Abstract: Devices, systems, and methods for generating therapy annotations for display on a graphical user interface are disclosed herein. In some embodiments, therapy annotations can correspond to a location of a tip section of a catheter relative to an anatomical structure of a patient when therapy is delivered to the anatomical structure. One or more properties of the therapy annotations can be based at least in part on signals received from sensors distributed about the tip section of the catheter and/or on other characteristics of therapy delivery. The therapy annotations can be displayed alone or in combination with a three-dimensional surface representation of the anatomical structure, a representation of the catheter, and/or other visual indicia, such as a therapy contour, a distance from a nearest therapy site and/or the most recent therapy site, and/or a representation of gaps between two therapy sites.

Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.

Abstract: A cooled radio-frequency (RF) ablation probe is provided. The RF ablation probe includes a first tubular portion defining at least part of an internal cavity for circulating coolant through the cooled RF ablation probe; a second tubular portion surrounding the first tubular portion along a first portion of the length of the cooled RF ablation probe; a third tubular portion surrounding the second tubular portion along a second portion of the length of the cooled RF ablation probe; and a fourth tubular portion surrounding the third tubular portion along a third portion of the length of the cooled RF ablation probe. A gap is defined between the third tubular portion and the fourth tubular portion that can be filled with air or a vacuum can be formed in the gap to insulate one or more thermocouples attached to the fourth tubular portion from the coolant in the internal cavity.

Abstract: An electrophysiological catheter and an ablation system comprising a control device, an ablation energy output device and the electrophysiological catheter. The control device controls the ablation energy output device to selectively provide a first fluid or a second fluid that is a frozen liquid to the electrophysiological catheter. When the ablation energy output device provides the first fluid, the control device controls a first heating component on the electrophysiological catheter to work to heat the fluid entering the electrophysiological catheter for spraying a thermal ablation gas onto the inner surface of a balloon; and when the ablation energy output device provides frozen liquid, the control device controls the first heating component not to work to directly spray the frozen liquid to the inner surface of the balloon.

Abstract: Systems and related methods for identifying and/or ablating targeted nerves are provided. A probe with stimulating electrodes and/or ablation members are provided. The probe may be inserted into a nasal cavity and current may be introduced through the electrodes to stimulate a targeted area. The response to stimulation may be used to identify the targeted nerve. Once identified, the ablation member may ablate the targeted nerve.

Abstract: A device, system, and method for performing a variety of treatment procedures safely with a single treatment device. For example, a system is provided that includes a treatment device with a highly conformable balloon that is inflated at a constant pressure and that remains “soft” during use, which enhances balloon-tissue contact, treatment efficacy, and patient safety. In one embodiment, a system for ablating tissue comprises: a treatment device including a highly conformable balloon; a control unit including a fluid supply reservoir in fluid communication with the highly conformable balloon, the control unit being configured to deliver fluid from the fluid supply reservoir to the highly conformable balloon such that the highly conformable balloon is maintained at a balloon pressure of between 0.2 psig and 3.0 psig.

Abstract: Conventional varicose vein techniques suffer from a number of disadvantages and potential complications, including, for example, a risk for the development of hematomas, swelling, and blood clots, post-surgical pain and nerve injury, a potential for spontaneous regeneration and undesired resumption of varicosity, a need for a highly skilled surgical professional, as well as, in certain instances, a prolonged recovery period, accompanied by severe limitations on post-surgical activity. The present invention overcomes the disadvantages and deficiencies of the prior art by providing a method for percutaneously occluding and dividing a varicose vein or other problematic vessel, a rapid, reliable, less invasive therapy that may be readily, reliably, and successfully performed by minimally skilled personnel around the world in a variety of medical settings.

Abstract: Apparatus, including a guidewire, having a distal end dimensioned to penetrate into a nasal sinus and a balloon, which is fitted over the guidewire in proximity to the distal end. There is an inflation channel, which runs along the guidewire and is coupled to convey a pressurized fluid into the balloon so as to inflate the balloon. The apparatus also includes a first electrode, fixedly attached to a distal tip of the guidewire, and a second electrode, fixedly attached to the guidewire at a location proximal to the distal tip. There are conductive leads running along the guidewire and coupled to apply an electrical potential between the first and second electrodes.

Abstract: In an illustrative embodiment, systems and methods for treatment of nerves present in a wall of a human renal pelvis are described. One system uses a sheath to access a position in or near the renal pelvis via the urinary tract. An effector inserted through the sheath has an uncooled distal region formed with a superelastic wire that supports at least four non-insulated, preferably spherical electrodes distributed along the distal region. The distal region expands within the renal pelvis, and vacuum applied through the sheath at least partially evacuates the renal pelvis to draw opposing walls of the renal pelvis inwards and compress the distal region somewhat from its expanded form, placing the electrodes in intimate contact with different points along the renal pelvic wall. Energy is applied to the electrodes to create discrete lesions at the points of contact of the electrodes.

Abstract: An illuminated energy device includes a handle, an optical waveguide coupled to the handle, and an energy tip such as an electrode coupled to the optical waveguide. The optical waveguide is preferably adjustably coupled to the optical waveguide, and adjustment of the optical waveguide moves a distal end of the optical waveguide closer to or further away from a target such as tissue in a surgical field.

