Patents by Inventor Abdul Gaffar

Abdul Gaffar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5401723
    Abstract: Enhancement of the method and oral compositions for inhibiting adherence of Streptococcus pyogenes to pharyngeal and oral mucosa cells by treating these areas with a glycoconjugate comprising an oligosaccharide linked to a carrier. The oligosaccharide should have at least one fucose moiety or a galatose moiety which is free of digalactose and N-acetylneuraminyl lactose. The carrier may include albumins, starch or synthetic polymers.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: March 28, 1995
    Assignees: Colgate-Palmolive Company, Forsyth Dental
    Inventors: Abdul Gaffar, Ronald Gibbons, Stanislawa Tylewska
  • Patent number: 5374417
    Abstract: A dentifrice for desensitizing sensitive teeth wherein a potassium salt of a synthetic anionic polymer is present to close off subsequent penetration of pain to dental pulp.
    Type: Grant
    Filed: October 6, 1993
    Date of Patent: December 20, 1994
    Assignee: Colgate Palmolive Company
    Inventors: James Norfleet, Willie J. Carter, Matthew J. Frankel, Abdul Gaffar
  • Patent number: 5368845
    Abstract: An antiplaque composition comprising a bacteriocin such as nisin and a polyphosphonate.
    Type: Grant
    Filed: January 7, 1993
    Date of Patent: November 29, 1994
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, John Afflitto, Malathy Subramanian
  • Patent number: 5368844
    Abstract: Oral composition containing an effective amount of N-methylpyrrolidone alone or in combination with a noncationic antibacterial agent such as Triclosan for topical application for the prevention of plaque, gingivitis and/or caries.
    Type: Grant
    Filed: August 5, 1993
    Date of Patent: November 29, 1994
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, John J. Afflitto, Malcolm I. Williams
  • Patent number: 5356615
    Abstract: An antiplaque oral composition, such as a toothpaste, gel dentifrice, tooth powder, mouthrinse or mouthwash, tooth hardener, anticalculus composition, gum or lozenge, comprises triclosan as an antiplaque component, the antiplaque action of which is unexpectedly and beneficially increased by the presence in the oral composition of a phenolic flavoring agent, such as eucalpytol, thymol, methyl salicylate, menthol, phenol, halogenated derivatives thereof, and mixtures thereof. Preferred such compositions are toothpastes, gel dentifrices and mouthrinses or mouthwashes. Also within the invention are processes of repeatedly applying such antiplaque oral compositions to the teeth to obtain the antiplaque benefits mentioned.
    Type: Grant
    Filed: January 30, 1991
    Date of Patent: October 18, 1994
    Assignee: Colgate Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 5352439
    Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.
    Type: Grant
    Filed: June 4, 1993
    Date of Patent: October 4, 1994
    Assignee: Colgate Palmolive Company
    Inventors: James Norfleet, Willie J. Carter, Matthew J. Frankel, Abdul Gaffar
  • Patent number: 5344641
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methyl cellosolve and ethyl cellosolve; a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: September 6, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5334375
    Abstract: An oral composition containing a substantially water insoluble noncationic antibacterial antiplaque agent such as triclosan and a synthetic cross-linked polymer such as cross-linked poly (methylvinyl ether/maleic acid or anhydride) as antibacterial-enhancing agent to enhance delivery of said antibacterial agent to, and the retention thereof on, oral surfaces, and a method of promoting oral hygiene therewith.
    Type: Grant
    Filed: July 16, 1992
    Date of Patent: August 2, 1994
    Assignee: Colgate Palmolive Company
    Inventors: Nuran Nabi, Michael Prencipe, Abdul Gaffar
  • Patent number: 5312618
    Abstract: An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2.sup.1 -hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: May 17, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer, Michael Prencipe
  • Patent number: 5296214
    Abstract: An oral composition such as a dentifrice or mouth-wash, comprises an effective antiplaque amount of a substantially water-insoluble noncationic antibacterial agents, such as 2,4,4-trichloro-2'-hydroxy-diphenyl ether (Triclosan) and polyvinyl phosphonate antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to oral surfaces.
    Type: Grant
    Filed: August 4, 1992
    Date of Patent: March 22, 1994
    Assignee: Colgate-Palmolive Co.
