Abstract: In various embodiments, a first classification assigned to a periodic component of an electrical waveform that represents electrical activity in a patient's heart may be identified. A corresponding periodic component of a hemodynamic waveform that represents hemodynamic activity in the patient's cardiovascular system may be analyzed. The corresponding periodic component may be causally related to the periodic component of the electrical waveform. Based on the analysis, the previously-assigned classification may be assigned to the corresponding periodic component of the hemodynamic waveform in response to a determination, based on the analyzing, that the previously-assigned classification also applies to the corresponding periodic component. In a database of hemodynamic templates, a hemodynamic template associated with the previously-assigned classification may be updated to include one or more features of the corresponding periodic component of the hemodynamic waveform.

Abstract: The invention provides, in various embodiments, aspects of soft tissue anchors, adjustable length/tension slings, interconnects between slings and soft tissue anchors, delivery devices and systems for implanting supportive slings, and methods relating to anchoring, 5 adjusting and implanting supportive slings.

Abstract: Disclosed herein is an immersive distraction apparatus including an attachment portion including an engagement element and a front plate having two cut outs fitting lenses therein and a base portion coupled with the attachment portion having a display aperture sized to receive a device. The immersive distraction apparatus mountable on a surgical head frame using one or more connectors such that an immersive distraction therapy can be provided to a patient undergoing surgery via a virtual reality environment.

Abstract: Embodiments of the present disclosure are directed to radiotherapy systems. An exemplary radiotherapy system may comprise a radiotherapy output configured to deliver a charged particle beam to a patient. The system may also comprise a detector array. The detector array may have an axis that extends parallel to an axis along which the charged particle beam is delivered by the radiotherapy output. The detector array may comprise a plurality of detectors configured to detect a magnetic field generated by the charged particle beam during delivery of the charged particle beam from the radiotherapy output.

Abstract: In some aspects, the present invention provides surgical procedures that comprise applying compositions into and/or onto tissue, including supporting tissues (e.g., ligaments, connective tissue, muscles, etc.) for pelvic organs, among other tissues. In other aspects, the present disclosure pertains to compositions that are useful for performing such procedures. In still other aspects, the present disclosure pertains to kits that are useful for performing such procedures.

Abstract: Some embodiments relate to imageable radioisotopic microspheres. In some embodiments, the imageable microspheres are radiolabeled with imageable radioisotopes. In some embodiments, the imageable radioisotope is directly coupled to a surface of a substrate of the microsphere. In some embodiments, the imageable microspheres can be used as surrogate particles to predict the distribution of therapeutic microspheres comprising radiotherapeutic isotopes.

Abstract: Targeted and individualized methods are provided herein for determining specific treatment sites based on an individual patient. Embodiments described herein may use functional and/or structural connections to create brain mapping of the patient and/or control groups having the same metrics as the patient, and combinations thereof in determining target locations for stimulation treatment.

Abstract: A cuff for use an as artificial sphincter includes an inflatable chamber and a backing. The inflatable chamber includes opposing inside and outside surfaces and inflated and deflated states. The backing is adjacent the outside surface of the chamber. The inside surface of the chamber includes two or more grooves that define the location of fold lines of the inflatable chamber when the inflatable chamber is in the inflated state. The inflatable chamber and backing are configured to surround a duct of a patient with the inside surface of the chamber facing the duct and the grooves extending substantially parallel to the duct.

Abstract: A mesh deployment device is configured to place a surgical mesh on tissue retro muscularly. In particular, the mesh deployment device includes an arm assembly that is transitionable between a retracted configuration, in which, stationary and covering arms are in superposed relation such that the surgical mesh is supported by the supporting arm therebetween, and a deployed configuration, in which, the stationary, covering, and supporting arms are circumferentially spaced apart to support the surgical mesh thereon.

Abstract: Actuator (1) for a medical device (100), comprising an electromotor, a mechanical transmission, and magnetic coupling means arranged for transmitting a mechanical torque from the electromotor to the mechanical transmission when said electromotor is powered by an energy source, wherein said electromotor and a first part of the magnetic coupling means kinematically linked to the electromotor are arranged and hermetically sealed in a first casing module, and wherein said mechanical transmission and a second part of the coupling means kinematically linked to said mechanical transmission are arranged in a second casing module, said first and second casing modules comprising each complementary fastening means such that said first and second casing modules can be removably connected to each other in such a way that said first and second parts of the magnetic coupling means magnetically couple together upon connection of said first and second casing modules.

