Abstract: This invention discloses new compounds of the formula ##STR1## wherein X is selected from the group consisting of alkyl, halogen, haloalkyl and alkoxy; n is an integer from 0 to 2; R.sup.1 is selected from the group consisting of alkyl, alkenyl, haloalkyl and alkynyl; and R.sup.2 is selected from the group consisting of alkyl, alkenyl, haloalkyl, alkynyl, alkoxyalkyl, cycloalkyl and ##STR2## WHEREIN P IS AN INTEGER FROM 0 TO 2; Y is selected from the group consisting of alkyl, alkenyl, halogen, haloalkyl, alkoxy, alkylthio, nitro and cyano; and m is an integer from 0 to 3.

Abstract: Dyes of the formula: ##STR1## in which Z is unsubstituted or substituted alkyl, alkenyl, cycloalkyl, aralkyl, aryl or heteroaryl or a radical of the formula ##STR2## Z.sup.1, Z.sup.2, Z.sup.3 and Z.sup.4 are hydrogen or unsubstituted or substituted alkyl, cycloalkyl, aralkyl or aryl;Z.sup.1 and Z.sup.2 or Z.sup.3 and Z.sup.4 may together with the nitrogen form a heterocyclic ring;Z.sup.1 and Z.sup.2 together with the nitrogen may be a saturated unsubstituted or substituted 5-membered or 6-membered ring condensed on in the ortho-position to the nitrogen;B is unsubstituted or substituted alkyl, alkenyl, cycloalkyl, aralkyl, aryl or heteroaryl; andX is imino or oxygen.The dyes give brilliant yellow dyeings having good fastness properties on textile materials, particularly polyester materials, and in plastics.

Abstract: This invention discloses new compounds of the formula ##STR1## wherein X is selected from the group consisting of alkyl, halogen, haloalkyl and alkoxy; n is an integer from 0 to 2; R.sup.1 is selected from the group consisting of alkyl, alkenyl, haloalkyl and ##STR2## wherein R.sup.4 and R.sup.5 are each selected from the group consisting of hydrogen and alkyl; and R.sup.2 and R.sup.3 are each selected from the group consisting of hydrogen, alkyl, alkenyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, cycloalkyl and ##STR3## WHEREIN P IS THE INTEGER 0 OR 1; Y is selected from the group consisting of alkyl, alkoxy, alkylthio, halogen, haloalkyl, nitro and cyano; and m is an integer from 0 to 3.

Abstract: This invention discloses new compounds of the formula ##STR1## WHEREIN R.sup.1 is selected from the group consisting of alkyl, cycloalkyl, alkenyl, haloalkyl, alkoxy, alkylthio, alkylsulfonyl and alkylsulfinyl; R.sup.2 is selected from the group consisting of alkyl, alkenyl, haloalkyl and ##STR2## wherein R.sup.3 and R.sup.4 are each selected from the group consisting of hydrogen and alkyl; m is an integer from 1 to 3; Y is oxygen or sulfur; X is selected from the group consisting of alkyl, alkenyl, alkoxy, alkylthio, halogen, haloalkyl, nitro and cyano; and n is an integer from 0 to 5. Further disclosed is the herbicidal utility of the foregoing compounds.

Abstract: Non-toxic, pharmaceutically acceptable acid addition salts of a compound of the formula ##STR1## wherein R is an alkyl of 2 to 12 carbon atoms and R' is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms and acyl of an organic carboxylic acid of 1 to 12 carbon atoms having antilipolytic activity and a very prolonged vasodilatatory activity.

Abstract: Thiazolinone analogues of indolmycin having anti-viral activity as well as a degree of antibacterial and antimycoplasmal activity in contrast to the known indolmycin which has only some antibacterial activity. Tautomers and a single enantiomer or mixture of enantiomers are included. Intermediates are described which are cyclized to produce the active antiviral substances. Suitable dosage forms and amounts are set forth and various routes of administration included including administration to the respiratory tract as by insufflation or inhalation.

Abstract: A process for preparing 5-(alkoxy- and aminoethylthio)methylthiazole compounds via displacement of the trisubstituted phosphonium group from 5-(trisubstituted phosphonium)methylthiazole compounds is disclosed.

Abstract: Novel substituted thiazoles of the formula ##STR1## wherein R is alkyl of 1 to 5 carbon atoms and R.sub.1 is selected from the group consisting of --NH.sub.2, -- NH-AlK, ##STR2## PHENYLAMINO AND DIPHENYLAMINO, AlK is alkyl of 1 to 4 carbon atoms and n is an integer from 1 to 6 and their non-toxic, pharmaceutically acceptable acid addition salts having a marked antilipolytic activity and for some of them, a prolonged vasodilatatory activity and an antibradykinetic activity and their preparation.

Abstract: Thiophene analogs of saccharine, i.e., the new compounds 2,3-dihydro-3-oxothieno-[3,4-d]-, -[2,3-d]- and -[3,2-d]-isothiazole-1,1-dioxide, and processes for their manufacture. The new compounds are excellent sweeteners and have no unpleasant taste.

