Patents Examined by Sean M Luck
  • Patent number: 10703647
    Abstract: A water purifier that includes: a water storage tank that includes an interior area and a first opening to the interior area; a cover unit that is configured to cover the first opening and that includes: a frame body that includes a second opening, and a water storage tank cover that is coupled to the frame body and that is configured to rotate about an axis such that the water storage tank cover opens or closes the second opening; a sterilizer that is configured to sterilize water in the water storage tank; a switching module that is configured to control electric power supply to the sterilizer; and an operation member that is configured to control the switching module based on the water storage tank cover being opened or closed is disclosed.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: July 7, 2020
    Assignee: LG Electronics Inc.
    Inventors: Myounggon Kim, Youngjin Kim, Kowoon Baek, Changgeun Lee, Jongho Park
  • Patent number: 10699888
    Abstract: A data independent acquisition method of mass spectrometry for analyzing a sample within a mass range of interest as it elutes from a chromatography system. The method comprises selecting precursor ions within a mass range of interest to be analyzed, performing at least one MS1 scan of the precursor ions using a Fourier Transform mass analyser and performing a set of MS2 scans by segmenting the precursor ions into a plurality of precursor mass segments, each precursor mass segment having a mass range of no greater than 5 amu, and for each precursor mass segment fragmenting the precursor ions within that precursor mass segment and performing an MS2 scan of the fragmented ions.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: June 30, 2020
    Assignee: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Anastassios Giannakopulos, Alexander Makarov, Christian Albrecht Hock, Nicolaie Eugen Damoc, Hamish Stewart
  • Patent number: 10684308
    Abstract: Techniques are disclosed for stabilizing soft specimen traditionally considered too fragile for APT instruments. These specimens include biological samples, polymers and other fragile materials. For this purpose, a protective structure is disclosed that surrounds the sides of the specimen by supporting walls while only exposing the very end or terminus of the specimen to the electrostatic field of the APT instrument. The protective structure may take the form of a nanoscale conical grinder which continually machines the specimen to regenerate the terminus of the specimen in-situ. Alternately, the protective structure may take the form of a nanopipette in which the specimen is first frozen before undergoing field evaporation together with the tip of the nanopipette. Heretofore only routinely possible for rigid and hard materials, the design thus extends APT analysis to produce three-dimensional atomic-scale maps of soft specimens.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: June 16, 2020
    Inventor: Gregory Hirsch
  • Patent number: 10685827
    Abstract: A quadrupole ion trap apparatus includes a main electrode, a first end-cap electrode, a second end-cap electrode, and a phase-controlled waveform synthesizer. The phase-controlled waveform synthesizer generates a main RE waveform for the main electrode. The main RE waveform includes a plurality of sinuous waveform segments each of which is a part of a sine wave, and a plurality of phase conjunction segments each of which is non-sinuous. Each of the sinuous waveform segments is bridged to another sinuous waveform segment via one of the phase conjunction segments, so as to perform ordering of micro motions of sample ions trapped by the electrodes.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: June 16, 2020
    Inventors: Chun-Yen Cheng, Yao-Hsin Tseng, Szu-Wei Chou, Yi-Kun Lee, Shih-Chieh Yang, Hung-Liang Hsieh
  • Patent number: 10679819
    Abstract: The invention relates to an aberration correcting device for correcting aberrations of focusing lenses in an electron microscope. The device comprises a first and a second electron mirror, each comprising an electron beam reflecting face. Between said mirrors an intermediate space is arranged. The intermediate space comprises an input side and an exit side. The first and second electron mirrors are arranged at opposite sides of the intermediate space, wherein the reflective face of the first and second mirror are arranged facing said intermediate space. The first mirror is arranged at the exit side and the second mirror is arranged at the input side of the intermediate space. In use, the first mirror receives the electron beam coming from the input side and reflects said beam via the intermediate space towards the second mirror. The second mirror receives the electron beam coming from the first mirror, and reflects the electron beam via the intermediate space towards the exit side.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: June 9, 2020
    Assignee: Hitachi High-Tech Corporation
    Inventor: Pieter Kruit
  • Patent number: 10670625
    Abstract: Disclosed here is a scanning probe microscope system and method for operating the same for producing scanning probe microscope images at fast scan rates and reducing oscillation artifacts. In some embodiments, an inverse consistent image registration method is used to align forward and backward scan traces for each line of the scanning microscope image. In some embodiments, the aligned forward and backward scan traces are combined using a weighting factor favoring the scan trace with higher smoothness. In some embodiments, the scanning probe microscope image is a potentiometry map and a method is provided to extract from the potentiometry map a conductivity map.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: June 2, 2020
    Inventors: Xiaoguang Zhang, Xianqi Li, An-Ping Li, Hao Zhang, Yunmei Chen
  • Patent number: 10661246