Abstract: Disclosed are enclosures for establishing a sterile environment over a patient for a medical procedure, as well as systems and methods thereof. An enclosure can include an expandable portion of a barrier separating a sterile environment inside of the enclosure from a non-sterile environment outside of the enclosure and a patient-interfacing portion of the barrier. The enclosure can also include a support system coupled to the patient-interfacing portion of the barrier in some embodiments. The patient-interfacing portion of the barrier can include one or more fenestrations for placement directly over one or more areas of interest of the patient, as well as for access to the areas of interest from within the sterile environment. When present, the support system can flank the fenestration. The support system is configured to support the enclosure on a surface when placed over an appendage of the patient or a main body of the patient.

Abstract: An inflatable penile prosthesis can include, a reservoir, an inflatable member and a pump assembly. The pump assembly can include at least one valve comprising an entry portion, a middle portion, an exit portion, and exit tube interface, and a valve member. The exit portion can include a first landing portion including an interior portion, the interior portion of the first landing portion being semicircular about a longitudinal exit axis, the longitudinal exit axis extending through a center of the exit portion parallel to a direction that an exit tube interface extends from the exit portion, and a first channel portion adjacent to the first landing portion and including an interior portion, the interior portion of the first channel portion being farther from the longitudinal exit axis than the interior portion of the first landing portion.

Abstract: A device and method for inducing sleep, improving blood circulation, and correcting autonomous imbalances. The device includes a heat exchange member mounted on top of housing, the heat exchange member can receive a neck of a user and apply alternate hot and cold stimuli to the neck. The hot and cold stimuli improve blood circulation and correct the autonomous imbalances. The device includes a drive module and a heat sink to quickly switch from hot to cold.

Abstract: Brachytherapy templates and template holders can be adjustable relative to a patient's anatomy. One template includes a disposable portion with an aperture layer that includes first apertures and a patient contact layer that includes an adhesive on a surface thereof. The patient contact layer is formed from a flexible material. The template also includes a reusable portion that includes aperture plates. A locking mechanism can lock catheters firmly in place. One template holder includes a template compartment retainer constructed to hold a brachytherapy template, and a perineum attachment component is connected to the template compartment retainer by a connecting portion. The perineum attachment component includes a perineum attachment portion formed from a flexible material.

Abstract: A system for estimating a dose from a radiation therapy plan includes a memory that stores machine-readable instructions and a processor communicatively coupled to the memory, the processor operable to execute the instructions to subdivide a representation of a volume of interest into voxels. The processor also determines distances between a planned radiation field origin and each respective voxel. The processor further computes geometry-based expected (GED) metrics based on the distances, a plan parameter, and a field strength parameter. The processor sums the metrics to yield an estimated dose received by the volume of interest from the planned radiation field.

Abstract: An apparatus for use in clinical environments. The apparatus includes a trocar, having a cannula with a proximal end and a distal end. The cannula defines a lumen therethrough that extends from the proximal end to the distal end. A proximal port at the proximal end provides access to an interior of the lumen from an exterior of the cannula. Further, a distal port at the distal end provides access to the interior of the lumen from the exterior of the cannula. At least one trocar antenna is physically coupled to the trocar and is positioned and oriented to provide wireless communications coverage to at least a portion of an interior of the lumen and to any wireless communications transponders that pass through the lumen of the cannula.

Abstract: The disclosure pertains to a strontium-90 sealed radiological or radioactive source, such as may be used with treatment of the eye or other medical or industrial processes. The sealed radiological source includes a radiological insert within an encapsulation. The encapsulation may include increased shielding in the center thereof.

Abstract: A method of using at least one implantable mesh extension for repairing a tissue defect or reconstructing tissue, wherein the mesh extension is comprised of a mesh having a width and a length extending between a first end and a second end, includes passing the first end of the mesh extension through tissue adjacent to the tissue defect or tissue to be reconstructed at least once and then passing the first end of the mesh extension through a portion of the mesh. The mesh extension is then pulled to create a first self-locking stitch to anchor the mesh extension to the adjacent tissue so as to immediately resist high tension.

Abstract: A method of galvanic vestibular stimulation (GVS) may include delivering an electrical signal via transdermal electrical stimulation using a plurality of electrodes connected to a patient. The electrical signal may include an amplitude and a carrier frequency. The method may include modulating at least one of the amplitude and the carrier frequency based on a modulation waveform to modulate the electrical signal, the modulation waveform may include a modulation frequency that is less than the carrier frequency.

Abstract: Apparatuses for use in straw phonation are provided herein. These apparatuses are typically reusable. Kits comprising these apparatuses are also provided which allow the apparatuses to be stored safely for repeated use throughout the day as required. Additionally, the present disclosure is related to methods of practicing straw phonation with the apparatuses described herein.