Patents Examined by Theresa A. Trembley
  • Patent number: 5039494
    Abstract: In order to render harmless the aerosol laden smoke stream which results from the operation of medical lasers in or on mammalian bodies, the stream is moved in a closed circuit maintained at negative pressure. The circuit includes a container of sterilizing fluid to retain and destroy the larger aerosol particles and downstream of that container a chamber having an oxygen enriched atmosphere which is heated to a temperature sufficient to incinerate the remaining aerosol particles which are too small to filter. The thus purified stream is then cooled and released to ambient.
    Type: Grant
    Filed: January 29, 1990
    Date of Patent: August 13, 1991
    Inventors: Juan N. Martin, John K. Martin
  • Patent number: 5039492
    Abstract: An optical pH sensor and a gas sensor utilizing the pH sensor. The pH sensor includes an indicator whose absorbance is a function of the concentration of hydronium ions in a media surrounding the indicator. Light transmitted and reflected through the indicator of the sensor undergoes an absorption that is characteristic of the concentration of the hydrogen ion. The pH sensor can be used as to sense the concenration of a gas in a sample by surrounding the indicator with a liquid or liquid-containing media that changes pH as it is exposed to the gas, and separating the indicator and liquid or liquid-containing media from the gas with a membrane that is permeable to the gas to be measured. A measuring system used with the sensors transmits coherent radiation to the sensor through an optical fiber, separates the radiation returning from the sample into two wavelength bands, and digitally samples the photocurrents produced within the two wavelength bands.
    Type: Grant
    Filed: January 27, 1989
    Date of Patent: August 13, 1991
    Assignee: MetriCor, Inc.
    Inventors: Elric W. Saaski, David A. McCrae, James C. Hartl, Dale M. Lawrence, Roger A. Wolthuis
  • Patent number: 5039491
    Abstract: An oxygen sensor contains an indicator whose change in absorption is a function of the concentration of oxygen in a sample bathing the indicator. Light transmitted and reflected through the indicator of the sensor undergoes an absorption that is characteristic of the concentration of oxygen. The indicator is a viologen whose absorption returns to a steady-state value after it has been subjected to a pulse of short-wavelength light. The rate at which the absorption returns to the steady-state value is a function of the concentration of oxygen bathing the viologen indicator. A measurement system for use with the pO.sub.2 sensor causes a short-wavelength flash to be sent to the sensor and thereafter monitors the time-varying absorption of the sensor to measure the oxygen content of the sample bathing the viologen indicator.
    Type: Grant
    Filed: January 27, 1989
    Date of Patent: August 13, 1991
    Assignee: MetriCor, Inc.
    Inventors: Elric W. Saaski, David A. McCrae, Dale M. Lawrence
  • Patent number: 5035865
    Abstract: A blood sample collecting device includes a vacuum blood sampling chamber having a blood container disposed therein, and a vacuum pump for evacuating the vacuum blood sampling chamber to collect a blood sample into the blood container under a vacuum developed in the vacuum blood sampling chamber. The amount of collected blood in the blood container, and the vacuum in the vacuum blood sampling chamber is lowered below a preset pressure on the condition that a rate of increase in the measured amount of collected blood does not reach a predetermined normal rate of increase.
    Type: Grant
    Filed: May 15, 1989
    Date of Patent: July 30, 1991
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Fumiaki Inaba, Satoshi Inoue
  • Patent number: 5035863
    Abstract: A surface plasmon resonance (SPR) sensor is adapted for biochemical and similar testing on large area samples such as the gel of an electrophoresis apparatus. The gel is sandwiched between a pair of plates. One of the plates is of transparent material and, sandwiched between itself and the gel is a metal layer of a mosaic of silver dots. Light from a source is directed via a reflector and undergoes total internal reflection at the interfacce between the transparent plate and metal layer. The reflected light is passed via another reflector to a light detector. The equipment is arranged so that SPR occurs at the metal layer, which resonance is critically dependent upon the refractive index of the gel. The structure including the light source and detector, together with reflectors is caused to scan across the gel surface to enable a two-dimensional representation of the changes in refractive index across the gel to be built up. This enables the progress of sequencing to be monitored.
