Patents Examined by Renee Claytor
  • Rapid antimicrobial susceptibility testing based on a unique spectral intensity ratio analysis via single fluorescence membrane dye staining and flow cytometry
    Patent number: 10995357
    Abstract: Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). This allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections and those that eventually lead to sepsis.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: May 4, 2021
    Inventors: Gal Ingber, Moshe Ben-David, Mushki Fridman, Yael Gluckman, Dina Gohman, Orly Hammer Munz, Anita Shinderman, Eran Zahavy
  • Microbial-based waste water treatment compositions and methods of use thereof
    Patent number: 10988728
    Abstract: The present invention relates to microbial compositions useful in treating and remediating wastewater, removing organic matter from the surfaces of post harvested fruits and vegetables, and decreasing post-harvest disease in fruit and vegetables.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: April 27, 2021
    Assignee: BiOWiSH Technologies, Inc.
    Inventors: Richard Carpenter, Michael S. Showell, JoElla Barnes, Nirupam Pal
  • Synthetic composition for preventing or treating CVD
    Patent number: 10987368
    Abstract: The invention relates to HMOs and compositions comprising thereof for reducing the risk of, preventing, or treating CVD and/or CDV associated pathological conditions or diseases in humans, particularly in overweight and obese humans.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: April 27, 2021
    Assignee: Glycom A/S
    Inventors: Louise Kristine Vigsnæs, Bruce McConnell, Emma Elison
  • Thermoreversible polymers and methods of use thereof
    Patent number: 10982055
    Abstract: The present disclosure provides thermoreversible polymers, hydrogel compositions comprising the thermoreversible polymers, as well as methods of making and using the thermoreversible polymers.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: April 20, 2021
    Assignee: The Regents of the University of California
    Inventors: Christina Marie Fuentes, Barbara L. Ekerdt, David V. Schaffer, Rachel Segalman, Yuguo Lei
  • Culture medium for cellular immunotherapy
    Patent number: 10975353
    Abstract: The present invention provides a method for preparing a cell culture medium comprising a mixture of blood products from two or more donors, comprising the steps of: a) providing at least a first blood product from a first donor; b) measuring the concentration of at least one quality factor in the first blood product; c) comparing the measured concentration of a quality factor to a concentration range predefined for the quality factor; d) selecting the first blood product for the cell culture medium if the concentration measured for the quality factor is in the predefined range and optionally converting the first selected blood product into a first processed blood product or else unselecting the first blood product.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: April 13, 2021
    Assignee: polybiocept GmbH
    Inventors: Jakob Geyer, Markus Maeurer, Ernest Dodoo
  • Stable dry probiotic compositions for special dietary uses
    Patent number: 10953050
    Abstract: A dry stable probiotic composition is provided. The composition comprises one or more viable probiotic microorganisms, one or more hydrolyzed proteins, one or more disaccharides, one or more oligosaccharides, and one or more polysaccharides, but not trehalose. The composition has viability of at least 1×1010 CFU/g, and a viability loss of less than 1 log unit/g after 3 months at a temperature of 40° C. and a relative humidity of 33%. Also provided are methods for preparing the dry stable probiotic composition.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: March 23, 2021
    Assignee: Advanced BioNutrition Corp.
