Patents by Inventor Achim Frauenschuh

Achim Frauenschuh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY
    Publication number: 20190233469
    Abstract: The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, and a nonbuffering salt, preferably at high pH, greater than 8.0, is effective in removing impurities, such as high molecular weight species and host cell proteins, while also increasing product concentration in the eluate and maintaining a high percent yield of recovered product.
    Type: Application
    Filed: March 25, 2019
    Publication date: August 1, 2019
    Inventors: Achim Frauenschuh, Bill Kurt
  • Purification method for proteins, in particular antibodies, utilizing a wash solution comprising arginine at high pH for the affinity chromatography step
    Patent number: 9663552
    Abstract: The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, at pH greater than 8.0, is effective in removing impurities without the presence of a nonbuffering salt, while simultaneously increasing product concentration in the eluate and maintaining a high percent yield of recovered product.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: May 30, 2017
    Assignee: Novartis AG
    Inventor: Achim Frauenschuh
  • Wash solution comprising arginine for the affinity chromatography step in antibody purification
    Publication number: 20170044211
    Abstract: The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, and a nonbuffering salt, preferably at high pH, greater than 8.0, is effective in removing impurities, such as high molecular weight species and host cell proteins, while also increasing product concentration in the eluate and maintaining a high percent yield of recovered product.
    Type: Application
    Filed: October 28, 2016
    Publication date: February 16, 2017
    Inventors: Achim Frauenschuh, Kurt Bill
  • Wash solution and method for affinity chromatography
    Patent number: 9505803
    Abstract: The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, and a nonbuffering salt, preferably at high pH, greater than 8.0, is effective in removing impurities, such as high molecular weight species and host cell proteins, while also increasing product concentration in the eluate and maintaining a high percent yield of recovered product.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: November 29, 2016
    Assignee: Novartis AG
    Inventors: Achim Frauenschuh, Kurt Bill
  • Purification method for proteins, in particular antibodies, utilizing a wash solution comprising arginine at high pH for the affinity chromatography step
    Publication number: 20140094593
    Abstract: The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, at pH greater than 8.0, is effective in removing impurities without the presence of a nonbuffering salt, while simultaneously increasing product concentration in the eluate and maintaining a high percent yield of recovered product.
    Type: Application
    Filed: May 31, 2012
    Publication date: April 3, 2014
    Applicant: Novartis AG
    Inventor: Achim Frauenschuh
  • WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY
    Publication number: 20120283416
    Abstract: The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, and a nonbuffering salt, preferably at high pH, greater than 8.0, is effective in removing impurities, such as high molecular weight species and host cell proteins, while also increasing product concentration in the eluate and maintaining a high percent yield of recovered product.
    Type: Application
    Filed: December 17, 2010
    Publication date: November 8, 2012
    Applicant: NOVARTIS AG
    Inventors: Achim Frauenschuh, Kurt Bill
  • CC-chemokine binding tick proteins
    Patent number: 7635576
    Abstract: A novel CC-chemokine binding protein is isolated from the saliva of Rhipicephalus sanguineus. Compounds prepared in accordance with the present invention can be used as anti-inflammatory compounds and in the treatment or prevention of CC-chemokine-related diseases.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: December 22, 2009
    Assignee: Merck Serono SA
    Inventors: Amanda Proudfoot, Christine Power, Achim Frauenschuh
  • NOVEL CC-CHEMOKINE ANTAGONISTS
    Publication number: 20090068173
    Abstract: A novel CC-chemokine binding protein is isolated from the saliva of Rhipicephalus sanguineus. Compounds prepared in accordance with the present invention can be used as anti-inflammatory compounds and in the treatment or prevention of CC-chemokine-related diseases.
    Type: Application
    Filed: December 19, 2005
    Publication date: March 12, 2009
    Applicant: Laboratoires Serono S.A.
    Inventors: Amanda Proudfoot, Christine Power, Achim Frauenschuh
  • CC-chemokine binding tick proteins
    Patent number: 7393660
    Abstract: A novel CC-chemokine binding protein is isolated from the saliva of Rhipicephalus sanguineus. Compounds prepared in accordance with the present invention can be used as anti-inflammatory compounds and in the treatment or prevention of CC-chemokine-related diseases.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: July 1, 2008
    Assignee: Laboratoires Serono SA
    Inventors: Christine Power, Amanda Proudfoot, Achim Frauenschuh
  • Cc-Chemokine Binding Tick Proteins
    Publication number: 20070224125
    Abstract: A novel CC-chemokine binding protein is isolated from the saliva of Rhipicephalus sanguineus. Compounds prepared in accordance with the present invention can be used as anti-inflammatory compounds and in the treatment or prevention of CC-chemokine-related diseases.
    Type: Application
    Filed: December 21, 2004
    Publication date: September 27, 2007
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventors: Christine Power, Amanda Proudfoot, Achim Frauenschuh
  • Novel chemokine-like polypeptides
    Publication number: 20060080744
    Abstract: The present invention discloses open reading frames (ORFs) in human genome encoding for novel chemokines-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
    Type: Application
    Filed: September 29, 2003
    Publication date: April 13, 2006
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventors: Mark Ibberson, Christine Power, Achim Frauenschuh