Abstract: A microwave ablation antenna assembly including a coaxial cable terminating in a radiating section, a first tubular member circumscribing the coaxial cable and spaced therefrom to permit fluid flow therebetween, and a second tubular member circumscribing the first tubular member and spaced therefrom to permit fluid flow therebetween. The microwave ablation antenna assembly further includes a hub configured to receive the coaxial cable, first tubular member, and second tubular member, the hub including a fluid inflow chamber and a fluid outflow chamber and an integrated hub divider and hub cap separating the fluid inflow chamber from the fluid outflow chamber and prohibiting fluid flow between the inflow chamber and outflow chamber except via the spacing between the coaxial cable and the first tubular member and between the first tubular member and the second tubular member.

Abstract: A medical system includes a catheter, a light source, a detector, a circulator, and a processor. The catheter includes a distal-end assembly for performing a medical operation on tissue in a cavity of an organ of a patient, the distal-end assembly including an optical fiber configured to guide transmitted light to interact with the tissue of the cavity, and to guide returned light that interacted with the tissue. The light source is configured to produce the transmitted light. The detector is configured to measure the returned light. The circulator is configured to couple the transmitted light from the light source to the optical fiber, and to couple the returned light from the optical fiber to the detector. The processor is configured to identify a contact of the distal-end assembly with the tissue based on the returned light measured by the detector, and to indicate the identified contact to a user.

Abstract: Presented are an apparatus and method for fluid evacuation. An exemplary fluid evacuation system includes a surgical apparatus having a fluid conduit therethrough. The fluid conduit includes a gaseous fluid sorbent material. Additionally, the fluid conduit is fluidly coupled with a vacuum tube fluidly coupled with a vacuum source, wherein the vacuum source is operable to create a flow of fluid through the surgical apparatus fluid conduit and the vacuum tube.

Abstract: A resecting probe includes a shaft assembly having an outer sleeve and an inner sleeve. The outer sleeve has an axial bore and an outer window in a distal side thereof, and the inner sleeve has an axial extraction channel and inner window in a distal side thereof. The inner sleeve is rotationally disposed in the axial bore of the outer sleeve to allow the inner sleeve window to be rotated in and out of alignment with the outer sleeve window, and the shaft assembly forms a flow aperture in a distal portion when the inner cutting window and the outer cutting window are out of alignment. An electrode is carried on the inner sleeve, and a motor drive is coupled to rotate the inner sleeve relative to the outer sleeve.

Abstract: A method of operating a catheter assembly including monitoring a gap feedback signal indicative of a distance between a first tissue contact surface and a second tissue contact surface. Producing, via a user interface of the catheter assembly, a graphical depiction of the first tissue contact surface and the second tissue contact surface spaced apart from the first tissue contact surface by the distance. Producing, via the user interface of the catheter assembly, a gap distance warning when the gap feedback signal indicates that the distance is outside of a target gap range.

Abstract: An electrosurgical probe can be detachably secured to a handpiece having a motor drive unit and an RF current contact. The electrosurgical probe includes an elongate shaft having a longitudinal axis, a distal dielectric tip, and a proximal hub which is detachably securable to the handpiece. A hook electrode is reciprocatably mounted in the distal dielectric tip, and an RF connector on the hub is couplable to the RF current contact in the handpiece when the hub is secured to the handpiece. A drive mechanism in the hub mechanically couples to the hook electrode, and drive mechanism engages a rotational component in the motor drive unit when the hub is secured to the handpiece. The drive mechanism converts rotational motion from the rotational component into axial reciprocation and transmits the axial reciprocation to the hook electrode to axially displace the hook electrode between a non-extended position and an extended position relative to the dielectric tip.

Abstract: A multiple-modality ablation probe can include a tube configured to transmit mechanical modality energy from a first end to an obstruction in contact with a second end. A first optical transmission media can extend along the tube to transmit laser modality energy from a laser energy source to the obstruction. A connector assembly can be mechanically coupled with the first end of the tube and with the first end of the first optical transmission media. The connector assembly can be configured for user-attachment and detachment of the tube and the first optical transmission media with a mechanical energy source coupling and a laser energy source coupling, respectively.

Abstract: An ablation apparatus for creating a lesion in target tissue has a handle, an elongate shaft extending from the handle and a distal ablation portion. The distal ablation portion includes a cryogen flow manifold defining a plurality of fluid pathways between an insert body and a sleeve. Cryogen is circulated through the plurality of fluid pathways to create the lesion in the target tissue.

Abstract: Aspects of the present disclosure are directed toward systems and methods for detecting force applied to a distal tip of a medical catheter. In some embodiments, a medical catheter with a deformable body near a distal tip of the catheter deforms in response to a force applied at the distal tip, and a force sensor detects various components of the deformation. Processor circuitry may then, based on the detected components of the deformation, determine a force applied to the distal tip of the catheter.

Abstract: Devices and methods are disclosed for treating tissue with microwave energy. Such devices and methods are able to treat cavities or surface tissue by creating one or more area or volumetric lesions. Also disclosed are flexible, low-profile devices that can be inserted non-invasively or minimally invasively near or into the target tissue as well as microwave antennas designed to generate ablation profiles that can ablate a large area or a large volume of target tissue in a single ablation. The devices include antennas wherein the field profile generated by an antenna is tailored and optimized for a particular clinical application. The antennas use unique properties of microwaves such as interaction of a microwave field with a metallic object and the use of additional shaping elements to shape the microwave field.