    Abstract: A light irradiation device includes a protective tube, which has a wire insertion path therein, a light source unit facing and disposed along an upper part of the protective tube, and a gutter-shaped concave reflection mirror facing the light source unit and provided below the protective tube. The concave reflection mirror is received in a gutter-shaped concave accommodating part provided in a holding body, and has flange portions extending from the outer surface in the horizontal direction. The convex reflection mirror is detachably affixed to the holding body with the flange portions.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: May 26, 2020
    Inventor: Yasushi Omae
  • Patent number: 10656127
    Abstract: A data independent acquisition method of mass spectrometry for analysing a sample as it elutes from a chromatography system is disclosed. The method comprises the steps of: ionising the sample to produce precursor ions, selecting a precursor mass range for the sample to be analysed, performing a plurality of MS1 scans and performing at most two sets of MS2 scans. Each of the MS1 scans uses a mass analyser operated at a first, relatively higher resolution, for identification and/or quantitation of the sample in the MS1 domain across the precursor mass range. The set of MS2 scans comprises performing MS2 scans of fragmented mass range segments performed with the mass analyser, operated at a second, relatively lower resolution. In the method, the MS1 scans are interleaved throughout the performing of the set of MS2 scans such that the MS1 scans provide a mass chromatogram of the sample.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: May 19, 2020
    Assignee: Thermo Fisher Scientific (Bremen) GmbH
    Inventor: Yue Xuan
  • Patent number: 10651005
    Abstract: A source assembly for ion beam production is disclosed herein. An example source assembly may include a pair of plates separated by a distance, with each plate having an aperture, and the respective apertures aligned, and an ionization space defined at least by the distance and the respective apertures, where a ratio of the distance to an ionic mean free path of a gas in the ionization space is greater than one.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: May 12, 2020
    Assignee: FEI Company
    Inventors: Leon van Kouwen, Gerard Nicolaas Anne van Veen
  • Patent number: 10629317
    Abstract: The present invention relates to a two-dimensional magnetic-optical trap system using frequency and phase modulation with an arbitrary waveform, including: a glass cell; a coil set; and a light source module, wherein the laser source module includes: a cooling laser; a re-pumping laser; a first acousto-optic modulator; a second acousto-optic modulator; and an electro-optical modulator.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: April 21, 2020
    Inventors: Jae Hoon Lee, Jong Chul Mun
  • Patent number: 10617045
    Abstract: A glove assembly is provided for coupling an electrically-conductive glove to an enclosure wall of a radio frequency shielded enclosure. Exemplary embodiments of the glove assembly and associated shielded enclosure comprise a glove interface element, a glove and a glove securement element. The glove interface element has a cylindrical flange member, a wall securement portion extending laterally of the flange member, and a glove port extending through the flange member. The glove interface element is configured to be affixed to the enclosure wall. The glove securement element is configured to clampingly secure an open end of the glove to the flange member in mutual RF-signal-sealed engagement. Resultingly, the glove is also held in electrically-conductive communication with the shielding layer of the shielded enclosure by way of the glove interface element. The glove securement element is preferably actuatable to enable a user to selectively cause and release the clamped securement.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: April 7, 2020
    Assignee: Merakai, LLC
    Inventor: Ryan Judy
  • Patent number: 10607826
    Abstract: Atmospheric pressure ion guides are provided. The atmospheric pressure ion guides can include a multi-ring electrode structure connecting a larger opening to a smaller opening and having a series of ring electrodes with decreasing diameter and voltage going from the larger opening to the smaller opening. The electrodes can be made from stainless steel or other suitable conductive material. The multi-ring electrode structure can be contained in a housing, such as a housing made from polyetheretherketone or other suitable thermosetting polymer. The atmospheric pressure ion guide can focus ions from an ion source for use with ion detection devices such as an ion mobility spectrometer or a mass spectrometer. Methods of using the atmospheric pressure ion guides are provided, for example to focus a plurality of ions to be injected into an ion detection device. The atmospheric pressure ion guides can increase the signal intensity of the ion detection device.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: March 31, 2020
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Jared J. Boock, Joaquin Jesus Casanova, Richard A. Yost, Brian Smith
  • Patent number: 10603395
    Abstract: A fluid sterilization device includes: a straight tube that defines a processing flow passage; a light source that radiates ultraviolet light toward the processing flow passage in an axial direction of the straight tube; and a light receiving part that receives a portion of the ultraviolet light output from the light source. The straight tube is made of a fluororesin. The straight tube includes a recess formed in a part of an outer wall surface of the straight tube such that a thin part is partly provided in the straight tube. The thin part has a radial thickness from an inner wall surface of the straight tube that is smaller than a thickness in other parts. The light receiving part is provided in the recess to receive the ultraviolet light transmitted through the thin part.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: March 31, 2020
    Assignee: NIKKISO CO., LTD.
