents.

Abstract: Improved methods of detecting and/or treating lesions in a patient are provided.

Abstract: A method for manufacturing an array of thin film actuated mirrors capable of ensuring an optimum optical efficiency is disclosed. The method includes the steps of: forming a thin film sacrificial layer on top of an active matrix; forming an array of semifinished actuating structures on top of the thin film sacrificial layer, wherein each of the semifinished actuating structures includes a thin film electrodisplacive member, a second thin film electrode and an elastic member; forming selectively a polymer layer; depositing a first thin film layer on top of each of the semifinished actuating structures; removing the polymer layer, thereby forming an array of actuating structures, each of the actuating structures having a first thin film electrode and the semifinished actuating structure; and removing the thin film sacrificial layer, thereby forming the array of thin film actuated mirrors.

Abstract: A support material for solid phase synthesis is provided having an amine-containing organic group attached to it through a linker.

Abstract: An apparatus for maintaining the sterilization of a reactor vessel output. The apparatus comprises a connect means for connecting to and enclosing the reactor vessel output and a steam trap means for maintaining steam pressure. The steam trap means is in fluid communication with and downstream from both the connect means and an output means for releasing pressure. The output means is in fluid communication with and downstream from the connect means and the output means is upstream from the steam trap means. This apparatus provides a significant improvement to the fermentation industry by facilitating the maintenance of a sanitized sampling output.

Abstract: An assay for measuring activation (i.e., autophosphorylation) of a tyrosine kinase receptor of interest is disclosed.(a) A first solid phase is coated with a substantially homogeneous population of cells so that the cells adhere to the first solid phase. The cells have either an endogenous tyrosine kinase receptor or have been transformed with DNA encoding a receptor or "receptor construct" and the DNA has been expressed so that the receptor or receptor construct is presented in the cell membranes of the cells.(b) A ligand is then added to the solid phase having the adhering cells, such that the tyrosine kinase receptor is exposed to the ligand.(c) Following exposure to the ligand, the adherent cells are solubilized, thereby releasing cell lysate.(d) A second solid phase is coated with a capture agent which binds specifically to the tyrosine kinase receptor, or, in the case of a receptor construct, to the flag polypeptide.

Abstract: A permeable, liquid flow control material composed of: 1) a permeable sheet having a plurality of individual exposed surfaces, at least a portion of which have a surface energy of less than about 45 dynes/cm; and 2) amphiphilic proteins adsorbed onto at least some individual exposed surfaces to define a gradient distribution of amphiphilic protein coating along at least one dimension of the permeable sheet so that the adsorbed amphiphilic protein coating provides controlled wettability along at least one dimension of the liquid flow control material. Desirably, the liquid flow control material is substantially free of fugitive amphiphilic proteins. The material may be used as a permeable, bodyside cover material for absorbent personal care products.

Abstract: Substantially non-antigenic polymers containing pI and/or pH optimum modulating moieties are disclosed. The polymers are useful as intermediates for synthesis of amine-based polymers and in the formation of activated polymers for conjugation with nucleophiles. Conjugates and methods of preparation and treatment with the conjugates are also disclosed.

Abstract: An oxygen concentration sensor having excellent sealing performance between a lead wire and a lead wire insertion hole includes a sensor element disposed insertedly into a housing, protective covers disposed at an end portion of the housing, lead wires inserted into the protective covers, and an elastic insulating member disposed inside the protective covers and having a lead wire insertion hole for inserting the lead wires. The lead wire insertion hole in the elastic insulating member has a rib protruding in the radial direction. The elastic insulating member is caulked and fixed by the protective covers.

Abstract: A system for handling a body specimen is described for particular use in the handling of fecal specimen which are to be treated with a stain for enhancing its visibility. The system includes dual optical viewing chambers mounted alongside of each other on a frame with appropriate tubing connecting ports of the viewing chambers to a liquid specimen supply and the satin supply. The stain supply is connected to one of the tubings leading to a viewing chamber so that the drawing action from a pump connected to ports on the other side of the viewing chambers can force an automatic mixing of the staining solution with one of the liquid specimen being drawn into one of the viewing chambers. Controls and techniques for operating the system are described.

Abstract: A process for producing composite materials which can be thermally postformed, with a matrix of polylactam produced by means of activated anionic polymerization is offered.

Abstract: Predetermined combinatorial libraries of non-peptide compounds are disclosed. Compounds useful for generating such libraries are also disclosed.

Abstract: An assay for measuring activation (i.e., autophosphorylation) of a tyrosine kinase receptor of interest is disclosed.(a) A first solid phase is coated with a substantially homogeneous population of cells so that the cells adhere to the first solid phase. The cells have either an endogenous tyrosine kinase receptor or have been transformed with DNA encoding a receptor or "receptor construct" and the DNA has been expressed so that the receptor or receptor construct is presented in the cell membranes of the cells.(b) A ligand is then added to the solid phase having the adhering cells, such that the tyrosine kinase receptor is exposed to the ligand.(c) Following exposure to the ligand, the adherent cells are solubilized, thereby releasing cell lysate.(d) A second solid phase is coated with a capture agent which binds specifically to the tyrosine kinase receptor, or, in the case of a receptor construct, to the flag polypeptide.