Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.

Abstract: An ultrasound diagnostic apparatus according to an embodiment includes image processing circuitry. The image processing circuitry acquires, based on a result of ultrasound scanning performed on a subject, blood flow information including a value that indicates a blood flow at each position within the subject and tissue property information including a value that indicates tissue properties at each position within the subject. The image processing circuitry generates a first image in which a difference in value in the blood flow information is represented by at least a difference in hue and a second image in which a difference in value in the tissue property information is represented by a difference other than the difference in hue. The image processing circuitry generates a combined image by combining the first image and the second image.

Abstract: The invention relates to a passive pressure sensor (501) for being introduced into the circulatory system of a human being and for being wirelessly read out by an outside reading system. The pressure sensor comprises a casing (502) with a diffusion blocking layer for maintaining a predetermined pressure within the casing and a magneto-mechanical oscillator with a magnetic object (508) providing a permanent magnetic moment. The magneto-mechanical oscillator transduces an external magnetic or electromagnetic excitation field into a mechanical oscillation of the magnetic object, wherein at least a part of the casing is flexible for allowing to transduce external pressure changes into changes of the mechanical oscillation of the magnetic object. The pressure sensor can be very small and nevertheless provide high quality pressure sensing.

Abstract: A method of tracking a position of a catheter within a patient includes securing a navigational reference at a reference location within the patient, defining the reference location as the origin of a coordinate system, determining a location of an electrode moving within the patient relative to that coordinate system, monitoring for a dislodgement of the navigational reference from the initial reference location, for example by measuring the navigational reference relative to a far field reference outside the patient's body, and generating a signal indicating that the navigational reference has dislodged from the reference location. Upon dislodgement, a user may be provided with guidance to help reposition and secure the navigational reference to the initial reference location, or the navigational reference may be automatically repositioned and secured to the initial reference location. Alternatively, a reference adjustment may be calculated to compensate for the changed reference point/origin.

Abstract: An ultrasonic diagnostic apparatus according to an embodiment comprises an ultrasonic probe, image generation circuitry, and processing circuitry. The ultrasonic probe performs ultrasonic scanning on a two-dimensional region of a subject. The image generation circuitry generates ultrasonic image data corresponding to the two-dimensional region. The processing circuitry calculates a characteristic amount of a structure that is detected from each of a plurality of pieces of ultrasonic image data generated by the ultrasonic scanning at different positions. The processing circuitry outputs information based on a comparison result of the calculated characteristic amounts.

Abstract: A medical system includes an elongate instrument, a tracking system, and one or more processors configured to: receive image data of a set of connected passageways of a patient anatomy; model the set as a plurality of linked bounded-surface elements, each linked bounded-surface element defined in part by basepoints on an anatomical centerline, an element centerline spanning a shortest distance between the basepoints, and a radius; receive position information for a point on the instrument when disposed in the set; based on a comparison of the received position information to the plurality of linked bounded-surface elements, generate adjusted position information for the point; match one of the plurality of linked bounded-surface elements to the point to register the instrument to the image data; create an adjusted instrument image with the adjusted position information; and generate a composite image including the image data of the set and the adjusted instrument image.

Abstract: A magnetometer includes: a substrate; a diamond layer on the substrate, in which the diamond layer includes a defect sub-layer including multiple lattice point defects; a microwave field transmitter; an optical source configured to emit light including a first wavelength that excites the multiple lattice point defects from a ground state to an excited state; a photodetector arranged to detect photoluminescence including a second wavelength emitted from the defect sub-layer, in which the first wavelength is different from the second wavelength; and a magnet arranged adjacent to the defect sub-layer.

Abstract: A Multiple Aperture Ultrasound Imaging (MAUI) probe or transducer is uniquely capable of simultaneous imaging of a region of interest from separate apertures of ultrasound arrays. Some embodiments provide systems and methods for designing, building and using ultrasound probes having continuous arrays of ultrasound transducers which may have a substantially continuous concave curved shape in two or three dimensions (i.e., concave relative to an object to be imaged). Other embodiments herein provide systems and methods for designing, building and using ultrasound imaging probes having other unique configurations, such as adjustable probes and probes with variable configurations.

Abstract: Devices and methods for vascular navigation, assessment and/or diagnosis are disclosed where a location detection system generally includes an elongate body defining a lumen at least partially along a length of the elongate body. One or more sensors are positioned near or at a distal tip of the elongate body and one or more openings are defined along the elongate body in proximity to the one or more sensors. The one or more openings are configured to control a boundary distance between the one or more sensors and a fluid with a parameter of a known initial value when emitted from the one or more openings. A controller is in communication with the one or more sensors and is configured to track a change in the parameter relating to concentration over the one or more sensors and determine a position of the one or more sensors within a body.

