Patents by Inventor Abdullah Mohammed Al Majid

Abdullah Mohammed Al Majid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoformulation of spriooxindole and methods for treating hepatocellular carcinoma
    Patent number: 11944604
    Abstract: A spirooxindole nanoformulation includes a proniosome loaded with a spirooxindole derivative.
    Type: Grant
    Filed: March 10, 2023
    Date of Patent: April 2, 2024
    Assignee: KING SAUD UNIVERSITY
    Inventors: Assem Barakat, Fardous F. El-Senduny, Mohammad Shahidul Islam, Abdullah Mohammed Al Majid, Yaseen Ali Mosa Mohamed Elshaier, Eman Ahmed Ibrahim Mazyed, Farid A. Badria
  • Substituted spirooxindoles
    Patent number: 9822128
    Abstract: The substituted spirooxindoles are MDM2-p53 inhibitors bearing a benzylidine (styryl) arm and have a complex fused ring system ideally suited for binding to the MDM2 protein, thereby interrupting its protein-protein interaction (PPI). Sixteen compounds, designated 4a-4p, were synthesized in a simple smooth method using an asymmetric 1,3-dipolar reaction as the key step. Testing showed that the compounds exhibit anti-cancer activity against various forms of cancer cells affecting humans.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: November 21, 2017
    Inventors: Assem Barakat, Mohammad Shahidul Islam, Abdullah Mohammed Al Majid, Hussain Mansur Ghawas, Fardous F. El-Senduny, Farid A. Badria, Yaseen Ali Mosa Mohamed Elshaier, Hazem A. Ghabbour
  • ?-glucosidase inhibitors
    Patent number: 9802894
    Abstract: Novel ?-Glucosidase inhibitors include propanone substituted indole ring-containing heterocyclic compounds, which are represented by Formula I: Wherein R1 is thiophene, 2,4-di chloro phenyl, 2,6-di chloro phenyl, bromo phenyl, benzyl or nitrophenyl; and R2 is an aryl group, or stereoisomers or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: October 31, 2017
    Assignee: KING SAUD UNIVERSITY
    Inventors: Abdullah Mohammed Al-Majid, Mohammad Shahidul Islam, Assem Barakat, Muhammad Iqbal Choudhary, Sammer Yousuf
  • ALPHA-GLUCOSIDASE INHIBITORS
    Publication number: 20170088516
    Abstract: Novel ?-Glucosidase inhibitors include propanone substituted indole ring-containing heterocyclic compounds, which are represented by Formula I: Wherein R1 is thiophene, 2,4-di chloro phenyl, 2,6-di chloro phenyl, bromo phenyl, benzyl or nitrophenyl; and R2 is an aryl group, or stereoisomers or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: September 29, 2015
    Publication date: March 30, 2017
    Inventors: ABDULLAH MOHAMMED AL-MAJID, MOHAMMAD SHAHIDUL ISLAM, ASSEM BARAKAT, MUHAMMAD IQBAL CHOUDHARY, SAMMER YOUSUF
  • Diethylammonium salts of phenyl-substituted thiobarbituric acid as anti-diabetic agents
    Patent number: 9527820
    Abstract: The diethylammonium salts of phenyl-substituted thiobarbituric acid as anti-diabetic agents include compounds having the formula: wherein X is: and wherein R1 is selected from the group consisting of a hydrogen, halogen, methyl, trifluoromethyl, methoxy, and nitro, and R2 is either halogen or hydrogen, the R1 and R2 substituents being independently bonded to an ortho-, meta-, or para-carbon of the phenyl substituent.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: December 27, 2016
    Assignee: KING SAUD UNIVERSITY
    Inventors: Assem Barakat, Mohamed Ali, Abdullah Mohammed Al Majid, Sammer Yousuf, Muhammad Iqbal Choudhary