Abstract: Intraluminal devices and methods for removing an obstruction from a blood vessel using an intraluminal device are provided. The intraluminal device can include a flexible shaft and an expandable wire mesh structure extending from the flexible shaft, the wire mesh structure including at least one first expandable section having a first wire arrangement pattern and at least one second expandable section having a second wire arrangement pattern different from the first wire arrangement pattern. In addition, interstices in the at least one second expandable section.

Abstract: In one exemplary embodiment, an intraluminal device may include elongated structure formed of a plurality of wires. The intraluminal device may also include a plurality of sets of looped wires longitudinally located at an intermediate area of the elongated structure and the plurality of sets may be spaced circumferentially about the structure and being configured to cooperate with each other to form a plurality of clot entry openings. At least one grouping of woven wires may be longitudinally located adjacent the intermediate area and the at one grouping of woven wires may be configured such that when an opening force is exerted on the elongated structure, the at least one grouping provides structural support to hold open first interstices between the plurality of sets of looped wires.

Abstract: In one exemplary embodiment, an intraluminal device may include elongated structure formed of a plurality of wires. The intraluminal device may also include a plurality of sets of looped wires longitudinally located at an intermediate area of the elongated structure and the plurality of sets may be spaced circumferentially about the structure and being configured to cooperate with each other to form a plurality of clot entry openings. At least one grouping of woven wires may be longitudinally located adjacent the intermediate area and the at one grouping of woven wires may be configured such that when an opening force is exerted on the elongated structure, the at least one grouping provides structural support to hold open first interstices between the plurality of sets of looped wires.

Abstract: An intraluminal guide wire may include an elongated shaft extending between a distal and a proximal end. The guide wire may include a user actuation segment positioned proximal to the proximal end of the shaft and configured for movement relative to the shaft. The guide wire may include a core wire affixed to the user actuation segment and the distal end of the shaft. The guide wire may also include an inner member having a proximal end situated at least partially within and fixed relative to the user actuation segment and a distal end situated partially within the shaft, the core wire passing through the inner member. The guide wire may be configured with a distal segment of the inner member within the shaft exhibiting a friction-based restraint on movement within the shaft. The friction-based restraint on movement may be a frictional force between the inner member and the shaft.

Abstract: An intraluminal guide wire may include an elongated shaft extending between a distal and a proximal end. The guide wire may include a user actuation segment positioned proximal to the proximal end of the shaft and configured for movement relative to the shaft. The guide wire may include a core wire affixed to the user actuation segment and the distal end of the shaft. The guide wire may also include an inner member having a proximal end situated at least partially within and fixed relative to the user actuation segment and a distal end situated partially within the shaft, the core wire passing through the inner member. The guide wire may be configured with a distal segment of the inner member within the shaft exhibiting a friction-based restraint on movement within the shaft. The friction-based restraint on movement may be a frictional force between the inner member and the shaft.

Abstract: In one exemplary embodiment, an endovascular device may include a hollow shaft having a proximal end and a distal end, and sized for insertion into a blood vessel. The endovascular device may also include a control line having a proximal end and a distal end, and extending through the hollow shaft. The endovascular device may also include an actuatable working element located proximate the distal end of the hollow shaft, and configured to receive an actuation force transmitted via the distal end of the control line. The endovascular device may further include an actuator configured to exert the actuation force on the proximal end of the control line, to thereby cause relative movement between the control line and the hollow shaft and to actuate the working element. The hollow shaft may also include a cable formed of a plurality of wound wires and including a proximal segment, at least one transition segment, and a distal segment.

Abstract: Endovascular and intravascular devices and methods of manufacturing endovascular and intravascular devices may be provided. In one implementation, an intravascular device including an elongated sheath and an elongated coil distal to the sheath may be provided. The coil may include a first coil segment formed from a plurality of wires helically-wound at a first coil angle; a second coil segment formed from a first subset of the plurality of wires that is helically-wound at a second coil angle that is different from the first coil angle; and a third coil segment formed from a second subset of the plurality of wires that is helically-wound at a third coil angle that is different from the first and second coil angles. The coil segments may be configured such that flexibility of the coil increases in a longitudinal direction toward the distal end of the coil.

