Patents Examined by S. Jiang
  • Patent number: 6455574
    Abstract: This invention relates to pharmaceutical combinations of amlodipine or a pharmaceutically acceptable acid addition salt thereof and atorvastatin or a pharmaceutically acceptable salt thereof, kits containing such combinations and methods of using such combinations to treat subjects suffering from angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and to treat subjects presenting with symptoms of cardiac risk, including humans. This invention also relates to additive and synergistic combinations of amlodipine and atorvastatin whereby those synergistic combinations are useful in treating subjects suffering from angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and those subjects presenting with symptoms of cardiac risk, including humans.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: September 24, 2002
    Assignee: Pfizer Inc.
    Inventor: Jan Buch
  • Patent number: 6444661
    Abstract: Duplex polynucleotides containing damage or errors are detected with hindered intercalating compounds which are capable of intercalating only in the presence of such damage or error. Conditions characterized by the presence of polynucleotide errors or damage are treated with such compounds that are capable of catalyzing polynucleotide cleavage with light.
    Type: Grant
    Filed: November 23, 1999
    Date of Patent: September 3, 2002
    Assignee: California Institute of Technology
    Inventors: Jacqueline K. Barton, Brian A. Jackson, Brian P. Hudson
  • Patent number: 6440985
    Abstract: Methods are provided for the treatment and prophylaxis of viral infection and disease associated with such infection.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: August 27, 2002
    Assignee: ViroPharma Incorporated
    Inventors: Thomas R. Bailey, Dorothy C. Young
  • Patent number: 6433022
    Abstract: There is provided a method of contraception, comprising exposing a spermicidally sufficient quantity of an agent to spermatozoa. The agent is a quinone represented by the following formula: Each group A is H or an electron releasing moiety. The agent is capable of generating reactive oxygen species including free radicals, superoxide and hydrogen peroxide in the presence of spermatozoa.
    Type: Grant
    Filed: September 13, 1999
    Date of Patent: August 13, 2002
    Assignee: Medical Research Council
    Inventor: Robert John Aitken
  • Patent number: 6429217
    Abstract: Controlled cessation of heart beat during coronary bypass surgery and other cardiac surgeries on a beating heart improves surgical technique, and is achieved typically by electrical stimulation of the vagus nerve and administration of a combination of drugs.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: August 6, 2002
    Assignee: Emory University
    Inventor: John D. Puskas
  • Patent number: 6387959
    Abstract: The invention relates to the field of antiviral agents, and more specifically to antiviral therapy. The invention provides use of at least one compound or mixture of compounds of the general formula or a functional equivalent or pharmaceutically acceptable salt, ester or hydrate thereof for the treatment of a viral infection.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: May 14, 2002
    Assignees: Universiteit Utrecht, Universitair Medisch Centrum Utrecht
    Inventor: Johannes Servatius Leonardus Maria Nottet
  • Patent number: 6344448
    Abstract: A method and compound having betamethasone dipropionate and all-trans-retinoic is disclosed for the treatment of hair loss. The method also includes identifying any underlying conditions causing hair loss and administration of a salve of betamethasone dipropionate and all-trans-retinoic acid to the affected areas.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: February 5, 2002
    Assignee: STB Family Limited Partnership
    Inventor: Sandra Brown