Patents Examined by Randall Winston
  • Patent number: 10905724
    Abstract: A method for decreasing proliferation of cancer cells comprises the steps of administering a sensitizer. Sensitizers can include selenium, fish oil, and a combination of selenium and fish oil to a cancer cell. The method contemplates that the selenium and fish oil are administered in an amount effective to respectively increase the sensitivity of the cancer cells, and the administration of the combination of selenium and fish oil are administered in an amount effective to synergistically increase the sensitivity of the cancer cells more than the selenium or the fish oil alone. The method additionally exposes cancer cells to temperatures in excess of 37° C.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: February 2, 2021
    Inventor: Houn Simon Hsia
  • Patent number: 10857195
    Abstract: Extracts of plants of the Lamiaceae family, including the Mentha genus, are shown to have a positive impact on overall cognitive health, including improvements in memory, reasoning, attention/concentration, planning, mood, sleep and associated behaviors.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: December 8, 2020
    Assignee: KEMIN INDUSTRIES, INC.
    Inventors: Michael Ceddia, Kelli Herrlinger, Brandon Lewis, Shulin Feng, Kristin Nieman
  • Patent number: 10842841
    Abstract: Improved compositions of reversible monoamine oxidase inhibitors are obtained by improved methods of alcohol removal from distillates of fermented agave extracts.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: November 24, 2020
    Assignee: Roar Holding LLC
    Inventor: Robert W. Brocia
  • Patent number: 10813910
    Abstract: The present invention discloses an herbal anti-AMD composition for treatment of age related macular diseases (AMD). More specifically, the present invention relates to an herbal composition for the prevention, management and treatment of neo-vascular or wet AMD.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: October 27, 2020
    Assignee: Vivek Anand Parachur
    Inventor: Vivek Anand Parachur
  • Patent number: 10813915
    Abstract: The present invention relates to the use of an Angiotensin II type 1 (AT1) receptor blocker for promoting sleep and/or the treatment of insomnia. It is based, at least in part, on the results of experiments performed using a validated rat model of stress-induced insomnia in which candesartan was found to ameliorate sleep disturbances induced by stress. Further, it was observed that this effect seems to be caused by blockade of AT1 receptors located in several brain regions that are key components of the neural circuitry activated during insomnia. In contrast to currently marketed treatments for insomnia, the AT1 receptor blocker was found to restore normal sleep without inhibiting REM sleep and/or inducing atypical wave components in the EEG.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: October 27, 2020
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Georgina Cano, Alan F. Sved
  • Patent number: 10799544
    Abstract: The present invention relates to a feed supplement which comprises a resin acid based composition comprising over 10% (w/w) resin acids for use in the prevention of growth of harmful bacteria in the animal digestive tract, in the prevention of intestinal disorders, in the modulation of microbial population of the animal digestive tract, in enhancing rumen fermentation, lowering rumen methane production and/or in binding toxins. The invention further relates to a use of the feed supplement and a feed composition comprising the feed supplement.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: October 13, 2020
    Assignees: Hankkija Oy, Forchem Oy
    Inventors: Mikko Rintola, Juha Orte, Juhani Vuorenmaa, Hannele Kettunen
  • Patent number: 10772925
    Abstract: The present invention relates to a composition comprising a dry preparation of Alpinia galanga (L.) Willd (Zingiberaceae) or Alpinia conchigera Griff and a plant extract comprising compounds with anti-oxidative activity, such as an extract of Punica granatum. Also disclosed herein is a method of improving semen quality by administering said composition to a male subject in need thereof.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: September 15, 2020
    Assignee: NERTHUS APS
    Inventors: Ina Giversen, Henrik Jakobsen
  • Patent number: 10765621
