Patents Examined by Susan E. Fernandez
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Patent number: 11786568Abstract: Provided is Lactobacillus kefiri MSR101, having the accession member being CGMCC No. 17506. The strain has acid resistance, bile salt resistance, resistance to phenol, antibiotic resistance, antioxidant activity, cell surface hydrophobicity, adhesion to intestinal epithelial cells, and a cholesterol-lowering function.Type: GrantFiled: March 18, 2020Date of Patent: October 17, 2023Assignee: SHENZHEN UNIVERSITYInventors: Liqing Zhao, Muhammad Shahid Riza Rajoka
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Patent number: 11773535Abstract: The present specification discloses papermaking additive compositions, articles of manufacture, containers or kits comprising such compositions, and methods and uses to increase separation of cellulose fibers from a pulp, to remove one or more impurities and/or one or more contaminates from a pulp and/or a paper material and to remove an ink from a pulp and/or a paper material.Type: GrantFiled: December 27, 2019Date of Patent: October 3, 2023Assignee: Neozyme International, Inc.Inventors: Parker Dale, Parker David Dale
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Patent number: 11772996Abstract: The present invention provides a process for the treatment of sewage sludge with enzymes, which process comprises treating a sewage sludge resulting from the treatment of municipal or industrial waste water with a composition comprising a fermentation supernatant product from a Saccharomyces cerevisiae culture and a non-ionic surfactant, wherein said fermentation supernatant product is free of active enzymes, at conditions suitable for generating said active enzymes from said sewage sludge in situ.Type: GrantFiled: December 27, 2019Date of Patent: October 3, 2023Assignee: Neozyme International, Inc.Inventors: Parker Dale, Parker David Dale
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Patent number: 11771091Abstract: The present specification discloses plant agent compositions, articles of manufacture, containers or kits comprising such compositions, and methods and uses to control a causal agent of a plant disease or increasing plant growth and/or fruit production.Type: GrantFiled: December 27, 2019Date of Patent: October 3, 2023Assignee: Neozyme International, Inc.Inventors: Parker Dale, Parker David Dale
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Patent number: 11752168Abstract: A skin care composition is disclosed comprising at least one exopolysaccharide (EPS) originating from a microbial mat, the EPS being in a concentration of about 0.001% w/w to about 1.5% w/w of the composition. Uses and methods of use thereof. In specific embodiments, the EPSs are derived from microorganisms isolated from microbial mats found in French Polynesia. The composition is useful in reducing signs of skin aging and environmental damage by altering skin cell metabolism and improving hydration.Type: GrantFiled: May 12, 2021Date of Patent: September 12, 2023Assignee: LUCAS MEYER COSMETICS CANADA INC.Inventors: Estelle Loing, Sandrine Briatte, Patrice Dionne, Martin Beaulieu, Xavier Moppert, Laurent Richert, Catherine Vayssier
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Patent number: 11753657Abstract: Ear corn is picked from corn fields by ear corn harvesters and transported to a central shelling station associated with an ethanol manufacturing facility. Shelled corn from the central shelling station is processed into ethanol at the ethanol manufacturing facility, and corn cobs from the central shelling station are burned to provide process heat for the ethanol manufacturing process. Energy is conserved and costs are reduced during the picking and shelling of the ear corn and by the burning of cobs for process heat.Type: GrantFiled: November 18, 2020Date of Patent: September 12, 2023Inventor: Alvin D. Shulman
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Patent number: 11724293Abstract: The present invention relates to compositions and methods for the remediation of contaminated solids and liquids. In particular, embodiments of the present invention relate to the bioremediation of solids and liquids by a composition comprising a biocatalyst or mixture of biocatalysts. The present invention also relates to methods for producing the bioremediation compositions and methods for applying the bioremediation compositions to contaminated sites, including treatment, storage, and disposal facilities, as well as various contaminated water sources, such as aquifers and reservoirs.Type: GrantFiled: January 15, 2021Date of Patent: August 15, 2023Inventors: Todd Franssen, Carla Franssen
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Patent number: 11709169Abstract: The present invention is related to novel methods for identifying a population of subjects that are at risk for developing of atopic allergic diseases, such as atopic dermatitis, and to the prevention and treatment of these allergic diseases.Type: GrantFiled: February 7, 2018Date of Patent: July 25, 2023Assignee: National Jewish HealthInventors: Donald Y. M. Leung, Elena Goleva, Evgeny Berdyshev
