Patents Examined by Shuyi S Liu
  • Patent number: 10821220
    Abstract: A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: November 3, 2020
    Assignee: Haemonetics Corporation
    Inventors: Matthew Murphy, Dominique Uhlmann, Edward Powers, Michael Ragusa, Etienne Pagès
  • Patent number: 10814338
    Abstract: The botanical extraction and purification device described in this patent provide the ability to extract and purify botanical compounds from a diverse plant species through specially crafted process sequences that effectively reach the desired botanical component despite differences in botanical material types and unique differences in organic chemical characteristics. The technological package consists of two main processing centers; each is a combination of process features that can be personalized to effectively address unique extraction requirements. When combined, the extraction processes deliver capabilities in product throughput speed and product purity not available using previously available separation methods. The first component of this package is a CUP that transfers chemical compounds from botanical material into a solvent. The second component is an AISP. This device separates unwanted botanical compounds from the solvent, resulting in a relatively pure plant extract.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: October 27, 2020
    Assignee: Delta Separations, LLC
    Inventors: Benjamin Stephens, Scott Streeter
  • Patent number: 10807094
    Abstract: A device and method are provided to facilitate the handling of a volume or fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for receiving the volume or fluid. A stanchion has a first end received within the reservoir of the tube and a second end projecting from the open end of the elongated tube. In operation, the elongated tube is deposited in a first capsule having fluid therein. The first capsule is centrifuged such that the volume of fluid is received in a reservoir in the tube through the open end. The tube is removed from the first capsule and positioned in a second capsule such that the open end of the tube is spaced from a closed end of the second capsule. The second capsule is centrifuged such that the volume of fluid is expelled from the reservoir of the tube.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: October 20, 2020
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David J. Beebe, Jay W. Warrick, David J. Guckenberger, Jr.
  • Patent number: 10780445
    Abstract: A separator for centrifugally processing a flowable product includes a rotatable drum bounding a centrifuging chamber. The drum has a feeding and removal system having at least one feeding device and one or more removal devices composed of plastic or a plastic composite. An inner drum, composed of plastic or a plastic composite, is arranged in an outer supporting device of the drum. The feeding device and the one or more removal devices extend into the inner drum, do not rotate with the inner drum during operation, and are glued and/or welded to each other in such a way that the feeding device and the one or more removal devices are sealingly connected. The feeding and removal system has one or more grippers as the removal device, each of which one or two or more grippers has a disk segment and a shaft segment.
    Type: Grant
    Filed: November 27, 2015
    Date of Patent: September 22, 2020
    Inventors: Wilfried Mackel, Thomas Bathelt, Kathrin Quiter, Frank Taetz
  • Patent number: 10765971
    Abstract: Embodiments relate to systems, chambers, and methods for processing particles by washing, concentrating, and/or treating the particles. Some embodiments provide for the processing of cells that may be in a liquid medium (e.g., a liquid in which the cells were grown) and are processed by being washed and concentrated for later use in research or other therapies.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: September 8, 2020
    Assignee: Terumo BCT, Inc.
    Inventors: Timothy Michael Taga, Anne Baker Oram, Linda A. Taylor, Dennis J. Hlavinka
  • Patent number: 10758920
    Abstract: This invention is for a centrifugal separator comprised of a group formed by: a central feed chamber (10) fed by a feed pipe (20); a separation chamber (30) including a number of frustoconical disks (3); a first recovery chamber (11) in communication with a first liquid phase recovery pipe (21) and a gaseous phase recovery pipe (23); and a second recovery chamber (12) communicating with a second liquid phase recovery pipe (22), where the group is encompassed by a rotating envelope (1), where the central feed chamber (10) is in liquid fluid communication with the separation chamber (30), and in gaseous fluid communication with the first recovery chamber (11), where the separation chamber (30) is in fluid communication with the first and second recovery chambers where the centrifugal separator is encompassed by pressurizable stationary casing (4a, 4b).
