Patents Examined by Robert L. Nasser
  • Patent number: 7769438
    Abstract: A method and device for determining the location of electrical activity or hyperactivity of nerve cells in an anatomical structure of a body, wherein an electrical conductivity model of the anatomical structure is generated and electrical impulses are detected by at least one electrode. Using the model and the detected electrical impulses, the location or locations of the electrical activity in the anatomical structure are determined.
    Type: Grant
    Filed: October 13, 2005
    Date of Patent: August 3, 2010
    Assignee: BrainLAB AG
    Inventors: Andreas Hartlep, Christoph Pedain
  • Patent number: 7766842
    Abstract: Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: August 3, 2010
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Quan Ni, John D. Hatlestad, Jesse W. Hartley, Jeff E. Stahmann, Jaeho Kim, Kent Lee
  • Patent number: 7769420
    Abstract: A sensor is disclosed, for implantation within a blood vessel to monitor a substance in or property of blood. In one embodiment, the sensor detects nitric oxide or a nitric oxide metabolite. In another embodiment, other substances such as glutamate, aspartate, arginine, citrulline, acetylcholine, calcium, potassium, or dopamine are monitored. The sensor may be attached to a support structure such as a stent, guidewire, or catheter. In a further embodiment, a catheter is disclosed that extracts patient fluid to a sensor outside the body for monitoring a substance or property of the patient fluid. Methods are also disclosed.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: August 3, 2010
    Inventors: James H. Silver, Darius F. Mostowfi
  • Patent number: 7762956
    Abstract: There is provided an electronic sphygmomanometer that permits a user to visually recognize easily that he or she started measurement by manipulating his or her identification key and that his or her measured value is being displayed on a display unit. The electronic sphygmomanometer 10 includes blood pressure measuring means 26 for measuring a blood pressure value, a display unit 28 for displaying the blood pressure value, a plurality of user identification keys 34 selectable by respective users, and a plurality of light emitting means 36 disposed corresponding to the respective user identification keys 34. When a user identification key A34a is manipulated, a measured blood pressure value is stored in the memory corresponding to the manipulated user identification key 34a, and the light emitting means A?36a corresponding to the manipulated user identification key A34a emits light while the blood pressure value of the user is being measured and/or being displayed.
    Type: Grant
    Filed: July 28, 2004
    Date of Patent: July 27, 2010
    Assignee: A & D Company, Ltd.
    Inventors: Shinobu Ozaki, Shigenobu Toda, Toshiharu Aiba
  • Patent number: 7764989
    Abstract: Systems and methods for detecting and/or treating nervous system disorders, such as seizures, are disclosed. Certain embodiments of the invention relate generally to implantable medical devices (IMDs) adapted to detect and treat nervous system disorders in patients with an IMD. Certain embodiments of the invention include detection of seizures based upon comparisons of long-term and short-term representations of physiological signals. Other embodiments include prediction of seizure activity based upon analysis of physiological signal levels. An embodiment of the invention monitors the quality of physiological signals, and may be able to compensate for signals of low signal quality. A further embodiment of the invention includes detection of seizure activity following the delivery of therapy.
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: July 27, 2010
    Assignee: Medtronic, Inc.
    Inventors: David L. Carlson, Eric J. Panken
  • Patent number: 7758503
    Abstract: A system and method for organization and analysis of complex and dynamically interactive time series is disclosed. One example comprises a processor based system for relational analysis of physiologic signals for providing early recognition of catastrophic and pathologic events such as pathophysiologic divergence. The processor is programmed to identify pathophysiologic divergence of at least one of first and second physiologic parameters in relationship to the other and to output an indication of the divergence. An object-based method of iterative relational processing waveform fragments in the time domain is described wherein each more complex waveform object inherits the characteristics of the waveform objects from which it is derived. The first physiologic parameter can be the amplitude and frequency of the variation in chest wall impedance or nasal pressure and the second parameter can be a measure or indication of the arterial oxygen saturation.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: July 20, 2010
    Inventors: Lawrence A. Lynn, Eric N. Lynn
  • Patent number: 7758505
    Abstract: A method and apparatus are presented for non-invasive determination of blood clotting related and blood circulation related parameters of a mammal. At least one stimulus ST is non-invasively induced in a blood containing medium in the mammal for a preset period of time tST. This at least one stimulus is selected to cause at least one of the following to occur: (a) inducing at least two of three Virchow's triad elements including abnormalities of blood flow; abnormalities of blood constituents and abnormalities of the blood vessel wall, and (b) inducing a change in red blood cell (RBC) aggregation or local blood viscosity. Measurements are non-invasively performed at a measurement location in the mammal by applying an external field thereto for a preset time period tm, a response of the measurement location to the applied field is detected, and measured data indicative thereof generated.
