Patents Examined by Patricia C. Mallari
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Patent number: 7582059Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.Type: GrantFiled: September 6, 2007Date of Patent: September 1, 2009Assignee: Abbott Diabetes Care Inc.Inventors: Jeffery V. Funderburk, Duane O. Yamasaki, Brian VanHiel, Stephen J. Flynn, Bradley D. Kelemen
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Patent number: 7578793Abstract: A method for diagnosis of a sleep-related condition of a patient having a thorax. The method includes receiving physiological signals from sensors coupled to the thorax of the patient, and analyzing the physiological signals, independently of any electroencephalogram (EEG) or electro-oculogram (EOG) signals, in order to identify sleep stages of the patient.Type: GrantFiled: November 22, 2004Date of Patent: August 25, 2009Assignee: Widemed Ltd.Inventors: Koby Todros, Amir Geva, Daniel Reisfeld
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Patent number: 7575553Abstract: Sensing physiological conditions using the sensors of a respiratory therapy device can be used to assess a presence of pulmonary diseases other than breathing rhythm disorders. Non-rhythm related pulmonary diseases include, for example, obstructive pulmonary diseases, restrictive pulmonary diseases, and infectious diseases. Various pulmonary diseases will produce changes in respiratory pressure, airflow, and/or other patient conditions, facilitating assessment of a presence of disease.Type: GrantFiled: August 31, 2004Date of Patent: August 18, 2009Assignee: Cardiac Pacemakers, Inc.Inventors: Jeffrey E. Stahmann, Jesse W. Hartley, Kent Lee, Quan Ni
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Patent number: 7575549Abstract: A device for increasing, monitoring, and measuring perspiration water and solid loss at reduced ambient pressure, comprising a sealed chamber capable of maintaining less than atmospheric pressure for an extended period of time and a gasket-sealed door accessing the chamber. The chamber provides a controlled hypobaric environment for treatment of various medical conditions. Internal controls of ambient pressure inside, temperature, humidity, oxygen, CO2 and other environmental conditions within the chamber are included, as well as a mechanism for recovering perspiration water loss from an occupant of the chamber. Methods for determining the perspiration volume of water and solid loss experienced by an occupant in the chamber are also disclosed including a computer program for determining quantity of sweat produced by the occupant of the chamber on a continuous basis. An algorithm allowing for continuous calculations of sweat loss and fluid replacement requirements of the occupant of the chamber is disclosed.Type: GrantFiled: July 30, 2004Date of Patent: August 18, 2009Inventor: Sherwin Uda Miller
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Patent number: 7574255Abstract: An exemplary method includes providing information (e.g., a left atrial pressure, a NYHA class, echocardiographic information, etc.), based at least in part on the information, determining a weight and, based at least in part on the weight, determining a threshold for use in intrathoracic impedance monitoring. Such an exemplary method may include comparing an intrathoracic impedance to the threshold, comparing an intrathoracic impedance change to the threshold, or comparing a product of intrathoracic impedance and time to the threshold. Various exemplary methods, devices, systems, etc., are disclosed.Type: GrantFiled: November 7, 2005Date of Patent: August 11, 2009Assignee: Pacesetter, Inc.Inventor: Xiaoyi Min
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Patent number: 7566303Abstract: An indicator for characterizing human skin condition includes a flowable carrier, suitable for application to human skin, and at least one dye soluble with oil found on human skin and visually changeable when in solution with oil on human skin. A visual change in the at least one dye is proportional to the amount of the oil present in solution, whereby when the indicator is applied to an area of human skin, and the at least one dye contacts and reacts with the oil in the area, the indicator will display a visual indication of the skin condition in the area based on the amount of the oil in the area.Type: GrantFiled: October 5, 2007Date of Patent: July 28, 2009Assignee: Chameleon Development LLCInventors: J. Dirk Vermeulen, John D. Vermeulen, William Dommer
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Patent number: 7553281Abstract: A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.Type: GrantFiled: October 5, 2007Date of Patent: June 30, 2009Assignees: Roche Diagnostices Operations, Inc., Disetronic Licensing AGInventors: Robert Hellwig, Stefan Weinert
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Patent number: 7544168Abstract: The present invention relates to cuff-based method for the measurement of systolic blood pressure (SBP) by measuring photoplethysmographic (PPG) signals in peripheral blood vessels distal to the cuff and to a method for cuffless measurement of SBP by analyzing PPG signals in peripheral blood vessels, after suitable calibration by the cuff-based PPG method for the measurement of SBP.Type: GrantFiled: September 30, 2004Date of Patent: June 9, 2009Assignee: Jerusalem College of TechnologyInventor: Meir Nitzan
