Patents Examined by Timothy J. Kugel
  • Patent number: RE47033
    Abstract: A pharmaceutical composition comprises a solid adsorbate comprising a drug adsorbed onto a substrate and a lipophilic microphase-forming material. The solid adsorbate may also be co-administered with a lipophilic microphase-forming material to an in vivo use environment. The compositions of the present invention enhance the concentration of drug in a use environment.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: September 11, 2018
    Assignee: Bend Research, Inc.
    Inventors: Walter C. Babcock, Dwayne T. Friesen, Ravi M. Shanker, Daniel T. Smithey
  • Patent number: RE47034
    Abstract: Embodiments of topical formulations for administering compound I or a pharmaceutically acceptable salt or solvate thereof are disclosed. Embodiments of methods for using the topical formulations in the treatment of dermatological disorders such as cutaneous collagen vascular diseases, e.g., cutaneous lupus, also are disclosed.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: September 11, 2018
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Thomas Sun, Matt Duan
  • Patent number: RE47084
    Abstract: The field of the invention is that of oral pharmaceutical medicinal products or compositions, more particularly of the type of those comprising one or more active principles. The aim of the invention is to provide an improved oral medicinal product that can be administered in one or more daily doses, with modified release of active principle (in particular an active principle), for improving the prophylactic and therapeutic efficacy of such a medicinal product. This aim is achieved by means of the multimicrocapsular oral pharmaceutical form according to the invention in which the release of the AP is controlled by means of a double mechanism of triggering the release: “time triggering” and “pH triggering”. This medicinal product comprises microcapsules with modified release of active principle, each containing a core comprising the active principle and one or more swelling agents, and at least one coating making possible the modified release of the active principle.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: October 16, 2018
    Assignee: FLAMEL IRELAND LIMITED
    Inventors: Catherine Castan, Florence Guimberteau, Remi Meyrueix, Gerard Soula
  • Patent number: RE47104
    Abstract: The present invention relates to a water-absorbing composition comprising water-absorbing polymer structures, on the surface of which is at least one tannin fraction which has a number-average molecular weight, determined in accordance with the test method described herein, of at least 1,000 g/mol, which has a weight-average molecular weight, determined in accordance with the test method described herein, of at least 1,000 g/mol, or which is a hydrolysable gallotannin. The present invention also relates to a process for the preparation of a water-absorbing composition, the water-absorbing composition obtainable by this process, a composite, a process for the production of a composite, the composite obtainable by this process, chemical products, such as, for example, hygiene articles, the use of a water-absorbing composition or of a composite and the use of a tannin fraction.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: October 30, 2018
    Assignee: Evonik Degussa GmbH
    Inventors: Franck Furno, Laurent Wattebled, Anne Ix-Mund, Harald Schmidt, Markus Henn, Jörg Harren
  • Patent number: RE47214
    Abstract: The present invention relates to polymorphs and solvates of the hydrochloride salt of 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine (P027), processes for their preparation, and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: January 29, 2019
    Assignee: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Ramón Berenguer Maimó, Jorge Medrano Rupérez, Jordi Benet Buchholz, Laura Puig Fernandez, Laia Pellejà Puxeu
  • Patent number: RE47231
    Abstract: The present invention relates to methods and compositions for sealing localized regions of damaged lung tissue to reduce overall lung volume. The glue compositions provide a glue featuring an adhering moiety coupled to one or more other moieties including, for example, a cross-linkable moiety and/or one other adhering moiety. The methods and compositions of the invention find use, for example, in treating pulmonary conditions, such as emphysema.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: February 12, 2019
    Assignee: PneumRx, Inc.
    Inventors: Glen Gong, Ronald Dieck
  • Patent number: RE47319
    Abstract: A water soluble adhesive for use in assembling toy interlocking plastic building blocks is disclosed which add strength to assembled structures yet enables easy disassembly and reuse.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: March 26, 2019
    Assignee: Spill-Tech Laboratory Co.
