Patents by Inventor Ajay Thukral

Ajay Thukral has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180168448
    Abstract: Embodiments of a testing method for diabetics to optimize their administered insulin dosage comprise collecting sampling sets of biomarker data, each sampling set comprising a sufficient plurality of non-adverse sampling instances and each sampling instance comprising an acceptable biomarker reading at a single point in time recorded upon compliance with adherence criteria, determining a biomarker sampling parameter from each sampling set, comparing the biomarker sampling parameter to a target biomarker range, calculating an insulin adjustment parameter associated with the biomarker sampling parameter if the biomarker sampling parameter falls outside the target biomarker range, adjusting the insulin dosage by the insulin adjustment parameter if the biomarker sampling parameter falls outside the target biomarker range and the insulin dosage does not exceed maximum dosage, and exiting the testing method if the adjusted insulin dosage is optimized.
    Type: Application
    Filed: February 2, 2018
    Publication date: June 21, 2018
    Applicant: Roche Diabetes Care, Inc.
    Inventors: Steven Bousamra, Stefan Weinert, Juergen Rasch-Menges, P. Douglas Walling, Ajay Thukral, Heino Eikmeier, Birgit Kraeling, Karl Warner, Ulrich Porsch
  • Patent number: 9092553
    Abstract: A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: July 28, 2015
    Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Stefan Weinert, Ajay Thukral
  • Patent number: 8818782
    Abstract: A system for developing patient-specific therapies based on dynamic modeling of patient-specific physiology and method thereof are disclosed. The system includes software modules configured to provide access via a computer to one or more data collection protocols defining at least a type of patient-specific data to be collected and a manner in which the patient-specific data is to be collected, and to information from which one or more patient-specific models, configured to simulate one or more aspects of the patient's physiology, is developed. Another software module of the system is configured to provide access via the computer to one or more software tools that apply patient-specific data, collected according to the one or more data collection protocols, to the one or more patient specific models to determine therefrom one or more patient-specific therapies.
    Type: Grant
    Filed: May 12, 2008
    Date of Patent: August 26, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Ajay Thukral, Paul Galley, Siva Chittajallu, Stefan Weinert
  • Patent number: 8712748
    Abstract: A diagnosis, therapy and prognosis system (DTPS) and method thereof to help either the healthcare provider or the patient in diagnosing, treating and interpreting data are disclosed. The apparatus provides data collection based on protocols, and mechanism for testing data integrity and accuracy. The data is then driven through an analysis engine to characterize in a quantitative sense the metabolic state of the patient's body. The characterization is then used in diagnosing the patient, determining therapy, evaluating algorithm strategies and offering prognosis of potential use case scenarios.
    Type: Grant
    Filed: May 12, 2008
    Date of Patent: April 29, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Ajay Thukral, Paul Galley, Siva Chittajallu, Stefan Weinert
  • Patent number: 8679087
    Abstract: A therapy delivery system having an open architecture and method of providing thereof are disclosed. The present invention provides a therapy dosage module having a control algorithm that can be replaced with a predefined or independently defined control algorithm. The tools necessary to create and test such control algorithms in the therapy dosage module in a simulated environment before implementing it in a live therapy system are also disclosed.
    Type: Grant
    Filed: January 20, 2012
    Date of Patent: March 25, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Stefan Weinert, Ajay Thukral, Paul Galley, Siva Chittajallu, Steven Bousamra, James Long
  • Publication number: 20120197536
    Abstract: A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.
    Type: Application
    Filed: April 5, 2012
    Publication date: August 2, 2012
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Stefan Weinert, Ajay Thukral
  • Publication number: 20120116347
    Abstract: A therapy delivery system having an open architecture and method of providing thereof are disclosed. The present invention provides a therapy dosage module having a control algorithm that can be replaced with a predefined or independently defined control algorithm. The tools necessary to create and test such control algorithms in the therapy dosage module in a simulated environment before implementing it in a live therapy system are also disclosed.
