Patents by Inventor Abigail L. Reens

Abigail L. Reens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecule inhibitors of bacterial efflux pumps and methods of using same
    Patent number: 11534429
    Abstract: An empirical Screen for Anti-infectives using Fluorescence microscopy of IntracellulaR Enterobacteriaceae (SAFIRE) was developed. Using this methodology, a library of small molecules and identified antimicrobials that are cell permeable and non-host-toxic were screened. Inhibitors of bacterial efflux pumps were identified as being implicated in antibiotic resistance and are attractive therapeutic targets for antimicrobials.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: December 27, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO
    Inventors: Abigail L. Reens, Amy L. Crooks, Corrella S. Detweiler
  • SMALL MOLECULE INHIBITORS OF BACTERIAL EFFLUX PUMPS AND METHODS OF USING SAME
    Publication number: 20220175736
    Abstract: An empirical Screen for Anti-infectives using Fluorescence microscopy of IntracellulaR Enterobacteriaceae (SAFIRE) was developed. Using this methodology, a library of small molecules and identified antimicrobials that are cell permeable and non-host-toxic were screened. Inhibitors of bacterial efflux pumps were identified as being implicated in antibiotic resistance and are attractive therapeutic targets for antimicrobials.
    Type: Application
    Filed: July 30, 2021
    Publication date: June 9, 2022
    Inventors: Abigail L. Reens, Amy L. Crooks, Corrella S. Detweiler
  • Small molecule inhibitors of bacterial efflux pumps and methods of using same
    Patent number: 11110080
    Abstract: An empirical Screen for Anti-infectives using Fluorescence microscopy of IntracellulaR Enterobacteriaceae (SAFIRE) was developed. Using this methodology, a library of small molecules and identified antimicrobials that are cell permeable and non-host-toxic were screened. Inhibitors of bacterial efflux pumps were identified as being implicated in antibiotic resistance and are attractive therapeutic targets for antimicrobials.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: September 7, 2021
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Abigail L. Reens, Amy L. Crooks, Corrella S. Detweiler
  • SMALL MOLECULE INHIBITORS OF BACTERIAL EFFLUX PUMPS AND METHODS OF USING SAME
    Publication number: 20200022961
    Abstract: An empirical Screen for Anti-infectives using Fluorescence microscopy of IntracellulaR Enterobacteriaceae (SAFIRE) was developed. Using this methodology, a library of small molecules and identified antimicrobials that are cell permeable and non-host-toxic were screened. Inhibitors of bacterial efflux pumps were identified as being implicated in antibiotic resistance and are attractive therapeutic targets for antimicrobials.
    Type: Application
    Filed: March 27, 2018
    Publication date: January 23, 2020
    Inventors: Abigail L. Reens, Amy L. Crooks, Corrella S. Detweiler