    Inventors: Majid Keshtmand, Mordechai Harel, Trisha Rice
  • Composition comprising bacillus
    Patent number: 10945437
    Abstract: The present invention refers to a composition comprising Bacillus subtilis (DSM 17231) and Bacillus licheniformis (DSM 17236) with nematicidal effect against phytonematodes on plants and/or its habitat, to its use and process for its preparation, use of Bacillus subtilis (DSM 17231) and Bacillus licheniformis (DSM 17236), processes for controlling, combating and conferring specific resistance to phytonematodes, and a kit.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: March 16, 2021
    Assignee: CHR. HANSEN A/S
    Inventors: Abilio Alessandri, Inge Knap, Luciana Sekito De Freitas Zambelli
  • Cancer treatment using beta-(1-3)-(1-4)-glucan
    Patent number: 10946038
    Abstract: A method of treating a subject having cancer is described that includes administering a therapeutically effective amount of a ?-(1,3)-(1,4) glucan to the subject. Methods of immunostimulating in a subject by administering an effective amount of a ?-(1,3)-(1,4) glucan to the subject are also described.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: March 16, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Mei Zhang, Alex Y. Huang, Julian Kim
  • Lactobacillus supplement for alleviating type 1 diabetes
    Patent number: 10925907
    Abstract: Isolated Lactobacillus strains are useful in preventing or delaying the development of Type 1 Diabetes (T1D). A probiotic composition comprising the Lactobacillus strains and use of the composition in T1D prevention are provided.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: February 23, 2021
    Assignee: Universtiy of Florida Research Foundation, Incorporated
    Inventor: Graciela Liliana Lorca
  • Method for engineering three-dimensional synthetic vascular networks through mechanical micromachining and mutable polymer micromolding
    Patent number: 10919183
    Abstract: The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: February 16, 2021
    Assignees: CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation, University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Philip R. LeDuc, O. Burak Ozdoganlar, Mary E. Wilson, Emrullah Korkmaz, Yadong Wang, Donna Beer-Stolz
  • Bovine milk oligosaccharides
    Patent number: 10918653
    Abstract: Oligosaccharides from bovine milk, whey and dairy products, and methods of producing bovine milk oligosaccharides are provided.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: February 16, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: J. Bruce German, David Mills, Carlito B. Lebrilla, Daniela Barile, Riccardo LoCascio
  • Mass-spectrometric resistance determination by growth measurement
    Patent number: 10913968
    Abstract: The invention relates to a mass-spectrometric method to determine microbial resistances to antibiotics, in which the microbes are cultured in a medium comprising an antibiotic, and a mass spectrum of the microbes is acquired after they have been cultured. The method is characterized by the fact that any microbial growth taking place during the culture is mass-spectrometrically determined with the aid of a reference substance, which is added in a dosed amount and is co-measured in the mass spectrum, wherein a growth in microbes indicates the resistance to the antibiotic.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: February 9, 2021
    Inventors: Christoph Lange, Katrin Sparbier
  • Guanidine-functionalized metal silicate particles and methods of making and using such particles
    Patent number: 10914659
    Abstract: Guanidine-functionalized particles and methods of making and using such particles are provided, such as guanidine-functionalized metal silicate particles. A nonwoven article is also provided including a porous fibrous nonwoven matrix and guanidine-functionalized metal silicate particles enmeshed within the porous fibrous nonwoven matrix. The nonwoven article may be used, for instance, for removing microorganisms from an aqueous sample by contacting a fluid sample with the nonwoven article such that at least a portion of the microorganisms are removed from the fluid sample.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: February 9, 2021
    Assignee: 3M Innovative Properties Company
    Inventors: Manjiri T. Kshirsagar, George W. Griesgraber
  • Enzyme formulation and method for degradation
    Patent number: 10907143
    Abstract: An enzyme formulation includes an encapsulated fungal enzyme which is effective for degrading at least one material selected from the group consisting of hydrocarbons, vulcanized rubber, synthetic rubber, natural rubber, vulcanized polymers and perfluorinated compounds. A degradation method includes treating one of the above-mentioned materials with an encapsulated fungal enzyme to degrade the material.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: February 2, 2021
    Assignee: Battelle Memorial Institute
    Inventors: Katarzyna Hanna Kucharzyk, Ramanathan Lalgudi
  • Compositions and methods for cleaning contaminated solids and liquids