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: September 1, 2020
    Assignees: PETROLEO BRASILEIRO S.A.-PETROBRAS, DELP Engenharia Mecânica S/A
    Inventors: Marcos Aurélio De Souza, Leonardo Dos Santos Pereira, Thiago Esteves Martins
  • Patent number: 10751731
    Abstract: The invention relates to a rotational unit (10) for a rotor of a dual centrifuge, said rotational unit having a bearing (14) and a rotational head (24) which is connected to the bearing (14), is mounted therein such that it can rotate about an axis of rotation and can be driven relative to the rotor by an additional rotational mechanism of the centrifuge, the rotational head (24) being detachably connected to the receiving unit (40, 80) for conjoint rotation, which receiving unit comprises a sample container receptacle (60, 70, 100, 110) for at least one sample container.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: August 25, 2020
    Inventors: Jovan Dobos, Klaus-Guenter Eberle, Ulrich Massing, Anke Lenz
  • Patent number: 10751732
    Abstract: There can be provided a bucket for a swinging rotor of a centrifugal separator that can be readily carried while ensuring the sealability at the time of a centrifugal treatment or the carriage operation. The bucket includes a bucket body (11) in a bottomed cylindrical shape, a cover main body (21) (cover), a packing (22) (seal member), and a pair of attachment mechanisms (34) configured to detachably attach the cover main body (21) to the bucket body (11). The cover main body (21) includes a lid portion (24) having clip fixing portions (31) (pressed portions) and configured to cover an opening (11a) of the bucket body (11), and a handle portion (25) formed integrally with the lid portion (24). The handle portion (25) is stretched between the pair of clip fixing portions (31). A handle concave portion (36) (hole) that opens toward the outside of the cover main body (21) and separates the lid portion (24) and the handle portion (25) is formed between the lid portion (24) and the handle portion (25).
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: August 25, 2020
    Inventor: Hideki Yoshida
  • Patent number: 10722881
    Abstract: The present invention relates to a centrifugation device, a centrifugation method, and a separation container.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: July 28, 2020
    Inventor: Jun Seok Lee
  • Patent number: 10711239
    Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: July 14, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: John E. Nash, William T. Fisher, Gino Bradica
  • Patent number: 10697957
    Abstract: A method of evaluating a patient's hematocrit includes collecting a sample of blood in a capillary tube, and placing the capillary tube into a centrifuge having a rotor. The centrifuge has base with a center axis and a manual rotation member. The rotor spins in response to the manual rotation member being pulled by an operator, and the rotor is coupled for rotation to the base. The rotor including a plurality of microfluidic channels. The sample of blood is separated with the centrifuge into a red blood cell portion and a plasma portion in the microfluidic channels. A diagnosis image is provided including a base line indicia, a lower normal line indicia, an upper normal line indicia and a 100 % level line indicia. The capillary tube is placed against the diagnosis image with the bottom end placed adjacent the base line indicia.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 30, 2020
    Inventors: Michael Rust, Joseph T. Papu, Andrew W. Browne
  • Patent number: 10688503
    Abstract: The present invention relates to a hybrid rotor for a centrifuge, in particular a laboratory centrifuge, comprising a rotor base body with a receptacle side and a drive side, means for fixing a drive shaft for rotating the hybrid rotor about a rotation axis (R), at least two receptacles with an insertion opening for centrifuge containers arranged on the receptacle side of the rotor base body, a rotary bearing for rotatably mounting a swinging container being formed on at least one receptacle and a fixed bearing for fixedly mounting a fixed angle container being formed on at least one receptacle. The present invention further relates to a set for a centrifuge, comprising a hybrid rotor and at least one fixed angle container. Furthermore, the present invention relates to fixed angle container for use in a hybrid rotor or in a set.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: June 23, 2020
    Assignee: Thermo Electron LED GmbH
    Inventors: Sebastian Henne, Sven Stephan
  • Patent number: 10675640
    Abstract: A centrifugal separator is configured for cleaning of crankcase gases from an internal combustion engine. The centrifugal separator includes a rotor rotatably arranged inside a stationary housing. The stationary housing includes an inlet for crankcase gases, a gas outlet, and a liquid outlet. The rotor includes a stack of separation discs, each separation disc of the stack of separation discs having a center axis, an inner surface, and an outer surface. A circumferential inner end surface extends between the inner surface and the outer surface. The circumferential inner end surface of at least one separation disc of the stack of separation discs includes a substantially flat first surface portion extending at an angle of at least 20 degrees to the center axis.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: June 9, 2020
    Inventor: Mats-Örjan Pogén
  • Patent number: 10654049
    Abstract: The present disclosure relates to a centrifugal separator (1), which comprises a rotatable drum (5) having a wall (50), an annular chamber (7) defined along the longitudinal axis (49) of the rotatable drum (5) in a portion adjoining to the wall (50), wherein a mixture of substances in the liquid phase and in the solid phase is movable longitudinally through the annular chamber (7), and a discharging station (13) for discharging the solid phase. The discharging station (13) comprises a vibrating unit (300) for agitating the solid phase. The vibrating unit (300) comprises a half-drum (302) and a vibrating device (304) adapted to vibrate the half-drum (302).