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Patent number: 7524290Abstract: A system and method for taking non-invasive blood pressure and other vascular parameter measurements includes placing a vascular compression device about an appendage of a subject. An arterial/venous occlusion cuff is placed about a base of the appendage. The vascular compression device is activated to generate compression ischemia in the appendage. The arterial/venous occlusion cuff is pressurized to generate arterial/venous occlusion in the appendage. The vascular compression device is deactivated. The arterial/venous occlusion cuff is gradually depressurized to allow blood and other body fluids to flow into the appendage and thereupon determine vascular parameters such as, for example, systolic arterial blood pressure, diastolic arterial blood pressure, venous blood pressure, arterial blood flow, blood vessel compliance, and appendage blood volume.Type: GrantFiled: April 24, 2006Date of Patent: April 28, 2009Assignee: The Kent Scientific CorporationInventor: Andrew H. Ide
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Patent number: 7526327Abstract: There is disclosed a portable instrument including an optical device (4; 5; 6) for measuring a physiological quantity, particularly the heart rhythm, and data emission and/or reception means, the optical device including at least one light source (41; 51; 61) for subjecting a portion of an organic tissue (10) to a light emission and at least one photoreceptor (42; 52, 53, 54; 62, 64, 66) for detecting the intensity of the light emission after propagation in the organic tissue. The optical device also forms the data emission and/or reception means, said at least one light source and/or said at least one photoreceptor being arranged for respectively emitting data to an external unit or receiving data from said external unit.Type: GrantFiled: June 4, 2004Date of Patent: April 28, 2009Assignee: ETA SA Manufacture Horlogère SuisseInventors: Fabien Blondeau, Nakis Karapatis
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Patent number: 7520860Abstract: The disclosure describes an electronic stethoscope system that automatically detects coronary artery disease in patients. The system uses an electronic stethoscope to record acoustic data from the fourth left intercostal space of a patient. A processing technique is then applied in order to filter the data and produce Fast Fourier Transform (FFT) data of magnitude versus frequency. If a bell curve is identified in the data between a predefined frequency range (e.g., 50 and 80 Hz) with a peak magnitude of greater than a predefined threshold (e.g., 2.5 units), the system automatically provides an output indicating that the patient is likely to have 50 to 99 percent stenosis of the coronary artery. If no bell curve is present, the patient may have artery stenosis of less than 50 percent. An interface module may be used to transfer diagnosis information to the stethoscope and data to a general purpose computer.Type: GrantFiled: April 12, 2006Date of Patent: April 21, 2009Inventors: Marie A. Guion-Johnson, Kozhuvattasseril P. Madhusoodanan
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Patent number: 7510533Abstract: A pressure sensing catheter having a pressure sensor and an antenna that is coupled to the pressure sensor, e.g., by a connector, are provided. The pressure sensor can be adapted to measure a pressure surrounding the catheter, and the antenna can be adapted to telemetrically communicate the measured pressure to an external device. In an exemplary embodiment, the antenna, pressure sensor, and/or connector are hermetically sealed, e.g., by the catheter and/or a coating, to prevent the antenna, pressure sensor, and connector from coming into contact with fluid, thereby allowing the catheter to be permanently implanted or otherwise used for long term use. Exemplary methods for manufacturing and using pressure sensing catheters are also provided.Type: GrantFiled: April 11, 2005Date of Patent: March 31, 2009Assignee: Codman & Shurtleff, Inc.Inventors: Christophe Mauge, Alan J. Dextradeur, Daniel J. McCusker, Stefan Meyer, Volker Boedecker, Robert G. Kraus, Max G. Ostermeier
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Patent number: 7510530Abstract: A pressing cuff presses a pressure sensor above an artery. The level of the pressure applied to the pressure sensor is changed while the pulse wave is measured based on information about the pressure from the pressure sensor. In order to adjust the level of the applied pressure using the pressure of gas in the pressing cuff, a three-port valve and a two-port valve are controlled so that the connection is changed to establish a state of holding the amount of the gas in the pressing cuff. Then, the state is changed to a state of isolating and discharging gas in which a part of the held gas is isolated from the remaining amount of the gas to be discharged. Then, the state is changed to the state of holding the remaining amount of gas in the pressing cuff.Type: GrantFiled: September 23, 2004Date of Patent: March 31, 2009Assignee: Omron Healthcare Co., Ltd.Inventors: Masao Hashimoto, Kazuhisa Tanabe, Hironori Satoh, Takashi Inagaki, Ryo Fukui