    Patent number: 10906075
    Abstract: The present invention relates to compositions and methods for the remediation of contaminated solids and liquids. In particular, embodiments of the present invention relate to the bioremediation of solids and liquids by a composition comprising a biocatalyst or mixture of biocatalysts. The present invention also relates to methods for producing the bioremediation compositions and methods for applying the bioremediation compositions to contaminated sites, including treatment, storage, and disposal facilities, as well as various contaminated water sources, such as aquifers and reservoirs.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: February 2, 2021
    Inventors: Todd Franssen, Carla Franssen
  • Methods for improving proliferation and stemness of limbal stem cells
    Patent number: 10894945
    Abstract: Provided are methods for improving the proliferation and stemness of limbal stem cells (LSCs) by adding a Wnt inhibitor to a medium for limbal explant cultures. When human limbal explants are cultured according to the methods, Wnt/?-catenin signaling is inhibited, resulting in improvement of LSC proliferation, and improvement in the stemness of LSCs, and thus the LSCs may be obtained in high yield.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: January 19, 2021
    Assignee: CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
    Inventors: So-Hyang Chung, Hyun Jung Lee
  • Directed cardiomyocyte differentiation and ventricular specification of stem cells
    Patent number: 10888588
    Abstract: Disclosed is a fully chemically defined, small molecule-mediated, directed differentiation system that promotes differentiation of stem cells, including embryonic stem cells, induced pluripotent stem cells, and adult stem cells, such as human forms of these stem cell types, to ventricular cardiomyocytes in a highly efficient, reproducible and scalable fashion. Also disclosed is a cost-effective and efficient protocol, or method, for generating cardiomyocytes and a cost-effective and efficient method of maturing cardiomyocytes. The disclosed differentiation system provides a platform to perform large-scale pharmacological screenings and to provide a valuable source of each of cardiac progenitor cells and cardiomyocytes for cell replacement therapies in cardiac repair.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: January 12, 2021
    Assignees: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, THE UNIVERSITY OF HONG KONG
    Inventors: Roger Joseph Hajjar, Camie W. Chan
  • Biogeochemical transformations of flue gas desulfurization waste using sulfur oxidizing bacteria
    Patent number: 10882770
    Abstract: In some embodiments, the invention provides a method for converting of a flue gas desulfurization (FGD) waste product to a gypsum-enriched product by fostering growth of sulfur oxidizing bacteria (SOB) in the FGD waste product. Also provided are isolated sulfur oxidizing bacteria cultures as well as kits comprising an isolated sulfur oxidizing bacteria culture and written instructions for fostering the growth of the isolated sulfur oxidizing bacteria culture in FGD waste product to product a gypsum-enriched product.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: January 5, 2021
    Assignee: Geosyntec Consultants, Inc.
    Inventors: Duane Graves, Allison Kreinberg, Robby White, Brianna Wallace, Brian Adair, Linxi Chen, Sarah Marie Herr
  • Method for employing corn plant material comprising cobs in the manufacture of ethanol
    Patent number: 10870867
    Abstract: Ear corn is picked from corn fields by ear corn harvesters and transported to a central shelling station associated with an ethanol manufacturing facility. Shelled corn from the central shelling station is processed into ethanol at the ethanol manufacturing facility, and corn cobs from the central shelling station are burned to provide process heat for the ethanol manufacturing process. Energy is conserved and costs are reduced during the picking and shelling of the ear corn and by the burning of cobs for process heat.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: December 22, 2020
    Inventor: Alvin D. Shulman
  • Use of as a stimulant of plant growth and biological control means, and isolates of said species
    Patent number: 10856551
    Abstract: The invention relates to the use of microorganisms as plant growth stimulants and for the biological control of bacteria, insects, fungi and phytopathogenic nematodes. More specifically, the invention relates to the use of microorganisms of the genus Bacillus, more specifically the Bacillus methylotrophicus species, as well as to cultures thereof, compositions comprising these bacteria, different culture methods and the products comprising same, as plant growth stimulants and for the biological control of bacteria, insects, fungi and phytopathogenic nematodes.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: December 8, 2020
    Assignee: UNIVERSIDAD DE GRANADA
    Inventors: María Victoria Béjar Luque, Inmaculada Llamas Company, Cristina Ruíz García, Emilia Quesada Arroquia