    Type: Grant
    Filed: November 27, 2006
    Date of Patent: July 20, 2010
    Assignee: ELFI-Tech Ltd.
    Inventors: Ilya Fine, Leonid Shvartsman
  • Patent number: 7761130
    Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: July 20, 2010
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, James H. Brauker, Paul V. Goode, Apurv U. Kamath, James R. Petisce, Kum Ming Woo, Melissa A. Nicholas, Robert J. Boock, Monica A. Rixman, John Burd, Rathbun K. Rhodes, Mark A. Tapsak
  • Patent number: 7761145
    Abstract: Systems and methods for detecting and/or treating nervous system disorders, such as seizures, are disclosed. Certain embodiments of the invention relate generally to implantable medical devices (IMDs) adapted to detect and treat nervous system disorders in patients with an IMD. Certain embodiments of the invention include detection of seizures based upon comparisons of long-term and short-term representations of physiological signals. Other embodiments include prediction of seizure activity based upon analysis of physiological signal levels. An embodiment of the invention monitors the quality of physiological signals, and may be able to compensate for signals of low signal quality. A further embodiment of the invention includes detection of seizure activity following the delivery of therapy.
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: July 20, 2010
    Assignee: Medtronic, Inc.
    Inventors: Nathalie Virag, Rolf Vetter
  • Patent number: 7753845
    Abstract: A system (10) for collecting a plurality of diagnostic information and transmitting the diagnostic information to a remote location. The system (10) comprises a glove member (12) adaptable to be worn on a person's hand and an interface unit (20) in electrical communication with the glove member (12). The interface unit (20) is capable of transmitting information to, and receiving information from, a remote location. The glove member (12) comprises a palm portion (1), a wrist portion (3) and five phalange portions (5-13). The glove member (12) further comprises an EKG diagnostic device, a blood pressure and pulse rate diagnostic device (54) and a temperature device (64). The glove member (12) may also further comprise a % O2 diagnostic device (70) and an auscultation device (80).
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: July 13, 2010
    Assignee: INEEDMD.com, Inc.
    Inventors: Govindan Gopinathan, Arthur R. Tilford
  • Patent number: 7756575
    Abstract: Provided is a health diagnosis apparatus and method in which brain waves are sequentially measured from the frontal lobe of a human body that is to be diagnosed when the eyes are in an eyes-open and eyes-closed state, the measured brain waves are fast Fourier transformed to then be accumulated, and then the health conditions of the respective portions of the human body can be determined according to the patterns with respective frequencies. The health condition diagnosis method includes measuring brain waves; performing a fast-Fourier-transform on the measured brain waves; classifying the frequency-based brain wave data into opened and closed eye state brain waves to thus accumulate the classified result; finding a specific frequency and a pattern thereof which repeats from the accumulated brain wave data; correspondingly connecting the frequency and the respective portions of the human body based on the specific frequency pattern; and determining the health condition of the human body.
    Type: Grant
    Filed: September 5, 2006
    Date of Patent: July 13, 2010
    Assignee: Braintech Corporation
    Inventor: Pyong-Woon Park
  • Patent number: 7756574
    Abstract: In a biological signal utilizing appliance, an appliance control section controls the appliance in accordance with user's manipulation. At that time, an operation content is presented to a user through an operation presentation section. A biological signal detection section measures user's biological signal and detects from the biological signal the presence or absence of an event-related potential at the time point when time obtained by adding a predetermined shift time of approximately 150 ms to 600 ms elapses after a timing, as a starting point, when the operation content is presented. Upon detection of the event-related potential, a manipulation cancellation section instructs the appliance control section to cancel the presented operation content.