    Type: Grant
    Filed: May 10, 1989
    Date of Patent: July 30, 1991
    Assignee: Amersham International plc
    Inventors: Martin F. Finlan, Michael A. W. Brady
  • Patent number: 5030419
    Abstract: The presence of certain chemicals on the emitting surface of the surface-derivatized photoluminescent semiconductor alters the characteristics of radiation emitted from said surface. This alteration is used to indicate the presence of those chemicals in the environment.
    Type: Grant
    Filed: June 14, 1990
    Date of Patent: July 9, 1991
    Inventors: Arthur B. Ellis, Elizabeth R. M. Luebker, Larry K. Leung, George C. Lisensky
  • Patent number: 5028395
    Abstract: Active chemical sensor with optical fiber and its production process.The chemical sensor according to the invention makes it possible to measure a given quantity or magnitude of a fluid. It has a chemical reagent suitable for the measurement and for reacting with the fluid, a support means (20a, 28) for the reagent and a single optical fiber (20) for supplying light to the reagent and recovering the light reflected by the reagent, said sensor being characterized in that the support means incorporates a vinyl imidazole polymer or copolymer film (28) in which the reagent is immobilized, said polymer being in particular directly grafted on to one of the ends (20a) of the optical fiber (20).
    Type: Grant
    Filed: July 16, 1990
    Date of Patent: July 2, 1991
    Assignees: Commissariat a l'Energie Atomique, Photonetics
    Inventors: Bernard Sebille, Bruno Biatry, Gilbert Boisde
  • Patent number: 5023053
    Abstract: A surface plasmon resonance (SPR) sensor in which a membrane is used to enable the sensitive material to be readily changed to enable tests to be carried out on a sequential basis simply by moving or changing the membrane. In one embodiment, the membrane takes the form of a continuous film (24) which lies against and is moveable across by means not shown, a transparent plate (17) which forms part of the SPR sensor. The film (24) comprises a layer (31) of flexible transparent material to which is applied a thin layer (32) of metal such as silver. Applied to layer (32) is a layer (33) of sensitive material. The final layer (34) is a preformed layer of hydrophyllic plastics material which incorporates troughs (37) and passageways (35,38) for the transfer of sample across the sensitive layer. Light from a laser (not shown) is subject to total internal reflection at the interface between the transparent layer (31) and metal layer (32), and the reflected light is collected by a light detector (not shown).
    Type: Grant
    Filed: May 22, 1989
    Date of Patent: June 11, 1991
    Assignee: Amersham International PLC
    Inventor: Martin F. Finlan
  • Patent number: 5021217
    Abstract: A multipipet designed to allow a plurality of cylinders to be supported by a supporting member in such a manner that each cylinder is individually oscillatable sideward relative to said supporting member. A multipipet designed to allow a plurality of plungers and a plurality of cylinders to be accommodated in a single housing and a gripping body to be attached to said housing through thread engagement.
    Type: Grant
    Filed: June 19, 1989
    Date of Patent: June 4, 1991
    Assignee: Nichiryo Co., Ltd.
    Inventor: Yuju Oshikubo
  • Patent number: 5021218
    Abstract: An apparatus is provided to identify, index and display slides having a specimen thereon, and to secure the slides so as to protect biopsy material and similar specimens retained thereon. There is also provided a slide carrier to hold slides in spaced relation while slides are collectively immersed or wetted, thereby saving considerable time during the processing of the slides by laboratory personnel. The slides are marked by a permanent and unique code which is visible while the slides are retained within the slide carrier container.
    Type: Grant
    Filed: January 19, 1990
    Date of Patent: June 4, 1991
    Assignee: DLP, Inc.