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Patent number: 7503897Abstract: The preferred embodiment of the present invention comprises a single microprocessor-based interface that connects between a noninvasive blood pressure (NIBP) sensor and an invasive blood pressure (IBP) monitor or module. The interface effectively emulates an IBP transducer in such a way that the IBP monitor sees the interface as if it were a regular IBP transducer from a fluid-filled blood pressure monitoring line. It receives the signal from an NIBP sensor and determines the blood pressure corresponding to the signal. It accepts the excitation voltage provided by the IBP monitor. From the excitation voltage and a known transducer sensitivity which the IBP monitor is configured to work with, the interface emulates the IBP transducer output signal corresponding to the blood pressure. The interface also emulates the input and output impedances of the IBP transducer which the IBP monitor is configured to work with.Type: GrantFiled: November 16, 2006Date of Patent: March 17, 2009Assignee: Healthstats International Pte LtdInventors: Kim-Gau Ng, Wee Leng Peh
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Patent number: 7500949Abstract: A multilumen catheter having tubings extending into lumens within the catheter. The lumens may be used for blood, drugs or other medicants. The lumens may also be used for sensors. The junction element, external to the patient, connects the tubings to the lumens. The tubings, also external to the patient, connect to infusion members, to which one or more infusion systems may be connected to deliver blood, drugs and other medicants to the patient. A sensor having a sensing element may extend through the sensor lumen and be positioned internal to the patient for physiological parameter sensing. An external portion of the sensor may be connected to associated electronics to provide automatic monitoring of the physiological parameters and automatic delivery and control of the infusants.Type: GrantFiled: December 30, 2002Date of Patent: March 10, 2009Assignee: Medtronic Minimed, Inc.Inventors: Rebecca Gottlieb, Rajiv Shah, Mary M. Morris, Victor Giron, Michael E. Miller, Bradley J. Enegren
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Patent number: 7497827Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.Type: GrantFiled: March 10, 2005Date of Patent: March 3, 2009Assignee: DexCom, Inc.Inventors: Mark Brister, Paul V. Neale, James Patrick Thrower, Daniel S. Kline, Daniel Shawn Codd, Sean Saint, Steve Masterson
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Patent number: 7494465Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.Type: GrantFiled: June 21, 2005Date of Patent: February 24, 2009Assignee: DexCom, Inc.Inventors: Mark Brister, Daniel Kline, Steve Masterson, Sean Saint
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Patent number: 7489964Abstract: A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.Type: GrantFiled: November 29, 2006Date of Patent: February 10, 2009Assignee: CNS Response, Inc.Inventors: Stephen C. Suffin, W. Hamlin Emory, Leonard J. Brandt
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Patent number: 7465276Abstract: Methods are disclosed for distinguishing whether an animal is experiencing a bacterial infection or a viral infection. One monitors breath taken from the animal over time to measure the relative amount of a first breath stable isotope to a second breath stable isotope therein over time. A quick change in the isotope ratios within several hours from the likely infection is indicative of a bacterial infection. A delayed change in the isotope ratios, followed by periodic repeated alterations in the ratios, is indicative of viral infection. The methods are particularly efficient when using cavity ringdown spectroscopy for the monitoring. They may be used for monitoring a patient already admitted to a hospital, or for monitoring a patient initially complaining of adverse symptoms, or for triage, or for collectively monitoring a population of animals.Type: GrantFiled: November 30, 2005Date of Patent: December 16, 2008Assignee: Wisconsin Alumni Research FoundationInventors: Fariba M. Assadi-Porter, Mark E. Cook, Warren P. Porter, Daniel E. Butz
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Patent number: 7433727Abstract: The invention consists of a sensor with multiple indicating (sensing) electrodes covered with a selectively permeable membrane for monitoring fluid concentrations in a biological environment. The indicating electrodes respond to changes in certain analytes, such as glucose, through an enzyme-mediated reaction. The currents generated from the enzyme-mediated reactions are transmitted through radio signals to an external receiver where the information is processed and recorded. Through the use of various biomaterials and biochemicals associated with the sensor, the monitoring accuracy is improved and the overall viability is prolonged. The process of foreign body fibrosis (formation of a scar capsule around the implanted sensor) eventually limits the functional life of the device. We teach methods of delivery of certain biochemicals that can increase the functional life of the sensor by inhibiting the formation of the foreign body capsule or by stimulating the growth of capillaries into the capsule.Type: GrantFiled: September 24, 2004Date of Patent: October 7, 2008Assignee: Legacy Good Samaritan Hospital and Medical CenterInventors: W. Kenneth Ward, Michael D. Wood