Abstract: Endovascular and intravascular devices and methods of manufacturing endovascular and intravascular devices may be provided. In one implementation, an intravascular device including an elongated sheath and an elongated coil distal to the sheath may be provided. The coil may include a first coil segment formed from a plurality of wires helically-wound at a first coil angle; a second coil segment formed from a first subset of the plurality of wires that is helically-wound at a second coil angle that is different from the first coil angle; and a third coil segment formed from a second subset of the plurality of wires that is helically-wound at a third coil angle that is different from the first and second coil angles. The coil segments may be configured such that flexibility of the coil increases in a longitudinal direction toward the distal end of the coil.

Abstract: Intraluminal devices and methods for removing an obstruction from a blood vessel using an intraluminal device are provided. The intraluminal device can include a flexible shaft and an expandable wire mesh structure extending from the flexible shaft, the wire mesh structure including at least one first expandable section having a first wire arrangement pattern and at least one second expandable section having a second wire arrangement pattern different from the first wire arrangement pattern. In addition, interstices in the at least one second expandable section.

Abstract: An intraluminal device and a method of removing a clot from a body lumen with an intraluminal device may be provided. The intraluminal device may include a hollow elongated shaft and a radially-expandable mesh segment situated distal to the elongated shaft. The elongated shaft may be secured relative to a first portion of the mesh segment. The intraluminal device may additionally include a core wire affixed to a second portion of the mesh segment and extending through the elongated shaft. The elongated shaft may be configured to radially expand the mesh segment by axially moving the first portion of the mesh segment relative to the second portion of the mesh segment. In addition, the core wire may be configured to radially expand the mesh segment by axially moving the second portion of the mesh segment relative to the first portion of the mesh segment.

Abstract: Intraluminal and endovascular devices and methods of manufacturing intraluminal and endovascular devices may be provided. In one implementation, an intraluminal device may include a sheath having a flexible distal bending segment and a core wire arranged within the sheath. The core wire may include a distal end portion doubled back in a loop within the sheath such that the distal tip of the core wire is situated proximally from the loop. The intraluminal device may also include a movement restrictor within the sheath that is configured to limit axial movement of the distal tip of the core wire. Limiting the axial movement of the core wire distal tip may cause the loop of the core wire to buckle, resulting in a bend in the distal bending segment of the sheath, when a force is exerted on the core wire.

Abstract: In one exemplary embodiment, an endovascular device may include a hollow shaft having a proximal end and a distal end, and sized for insertion into a blood vessel. The endovascular device may also include a control line having a proximal end and a distal end, and extending through the hollow shaft. The endovascular device may also include an actuatable working element located proximate the distal end of the hollow shaft, and configured to receive an actuation force transmitted via the distal end of the control line. The endovascular device may further include an actuator configured to exert the actuation force on the proximal end of the control line, to thereby cause relative movement between the control line and the hollow shaft and to actuate the working element. The hollow shaft may also include a cable formed of a plurality of wound wires and including a proximal segment, at least one transition segment, and a distal segment.

Abstract: An intraluminal device and a method of removing a clot from a body lumen with an intraluminal device may be provided. The intraluminal device may include a hollow elongated shaft and a radially-expandable mesh segment situated distal to the elongated shaft. The elongated shaft may be secured relative to a first portion of the mesh segment. The intraluminal device may additionally include a core wire affixed to a second portion of the mesh segment and extending through the elongated shaft. The elongated shaft may be configured to radially expand the mesh segment by axially moving the first portion of the mesh segment relative to the second portion of the mesh segment. In addition, the core wire may be configured to radially expand the mesh segment by axially moving the second portion of the mesh segment relative to the first portion of the mesh segment.