Abstract: Optically and therapeutically active compounds of the formula: ##STR1## wherein R represents a member selected from the group consisting of a straight or branched alkyl group of from one to twenty carbon atoms (C.sub.1 -C.sub.5 being preferred), an ethoxycarbonyl group, a benzyloxycarbonyl group, a phenyl group, an ##STR2## group, wherein R is as defined above and R.sub.3 is a member selected from the group consisting of a hydrogen atom, a methyl group and a phenyl group, and a 2-, 3-, or 4-pyridyl group, or the HX salts thereof, wherein X represents a pharmaceutically acceptable acid addition salt anion, are prepared using optically active m-hydroxy-.alpha.-[(methylamino)methyl]benzyl alcohol (phenylephrine).

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or methyl,R.sub.2 and R.sub.3, together with each other and the nitrogen atom to which they are attached, form a saturated or unsaturated heterocyclic ring system which may optionally contain one or more additional heteroatoms, andA is lower alkylene or aryl-lower alkylene, and nontoxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as inducers of the formation of interferon.

Abstract: Trichlorothiazole of the formula ##STR1## IS PREPARED BY REACTING 1,2,2,2-TETRACHLOROETHYL-ISOCYANIDEDICHLORIDE OF THE FORMULA ##STR2## WITH 1 TO 1.2 TIMES THE STOICHIOMETRIC AMOUNT OF SULFUR AT A TEMPERATURE OF ABOUT 150.degree. TO 250.degree. C, preferably about 170.degree. to 230.degree. C.

Abstract: This invention discloses new compounds of the formula ##STR1## wherein R.sup.1 is selected from the group consisting of butyl, pentyl, hexyl and trifluoromethyl; R.sup.2 is selected from the group consisting of alkyl, alkenyl, haloalkyl and ##STR2## wherein R.sup.4 and R.sup.5 are each selected from the group consisting of hydrogen and alkyl; and R.sup.3 is selected from the group consisting of alkyl, alkenyl, haloalkyl, alkynyl, alkoxyalkyl, cycloalkyl and ##STR3## WHEREIN X is selected from the group consisting of alkyl, alkoxy, halogen, haloalkyl, alkylthio, nitro and cyano; n is an integer from 0 to 3; and m is the integer 0 or 1; provided that when R.sup.3 is methyl, then R.sup.2 is haloalkyl or contains at least 2 carbon atoms. Further disclosed is the herbicidal utility of the foregoing compounds.

Abstract: New benzimidazoles substituted at the 1-position with carbonyl substituents and at the 2-position with a 4-thiazolyl group are effective fungicides and anthelmintics. The compounds as well as processes for their preparation are described along with antifungal and anthelmintic compositions for their use. The 1-position substituent is a hydrocarbon group of from 5 to 12 carbon atoms connected to the carbonyl group through an oxygen or a sulfur atom. The compounds are generally prepared by contacting a 1-unsubstituted benzimidazole with a hydrocarbon radical substituted chloroformate or chlorothiol formate.

Abstract: The novel compound 2-(N-.gamma.-cyanopropyl)-amino-.DELTA..sup.1 -pyrroline is prepared by heating .gamma.-amino-butyronitrile in an inert atmosphere to a temperature up to 250.degree. C. and optionally in the presence of a solvent. The product may be hydrolyzed into pyrrolidone-2 and then polymerized to nylon-4.

Abstract: Compounds of the formula ##SPC1##Where A is selected from the group consisting of hydrogen, halogen, lower alkoxy, lower alkylthio, hydroxyl, thio, trifluoromethyl, lower diakylaminoalkyl, amino, lower alkylamino and lower dialkylamino,Where B is selected from the group consisting of hydrogen, lower alkyl, lower alkoxyl, lower alkylthio, hydroxyl, thio, trifluoromethyl, lower dialkylaminoalkoxyl, amino, lower alkylamino, and lower dialkylamino,Where C is selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxyl, lower alkylthio, hydroxyl, thio, trifluoromethyl, lower dialkylaminoalkoxy, amino, lower alkylamino and lower dialkylamino,Where D is selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, hydroxyl, thio, trifluoromethyl, lower dialkylaminoalkoxyl, amino, lower alkylamino and lower diaklamino,Where n is an integer from 2 to 12 inclusive,And Y is selected from the group consisting of amino, lower alkylamino, lower dialkylamino, and

Abstract: Disclosed is the novel compound, N-(3-methyl-5-isothiazolyl)-2-methylpentanamide, which has herbicidal properties, particularly against broad leaf and grass weeds. It is usually formulated into an agricultural composition, optionally with 5-propionylamino-3-methylissothiazole.

Abstract: N-(6-ethyl-4-thiocyanato-2-benzothiazolyl)-5-nitrofuramide is an effective agent against coccidiosis in the chicken.

Abstract: 4-Sulfanilamidothiazole having antibacterial activity is prepared from the previously unknown 4-aminothiazole.

Abstract: Thiazolinone-(2)-carboxylic acid esters having the formula: ##STR1## ARE PREPARED BY REACTING A .beta.-AMINO ACRYLIC ACID ESTER WITH CHLOROCARBOXYL SULPHENYL CHLORIDE (COCl-SCl) at a temperature of from 0.degree. to 200.degree. C. The esters are useful as plant protecting agents such as a fungicide.