    Abstract: New extracts are suggested of Halimione portulacoides or sea purslane, and related species of Halimione, obtainable by treating the said plant with a solvent selected from the group consisting of C1-C4 aliphatic alcohols, ethyl acetate, water or their mixtures, removing the dissolved extracts from the residues and recovering the pure extracts from the solvent. The extracts show excellent properties particularly in modulating the metabolism of human skin and hair follicles.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: September 8, 2020
    Assignee: Symrise AG
    Inventors: Lorenzo Zanella, Paolo Pertile
  • Patent number: 10736929
    Abstract: The present invention relates to a method for preparing an herbal composition with increased fat-soluble polyphenols, an herbal composition prepared by the method, and a use of the composition. The herbal composition with increased fat-soluble polyphenols of the present invention is characterized by the significantly increased content of fat-soluble polyphenols including decursin, compared with the herbal composition of comparative example, and also demonstrates a significant anti-oxidative activity, immune cell activating effect, and cancer cell growth inhibitory effect, significantly reduces renal toxicity and liver toxicity induced by the anticancer agent cisplatin back so as to be almost normal condition, and significantly inhibits the intestinal crypt loss caused by irradiation, compared with the herbal composition of comparative example.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: August 11, 2020
    Assignee: KOREA ATOMIC ENERGY RESEARCH INSTITUTE
    Inventors: Sung-Kee Jo, Hae Ran Park, Uhee Jung, Ho Yong Lee, Hyang Hee Cho
  • Patent number: 10729737
    Abstract: The objective of the present invention is to provide a safe muscle-enhancing agent by which a muscle mass and muscular strength can be effectively increased or maintained and by which a decrease of a muscle mass and muscular strength can be suppressed, a muscle-enhancing composition containing the muscle-enhancing agent, and a method for enhancing muscle by using the muscle-enhancing agent or muscle-enhancing composition. The muscle-enhancing agent according to the present invention is characterized in comprising an extract derived from lemon myrtle as an active ingredient.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: August 4, 2020
    Assignee: KANEKA CORPORATION
    Inventors: Shinichi Honda, Shinichi Yokota, Mineko Ogura, Masanori Kato
  • Patent number: 10716821
    Abstract: The present invention provides a method of using a plant extract or active fraction thereof for inhibiting an herpes simplex virus (HSV) infection, wherein the plant is a: Cornus species; Achillea species; Trifolium species; Trillium species; and/or Plantago species. The present invention also provides plant extracts, active fractions, and compositions kits comprising same.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: July 21, 2020
    Assignee: UNIVERSITÉ DU QUÉBEC A CHICOUTIMI
    Inventors: Jean Legault, André Pichette, Isabelle Côté, Serge Lavoie
  • Patent number: 10709748
    Abstract: Preparation of cannabinoid formulations containing: ?9-tetrahydrocannabinol (?9-THC), ?8-tetrahydrocannabinol (?8-THC), ?9-tetrahydrocannabinolic acid (THCa), cannabidiol (CBD), cannabidiolic acid (CBDa), cannabigerol (CBG), cannabichromene (CBC) and cannabinol (CBN), either alone or in combinations henceforth known as cannabis, have been created using an emulsification process to encapsulate cannabinoids. The aqueous-based method involves micellular encapsulation of cannabinoids, a method that has been used to increase the bioavailability of poorly permeable, lipophilic drugs. The present invention demonstrates the viability of transdermal delivery with gels and patches for consistent and sustained cannabinoid dosing.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: July 14, 2020
    Assignee: NUTRAE, LLC
    Inventors: Christopher G. Witowski, Jacqueline L. Salm
  • Patent number: 10702492
    Abstract: The invention provides a novel PPAR? activator, a pharmaceutical composition, a food or a drink, a food additive, a supplement and a method of producing these products. The PPAR? activator includes an extract of a koji that contains 9-hydroxy-10,12-octadecadienoic acid (9-HODE: 10E, 12E) or an active fraction of the extract, as an active ingredient.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: July 7, 2020
    Assignee: Marukome Co., Ltd.