Abstract: Intraluminal and endovascular devices and methods of manufacturing intraluminal and endovascular devices may be provided. In one implementation, an intraluminal device may include a sheath having a flexible distal bending segment and a core wire arranged within the sheath. The core wire may include a distal end portion doubled back in a loop within the sheath such that the distal tip of the core wire is situated proximally from the loop. The intraluminal device may also include a movement restrictor within the sheath that is configured to limit axial movement of the distal tip of the core wire. Limiting the axial movement of the core wire distal tip may cause the loop of the core wire to buckle, resulting in a bend in the distal bending segment of the sheath, when a force is exerted on the core wire.

Abstract: In one exemplary embodiment, an endovascular device may include a hollow shaft having a proximal end and a distal end, and sized for insertion into a blood vessel. The endovascular device may also include a control line having a proximal end and a distal end, and extending through the hollow shaft. The endovascular device may also include an actuatable working element located proximate the distal end of the hollow shaft, and configured to receive an actuation force transmitted via the distal end of the control line. The endovascular device may further include an actuator configured to exert the actuation force on the proximal end of the control line, to thereby cause relative movement between the control line and the hollow shaft and to actuate the working element. The hollow shaft may also include a cable formed of a plurality of wound wires and including a proximal segment, at least one transition segment, and a distal segment.

Abstract: Intraluminal devices and methods for removing an obstruction from a blood vessel using an intraluminal device are provided. The intraluminal device can include a flexible shaft and an expandable wire mesh structure extending from the flexible shaft, the wire mesh structure including at least one first expandable section having a first wire arrangement pattern and at least one second expandable section having a second wire arrangement pattern different from the first wire arrangement pattern. In addition, interstices in the at least one first expandable section can differ in size from interstices in the at least one second expandable section.

Abstract: Intraluminal devices and methods of fabricating intraluminal devices may be provided. In one implementation, an intraluminal device may be formed of a plurality of wires and may include a distal coil, a proximal coil, and an expandable mesh segment positioned between the distal and proximal coils. The distal coil, proximal coil, and expandable mesh segment may be formed as a single, unitary structure, with at least one wire of the plurality of wires extending continuously from the proximal coil to the distal coil.

Abstract: Intraluminal devices and methods of fabricating intraluminal devices may be provided. In one implementation, an intraluminal device may be formed of a plurality of wires and may include a distal coil, a proximal coil, and an expandable mesh segment positioned between the distal and proximal coils. The proximal coil may include more wires of the plurality of wires than the distal coil and the expandable mesh segment. Due to the smaller number of wires forming the distal coil, the intraluminal device may be configured to have a soft and atraumatic distal tip and a more rigid proximal cable.

Abstract: Intraluminal and endovascular devices and methods of manufacturing intraluminal and endovascular devices may be provided. In one implementation, an intraluminal device may include a sheath having a flexible distal bending segment and a core wire arranged within the sheath. The core wire may include a distal end portion doubled back in a loop within the sheath such that the distal tip of the core wire is situated proximally from the loop. The intraluminal device may also include a movement restrictor within the sheath that is configured to limit axial movement of the distal tip of the core wire. Limiting the axial movement of the core wire distal tip may cause the loop of the core wire to buckle, resulting in a bend in the distal bending segment of the sheath, when a force is exerted on the core wire.

Abstract: An intraluminal guide wire may include an elongated shaft extending between a distal and a proximal end. The guide wire may include a user actuation segment positioned proximal to the proximal end of the shaft and configured for movement relative to the shaft. The guide wire may include a core wire affixed to the user actuation segment and the distal end of the shaft. The guide wire may also include an inner member having a proximal end situated at least partially within and fixed relative to the user actuation segment and a distal end situated partially within the shaft, the core wire passing through the inner member. The guide wire may be configured with a distal segment of the inner member within the shaft exhibiting a friction-based restraint on movement within the shaft. The friction-based restraint on movement may be a frictional force between the inner member and the shaft.