Patents by Inventor Abdul Gaffar

Abdul Gaffar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5192530
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methyl cellosolve and ethyl cellosolve; a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.
    Type: Grant
    Filed: September 6, 1991
    Date of Patent: March 9, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5188821
    Abstract: An oral composition mouthwash or liquid dentifrice containing an aqueous vehicle acceptable vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: August 28, 1989
    Date of Patent: February 23, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5180578
    Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: February 19, 1991
    Date of Patent: January 19, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5178851
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: February 14, 1991
    Date of Patent: January 12, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5167951
    Abstract: An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula.
    Type: Grant
    Filed: April 6, 1990
    Date of Patent: December 1, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Richard S. Robinson, Jeffrey Miller, Chimpiramma Potini, Michael A. Collins, Theresa G. Shackil
  • Patent number: 5158763
    Abstract: An oral composition is provided which comprises an oral vehicle and contains at least one antibacterial antiplaque agent which can stain or discolor dental surfaces. Provided in such oral composition is an effective stain-inhibiting amount of an antistaining additive, such additive being azacycloalkane disphosphonic acid or an orally acceptable salt thereof.
    Type: Grant
    Filed: October 9, 1990
    Date of Patent: October 27, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka
  • Patent number: 5156835
    Abstract: An oral composition such as a dentifrice or mouthwash, containing an aqueous phase of water and as solubilizing agent propylene glycol, dipropylene glycol, methyl cellosolve, ethyl cellosolve, olive oil, castor oil, amyl acetate, ethyl acetate, glyceryl tristearate or benzyl benzoate mixed with at least one of glycerine and sorbitol, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (triclosan) or hexyl resorcinol and a synthetic anionic linear polymeric polycarboxylate having a molecular weight of about 1,000 to about 1,000,000.
    Type: Grant
    Filed: August 9, 1991
    Date of Patent: October 20, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Nuran Nabi, Abdul Gaffar
  • Patent number: 5139769
    Abstract: An oral composition such as a toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, to inhibit enzymatic hydrolysis of said polyphosphate salt in saliva, a combination of a fluoride ion-providing source and a synthetic linear polymeric polycarboxylate.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: August 18, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka
  • Patent number: 5135738
    Abstract: An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container or bottle which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque acitivity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. Also described is a method for inhibiting development of plaque on teeth.
    Type: Grant
    Filed: October 26, 1989
    Date of Patent: August 4, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Richard S. Robinson, Jeffrey Miller, Chimpiramma Potini, Michael A. Collins, Theresa G. Shackil
  • Patent number: 5096699
    Abstract: An anticalculus oral composition, which is preferably a toothpaste or a mouthrinse, includes an effective anticalculus azacycloalkane-2,2-diphosphonic acid or a salt thereof, preferably azacycloheptane-2,2-diphosphonic acid, and a polymeric polycarboxylate, which is preferably a linear copolymer of maleic anhydride and vinyl methyl ether of a molecular weight in the range of about 5,000-2,000,000, preferably about 30,000-1,500,000. The copolymer surprisingly increases the anticalculus effectiveness of the azacycloalkane-2,2-diphosphonic acid or salt thereof in such compositions, even at comparatively low concentrations of both such materials.
    Type: Grant
    Filed: December 20, 1990
    Date of Patent: March 17, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, John J. Afflitto, Marilou T. Joziak
  • Patent number: 5094844
    Abstract: An oral composition such as a toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, as inhibitor of enzymatic hydrolysis of said polyphosphate salt in saliva, a synthetic polymeric vinyl phosphate. A fluoride-ion providing source may also be present to further inhibit the enzymatic hydrolysis of said polyphosphate salt.
    Type: Grant
    Filed: December 20, 1990
    Date of Patent: March 10, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, John Afflitto, Sahar F. Smith
  • Patent number: 5095106
    Abstract: A method of, and oral composition for, inhibiting adherence of Streptococcus pyogenes to pharyngeal and oral mucosa cells by treating these cells with an oligosaccharide having at least one fucose moiety or a galactose moiety which is free of digalactose and N-acetylneuraminyl lactose.
    Type: Grant
    Filed: January 11, 1991
    Date of Patent: March 10, 1992
    Assignees: Colgate-Palmolive, Forsyth Dental Center
    Inventors: Abdul Gaffar, Ronald J. Gibbons, Stanislawa Tylewska
  • Patent number: 5089255
    Abstract: A method is disclosed for remineralizing demineralized portions of teeth by treatment with a non-astringent composition containing about 10-20% xylitol, and at least one fluoride ion-providing compound in a total amount sufficient to provide about 150 ppm to about 1800 ppm of fluoride ions, with sodium fluoride providing a predominant proportion of such fluoride ions.
    Type: Grant
    Filed: January 25, 1991
    Date of Patent: February 18, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, James Mellberg, John Blake-Haskins
  • Patent number: 5080887
    Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncatationic antibacterial agent such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (Triclosan).
    Type: Grant
    Filed: August 8, 1991
    Date of Patent: January 14, 1992
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, Brian S. Jannone
  • Patent number: 5043154
    Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (Triclosan).
    Type: Grant
    Filed: May 1, 1989
    Date of Patent: August 27, 1991
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, Brian S. Jannone
  • Patent number: 5037635
    Abstract: An oral composition such as a dentifrice or mouthwash, containing an aqueous phase of water and as solubilizing agent propylene glycol, dipropylene glycol, methyl cellosolve, ethyl cellosolve, olive oil, castor oil, amyl acetate, ethyl acetate, glyceryl tristrearate or benzyl benzoate mixed with at least one glycerine and sorbitol, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (triclosan), and a synthetic anionic linear polymeric polycarboxylate having a molecular weight of about 1,000 to about 1,000,000.
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: August 6, 1991
    Assignee: Colate-Palmolive Company
    Inventors: Nuran Nabi, Abdul Gaffar
  • Patent number: 5034383
    Abstract: Bacterial endotoxins are inhibited by a non-toxic, water-soluble, pharmaceutically acceptable peroxydiphosphate compound in contact with bacterial endotoxin.
    Type: Grant
    Filed: March 13, 1989
    Date of Patent: July 23, 1991
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Edward J. Coleman
  • Patent number: 5032386
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: August 25, 1989
    Date of Patent: July 16, 1991
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5028439
    Abstract: Parathyroid Hormone, when excessively synthesized, induces pathologic bone resorption and demineralization and results in hypocalcemia which produces toxic effects in soft tissues. Non-toxic water-soluble pharmaceutically acceptable compound derivative of peroxydiphosphoric acid, administered orally or systemically, inhibits parathyroid hormone induced bone resorption in vitro and in vivo in warm blooded animals.
    Type: Grant
    Filed: January 9, 1989
    Date of Patent: July 2, 1991
    Assignee: Colgate Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 5017362
    Abstract: An oral composition such as a toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, to inhibit enzymatic hydrolysis of said polyphosphate salt in saliva, a combination of a fluoride ion-providing source and a synthetic linear polymeric polycarboxylate.
    Type: Grant
    Filed: December 8, 1989
    Date of Patent: May 21, 1991
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka