Patents Examined by Thomas A Giuliani
  • Patent number: 10660702
    Abstract: Systems, devices, and methods for electroporation ablation therapy are disclosed, with the device including a set of splines coupled to a catheter for medical ablation therapy. Each spline of the set of splines may include a set of electrodes formed on that spline. The set of splines may be configured for translation to transition between a first configuration and a second configuration. The devices described herein may be used to form a lesion via focal ablation.
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: May 26, 2020
    Assignee: Farapulse, Inc.
    Inventors: Raju Viswanathan, Allan Zingeler, Gary Long, Jean-Luc Pageard, Brittney Hachey
  • Patent number: 10660688
    Abstract: A cryoprotective device includes a hollow cryoprotective probe having a distal tip, a removable obturator, and at least one integral temperature sensor monitoring temperature at least adjacent the distal tip. An injector is able to inject a cryoprotective substance (CPS) through the cryoprotective probe and out the distal tip when the obturator is removed. The CPS is of a material that prevents freezing of a substance at which it is injected when adjacent cryotherapy occurs. A processor monitors temperature of the at least one the temperature sensor and can indicate if a preset limit is exceeded.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: May 26, 2020
    Inventors: Gary Kalser, Gregory L. Mayback
  • Patent number: 10653477
    Abstract: An improved surgical instrument having an end effector mounted on the end of an elongate shaft extending from a handle. The end-effector is capable of several different operations, including grasping, cutting, and sealing and/or coagulating tissue, and one of the operations is controlled by a trigger mechanism contained within the handle. In some embodiments, the end effector includes a blade assembly, the trigger mechanism being formed of a three pivot slider-crank mechanism arranged to drive the blade assembly longitudinally along a rotatable drive shaft contained within the elongate shaft. As such, the mechanism is configured so as to drive the blade assembly with enough force that the cutting blade is able to cut through tissue without the user needing to apply any additional force to the trigger, the me. Such an arrangement is particularly advantageous when the blade is being used to cut thick tissue.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: May 19, 2020
    Assignee: GYRUS MEDICAL LIMITED
    Inventor: Marno Nagtegaal
  • Patent number: 10653874
    Abstract: An apparatus for mechanically manipulating hollow organs within the body of a subject, or an organ manipulation apparatus, includes a manipulation section. The manipulation section may include a substantially two-dimensional element, which may have a width that exceeds a distance across a portion of the interior of a hollow organ within which the manipulation section is to be positioned. The manipulation section is configured to manipulate at least a portion of a hollow organ from within, which may modify at least one of a shape, orientation, or location of at least part of the hollow organ. Methods for manipulating hollow organs are also disclosed, as are operating techniques, such as left atrial ablation, in which the shapes, orientations, and/or locations of hollow organs are manipulated to move the hollow organs away from the site of the medical procedure, reducing the potential for damage to the hollow organs.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: May 19, 2020
    Assignee: CIRCA Scientific, Inc.
    Inventor: Shawn P. Fojtik
  • Patent number: 10646265
    Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: May 12, 2020
    Assignee: Cryotherapeutics GmbH
    Inventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
  • Patent number: 10631915
    Abstract: An RF electrode can have a straight shaft to generate an RF heat lesion that is asymmetric about the central axis of the cannula through which the RF electrode is introduced into bodily tissue. For example, system for tissue ablation including a cannula and an electrode, the cannula including an elongated shaft having a proximal end and a distal end, the cannula shaft including an electrically conductive active tip distal to an electrically insulated cannula shaft portion, the cannula shaft including a lumen extending from a proximal opening at the proximal end of the shaft to a distal portion of the shaft.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: April 28, 2020
    Assignee: COSMAN INSTRUMENTS, LLC
    Inventor: Eric R. Cosman
  • Patent number: 10617465
    Abstract: An improved surgical instrument having an end-effector capable of several different operations, including grasping, cutting, and sealing and/or coagulating tissue, and one of the operations is controlled by handle that is moveable relative to instrument to move end effector between two conditions. Providing a simplified latching mechanism for this moveable handle, which latching mechanism is formed of single integrally formed component arranged to engage with handle to allow end effector to be retained in one condition, thus leaving user's hand free to perform other functions of instrument. Therefore, a user may use surgical instrument to grasp tissue between end effector by activating end effector using handle, then use latch mechanism to latch handle in the end effector activation position, allowing surgeon to remove his hand from handle and perform some other task.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: April 14, 2020
    Assignee: GYRUS MEDICAL LIMITED
    Inventors: Marno Nagtegaal, Lewis Meurig Jones
  • Patent number: 10617467
    Abstract: Systems, devices, and methods for electroporation ablation therapy are disclosed, with the device including a set of splines coupled to a catheter for medical ablation therapy. Each spline of the set of splines may include a set of electrodes formed on that spline. The set of splines may be configured for translation to transition between a first configuration and a second configuration.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: April 14, 2020
    Assignee: Farapulse, Inc.
    Inventors: Raju Viswanathan, Allan Zingeler, Gary Long, Jean-Luc Pageard
  • Patent number: 10610663
    Abstract: A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat at least one of non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: April 7, 2020
    Assignee: Fractyl Laboratories, Inc.
    Inventors: Harith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
  • Patent number: 10603062
    Abstract: Pericardial modification devices and methods can be used for the treatment of heart conditions. For example, this document describes devices and methods for treating heart failure with preserved ejection fraction, including diastolic heart failure, by performing a pericardial modification procedure. In one example embodiment, a method for treating diastolic heart failure includes creating an opening in a patient's pericardial tissue, or removing a portion of the patient's pericardial tissue. The creation of the opening or the removing of the pericardial tissue reduces pressure exerted by the pericardial tissue on the patient's heart. The pericardial modification procedures are performed while avoiding trauma to the epicardial surface of heart as well as the phrenic nerves.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: March 31, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Barry A. Borlaug, Vojtech Melenovsky
  • Patent number: 10602938
    Abstract: Systems and methods for noncontact ablation of tissues or materials in/on the body using a luminal catheter and a catheter inserted into the lumen. In one embodiment, the luminal catheter is an ablation catheter and the other catheter is a recording/measurement/positioning catheter. The luminal catheter incorporates a noncontact ablation element such as an ultrasonic transducer. The luminal catheter can be inserted through the skin and into the body (e.g., into the heart) and the recording/measurement/positioning catheter can be inserted into the lumen so that the ablation and recording/measurement/positioning catheters are simultaneously positioned to record/measure the electrical activity of the target tissue and ablate the target tissue without causing the trauma that results from the introduction of additional catheters. Either of the ablation and recording/measurement/positioning catheters can be steerable, and either may incorporate recording/measurement electrodes.
    Type: Grant
    Filed: February 18, 2019
    Date of Patent: March 31, 2020
    Inventor: Hue-Teh Shih
  • Patent number: 10595931
    Abstract: A liquid feeder mounted on a treatment instrument, includes: a main tube that is arranged along a long member of the treatment instrument in which a longitudinal axis is defined and that is configured to flow a liquid to an outer circumference of the long member; a connection section that is arranged on a proximal end side of the main tube along the longitudinal axis and that is configured to connect an interior of the main tube and an interior of a liquid feed channel from a liquid source; and a fixing section that is arranged in the connection section and that is configured to fix the connection section to a handle unit arranged at a proximal end of the long member and grasped by a user.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: March 24, 2020
    Assignee: OLYMPUS CORPORATION
    Inventors: Mizuki Komiya, Kazunori Taniguchi
  • Patent number: 10588692
    Abstract: A gap between a plurality of ablation sites in a heart that hinders electrical propagation therethrough is found by projecting the locations of the sites in a 3-dimensional coordinate system onto a simulation plane, identifying a set of shortest 3-dimensional paths that correspond to 2-dimensional connections between pairs of the projected locations of the sites, and reporting a gap as a longest one of the set.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: March 17, 2020
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Eitan Moshe Saba, David Izraeli, Meir Bar-Tal, Doron Moshe Ludwin
  • Patent number: 10588686
    Abstract: A surgical instrument configured to facilitate access to interior components thereof for cleaning and refurbishment purposes includes a housing assembly, an elongated shaft assembly and an end effector. The housing assembly includes an actuator, and the elongated shaft assembly includes an interior control member operatively coupled to the actuator. The elongated shaft assembly also includes outer cover including first and second cover members and a hinge coupling the first and second cover members to one another such that the outer cover may be selectively moved between a closed configuration wherein the interior control member is enclosed within the outer cover and an open configuration wherein the interior control member is exposed. The end effector is supported at a distal end of the elongated shaft assembly, and is operatively associated with the interior control member.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: March 17, 2020
    Assignee: Covidien LP
    Inventors: James D. Allen, IV, Robert M. Sharp, Kristel L. Ambrosius, Glenn A. Horner, Daniel A. Joseph, Peter M. Mueller, Duane E. Kerr, Ryan C. Artale
  • Patent number: 10588691
    Abstract: Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: March 17, 2020
    Assignee: Relievant Medsystems, Inc.
    Inventors: Richard Pellegrino, Paula Papineau, John S. Crombie, Samit Patel, Thomas Ryan
  • Patent number: 10576244
    Abstract: A lumen extension member is provided for a catheter having a catheter body and an elongate electrode coupled to the catheter body. The elongate electrode defines an electrode lumen extending therethrough. The lumen extension member is positioned within the electrode lumen and is coupled to the catheter body. The lumen extension member includes a tubular member including a sidewall and at least one opening that extends through the sidewall.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: March 3, 2020
    Assignee: ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.
    Inventors: Alan de la Rama, Cary Hata, William Du, Yongxing Zhang
  • Patent number: 10575865
    Abstract: A forceps includes first and second shaft members each having a jaw member disposed at a distal end thereof. One (or both) of the first and second jaw members is moveable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. The first jaw member includes a jaw frame fixedly engaged to the first shaft member and a disposable jaw housing releasably engageable with the jaw frame. The disposable jaw housing includes a knife assembly disposed therein. The knife assembly includes a knife blade biased toward an initial position, wherein the knife blade is disposed within the jaw housing. The knife blade is moveable between the initial position and an extended position, wherein the knife blade extends at least partially from the jaw housing to cut tissue grasped between the first and second jaw members.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: March 3, 2020
    Assignee: Covidien LP
    Inventors: Grant T. Sims, Chase Collings, Jeffrey R. Townsend
  • Patent number: 10575890
    Abstract: Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: March 3, 2020
    Assignee: Zeltiq Aesthetics, Inc.
    Inventors: Leonard DeBenedictis, George Frangineas, Jr., Kristine Tatsutani, Bryan J. Weber, Kerrie Jiang, Peter Yee, Linda Pham, Gurvinder Singh Nanda
  • Patent number: 10568683
    Abstract: An arrangement where surgical instrument having shaft with end effector mounted thereon is provided with rotation wheel to allow user to rotate shaft during use into desired angular position. To allow compact and reliable mechanism the rotation wheel, outer edge of which is generally accessible at external surface of instrument, has internal space around axis of wheel within which is provided part of actuation mechanism for end effector. To allow rotation of actuation mechanism with end effector, part of actuation mechanism located within wheel rotationally mutually engages with inner surface of internal space within wheel, wherein rotation of wheel by user causes actuation mechanism to rotate, which in turn rotates shaft wherein end effector is mounted. Providing benefits allowing otherwise redundant space within rotation wheel to accommodate part of actuation mechanism for end effector, improving compactness of device, whilst still allowing rotation of end-effector and its corresponding actuation mechanism.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: February 25, 2020
    Assignee: GYRUS MEDICAL LIMITED
    Inventor: Marno Nagtegaal
  • Patent number: 10568678
    Abstract: Methods and apparatuses are provided for neutral drive feedback loop compensation of detected electrosurgical unit signals. An apparatus includes an electrosurgery unit (ESU) signal detection circuit, a compensation switch, and an ESU filter switch. Both switches activate based on an output of the ESU signal detection circuit. A neutral drive feedback loop circuit is configured to compensate for a phase change characteristic of an ESU filter circuit.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: February 25, 2020
    Assignee: DR√ĄGERWERK AG & CO. KGAA
    Inventor: Pericles Nicholas Bakalos