    Inventors: Leon H. Phillips, III, Leon H. Phillips, Jr., Benny R. Wood
  • Patent number: RE47325
    Abstract: A method for the formation of lithium includes a layer on a substrate using an atomic layer deposition method. The method includes the sequential pulsing of a lithium precursor through a reaction chamber for deposition upon a substrate. Using further oxidizing pulses and or other metal containing precursor pulses, an electrolyte suitable for use in thin film batteries may be manufactured.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: March 26, 2019
    Assignee: Universitetet I Oslo
    Inventors: Ola Nilsen, Helmer Fjellvåg, Mari Endresen Alnes, Titta Aaltonen, Matti Putkonen
  • Patent number: RE47391
    Abstract: A solid state imaging device includes a substrate, in which the substrate includes a photoelectric conversion unit that generates a charge according to a light amount of incident light by a pixel unit, an accumulation unit that divides the charge of the pixel unit which is generated in the photoelectric conversion unit and accumulates the charge, a first element isolation unit that is formed at a boundary of the photoelectric conversion unit of the pixel unit, and a second element isolation unit that is formed at a boundary of the accumulation unit of a divided unit of the pixel.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: May 14, 2019
    Assignee: Sony Semiconductor Solutions Corporation
    Inventor: Hiroaki Seko
  • Patent number: RE47392
    Abstract: A solid state imaging device includes a substrate, in which the substrate includes a photoelectric conversion unit that generates a charge according to a light amount of incident light by a pixel unit, an accumulation unit that divides the charge of the pixel unit which is generated in the photoelectric conversion unit and accumulates the charge, a first element isolation unit that is formed at a boundary of the photoelectric conversion unit of the pixel unit, and a second element isolation unit that is formed at a boundary of the accumulation unit of a divided unit of the pixel.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: May 14, 2019
    Assignee: Sony Semiconductor Solutions Corporation
    Inventor: Hiroaki Seko
  • Patent number: RE47404
    Abstract: The present disclosure relates to methods for treating viral hepatitis, compounds useful in the treatment of viral hepatitis, and pharmaceutical compositions comprising such compounds. In one embodiment, pharmaceutical compositions comprising nitazoxanide, tizoxanide, or derivatives and/or mixtures thereof are provided, as well as methods of treating hepatitis C using such compositions.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: May 28, 2019
    Assignee: ROMARK LABORATORIES, L.C.
    Inventor: Jean-Francois Rossignol
  • Patent number: RE47415
    Abstract: There is disclosed pyridine- and pyrimidinecarboxamide compounds useful as pharmaceutical agents, synthesis processes, and pharmaceutical compositions which include pyridine- and pyrimidinecarboxamides compounds. More specifically, there is disclosed a genus of CXCR2 inhibitor compounds that are useful for treating a variety of inflammatory and neoplastic disorders.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: June 4, 2019
    Assignee: Syntrix Biosystems, Inc.
    Inventors: Dean Y. Maeda, John A. Zebala
  • Patent number: RE47448
    Abstract: Disclosed are thickener compositions composed of xanthan gum and a chelating agent, such as ascorbic acid. The chelating agent is present in an amount with respect to said xanthan such that, when said thickener composition is used to thicken a food product, at least one mineral selected from the group consisting of iron, zinc, and calcium present in said food product is relatively more bioavailable than the mineral would be in the absence of said chelating agent. The thickener composition finds particular applicability for use with baby formulas and breast milk intended for dysphagic infants. Also disclosed are baby formulas and thickened breast milk formulations, methods for preparing same, and methods for providing nutrition.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: June 25, 2019
    Assignee: Kent Precision Foods Group, Inc.