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Patent number: 11649472Abstract: The disclosure provides methods using mixed substrate cofeeding for bioproduct synthesis, which enables faster, more efficient, and higher yield carbon conversion in various organisms.Type: GrantFiled: June 29, 2018Date of Patent: May 16, 2023Assignee: Massachusetts Institute of TechnologyInventors: Junyoung Park, Nian Liu, Gregory Stephanopoulos
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Patent number: 11634702Abstract: A method for activating a cell-signaling pathway of interest in a cell, including applying a time-modulated localized alternating current electrical field to the cell, wherein the amplitude and frequency of the localized alternating current electrical field is selected to activate the cell signaling pathway of interest, thereby activating the cell signaling pathway.Type: GrantFiled: November 5, 2019Date of Patent: April 25, 2023Assignees: Arizona Board of Regents on behalf of Arizona State University, The Regents of the University of CaliforniaInventors: Quan Qing, John Albeck, Liang Guo, Min Zhao, Houpu Li
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Patent number: 11622560Abstract: The invention belongs to the field of microbes and specifically relates to a myroides odoratimimus biocontrol strain for efficiently degrading aflatoxin and an application thereof. A myroides odoratimimus biocontrol strain 3J2MO is preserved at the China Center for Type Culture Collection (referred to as CCTCC) on Jun. 13, 2017 with preservation number CCTCC No. M 2017329. The myroides odoratimimus biocontrol strain of the invention can effectively degrade aflatoxin and may be configured to degrade aflatoxin and treat aflatoxin pollution of food crops.Type: GrantFiled: May 29, 2020Date of Patent: April 11, 2023Assignee: OIL CROPS RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCESInventors: Qi Zhang, Peiwu Li, Tong Wang, Xiaoxia Ding
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Patent number: 11618895Abstract: The present invention relates to a method for extracting nucleic acids from a biological sample, and the extraction method presents a novel method for effectively extracting nucleic acids. When nucleic acids are extracted from biological samples in the related art, various impurities present in the biological samples are not properly removed, such that the purification rate is low, but the present invention provides a method for extracting nucleic acids from a biological sample of which the bacteria, virus and nucleic acid recovery rates are enhanced, by adding a surfactant and a sodium sulfate (Na2SO4) solution in a biological sample disruption step and a purification step, thereby enabling pathogens to be detected more sensitively and accurately.Type: GrantFiled: August 24, 2018Date of Patent: April 4, 2023Assignee: CT BIO CO., LTDInventors: Jun Hong Min, Chang Yoon Baek
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Patent number: 11567080Abstract: New use of ADAMTS13 in the clinical filed is provided. The use of ADAMTS13 as a biomarker for monitoring the onset of liver damage, hepatic ischemia/reperfusion injury or the liver function after liver transplantation: a method of testing liver damage, a method of testing hepatic ischemia/reperfusion injury, or a method of testing the liver function after liver transplantation, each of the methods comprising measuring or monitoring the ADAMTS13 activity in a sample from a mammal; an agent for treating diseases selected from the group consisting of liver damage, hepatic ischemia/reperfusion injury and hepatic dysfunction after liver transplantation, which comprises ADAMTS13 or a mutant of ADAMTS13 as an effective ingredient.Type: GrantFiled: January 6, 2017Date of Patent: January 31, 2023Assignees: KYOTO UNIVERSITY, KM BIOLOGICS CO., LTD.Inventors: Koichiro Hata, Shinji Uemoto, Hirofumi Hirao, Toyonari Kubota
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Patent number: 11566225Abstract: Systems and methods for processing biological fluids are disclosed. The systems and methods use a reusable hardware unit and a disposable fluid processing circuit that mounts onto the reusable hardware unit. The system and method, under the direction of a pre-programmed controller allow for automatically, opening one or more flow paths to effect addition of one or both parts of an additive solution to a biological fluid component.Type: GrantFiled: October 3, 2014Date of Patent: January 31, 2023Assignee: Fenwal, Inc.Inventors: Daniel Lynn, Katherine Radwanski