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: May 19, 2020
    Inventors: Leonardo Renzo Vicentini, Albert Walraven
  • Patent number: 10639649
    Abstract: A feedback control method accounts for noise emissions of a centrifuge for the operation of a centrifuge, in particular a separator or a decanting centrifuge, for the centrifugal processing of a product, in particular for clarifying a product and/or for separating a product into different liquid phases using the drum.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: May 5, 2020
    Inventors: Markus Fleuter, Wilfried Mackel
  • Patent number: 10639650
    Abstract: A method for monitoring, controlling, and/or regulating the operation of a centrifuge, in particular a separator, during the centrifugal processing of a product, in particular when clarifying a product and/or when separating a product into different liquid phases. The centrifuge has a drum which can be rotated by a drive spindle, a drum mounting, and a drive motor. Force measurements are performed using one or more force sensors and analyzed, and an output is provided in the event of a deviation from a specified behavior and/or the analyses are used for or during the control and/or regulation of the operation of the centrifuge.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: May 5, 2020
    Inventors: Wilfried Mackel, Kathrin Quiter, Thomas Bathelt
  • Patent number: 10618060
    Abstract: Embodiments are directed to methods and apparatuses for ensuring that mechanisms that are used to position components of an apheresis machine are not broken as a result of rotation of a centrifuge. In embodiments, a safety mechanism is provided that contacts components of the centrifuge and pushes them into a position to ensure that they do not break when the centrifuge is operated at high rpm.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: April 14, 2020
    Assignee: Terumo BCT, Inc.
    Inventor: Luke Ryan Noffsinger
  • Patent number: 10618061
    Abstract: A support structure for a rotation driving system having a ball balancer includes: a motor having a rotational shaft coupled to a rotational shaft of a rotor; the ball balancer provided on the rotor to reduce oscillating motion of the rotor; and a support part for coupling the motor to a housing, wherein the motor is coupled to the housing via an elastic member on a line in one direction (x-axis) perpendicular to an axial direction (z-axis) of the rotational shaft of the motor, and the motor is allowed to swing about the x-axis due to elastic deformation of the elastic member.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: April 14, 2020
    Assignee: Tomy Kogyo Co., Ltd.
    Inventor: Soichiro Matsushima
  • Patent number: 10603646
    Abstract: A lab stirrer comprises a housing, a stirring shaft rotatably supported about an axis in the housing and a drive to drive the stirring shaft to make a rotary movement about the axis. A blocking device is provided to block the stirring shaft against a rotation about the shaft axis.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: March 31, 2020
    Assignee: Hans Heidolph GmbH
    Inventors: Kai Bretschneider, Dirk Seifferth
  • Patent number: 10603665
    Abstract: A system and associated method for concentrating and separating components of different densities from fluid containing cells using a centrifuge includes a container defining a cavity for receiving the fluid. The container has a top, a sidewall extending from the top, and a bottom disposed opposite the top and in sealing engagement with the sidewall. An insert is slidably disposed in the cavity of the container and defines a lumen through the insert. The lumen, which includes a hole and a funnel-shaped upper portion in fluid communication with the hole, forms an open fluid path between opposite ends of the insert. The insert has a density such that upon centrifugation a selected component of the fluid resides within the lumen. A container port is disposed in the top of the container to transfer the fluid into the container and to withdraw a fluid component other than the selected component from the container.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: March 31, 2020
    Assignee: EndoCellutions, Inc.
    Inventors: Andy H. Levine, John C. Meade, Neil Tischler, Jeffrey R. Chabot, Andrew McGillicuddy, Neil F. Duffy, Jr.