    Inventor: Douglas A. Stetzer
  • Patent number: RE47452
    Abstract: A method for immobilizing dyes and antimicrobial agents on a polymeric cover or housing for a medical device is disclosed and described. The surface may be that of a catheter, a connector, a drug vial spike, a bag spike, a prosthetic device, an endoscope, a surface of an infusion pump, a key pad, a touch screen or a handle. The surfaces may also be one or more of those associated with a infusion of a medicament or dialysis treatment, such as peritoneal dialysis or hemodialysis, where it is important that the working surface for the dialysis fluid be sterile. These surfaces include connectors for peritoneal dialysis sets or for hemodialysis sets, bag spikes, dialysis catheters, and so forth. A method for determining whether a surface has been sterilized, and a dye useful in so indicating, is also disclosed.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: June 25, 2019
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Tuan Bui, Ton That Hai, Mark Nordhaus, Paul Sanders, Cong Jiang, David Lamb, Ozlem Yardimci, Kent L. Lurvey, Vadim V. Krongauz
  • Patent number: RE47512
    Abstract: Disclosed herein is a composition and method of making a polymerizable antibacterial/antimicrobial resin and using such a bioactive resin in formulated dental compositions.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: July 16, 2019
    Assignee: DENTSPLY SIRONA INC.
    Inventor: Xiaoming Jin
  • Patent number: RE47649
    Abstract: A method of cleaning a wellbore prior to the production of oil or gas is disclosed, wherein the wellbore has been drilled with an invert emulsion drilling mud that forms an invert emulsion filter cake. The method may include the steps of circulating a breaker fluid into the wellbore, where the breaker fluid includes an aqueous fluid, and imino diacetic acid or salt thereof. Optionally an acid buffering agent, and a weighting age are also included. The breaker fluid is formulated such that after a predetermined period of time and the filter cake present in the wellbore or on the wellbore face is substantially degraded. Other methods may also include drilling the wellbore with a water-based drilling mud that forms a water-based filter cake, wherein the method may include the steps of circulating a breaker fluid into the wellbore, where the breaker fluid may include an aqueous fluid, and an iminodiacetic acid or a salt thereof.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: October 15, 2019
    Assignee: M-I L.L.C.
    Inventors: Andrew G. K. Jones, Mark Luyster, Raul Navarro-Mascarell
  • Patent number: RE47650
    Abstract: A method for etching a tungsten containing layer in an etch chamber is provided. A substrate is placed with a tungsten containing layer in the etch chamber. A plurality of cycles is provided. Each cycle comprises a passivation phase for forming a passivation layer on sidewalls and bottoms of features in the tungsten containing layer. Additionally, each cycle comprises an etch phase for etching features in the tungsten containing layer.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: October 15, 2019
    Assignee: Lam Research Corporation
    Inventors: Ramkumar Subramanian, Anne Le Gouil, Yoko Yamaguchi
  • Patent number: RE47695
    Abstract: Methods and systems for integral storage and blending of the materials used in oilfield operations are disclosed. A modular integrated material blending and storage system includes a first module comprising a storage unit, a second module comprising a liquid additive storage unit and a pump for maintaining pressure at an outlet of the liquid additive storage unit. The system further includes a third module comprising a pre-gel blender. An output of each of the first module, the second module and the third module is located above a blender and gravity directs the contents of the first module, the second module and the third module to the blender. The system also includes a pump that directs the output of the blender to a desired down hole location. The pump may be powered by natural gas or electricity.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: November 5, 2019
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Leonard R. Case, Ed B. Hagan, Calvin L. Stegemoeller, Ron Hyden
  • Patent number: RE47739
    Abstract: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: November 26, 2019
    Assignee: Warner-Lambert Company LLC
    Inventors: Mark Barvian, Richard John Booth, John Quinn, III, Joseph Thomas Repine, Derek J. Sheehan, Peter Lawrence Toogood, Scott Norman Vanderwel, Hairong Zhou
  • Patent number: RE47741
    Abstract: Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R11 and R12 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: November 26, 2019
    Assignee: Achaogen, Inc.
    Inventors: Paola Dozzo, Adam Aaron Goldblum, James Bradley Aggen, Martin Sheringham Linsell