Abstract: Aspects described herein disclose devices, systems, and methods for use in contexts such as minimally invasive surgery (MIS). Methods of use of radio frequency (RF) techniques for improved nerve detection in association with an ultrasound detection system are described. The methods include the use of RF echoes in the detection of tissue dependent features. The methods also include use of an RF classifier to reduce false positives. System dependent features are accounted for through use of a calibration spectrum or through non-parametric model estimation using machine learning.

Abstract: A plurality of ultrasound frames of a fetus are acquired using an ultrasound scanner, which may be oriented arbitrarily with respect to the fetus during the acquisition. The ultrasound frames are processed against an artificial intelligence model to predict a different cut line on each of the ultrasound frames. Each cut line is predicted to be exterior to an image of the fetus appearing on the ultrasound frame. The different cut lines on the plurality of ultrasound frames are then used to identify ultrasound data in the image frames to generate a 3D representation of the fetus.

Abstract: A medical robot system, including a robot coupled to an effectuator element with the robot configured for controlled movement and positioning. The system may include a transmitter configured to emit signals, and the transmitter is coupled to an instrument coupled to the effectuator element. The system may further include a motor assembly coupled to the robot and a plurality of receivers configured to receive the signals emitted by the transmitter. A control unit is coupled to the motor assembly and the plurality of receivers, and the control unit is configured to supply instruction signals to the motor assembly. The instruction signals can be configured to cause the motor assembly to selectively move the effectuator element and is further configured to (i) calculate a position of the transmitter; (ii) display the position of the at least one transmitter; and (iii) selectively control actuation of the motor assembly.

Abstract: An objective of the present invention is to provide a biomagnetism measurement device capable of three-dimensionally acquiring magnetism information of a living body with ease. This biomagnetism measurement device (101) is for measuring biomagnetism using a plurality of magnetic sensors (1) at the same time. The plurality of magnetic sensors (1) is retained by a retaining part (10) (a first retaining portion [11] and a second retaining portion [12]) so as to have different measurement directions. Furthermore, the retaining part (10) (the first retaining portion [11] and the second retaining portion [12]) has arranged thereon the plurality of magnetic sensors (1) so as to enable biomagnetism to be measured at a plurality of sites at the same time. The magnetic sensor (1) comprises a means for detecting the biomagnetism in a temperature environment commensurate with normal temperature.

Abstract: An imaging compatible device for applying a plurality of different loads to a foot for evaluating the Lisfranc joint of a patient is configured to move the ball of the foot in an axial direction, a lateral direction, and a torsional direction to assess a state of the Lisfranc joint.

Abstract: A method for multi-modal tissue classification of an anatomical tissue involves a generation of a tissue classification volume (40) of the anatomical tissue derived from a spatial registration and an image extraction of one or more MRI features of the anatomical tissue and one or more ultrasound image features of the anatomical tissue. The method further involves a classification of each voxel of the tissue classification volume (40) as one of a plurality of tissue types including a healthy tissue voxel and an unhealthy tissue voxel.

Abstract: A system provides combined diffuse optical microscopy (DOM) and fluorescence endomicroscopy (FE). The system may use a single light source which generates structured illumination for both modalities. FE and DOM images may be displayed for qualitative assessment. Quantitative assessments may be based on both FE and DOM images. The quantitative assessments may be applied to characterize tissues. Some embodiments provide multi-spectral DOM.

Abstract: In accordance with the invention, a reliable apparatus for guiding an ablation probe to a target location inside a human body is thus provided. The apparatus allows incorporation of a conventional metal operating room table, but further comprises a substantially non-conductive separation structure positioned over the metal operating room table and underneath a horizontally oriented electromagnetic field generator. The resultant structure is adapted to support a human body in the prone or supine position over the operating table. Further support padding may also be provided. The electromagnetic field generator creates an electromagnetic field that extends through the torso of said human body positioned over the electromagnetic field generator. An ultrasound probe and ablation probe interacts with the electromagnetic field to generate positional information that is processed by a computing device to generate a graphic representation of location information on a display device.

Abstract: Systems and methods can include wearable, non-invasive ultrasound modalities for treating a variety of medical conditions, including but not limited to peripheral vascular disease. The modality could be therapeutic ultrasound (TUS), and be configured to promote angiogenesis within a patient via stimulation of cavitation and shear stress, among other mechanisms.

Abstract: The present disclosure relates to a tracking system for augmented reality in a clinical setting. Specifically, the present disclosure relates to an approach for combining hardware-based tracking and computer vision-based tracking in order to accurately overlay a projected image onto a video image.

Abstract: A method of tracking a medical instrument comprises receiving a model of an anatomical passageway formation and receiving a set of ordered sensor records for the medical instrument. The set of ordered sensor records provide a path history of the medical instrument. The method further comprises registering the medical instrument with the model of the anatomical passageway formation based on the path history. The method further includes displaying a virtual visualization image in a display system, the virtual visualization image being based on the registering of the medical instrument with the model of the anatomical passageway and depicting a rendered view of the model of the anatomical passageway from a perspective of the medical instrument within the model of the anatomical passageway.