Patents by Inventor Abram M. Vaccaro

Abram M. Vaccaro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multiplex Amplification Detection Assay II
    Publication number: 20220119862
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: November 5, 2021
    Publication date: April 21, 2022
    Inventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
  • DETECTION OF COLON NEOPLASIA BY ANALYSIS OF METHYLATED DNA
    Publication number: 20220056526
    Abstract: Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
    Type: Application
    Filed: August 23, 2021
    Publication date: February 24, 2022
    Inventors: Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
  • Multiplex amplification detection assay II
    Patent number: 11193168
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: December 7, 2021
    Assignee: Exact Sciences Development Company, LLC
    Inventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
  • Detection of colon neoplasia by analysis of methylated DNA
    Patent number: 11118228
    Abstract: Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: September 14, 2021
    Assignees: Exact Sciences Development Company, LLC, Mayo Foundation for Medical Education and Research
    Inventors: Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
  • MULTIPLEX AMPLIFICATION DETECTION ASSAY II
    Publication number: 20200248233
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: February 12, 2020
    Publication date: August 6, 2020
    Inventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
  • Multiplex amplification detection assay II
    Patent number: 10648025
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: May 12, 2020
    Assignee: EXACT SCIENCES DEVELOPMENT COMPANY, LLC
    Inventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
  • MULTIPLEX AMPLIFICATION DETECTION ASSAY II
    Publication number: 20190177769
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: December 13, 2017
    Publication date: June 13, 2019
    Inventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
  • DETECTION OF COLON NEOPLASIA BY ANALYSIS OF METHYLATED DNA
    Publication number: 20180245157
    Abstract: Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
    Type: Application
    Filed: January 26, 2018
    Publication date: August 30, 2018
    Inventors: Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
  • NON-RADIOACTIVE PHOSPHOLIPID COMPOUNDS, COMPOSITIONS, AND METHODS OF USE
    Publication number: 20120156133
    Abstract: The present invention provides phospholipid ether and alkyl phospholipid compounds and their combinations with other cancer therapy agents. More specifically, the invention relates to the use of phospholipid ether compounds comprising a “cold” isotope of iodine, e.g. 127I, or H, for treating cancer and combinations of phospholipid compounds comprising radioactive (i.e., “hot”) and non-radioactive (i.e., “cold”) isotopes of iodine.
    Type: Application
    Filed: February 23, 2012
    Publication date: June 21, 2012
    Applicant: Cellectar, Inc.
    Inventors: Anatoly Pinchuk, Marc Longino, Jamey P. Weichert, William R. Clarke, Abram M. Vaccaro, Irawati Kandela
  • NON-RADIOACTIVE PHOSPHOLIPID COMPOUNDS, COMPOSITIONS, AND METHODS OF USE
    Publication number: 20110064661
    Abstract: The present invention provides phospholipid ether and alkyl phospholipid compounds and their combinations with other cancer therapy agents. More specifically, the invention relates to the use of phospholipid ether compounds comprising a “cold” isotope of iodine, e.g. 127I, or H, for treating cancer and combinations of phospholipid compounds comprising radioactive (i.e., “hot”) and non-radioactive (i.e., “cold”) isotopes of iodine.
    Type: Application
    Filed: September 10, 2010
    Publication date: March 17, 2011
    Inventors: Anatoly Pinchuk, Marc Longino, Jamey P. Weichert, William R. Clarke, Abram M. Vaccaro, Irawati Kandela