Abstract: Ergolines are chlorinated with SO.sub.2 Cl.sub.2 /BF.sub.3 .multidot.etherate, preferentially in the 2 position.

Abstract: This invention discloses the compound 1-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)-3,4-dimethyl-5-acetyloxy-1,3-i midazolidin-2-one and its use as a herbicide.

Abstract: 2-R-substituted-1,2,5-thiadiazole-3-ones have broad spectrum antibacterial and antifungal activity. They are especially useful in agriculture to protect plants against diseases such as leaf, stem, and fruit spotting, internal discoloration and decay of fruits and vegetables. These compounds are particularly active against diseases caused by the genera Pseudomonas, Xanthomonas, Erwinia, and Corynebacterium.

Abstract: The title compound is a novel substance which effectively treats helminthiasis.

Abstract: Compounds of the structure ##STR1## wherein Y is O, NH or NAc; X is H, .beta.-D-ribofuranosyl or 2,3,5-tri-O-Ac-.beta.-D-ribofuranosyl and Ac is acetyl; are useful as antimicrobal agent.

Abstract: Novel substantially colorless dye precursors represented by the formula ##STR1## WHEREIN R.sup.1 is hydrogen or alkyl; R.sup.2, R.sup.3 and R.sup.5 is alkyl; R.sup.4 is alkyl or phenyl; Z, taken with N, represents the atoms necessary to make a benzthiazole radical; X is an acid anion; and n is 1 when R.sup.5 carries a negative charge and 2 when R.sup.5 is electrically neutral.

Abstract: This invention discloses new compounds of the formula ##STR1## wherein R.sup.1 is selected from the group consisting of alkyl, cycloalkyl, alkenyl, haloalkyl, alkoxy, alkylthio, alkylsulfonyl and alkylsulfinyl; and R.sup.2 is selected from the group consisting of alkyl, alkenyl, alkynyl and haloalkyl.

Abstract: The invention relates to novel 6-aryloxy-2-oxo-1-aza-4-(or thia)-spiro[4,5]decane compounds. These compounds are represented by the formula: ##STR1## in which A stands for an oxygen or sulfur heteroatom; R.sub.1 and R.sub.2 are each H, lower alkyl or aryl such as phenyl; X is H, a halogen atom such as chlorine or fluorine or a lower alkyl.Compounds according to the invention are useful as stimulating agents for vigilance, as psycho-stimulators and genesic stimulators.

Abstract: Insecticidally active compounds are disclosed, defined by the general formula ##STR1## in which R.sup.1 is methoxy, ethoxy, or alkyl having from 1 to 10 carbon atoms;R.sup.2 is alkoxy having from 1 to 10 carbon atoms;R.sup.3 is hydrogen or phenyl; andX is sulfur or oxygen;And intermediates for the preparation of such compounds defined by the general formula ##STR2## IN WHICH R.sup.3 is as defined above.

Abstract: The present invention provides compounds of formula I, ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms in position 1 or 2 of the indazole nucleus,R.sub.2 is hydrogen, halogen, trifluoromethyl, hydroxy or alkyl, alkylthio or alkoxy of 1 to 4 carbon atoms, or a group of formula II, ##STR2## wherein X is oxygen or sulphur,R.sub.3 is hydrogen, halogen, trifluoromethyl, hydroxy or alkyl, alkylthio or alkoxy of 1 to 4 carbon atoms, andR.sub.4 is hydrogen or a group of formula II, as defined above, with the proviso that one of R.sub.2 and R.sub.4 is a group of formula II and the other is other than a group of formula II,useful as myotonolytics and anti-hypertensives.

Abstract: The new compound 2-trichloromethyl-1,3,4-thiadiazole, a process for its manufacture, a fungicide containing this compound as active ingredient, and a process for controlling fungi with this compound.

Abstract: Diuretically active thiazolidine compounds and methods for making the same are disclosed, said compounds having an alkyl or alkenyl substituent in the 1-position, an imino group in the 2-position, and an hydroxy group and an N-acylated 3'-sulfamoylphenyl substituent in the 4-position, i.e.