    Inventors: Teruo Kawada, Tsuyoshi Goto, Haruya Takahashi, Hsin-Yi Chi, Noriyoshi Ichijo, Keiji Nakata
  • Patent number: 10695283
    Abstract: This invention relates to the isolation, and use of a plant extract in the treatment of skin hyper-pigmentation. More particularly, this invention relates to the isolation of a tyrosinase inhibitor in an extract of plant matehal from the Greyia radlkoferi (G. radlkoferi) plant, the extract including 5,7-dihidroxyflavone[(2S)-pinocembrin]; 2?,6?-dihydroxy-4?-methoxydihydrochalcone; 2?,4?,6?-trihydroxyhydrochalcone; 3,5,7-trihydroxyflavone and 4?,5?7-thhydroxyisoflavone.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: June 30, 2020
    Assignees: UNIVERSITY OF PRETORIA, UNIVERSITY OF KWAZULU-NATAL
    Inventors: Marco Nuno De Canha, Namrita Lall, Ahmed Hussein, Elizabeth Mogapi, Indres Moodley
  • Patent number: 10694761
    Abstract: The invention provides a novel chocolate mass which has a glycemic index of less than 29 (GI<29) and of which the content of added sugar comprises at least 10% galactose and in addition a content of iosmaltulose and/or tagatose. The chocolate mass additionally has a content of vitamin E in the form of a tocotrienol-tocopherol mixture from natural sources, wherein the content of tocotrienols in the chocolate mass is greater than the content of tocopherols.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: June 30, 2020
    Inventor: Johannes Coy
  • Patent number: 10695388
    Abstract: Approach is provided for a high molecular weight polymeric composition and a new usage of the high-molecular weight polymeric composition. The new usage of the high-molecular weight polymeric composition directly adsorbs body fluid, or indirectly adsorbs toxin or stimulating substance existed in the intaked solution or liquid and removes the body fluid or the toxin or stimulating substance out of body. Therefore, the high-molecular weight polymeric composition is helpful to reduce the food digestibility or to prevent the toxin or stimulating substance from adsorbing in the gastrointestinal tract, even to bring the toxin or stimulating substance out of the body. Accordingly, the high-molecular weight polymeric composition is able to be applied to control weight by lowering the food digestibility or avoid damage by decreasing the toxin or stimulating substance released into the body. The high molecular weight polymeric composition has well biocompatibility to be widely applied in human.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: June 30, 2020
    Inventor: Shao Chi Hsin
  • Patent number: 10688144
    Abstract: Provided are a pharmaceutical composition for preventing and/or treating osteoarthritis comprising an extract of Angelica gigas Nakai, a pharmaceutical composition for preventing and/or treating osteoarthritis comprising a mixed extract of Angelica gigas Nakai and Cnidium officinale, and a method of preventing and/or treating osteoarthritis comprising administering the extract of Angelica gigas Nakai or the mixed extract of Angelica gigas Nakai and Cnidium officinale.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: June 23, 2020
    Inventor: Kang Hyun Lee
  • Patent number: 10675228
    Abstract: The present invention relates to a skin massage gel which does not cause skin irritation because it does not contain dark brown sugar crystals and which can be safely used because it includes only natural materials, and a method of preparing the same. The method includes the steps of: (1) adding 8-12 parts by weight of malt powder made from dehusked malt to 100 parts by weight of rice wine, followed by heating while stirring in one direction; (2) filtering the heated solution using a filter; (3) adding 80-120 parts by weight of dark brown sugar to the filtered solution, followed by heating while stirring; (4) adding 25-35 parts by weight of honey to the solution, followed by heating; (5) adding 0.004-0.006 parts by weight of gold powder to the solution, followed by heating; and (6) aging the solution at room temperature.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: June 9, 2020
    Inventors: Guk Hee Lee, Geon Guk Han
  • Patent number: 10675317
    Abstract: The invention discloses new application of a ginseng extract, ginsenoside and a ginsenoside derivative in the preparation of a medicine for treating HCMV infection related diseases. The related diseases comprise HCMV infection caused in the process of treating cardiovascular and cerebrovascular diseases, organ transplantation, perinatal periods, tumors, burn, AIDS and other diseases of patients. Tests prove that the ginseng extract, the ginsenoside and the ginsenoside derivative have a remarkable curative effect, quick response and a small toxic or side effect during treatment of HCMV infected diseases, are a medicine or a health product for treating the HCMV infection, which is safe, efficient and stable and has a simple preparation process, and are suitable for industrial production and easy to popularize. In the invention, a new medicine source is provided for the treatment of the HCMV infection.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: June 9, 2020
    Inventor: Li Fu
  • Patent number: 10668122
    Abstract: The Toona sinensis extract of the present invention is prepared using supercritical fluid technique, wherein the method includes steps of: (a) drying the leaves of T. sinensis; (b) pulverizing the leaves as particles; and (c) extracting the particles with supercritical carbon dioxide to obtain the T. sinensis extract. This supercritical T. sinensis extract not only can decrease blood sugar level, but also promotes lipid degradation, inhibits the formation of huge lipid droplet and improves the metabolic symptoms. Accordingly, the T. sinensis extract further is able to be prepared as food supplement and pharmaceuticals.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: June 2, 2020
    Assignees: METAL INDUSTRIES RESEARCH & DEVELOPMENT CENTRE, KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Pei-Jung Lien, Chuan-Chia Sun, Tzu-Chen Kuo, Sheng-Chung Yang, Yang-Chang Wu, Fang-Rong Chang, Tusty-Jiuan Hsieh, Yi-Hong Tsai, Ying-Chi Du