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Patent number: 11560544Abstract: The present invention concerns a process for isolating an archaeon of the order of commensal clade Methanomassiliicoccales, the use of a culture and/or isolation medium comprising a sterile extract of a bacterial culture of a bacterium of genus Eggerthella, for the isolation and/or culture of an archaeon of the order of commensal clade Methanomassiliicoccales, and a pure, isolated archaeon Methanomethylophilus alvus Mx-05. It also concerns a culture method of an archaeon of the order of commensal clade Methanomassiliicoccales.Type: GrantFiled: November 30, 2018Date of Patent: January 24, 2023Assignees: LESAFFRE ET COMPAGNIE, UNIVERSITÉ CLERMONT AUVERGNE, INSTITUT DE RECHERCHE POUR LE DÉVELOPPMENTInventors: Wajdi Ben Hania, Jean-François Brugere, Marie-Laure Fardeau, Bernard Ollivier
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Patent number: 11542531Abstract: According to one embodiment, a microcapsule for selective catalysis of gases, the microcapsule comprising: a polymeric shell permeable to one or more target gases; and at least one biocatalyst disposed in an interior of the polymeric shell. In more embodiments, methods of forming such microcapsules include: emulsifying at least one biocatalyst in a polymer precursor mixture; emulsifying the polymer precursor mixture in an aqueous carrier solution; crosslinking one or more polymer precursors of the polymer precursor mixture to form a plurality of microcapsules each independently comprising: a polymeric shell permeable to one or more target gases; and at least one biocatalyst disposed in an interior of the polymeric shell. In further embodiments, corresponding methods of using the inventive microcapsules for catalyzing one or more target gases using include: exposing a plurality of the biocatalytic microcapsules to the one or more target gases.Type: GrantFiled: January 20, 2017Date of Patent: January 3, 2023Assignee: Lawrence Livermore National Security, LLCInventors: Sarah Baker, Joshuah K. Stolaroff, Congwang Ye
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Patent number: 11528911Abstract: Compositions comprising microbiological strains and cultures and methods of use thereof are provided herein. Certain strains, cultures, and compositions thereof are useful for the control of head blight disease, for example, of various crop plants. Biological control compositions, and methods of use thereof to prevent, inhibit or treat the development of plant pathogens or disease and for preserving plant yield, are also provided.Type: GrantFiled: July 17, 2019Date of Patent: December 20, 2022Assignee: MONSANTO TECHNOLOGY LLCInventors: Christopher J. Grandlic, Wayne A. Green, Janne S. Kerovuo, Ryan T. McCann
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Patent number: 11510995Abstract: Disclosed is a nanoparticle system consisting of a polymer support or substrate in the form of nanoparticles to which a hydrolase enzyme able to degrade hyaluronic acid and one or more biologically and/or pharmacologically active molecules are covalently bonded, its preparation process and its uses in the diagnostic, prognostic and therapeutic fields.Type: GrantFiled: December 20, 2016Date of Patent: November 29, 2022Assignees: FIDIA FARMACEUTICI S.P.A., NANOGETIC S.L.Inventors: Rosario Maria Sanchez Martin, Salvatore Pernagallo, Juan Diego Unciti Broceta, Luciano Messina, Susanna Vaccaro, Laura Pilotto
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Patent number: 11485994Abstract: Methods and systems for using encapsulated microbubbles to process biological samples are disclosed. According to one aspect, a method for using encapsulated microbubbles to process a biological sample includes creating a mixture comprising encapsulated microbubbles mixed with a biological sample and adding activation energy to the mixture to cause at least some of the microbubbles to oscillate or burst and thereby process the sample, including effecting cell lysis, shearing DNA, and/or performing tissue dispersion.Type: GrantFiled: May 25, 2018Date of Patent: November 1, 2022Assignee: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILLInventors: William Perry Janzen, Samantha Gail Pattenden, Chatura Nadisha Jayakody, Jason Eric Streeter, Paul Alexander Dayton, Cameron Champion Wood, Siddharth Kaup Shenoy
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Patent number: 11479802Abstract: Screening methods as well as kits for identifying modulators of hydroxysteroid (17-beta) dehydrogenase (HSD17B) family member proteins, such as HSD17B13, are provided. The methods comprise screening molecules for their capacity to modulate the HSD17B family member protein, including inhibiting the HSD17B family member protein, as measured by substrate depletion, product concentration from the HSD17B family member protein substrate conversion or NADH concentration, levels of labeled substrate, luciferin light emission, or combinations thereof. Inhibitors of HSD17B family member proteins identified through the screening methods may be used to treat liver diseases, disorders, or conditions in which the HSD17B family member protein plays a role.Type: GrantFiled: March 6, 2018Date of Patent: October 25, 2022Assignee: Regeneron Pharmaceuticals, Inc.Inventors: Panayiotis Stevis, David Esopi, Jesper Gromada, Jorge Haller, Yashu Liu, Andrew Murphy, William Olson