Patents Examined by Sharon Kennedy
  • Patent number: 7101351
    Abstract: A medical device including a syringe assembly and a shield system for delivering medicament to a patient. The syringe assembly includes a barrel defining a medicament reservoir, a needle cannula coupled to the barrel and in fluid communication with the reservoir, a plunger having a stopper positioned in the reservoir and a thumb pad for moving the plunger in the reservoir. The shield system has a first shield coupled to a forward end of the barrel, and a second shield movable from a first position disposed from the needle cannula tip to a second position covering the needle cannula tip. An urging member controlled by a retaining device urges the second shield to the second position upon movement of the stopper to a position which releases the retaining device.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: September 5, 2006
    Assignee: Becton, Dickinson and Company
    Inventors: Jamie Crawford, Frank Francavilla, Roger Groskopf
  • Patent number: 7097635
    Abstract: An apparatus for passing a guidewire through a subcutaneous tissue tunnel to enable over-the wire insertion of a catheter through the tissue tunnel. The apparatus comprises an elongated member having a distal end portion having a tip configured to advance through the tissue tunnel and an opening extending longitudinally with respect to the apparatus and dimensioned to receive the guidewire. The guidewire is inserted through the opening to pass the guidewire through the tunnel to enable subsequent insertion of the catheter.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: August 29, 2006
    Assignee: Rex Medical, L.P.
    Inventors: James F. McGuckin, Jr., Michael W. Paris, Paul Tashjian, Peter W. J. Hinchliffe
  • Patent number: 7090861
    Abstract: The present invention relates to devices that allow for linear, sustained-release of solutes with adjustable initial-release kinetics. In particular, the present invention relates to devices for delivering substances to the body of an animal. The present invention also relates to methods for delivering solutes in a constant, sustained-release fashion using the devices of the invention.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: August 15, 2006
    Assignee: Farrington Pharmaceuticals, LLC
    Inventors: Michael L. Brines, Anthony Cerami, Jean-Paul Wuerth
  • Patent number: 7090660
    Abstract: A patient medical tubing and catheter anchor and support for permanently, securely anchoring and supporting medical tubing to a patient's body including a longitudinally extending conformable base having a non-adhesive upper surface and a lower surface including a medical grade adhesive thereon. An attachment member is connected to the upper surface of the base to provide a supporting surface for receiving and supporting the tubing. The attachment member includes a center portion and at least one longitudinally extending locking strip extending from one end of the center portion and at least one other longitudinally extending locking strip extending from the other end of the center portion. The locking strips are foldable over the center portion to encapsulate a portion of the tubing between the upper surface of the locking strips and the upper surface of the center portion.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: August 15, 2006
    Assignee: Tri-State Hospital Supply Corporation
    Inventors: Jerry H. Roberts, Zane D. Myers
  • Patent number: 7092753
    Abstract: Apparatus (800) for targeted release of a molecule carried in a circulating reservoir, comprising: at least one electrode (804); and a controller (810) adapted to electrify said electrode (804) with at least one electric field, said electric field operative to have at least one desired effect related to said circulating reservoir with said molecule, wherein said electrode and said electrification are adapted such that at least one of said effects is selectively applied to a particular blood vessel that carries blood through tissue and wherein said at least one effect that is selectively applied comprises a release effect, which releases said molecule from said circulating reservoir that circulates in said blood vessel.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: August 15, 2006
    Assignee: Impulse Dynamics NV
    Inventors: Nissim Darvish, Itzhak (Itsik) Shemer
  • Patent number: 7083591
    Abstract: A surge-flow regulator (36) for use with an ophthalmic surgical instrument (12) having an infusion line (20) adapted to irrigate a surgical site with fluid and an aspiration line (24) adapted to carry the fluid and particles of lenticular debris away from the surgical site. The surge-flow regulator (36) includes a flow limiting device (40) that is placed in fluid communication with the aspiration line (24) to control surge-flow of the aspirated fluid and lenticular debris through the aspiration line (24). The lenticular debris carried in the aspiration line (24) is processed into smaller particles before the fluid and debris are introduced to the flow limiting device (40).