    Inventors: Tetsumi Ochi, Shinya Watanabe
  • Patent number: 10591448
    Abstract: The present disclosure relates to structural elucidation of isotopically labeled analytes using chromatography-MS and data-independent acquisition. The present disclosure can be used for rapid screening of analytes, such as the metabolome, including the simultaneous collection of both qualitative and quantitative information of known and unknown analytes.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: March 17, 2020
    Assignee: Waters Technologies Corporation
    Inventor: Giuseppe Astarita
  • Patent number: 10593511
    Abstract: A method of determining a local electric field and/or a local magnetic field in a sample and/or the dielectric constant of a material and/or the angle between the input and output surfaces of the sample, comprising illumination of the sample by an electron beam in precession mode using an illumination device, generation of a diffraction pattern, determination of the offset of the disk corresponding to the transmitted beam due to the electric field and/or the magnetic field, by comparison of the diffraction pattern and a reference diffraction pattern, determination of a deflection angle of the transmitted beam, and determination of the value of the local electric field and/or the local magnetic field of the sample and/or determination of the dielectric constant of materials and/or determination of the angle between the input and output surfaces of the sample.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: March 17, 2020
    Inventors: Benedikt Haas, David Cooper, Jean-Luc Rouviere
  • Patent number: 10593531
    Abstract: An acceleration voltage generator generates a high-voltage pulse applied to a push-out electrode, by operating a switch section to turn on and off a high direct-current voltage generated by a high-voltage power supply. A drive pulse signal is supplied from a controller to the switch section through a primary-side drive section, transformer, and secondary-side drive section. A primary-voltage controller receives a measurement result of ambient temperature of the acceleration voltage generator from a temperature sensor, and controls a primary-side power supply to change a primary-side voltage according to the temperature, thereby adjusting the voltage applied between the two ends of a primary winding of the transformer. The adjustment made on the primary-side voltage changes a slope angle of rise of a gate voltage in the MOSFET, and enables a correction to a discrepancy in the timing of the rise/fall of the high-voltage pulse caused by change in ambient temperature.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: March 17, 2020
    Inventor: Shiro Mizutani
  • Patent number: 10593514
    Abstract: An electron beam irradiation apparatus which exposes a wafer coated with an electron beam resist with an electron beam is equipped with: a stage that can be moved holding the wafer; an electron beam optical system that irradiates the wafer with an electron beam; and, an opening member, placed facing the wafer via a predetermined gap on the wafer side in the optical arrangement direction of the electron beam optical system, and having an opening through which the electron beam from the electron beam optical system passes.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: March 17, 2020
    Inventor: Yuichi Shibazaki
  • Patent number: 10586682
    Abstract: In one embodiment, a method of obtaining a beam deflection shape includes using a plurality of beams to write a line pattern on a substrate by deflecting the plurality of beams, the plurality of beams being beams in the i-th row (i is an integer satisfying 1?i?m) among multiple charged-particle beams including beams of m rows and n columns (m and n are integers equal to or greater than two), the deflection being performed in such a manner that a writing area for a beam in the j-th column (j is an integer satisfying 1?j?n?1) is continuously adjacent to a writing area for a beam in the (j+1)th column, measuring a degree of unevenness of an edge of the line pattern, and obtaining a deflection shape of the beam based on the degree of unevenness.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: March 10, 2020
    Assignee: NuFlare Technology, Inc.
    Inventors: Shunsuke Isaji, Rieko Nishimura
  • Patent number: 10583312
    Abstract: A treatment bed arranged in a tip direction of an irradiation nozzle and constructed movably, a treatment information system that manages prescription data, a treatment control system that receives a target position stored in the treatment information system to cause a main display system to display the target position, a pendant to input a movement command for the treatment bed, the main display system that receives the target position of the treatment bed from the treatment control system and displays an actual position of the treatment bed, and a patient positioning support system that calculates correction values for the target position thereof to provide the correction values to the treatment control system and the pendant are included, wherein the treatment control system sends the target position thereof to the treatment information system at a period shorter than an operation sequence thereof and stores initial values to be sent in advance.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: March 10, 2020
    Assignee: Hitachi, Ltd.
    Inventors: Daisuke Ono, Takayoshi Matsushita, Isao Furuse, Takao Kidani
  • Patent number: 10585041
    Abstract: A sample analysis system includes a Fluorescence Spectrophotometer, a liquid chromatography device, a mass spectrometer, a control device, and a sample introducer. The Fluorescence Spectrophotometer obtains a three-dimensional fluorescence spectrum including an excitation wavelength, a fluorescence wavelength, and a fluorescence intensity. The liquid chromatography device obtains a three-dimensional absorption spectrum including an elution time, an absorption wavelength, and an absorbance. The mass spectrometer obtains a three-dimensional mass spectrum including an elution time, mass information, and an ion intensity. The axes of respective spectra are set on the same scale, and the mass-charge ratio in the three-dimensional mass spectrum data obtained by the mass spectrometer is determined.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: March 10, 2020
    Assignee: Hitachi High-Tech Science Corporation
    Inventors: Jun Horigome, Masaki Watanabe, Katsutoshi Shimizu, Hideyuki Sakamoto