Patents Examined by R. J. Gallagher
  • Patent number: 3953455
    Abstract: Novel bis basic esters of 9-substituted phenanthrene and related 9-oxa and 9-aza derivatives thereof, their preparation and use for the prevention and inhibition of viral infections are disclosed.
    Type: Grant
    Filed: September 13, 1974
    Date of Patent: April 27, 1976
    Assignee: Richardson-Merrell Inc.
    Inventors: Donald R. Meyer, Arthur D. Sill
  • Patent number: 3951982
    Abstract: Trialkylsilyl esters of 6-(substituted amino)phenyl-1,2-dihydro-2-oxonicotinic acid and acid addition salts thereof are disclosed. The compounds are useful intermediates in the preparation of pharmacological agents, especially antimicrobials of the penicillin or cephalosporin type. The compounds can be produced by reacting a 6-(substituted amino)phenyl-1,2-dihydro-2-oxonicotinic acid with a silylating agent and are converted to the useful corresponding acid chloride by reaction with thionyl chloride.
    Type: Grant
    Filed: November 21, 1974
    Date of Patent: April 20, 1976
    Assignee: Parke, Davis & Company
    Inventor: Om P. Goel
  • Patent number: 3951952
    Abstract: 6-[.alpha.-(Amidino- and imidoylaminoalkanoylamino)aracylamino]-penicillanic acids and synthetic methods for the preparation thereof.
    Type: Grant
    Filed: December 14, 1973
    Date of Patent: April 20, 1976
    Assignee: Pfizer Inc.
    Inventors: Ernest S. Hamanaka, John G. Stam
  • Patent number: 3951986
    Abstract: 2-Propanol derivatives of the formula: ##SPC1##And their pharmaceutically acceptable acid addition salts, which are useful as medicaments and can be produced by reacting a compound of the formula: A-CH.sub.2 -Z with a compound of the formula: A'-H [wherein R is hydrogen or lower alkanoyl; R.sub.1 is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; W is oxygen, sulfur, sulfinyl or sulfonyl; Y is a group of either one of the formulae: ##SPC2##(wherein R.sub.2 is hydrogen, halogen, lower alkyl or lower alkoxy and R.sub.3 is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl); A and A' are each a group of either one of the formulae: ##SPC3##(wherein R.sub.1, W and Y are each as defined above), provided that A and A' are different each other; and Z is a group of either one of the formulae: ##EQU1## (wherein X is halogen, alkylsulfonyloxy or arylsulfonyloxy and R is as defined above)].
    Type: Grant
    Filed: June 18, 1973
    Date of Patent: April 20, 1976
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Isamu Maruyama, Masaru Nakao, Kikuo Sasajima, Shigeho Inaba, Hisao Yamamoto
  • Patent number: 3950334
    Abstract: O-alkyl-S-alkyl-O[6-alkyl- or 6-halo-pyridazin-(3)-yl]-(thiono)thiolphosphoric acid esters of the formula ##SPC1##In whichR and R', which may be identical or different, are each alkyl with 1 to 4 carbon atoms,R" is alkyl with 1 to 3 carbon atoms or halogen, andX is oxygen or sulfur,Which possess insecticidal and acaricidal properties.
    Type: Grant
    Filed: November 11, 1974
    Date of Patent: April 13, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Jochem Riebel, Lothar Rohe, Ingeborg Hammann, Wolfgang Behrenz
  • Patent number: 3948926
    Abstract: A compound represented by the formula ##SPC1##WhereinR, r.sub.1 and R.sub.2 are lower alkyl having six or less carbon atoms;X is halogen.
    Type: Grant
    Filed: October 10, 1974
    Date of Patent: April 6, 1976
    Inventors: Saburo Kano, Osami Nomura, Mitsuo Asada, Meiki Ando, Michihiko Matsuda, Tomio Yamada, Hitoshi Watanabe, Takuzo Taniguchi
  • Patent number: 3948925
    Abstract: Novel compounds of the formula ##EQU1## wherein X is selected from the group consisting of oxygen and sulfur, X.sub.1 is selected from the group consisting of alkyl of 1 to 6 carbon atoms, cyano and ##EQU2## Y.sub.1 is selected from the group consisting of alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms and amino, n is 0, 1 or 2, X.sub.2 is selected from the group consisting of hydrogen, chlorine, bromine, alkyl of 1 to 6 carbon atoms, cyano and ##EQU3## R is alkyl of 1 to 6 carbon atoms, R.sub.1 is selected from the group consisting of alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms and ##EQU4## and R.sub.2 and R.sub.3 are selected from the group consisting of hydrogen and alkyl of 1 to 6 carbon atoms with the proviso that X.sub.1 is other than alkyl when X.sub.2 is alkyl or hydrogen, having insecticidal, nematocidal and acaricidal properties.
    Type: Grant
    Filed: October 17, 1974
    Date of Patent: April 6, 1976
    Assignee: Roussel-UCLAF
    Inventors: Jacques Perronnet, Laurent Taliani
  • Patent number: 3946046
    Abstract: Process for resolving a racemic mixture of an oxo-type prostaglandin intermediate by (a) converting the oxo compound by reaction with an optically active ephedrine to a mixture of oxazolidine diastereomers, (b) separating at least one oxazolidine diastereomer from said mixture, (c) hydrolyzing said oxazolidine to free the optically active oxo compound, and (d) recovering said optically active oxo compound.
    Type: Grant
    Filed: December 15, 1972
    Date of Patent: March 23, 1976
    Assignee: The Upjohn Company
    Inventor: Robert C. Kelly