    Inventors: Richard E. Davis, Michael D. Glant
  • Patent number: 5019346
    Abstract: A drain sanitizing article (9) for reducing microbiological activity in drain runoff areas having a housing (10), the housing having an inner wall (16) defining an inner opening (18) in the housing, an outer wall (12), and a bottom wall (14) defining a central cavity (15) in the housing (10), a tear strip (20) for destructibly removing the housing outer wall and a portion of the bottom wall (14), a handle (30) spanning the inner opening (18) of the housing (10) and joined to the inner wall (16) of said housing (10); and a chemical sanitizing agent (40).
    Type: Grant
    Filed: September 21, 1988
    Date of Patent: May 28, 1991
    Assignee: Ecolab Inc.
    Inventors: Francis L. Richter, James Wilson, Daniel E. Pedersen
  • Patent number: 5019517
    Abstract: A detector system (10) especially suited for detecting a halogen containing component in a gas stream includes a gas chromatograph (12), which is connected by gas line (13) to pyrolysis chamber (14). Sources (16) of additional gas streams are connected by a gas line (18) to the pyrolysis chamber (14). The detector electrodes in the pyrolysis chamber (14) are electrically connected to detector electronics (20) by line (22). A temperature control circuit (24) is electrically connected to heater (26) by line (28). Heater (26) is thermally coupled to the pyrolysis chamber (b 14) at (30). The pyrolysis chamber (14) is thermally coupled to thermocouple (32) at (34). The thermocouple (32) is electrically connected to the temperature control circuit (24) by line (36). The heater (26) is independent of the detector electrodes and maintains a temperature between about 700 degrees and 1000 degrees Centigrade. The detector electrodes are substantially alkali metal free.
    Type: Grant
    Filed: April 15, 1988
    Date of Patent: May 28, 1991
    Inventor: Dale M. Coulson
  • Patent number: 4988625
    Abstract: A solid support chemistry system which, with a dinitrofluorobenzene based assay, can be used to define titers of ligands and chemistry distal to the support. Cleavable diamine cystamines or 1,6-diamino-3,4-dihydroxyhexane are bonded to the solid support.
    Type: Grant
    Filed: November 9, 1988
    Date of Patent: January 29, 1991
    Assignee: Merck & Co., Inc.
    Inventors: Stephen Marburg, Richard L. Tolman
  • Patent number: 4981648
    Abstract: A process is disclosed for inhibiting corrosion of an iron based metal in contact with the system water in an aqueous system, which comprises incorporating into the system water an effective amount of bis-phosphonic acid ethers selected from the group consisting of compounds having the formula (HO).sub.2 OP--R--(OR').sub.n --OR--PO(OH).sub.2 wherein each R is independently selected from the group consisting of methylene and ethylene, wherein R' is selected from the group consisting of methylene, ethylene and ethylene substituted with one or more methyl groups and wherein n is an integer from 0 to 4, and water soluble salts of said bis-phosphonic acid ethers. Advantageous corrosion inhibition using the bis-phosphonic acid ethers in combination with hydroxymethylphosphonic acid is also disclosed.
    Type: Grant
    Filed: November 9, 1988
    Date of Patent: January 1, 1991
    Assignee: W. R. Grace & Co.-Conn.
    Inventors: Ranjit Kumar, Charles G. Carter
  • Patent number: 4981649
    Abstract: The present invention provides methods and means for lid sterilization and temporal sealing. With the lid sterilization means, a lid's whole surface is completely sterilized, while it is held and revolved, and the lid then is put on the opening of a container which is hung by a flange on a pair of rails and carried by a pushing plate. With the temporal sealing means, the lid is partially pushed on the flange by a heater and is briefly and temporarily sealed.
    Type: Grant
    Filed: March 10, 1989
    Date of Patent: January 1, 1991
    Assignees: Snow Brand Milk Products Co., Ltd., Yoshino Kogyosho Co., Ltd.
    Inventors: Yoshito Shibauchi, Kohichi Hatanaka, Tatsuo Tanaka, Katsuyuki Mogi, Tadashi Hanada