    Type: Grant
    Filed: September 7, 2001
    Date of Patent: August 1, 2006
    Inventor: Robert J. Cionni
  • Patent number: 7083592
    Abstract: An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid. The dermal-access member extends at least 1 mm from the protrusion. A mechanism drives the device against the skin at a calculated speed of about 6 m/s to about 18 m/s.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: August 1, 2006
    Assignee: Becton Dickinson and Company
    Inventors: Alexander G. Lastovich, James K. Fentress, Julia Griggs, Ronald J. Pettis, Diane Sutter, Frank E. Martin, M. Ishaq Haider
  • Patent number: 7081107
    Abstract: A syringe (and a prefilled syringe) of a structure with ventilation means allowing a pusher to be easily pushed or pulled in use, providing an excellent operability of discharging (injecting) chemicals, making it hard for foreign matter such as dirt and dust to enter into a syringe outer tube when not in use during storage or transporation, capable of assuring, by itself, the sanitation of the syringe outer tube when not in use, and allowed to be shipped without individually packaging the syringe with packaging material, wherein, as more desirable embodiments, the aseptic condition in the outer tube can be surely maintained even if the push and pull operations of the pusher are performed and, even if the pusher is pushed when not in use, a gasket does not move in tip direction and the arrangement of the pusher at the time of shipping can be stably maintained.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: July 25, 2006
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Hideaki Kito, Kouichi Tachikawa, Masaaki Kasai
  • Patent number: 7077824
    Abstract: A safety device for a syringe needle, which includes a guide and a slidable member having a first portion that is configured to be slid along the guide and a second portion having a formation for a needle, that facilitates the shielding of the sharp point within said formation. A non-reusable syringe, which includes a plunger having a first part with one or more followers and a second part housing a guide.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: July 18, 2006
    Assignee: African Ventures and Technology (Pty) Ltd.
    Inventor: Gysbert Albertus Meyer
  • Patent number: 7077829
    Abstract: A dialysis catheter comprising a first portion having a first diameter, an elongated distal portion having a second diameter smaller than the first diameter, and a transition region between the first portion and distal portion. A first longitudinally extending central lumen configured to deliver blood terminates in an opening in the distal portion. At least two independent longitudinally extending lumens are positioned radially of the first lumen, configured to withdraw blood from a patient, and terminate in a longitudinally directed opening in the transition portion.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: July 18, 2006
    Assignee: Rex Medical, L.P.
    Inventors: James F. McGuckin, Jr., Michael W. Paris, Paul Tashjian, Peter W. J. Hinchliffe
  • Patent number: 7077826
    Abstract: Syringes and methods of using are described which protect the syringe barrel cavity from contaminants. A first syringe is formed with a corrugated sheath or non-corrugated sheath which is positioned internal or external to the syringe barrel cavity. A second syringe is formed with a syringe barrel having a straight segment and a corrugated segment having the forward face of the plunger handle member molded to the rearward terminus of the corrugated segment of the syringe barrel. A third syringe is formed from mating syringe barrel and plunger member walls. The walls of the mating syringe barrel and plunger member are concentric and slide relative to each other while maintaining an enclosure around the plunger shaft. A fourth syringe is formed from inner and outer concentric syringe barrel walls mating with the walls of a plunger member. The mating walls are concentric and slide relative to each other while maintaining an enclosure around the plunger shaft.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: July 18, 2006
    Inventor: Robin Scott Gray
  • Patent number: 7074213
    Abstract: A dialysis catheter comprising a catheter body having a proximal portion, a distal portion, a first longitudinally extending central lumen configured to deliver blood, and at least three longitudinally extending lumens positioned radially of the central lumen and configured to withdraw blood from a patient. At least one blood delivery opening is formed in the distal portion of the catheter body and in fluid communication with the first lumen and configured for passage of blood therethrough. At least three blood withdrawal openings are formed in the outer wall of the catheter body, wherein each of the openings is in fluid communication with one of the at least three lumens and is configured for passage of blood from a patient.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: July 11, 2006
    Assignee: Rex Medical, L.P.
    Inventors: James F. McGuckin, Jr., Paul Tashjian, Michael W. Paris, Peter W. J. Hinchliffe
  • Patent number: 7074423
    Abstract: The present invention is directed to an osmotic engine useful in an osmotic delivery system for delivery of a beneficial agent in a controlled manner over a preselected administration period. By including a flowable engine comprising at least one osmotic agent and at least one fluid vehicle, the resulting osmotic engine reaches a zero order push power or push rate quickly and provides steady delivery of the beneficial agent.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: July 11, 2006
    Assignee: Alza Corporation
    Inventors: Pamela J. Fereira, Stephen A. Berry
  • Patent number: 7076285
    Abstract: An insertion tool for use in inserting a guide wire into a guide wire lumen of a catheter for use in a lumen of an endoscope. The insertion tool includes a main body having a main lumen and a funnel-shaped extension connected to and disposed atop the main body. The funnel-shaped extension having a funnel lumen. The funnel lumen has a top opening and a bottom opening. The funnel lumen tapering from the top opening to the bottom opening. The bottom opening positioned and sized to communicate with the guide wire lumen of the catheter such that, when the catheter is disposed in the main lumen, the guide wire may be easily inserted into the top opening of the funnel lumen and into the guide wire lumen of the catheter.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: July 11, 2006
    Assignee: SciMed Life Systems, Inc.