    Inventor: Abdul Gaffar
  • Patent number: 5294431
    Abstract: An oral composition mouthwash or liquid dentifrice containing an aqueous vehicle acceptable vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: October 16, 1992
    Date of Patent: March 15, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5292526
    Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: October 23, 1992
    Date of Patent: March 8, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5288480
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: October 21, 1992
    Date of Patent: February 22, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5279813
    Abstract: An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula.
    Type: Grant
    Filed: August 18, 1992
    Date of Patent: January 18, 1994
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Richard S. Robinson, Jeffrey Miller, Chimpiramma Potini, Michael A. Collins, Theresa G. Shackil
  • Patent number: 5275805
    Abstract: An antiplaque oral composition such as a gel, paste or mouthrinse which is comprised of a vehicle having incorporated therein as the antiplaque agent an effective amount of an antibacterial salicylanilide compound and a surfactant mixture of an anionic surfactant, a polyoxyethylene/polyoxypropylene block copolymer and a taurate salt, the pH of the composition being adjusted to a pH of at least 8.0. An antibacterial-enhancing agent such as an anionic polymeric polycarboxylate which enhances the delivery of the salicylanilide compound to and retention on oral tissue surfaces is optionally incorporated in the composition to improve the efficacy of the salicylanilide compound.
    Type: Grant
    Filed: June 11, 1993
    Date of Patent: January 4, 1994
    Inventors: Nuran Nabi, Abdul Gaffar, John Afflitto
  • Patent number: 5260062
    Abstract: A dental composition, such as a paste or gel dentifrice containing triclosan, as an antibacterial agent which acts to decrease plaque on the teeth, and polyphosphate for anti-tartar actions, is packaged in a finger actuatable pump-type plastic dispensing container which is made of or includes a solid polymeric material, such as a polyfluoroethylene, which is compatible with triclosan, so that excessive loss of its anti-plaque activity on storage is avoided, which losses have been noted when various other plastics have been employed as dispensing container component materials. Alternatively, others of such plastic may be employed for dispensing container parts when a stabilizer, such as a terpene, e.g., limonene, is present in the dentifrice.
    Type: Grant
    Filed: July 2, 1990
    Date of Patent: November 9, 1993
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 5240697
    Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.
    Type: Grant
    Filed: October 17, 1991
    Date of Patent: August 31, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: James Norfleet, Willie J. Carter, Matthew J. Frankel, Abdul Gaffar
  • Patent number: 5234688
    Abstract: A dental composition, such as a paste or gel dentifrice containing triclosan, as an antibacterial agent which acts to decrease plaque on the teeth, is packaged in a hand holdable and squeezable dispensing container which is made of or includes a part or parts of a solid polymeric material, such as a polyfluoroethylene or polyvinyl chloride, which is compatible with triclosan, so that excessive loss of its anti-plaque activity on storage is avoided, which losses have been noted when various other plastics have been employed as dispensing container component materials. Alternatively, other more reactive plastics may be employed for such dispensing container parts when a stabilizer, such as terpene, e.g., limonene, is present in the dentifrice.
    Type: Grant
    Filed: July 2, 1990
    Date of Patent: August 10, 1993
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 5208009
    Abstract: An anticalculus oral composition, which is preferably a toothpaste or a mouthrinse, includes an effective anticalculus azacycloalkane-2,2-diphosphonic acid or a salt thereof, preferably azacycloheptane-2,2-diphosphonic acid, and a water-soluble or water swellable polymer having a molecular weight of about 1,000-2,000,000, such as a linear copolymer of maleic anhydride and vinyl methyl ether or a polyvinyl phosphonate. The polymer surprisingly increases the anticalculus effectiveness of the azacycloalkane-2,2-diphosphonic acid or salt thereof in such compositions, even at comparatively low concentrations of both such materials. Also within the invention is a process for applying such compositions to the teeth, and it has been shown by both in vitro and in vivo testing that significant repeatable improvements in anticalculus effects are obtained by such processes, compared to control processes in which either of the active components mentioned is employed alone in the described oral compositions.
    Type: Grant
    Filed: November 25, 1991
    Date of Patent: May 4, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, John J. Afflito, Marilou T. Joziak
  • Patent number: 5192531
    Abstract: An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.
    Type: Grant
    Filed: September 9, 1991
    Date of Patent: March 9, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer, Michael Prencipe