Patents by Inventor Achim Kless

Achim Kless has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides as KCNQ2/3 modulators
    Patent number: 8653102
    Abstract: The invention relates to substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: February 18, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder
  • Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators
    Patent number: 8618129
    Abstract: The invention relates to substituted 1-oxo-dihydroisoquinoline-3-carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: December 31, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder
  • Substituted sulfonamide compounds
    Patent number: 8580965
    Abstract: Substituted sulfonamide compounds with bradykinin receptor (B1R) modulating activity; processes for the preparation thereof, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat or inhibit pain and/or other disorders and/or disease states.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: November 12, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • Substituted 6-amino-nicotinamides as KCNQ2/3 modulators
    Patent number: 8552200
    Abstract: Substituted 6-amino-nicotinamides, pharmaceutical compositions containing these compounds and also use of these compounds in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: October 8, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder, Simon Lucas
  • Substituted 2-amino-quinoline-3-carboxamides as KCNQ2/3 modulators
    Patent number: 8470852
    Abstract: The invention relates to substituted 2-amino-quinoline-3-carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: June 25, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Dagmar Kaulartz, Achim Kless, Wolfgang Schröder
  • Substituted quinoline-3-carboxamides as KCNQ2/3 modulators
    Patent number: 8445512
    Abstract: The invention relates to substituted quinoline-3—Carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: May 21, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder
  • Substituted sulfonamide compounds
    Patent number: 8435978
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: May 7, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Franz-Martin Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • Substituted 2-mercaptoquinoline-3-carboxamides as KCNQ2/3 modulators
    Patent number: 8399673
    Abstract: The invention relates to substituted 2-mercaptoquinoline-3-carboxamides, methods for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: March 19, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder
  • Substituted tetrahydroimidazopyridine compounds and the use thereof in the treatment of pain and other conditions
    Patent number: 8288424
    Abstract: Substituted tetrahydroimidazopyridine compounds corresponding to formula I: in which R1, R2 and R3 have defined meanings, processes for preparing such compounds, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain, epilepsy, migraine, anxiety or urinary incontinence.
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: October 16, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Stefan Oberboersch, Sven Kuehnert, Gregor Bahrenberg, Achim Kless
  • SUBSTITUTED 6-AMINO-NICOTINAMIDES AS KCNQ2/3 MODULATORS
    Publication number: 20120258947
    Abstract: Substituted 6-amino-nicotinamides, pharmaceutical compositions containing these compounds and also use of these compounds in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: April 18, 2012
    Publication date: October 11, 2012
    Applicant: Grunenthal GmbH
    Inventors: Sven KÜHNERT, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder, Simon Lucas
  • Substituted 2-mercaptoquinoline-3-carboxamides as KCNQ2/3 modulators
    Publication number: 20120252841
    Abstract: The invention relates to substituted 2-mercaptoquinoline-3-carboxamides, methods for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Application
    Filed: June 15, 2012
    Publication date: October 4, 2012
    Applicant: DRUNENTHAL GMBH
    Inventors: Sven KÜHNERT, Gregor BAHRENBERG, Achim KLESS, Wolfgang SCHRÖDER
  • Substituted 2-amino-quinoline-3-carboxamides as KCNQ2/3 modulators
    Publication number: 20120220627
    Abstract: The invention relates to substituted 2-amino-quinoline-3-carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: August 26, 2011
    Publication date: August 30, 2012
    Applicant: Grunenthal GmbH
    Inventors: Sven KÜHNERT, Gregor BAHRENBERG, Dagmar KAULARTZ, Achim KLESS, Wolfgang SCHRÖDER
  • Substituted N-(2-mercaptopyridin-3-yl)amides as KCNQ2/3 modulators
    Patent number: 8247573
    Abstract: The invention relates to substituted N-(2-mercaptopyridin-3-yl)amides, methods for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: August 21, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kühnert, Beatrix Merla, Achim Kless, Gregor Bahrenberg, Wolfgang Schröder
  • SUBSTITUTED 6-AMINO-NICOTINAMIDES AS KCNQ2/3 MODULATORS
    Publication number: 20120101079
    Abstract: Substituted 6-amino-nicotinamides, pharmaceutical compositions containing these compounds and also use of these compounds in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: October 19, 2011
    Publication date: April 26, 2012
    Applicant: Grunenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder, Simon Lucas
  • Substituted 2-oxy-quinoline-3-carboxamides as KCNQ2/3 modulators
    Publication number: 20120053205
    Abstract: The invention relates to substituted 2-oxy-quinoline-3-carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: August 26, 2011
    Publication date: March 1, 2012
    Applicant: Grünenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder
  • Substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides as KCNQ2/3 modulators
    Publication number: 20120053206
    Abstract: The invention relates to substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: August 26, 2011
    Publication date: March 1, 2012
    Applicant: Grunenthal GmbH
    Inventors: Sven KÜHNERT, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder
  • Substituted quinoline-3-carboxamides as KCNQ2/3 modulators
    Publication number: 20120053204
    Abstract: The invention relates to substituted quinoline-3-carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: August 26, 2011
    Publication date: March 1, 2012
    Applicant: Grunenthal GmbH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder
  • Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators
    Publication number: 20120053203
    Abstract: The invention relates to substituted 1-oxo-dihydroisoquinoline-3-carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: August 31, 2011
    Publication date: March 1, 2012
    Applicant: Grunenthal GmbH
    Inventors: Sven KÜHNERT, Gregor BAHRENBERG, Achim KLESS, Wolfgang SCHRÖDER
  • Substituted cyclohexylmethyl compounds
    Patent number: 8058475
    Abstract: Novel cyclohexylmethyl compounds corresponding to formula I wherein R1, R2, R3, R4 and R5, have the meanings given in the description. Pharmaceutical formulations containing these compounds, as well as a processes for preparing these compounds and related methods of treatment are also provided.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: November 15, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Beatrix Merla, Bernd Sundermann, Werner Englberger, Hagen-Heinrich Hennies, Achim Kless, Petra Bloms-Funke, Babette-Yvonne Koegel, Heinze Graubaum
  • Substituted Sulfonamide Compounds
    Publication number: 20100324009
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Application
    Filed: August 24, 2010
    Publication date: December 23, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan OBERBOERSCH, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Franz-Martin Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld