Abstract: Apurinic/apuyrimidinic endonuclease 1/Redox Factor-1 (APE/Ref-1) inhibitors are provided along with methods of using the same. The inhibitor has the structure of Formula I: or a pharmaceutically acceptable salt thereof. n is an integer from 4 to 14, X and X? are each independently H or OH, and Y and Y? are each independently H or OH.

Abstract: There is provided a method of creating an augmented reality image, comprising: capturing by an imaging sensor of a mobile device, a two dimensional (2D) image of a three dimensional scene (3D) comprising objects and pixel neighborhoods, selecting with a graphical user interface (GUI) presented on a display of the mobile device, pixel(s) of the 2D image corresponding to a certain object, computing a 3D geo-location of the certain object corresponding to the selected pixel(s) of the 2D image, wherein the 3D geo-location includes an altitude relative to sea level, and wherein the 3D geo-location is geographically distinct and spaced apart from a location of the imaging sensor outputted by a location sensor, and creating a tag for the selected pixel(s) of the certain object of the 2D image according to the computed 3D geo-location within a virtual grid, wherein the tag maps to media-object(s) correspond with real world coordinates.

Abstract: There is provided a method of creating an augmented reality image, comprising: capturing by an imaging sensor of a mobile device, a two dimensional (2D) image of a three dimensional scene (3D) comprising objects and pixel neighborhoods, selecting with a graphical user interface (GUI) presented on a display of the mobile device, pixel(s) of the 2D image corresponding to a certain object, computing a 3D geo-location of the certain object corresponding to the selected pixel(s) of the 2D image, wherein the 3D geo-location includes an altitude relative to sea level, and wherein the 3D geo-location is geographically distinct and spaced apart from a location of the imaging sensor outputted by a location sensor, and creating a tag for the selected pixel(s) of the certain object of the 2D image according to the computed 3D geo-location within a virtual grid, wherein the tag maps to media-object(s) correspond with real world coordinates.

Abstract: The present invention relates to a protienaceous compound or functionally active derivative or part thereof having a binding site for a group represented by formula (I) which is part of a group of toxins derived from various cyanobacteria, to a method for its production, to diagnostic kits and to an affinty matrix (e.g. for use in immunoaffinity columns, online detection and purifications devices) containing the proteinaceous compound as well as to methods for substantially decreasing the amount of a compound containing the group represented by formula (I) in fluids or for concentrating compounds, e.g. toxins, containing the group represented by formula (I) from fluids such as crude water samples, extracts of algae or other tissue samples, e.g. to determine toxin concentrations.

Abstract: A method of inhibiting the transport of a neurotransmitter away from the synapse comprising contacting a neurotransmitter transporter with a compound having the structure ##STR1## wherein ##STR2## or CONHR.sup.3 in any combination and and wherein R.sup.2 =OR.sup.3, NR.sup.3.sub.2, alkyl, or substituted alkyl and R.sup.3 =alkyl or substituted alkyl.

Abstract: A method for producing highly detailed and multi-relief nameplates. A master image is produced by photoetching with a photopolymer. A negative production tool is formed from this master image, and comprises a plurality of individual nameplates formed in a sheet. The sheet is plated with a thin layer of nickel, and backfilled with a mixture of nylon and an epoxy resin, which is then cured to produce a solid mass. The obverses of the nameplates are chrome-plated and may be painted as desired. The reverse of the sheet is subjected to a cutting step using a fly cutting mill which separates the sheet by horizontally cutting raised edges between adjoining nameplates to produce a plurality of individual nameplates.