Abstract: Compounds of the formula ##STR1## wherein A is --CH.dbd.CH--, --CH.dbd.N-- or --S--,R.sub.1 is hydrogen, lower alkyl, lower alkoxy, amino, acetylamino, cyano, tetrazol-5-yl, --COR.sub.3 or a fused benzene ring,Where R.sub.3 is lower alkoxy, amino, hydroxyamino, tetrazol-5-yl-amino or, when R.sub.2 is other than hydrogen, also hydroxyl, andR.sub.2 is cyano, tetrazol-5-yl, --COR.sub.4 or, when R.sub.1 is cyano, tetrazol-5-yl or --COR.sub.3, also hydrogen, lower alkyl, lower alkoxy, amino, acetylamino or a fused benzene ring,Where R.sub.4 is lower alkoxy, amino, hydroxyl, hydroxyamino or tetrazol-5-yl-amino;Non-toxic, pharmacologically acceptable acid addition salts thereof; and, when R.sub.3 and/or R.sub.4 are hydroxyl, non-toxic, pharmacologically acceptable salts thereof formed with an inorganic or organic base. The compounds as well as their salts are useful primarily as antiallergics.

Abstract: Synthesis of penniclavine and of elymoclavine, intermediates useful therein, and novel compounds producible therefrom.

Abstract: Novel substituted nitroimidazoles are provided, for example, 2-(4,5-substituted-isoxazol-3-yl)-1-substituted-5-nitroimidazole; 2-(4,5-disubstituted-.DELTA..sup.2 -isoxazolin-3-yl)-1-substituted-5-nitroimidazole; or 2-(4,5-disubstituted-2-loweralkyl-isoxazolidin-3-yl)-1-substituted-5-nitro imidazole. These compounds have antibacterial and antiprotozoal activity especially against human and animal trypanosomiasis and trichomoniasis.

Abstract: Piperazine compounds of the formula ##STR1## and salts thereof with physiologically tolerable acids useful for the treatment of vascular and cardiac diseases, are disclosed, as are methods for making the compounds and pharmaceutical compositions containing the compounds.

Abstract: Novel acaricidally effective thiazoline compounds corresponding to the general formula ##STR1## wherein R.sub.1 and R.sub.2, independently of one another, represent chlorine, methyl or ethyl, whereby R.sub.2 can occupy the 4- or 6-position, with the exception that if R.sub.1 and R.sub.2 represent chlorine, R.sub.2 cannot be in the 4-position, R.sub.3 represents a straight-chain or branched-chain alkyl group having 1 to 4 carbon atoms, optionally substituted by alkoxy having 1-2 carbon atoms, or a straight-chain or branched-chain alkenyl group having 3 to 5 carbon atoms, optionally substituted by halogen including the acid addition salts, particularly the hydrochlorides, and compositions containing these compounds, as well as the use of these compounds for combatting mites, particularly ticks.

Abstract: A new class of herbicidal compounds consisting of 1-alkyl- and 1,1-dialkyl-3-(4-substituted-3-amino-5-isothiazolyl)ureas and N-(4-substituted-3-amino-5-isothiazolyl)-alkanamides, in which the 4-substituent consists of cyano and carbamoyl, exhibits preemergence and postemergence herbicidal activity, controlling effectively the growth of a wide spectrum of grassy and broad-leaved plant species. The synthesis of members of this class is described in detail, and the utility of representative compounds is exemplified.

Abstract: The compounds are guanidines, for example N-benzenesulphonyl-N'-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidi ne, which are inhibitors of histamine activity.

Abstract: Substituted pyrrole compounds, such as 3-ethyl-4-methyl-5-carbethoxy pyrrole, 2,4-dimethyl-3-acetyl pyrrole and 2-methyl-5-carboxy pyrrole-4-propionic acid diethyl ester, are alkylated in a single step by reaction with an aldehyde or ketone in the presence of both an acid condensing agent such as hydriodic acid and a compatible reducing agent such as metallic zinc or stannous chloride. Suitable carbonyl reactants include formaldehyde, paraldehyde, isobutyraldehyde, acetone, cyclohexanone and methyl-isobutyl ketone.This application is a continuation application of U.S. application Ser. No. 281,624 filed Aug. 18, 1972, now abandoned, which is a continuation-in-part application of U.S. application Ser. No. 832,001, filed June 10, 1969, now abandoned.