    Inventors: James E. Windheuser, James Yearick, Oscar Carrillo, Jr., Robert C. Allman, Fernando Alvarez de Toledo, Stephen C. Evans, Norman C. May
  • Patent number: 7070592
    Abstract: Devices are provided for medical diagnostics comprising a substrate; an array of reservoirs; one or more electrodes located at least partially inside the reservoirs; a plurality of discrete reservoir caps covering openings in the plurality reservoirs; control circuitry for selectively disintegrating or permeabilizing the reservoir cap over a reservoir opening; and, optionally, a diagnostic reagent in the reservoirs. Devices also are provided for the controlled delivery of molecules comprising a substrate; an array of reservoirs; a release system in the reservoirs comprising molecules for release; one or more electrodes attached to the substrate inside the reservoirs or to a surface outside of the reservoirs, wherein the electrodes are not reservoir caps; and means for applying an electric current or potential across the electrodes effective to activate release of the molecules from the reservoirs. The devices can be adapted for implantation for in vivo diagnostics or drug delivery.
    Type: Grant
    Filed: July 7, 2004
    Date of Patent: July 4, 2006
    Assignee: Massachusetts Institute of Technology
    Inventors: John T. Santini, Jr., Michael J. Cima, Robert S. Langer
  • Patent number: 7066905
    Abstract: Embodiments of the present invention are directed to a method and apparatus for accurate positioning of a dual balloon catheter. In one embodiment of the present invention, a first balloon provides an anchoring point. In one embodiment, the first balloon has protrusions to help secure its position. In one embodiment, once the first balloon is inflated, it provides a fixed position relative to which a second balloon is accurately positioned in the treatment region. In another embodiment, a second balloon imparts a radial force. In another embodiment, a second balloon imparts an axial force, using the first balloon as an anchor against which the force is applied. The force may be applied in a forward or a backward direction. In yet another embodiment, a second balloon imparts a rotational force, using the first balloon as an anchor against which the force is applied.
    Type: Grant
    Filed: November 13, 2002
    Date of Patent: June 27, 2006
    Inventors: James C. Squire, Elazer R. Edelman, Paul Tierstein
  • Patent number: 7063679
    Abstract: A renal flow system and method direct fluid into renal arteries from a location within the aorta. A renal flow assembly has a tapered tube that is adjustable between a radially collapsed condition for delivery to the location through a delivery sheath and a radially expanded condition that divides aortic flow into exterior and interior paths. The tube's wall is made from a sheet of flexible material, such as PTFE or ePTFE. Two, nickel-titanium rings radially support the tube's ends and are connected by a longitudinal spine support. A fluid delivery assembly injects drug to flow along the exterior flow path and the tubular wall directs the agent into the renal artery ostium. The tube's taper has localized shape for circumferential agent mixing to infuse both kidneys' renals. The flow assembly allows an interventional device, e.g. delivery catheter, to advance across the location while directing blood into the renals and perfusing downstream circulation.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: June 20, 2006
    Assignee: FlowMedica, Inc.
    Inventors: Mark Maguire, Richard Geoffrion
  • Patent number: 7060051
    Abstract: In one aspect of the invention a multi-balloon catheter, such as a double-balloon catheter, with coating comprising a hydrogel polymer on the exterior surface of the occlusion balloons is provided. The balloons may be inflated inside the lumen to occlude a plaque-affected segment of the lumen thereby forming a lumen space between the balloons, wherein this plaque-affected lumen segment may be treated with a biologically active agent. The presence of the coating can reduce de-nuding of healthy endothelial lumen tissue after contact with the inflated balloons during the occlusion. In another aspect of the invention, a method is provided for using a multi-balloon catheter having a coating comprising a hydrogel polymer for treating a plaque-affected lumen segment, the method reducing the subsequent de-nuding or injury to healthy endothelial tissue that is contacted by the balloon during occlusion.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: June 13, 2006
    Assignee: Scimed Life Systems, Inc.
    Inventor: Maria Palasis
  • Patent number: 7060055
    Abstract: The present invention is directed to a shieldable blood collection set as well as a needle assembly for use therein. The needle assembly includes a needle cannula having a puncture tip at a distal end thereof and a hub which supports the needle cannula. A hollow outer shield co-axially surrounds a distal end of the hub and has an inner surface which is in cooperating engagement with an outer surface of the hub. The hub includes a first tab extending outwardly at a position which is exposed from the outer shield, and the outer shield includes a second tab. The first tab and the second tab are configured such that opposing forces applied against the tabs cause the outer shield to move from a retracted position in which the puncture tip of the needle cannula is exposed, to an extended position in which the outer shield covers the puncture tip.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: June 13, 2006
    Assignee: Becton Dickinson and Company
    Inventors: Bradley M. Wilkinson, Volker Niermann
  • Patent number: 7062317
    Abstract: A device for facilitating transdermal passage of a substance through skin on the body of a subject is provided. The device preferably includes afcn electrode and a control unit. In a preferred embodiment, the control unit is adapted to drive the electrode to apply to the skin a current capable of ablating stratum corneum epidermidis of the skin, so as to facilitate transdermal passage of the substance. The control unit detects generation of at least one spark responsive to application of the current, and modifies a parameter of the current responsive to detecting the generation of the at least one spark.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: June 13, 2006
    Assignee: Transpharma Ltd.
    Inventors: Zohar Avrahami, Ze'ev Sohn