    Type: Grant
    Filed: January 6, 2006
    Date of Patent: July 13, 2010
    Assignee: Panasonic Corporation
    Inventors: Shoichi Araki, Koji Morikawa, Shinobu Adachi
  • Patent number: 7756561
    Abstract: Method and apparatus for providing a disposable power supply source integrated into the housing of the transmitter unit mount that is placed on the skin of the patient, and configured to receive the transmitter unit is disclosed. The transmitter unit mount is configured to be disposable with the analyte sensor so that power supply providing power to the transmitter unit is also replaced. The transmitter unit may include a rechargeable battery that is recharged by the power supply unit of the transmitter unit mount when the transmitter is mounted to the transmitter unit mount. Other energy store configurations including single large capacitor (supercap) or a capacitor and DC/DC converter configurations are disclosed.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: July 13, 2010
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Christopher V. Reggiardo, Martin J. Fennell
  • Patent number: 7753853
    Abstract: Left atrial access apparatus and methods are described herein. Different parameters, such as oxygen saturation difference, between the left and right atrial chambers is utilized to guide a needle or catheter into a desired position within the heart. Various sensing elements can be utilized to detect the physiological parameter difference, such as oxygen levels, in the left atrium. The sensor can be carried by the needle, at its tip or along its body, and can measure the physiological parameter levels contained in the blood, fluid, or tissue.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: July 13, 2010
    Assignee: Hansen Medical, Inc.
    Inventor: Vahid Saadat
  • Patent number: 7753854
    Abstract: A technique is disclosed for determining blood flow in a living body by changing the thermal energy level in the venous blood flow path and determining temperatures in both the venous and arterial blood flow paths. Blood flow is calculated as a function of the change in energy level and the temperature differences in the venous and arterial blood flow paths.
    Type: Grant
    Filed: March 2, 2009
    Date of Patent: July 13, 2010
    Assignee: Thermal Technologies, Inc
    Inventor: Harry Frederick Bowman
  • Patent number: 7751864
    Abstract: A method of operating an electrochemical analyte sensor having one or more electrodes may comprise applying a time-varying input signal to at least one of the one or more electrodes, monitoring a time-varying output signal produced by the sensor in response to application of the time-varying input signal, determining a complex impedance of the sensor based on the time-varying input and output signals, and determining from the complex impedance information relating to operation of the sensor.
    Type: Grant
    Filed: March 1, 2007
    Date of Patent: July 6, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Harvey B. Buck, Jr.
  • Patent number: 7751877
    Abstract: A system and method for a neural interface system with a unique identification code includes a sensor including a plurality of electrodes to detect multicellular signals, an processing unit to process the signals from the sensor into a suitable control signal for a controllable device such as a computer or prosthetic limb. The unique identification code is embedded in one or more discrete components of the system. Internal and external system checks for compatibility and methods of ensuring safe and effective performance of a system with detachable components are also disclosed.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: July 6, 2010
    Assignee: BrainGate Co., LLC
    Inventors: J. Christopher Flaherty, L. Renée Capachione, Daniel S. Morris, Abraham H. Caplan, Maryam Saleh, K. Shane Guillory
  • Patent number: 7744541
    Abstract: A monitoring device may include logic to receive arterial blood pressure data associated with a patient and receive tissue hemoglobin data associated with the patient. The logic may also calculate a linear correlation between the arterial blood pressure data and the tissue hemoglobin data. The correlation may be used to assess vascular reactivity.
    Type: Grant
    Filed: July 29, 2008
    Date of Patent: June 29, 2010
    Assignees: Raba Equity Partners II, LLC, The Johns Hopkins University
    Inventors: Robert A. Baruch, Ken M. Brady
  • Patent number: 7744531
    Abstract: Method of assessing the adhesion of soils or exudates to the skin. The method may allow for an assessment of the amount of artificial bowel movement remaining on the skin following treatment with a lotion.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: June 29, 2010
    Assignee: The Procter & Gamble Company
    Inventors: Randall Glenn Marsh, Kristin Hofmann Miller, Andrea Dannenberg
  • Patent number: 7736311
    Abstract: An automatic skin perfusion measuring system including instrumentation that automatically analyzes perfusion measurements to identify motion artifact and SPP values and a sensor placement device is provided. The instrumentation is configured to ignore motion artifact. Perfusion measurements are designated as SPP values if various criteria are met. SPP value criteria pertain to factors including cuff pressure, perfusion, perfusion change percentages relative to previous and subsequent perfusion measurements, and whether perfusion measurements are increasing or decreasing relative to previous and subsequent perfusion measurements. The sensor placement device assures reliable data is produced when multiple measurements are desired.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: June 15, 2010
    Assignee: Vasamed, Inc.
    Inventors: Daniel J. Bartnik, Brandon W. Reynolds, Irvin T. Pierskalla