    Type: Application
    Filed: January 20, 2012
    Publication date: May 10, 2012
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Stefan Weinert, Ajay Thukral, Paul Galley, Siva Chittajallu, Steven Bousamra, James Long
  • Patent number: 8175812
    Abstract: A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: May 8, 2012
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Stefan Weinert, Ajay Thukral
  • Patent number: 8123717
    Abstract: A therapy delivery system having an open architecture and method of providing thereof are disclosed. The present invention provides a therapy dosage module having a control algorithm that can be replaced with a predefined or independently defined control algorithm. The tools necessary to create and test such control algorithms in the therapy dosage module in a simulated environment before implementing it in a live therapy system are also disclosed.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: February 28, 2012
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Stefan Weinert, Ajay Thukral, Paul Galley, Siva Chittajallu, Steven Bousamra, James Long
  • Publication number: 20110196213
    Abstract: Methods for providing an estimated or predicted biological values in a sectioned display to assess the relative impact of a set of variables include collecting biological measurements, grouping the biological measurements based on the set of variables, evaluating the biological measurements to determine grouped estimated biological values or grouped predicted biological values, and providing the grouped estimated biological values or grouped predicted biological values within a plurality of sections in the sectioned display, wherein the plurality of sections correspond to the set of variables.
    Type: Application
    Filed: January 31, 2011
    Publication date: August 11, 2011
    Applicants: ROCHE DIAGNOSTICS OPERATIONS, INC., ROCHE DIAGNOSTICS GbmH
    Inventors: Ajay Thukral, Stefan Weinert, Abhishek Soni, Paul Galley, Alan Greenburg, Ildiko Amann-Zalan, Juergen Rasch-Menges
  • Patent number: 7941200
    Abstract: A system for determining drug administration information may comprise an input device providing for user input of feed forward information having a first parameter component and a second parameter component, a data storage device and a processor. The data storage device may have stored therein a map correlating values of the first and second parameters to drug administration information. The processor may be responsive to user input of the feed forward information to determine corresponding drug administration information according to the map.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: May 10, 2011
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Stefhan Weinert, Paul Galley, Ajay Thukral, Siva Chittajallu, Harvey Buck, Robin Wagner, Kym Marco, James R. Long, Steven Bousamra
  • Publication number: 20100330598
    Abstract: A method and system for providing both an estimated true mean blood glucose value and estimated glycated hemoglobin (HbA1C) value from spot blood glucose (bG) measurements are disclosed. The bG measurements and associated context of the bG measurement are collected at daily times specified by a structured sampling schema, and the collected bG measurements are weighted based on the associated context. The estimated true mean bG value and the estimate HbA1C value are then determined from the weighted measurements of the collected bG measurements. A computer program for implementing the method for providing both an estimated true mean blood glucose value and estimated glycated hemoglobin (HbA1C) value from spot blood glucose (bG) measurements is also disclosed.
    Type: Application
    Filed: June 26, 2009
    Publication date: December 30, 2010
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Ajay Thukral, Stefan Weinert, Zhengzheng Pan
  • Publication number: 20100331627
    Abstract: An adherence indication tool for chronic disease self-management and method thereof for measuring adherence or compliance to following or achieving prescribed therapy steps to achieve stated target goals for improved chronic disease self-management are disclosed.
    Type: Application
    Filed: June 26, 2009
    Publication date: December 30, 2010
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Ajay Thukral, Stefan Weinert, Robin Wagner, Maury Zivitz
  • Publication number: 20090326357
    Abstract: A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.
    Type: Application
    Filed: June 25, 2008
    Publication date: December 31, 2009
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Stefan Weinert, Ajay Thukral
  • Publication number: 20090006061
    Abstract: A system for developing patient-specific therapies based on dynamic modeling of patient-specific physiology and method thereof are disclosed. The system includes software modules configured to provide access via a computer to one or more data collection protocols defining at least a type of patient-specific data to be collected and a manner in which the patient-specific data is to be collected, and to information from which one or more patient-specific models, configured to simulate one or more aspects of the patient's physiology, is developed. Another software module of the system is configured to provide access via the computer to one or more software tools that apply patient-specific data, collected according to the one or more data collection protocols, to the one or more patient specific models to determine therefrom one or more patient-specific therapies.
    Type: Application
    Filed: May 12, 2008
    Publication date: January 1, 2009
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Ajay Thukral, Paul Galley, Siva Chittajallu, Stefan Weinert
  • Publication number: 20090006129
    Abstract: A diagnosis, therapy and prognosis system (DTPS) and method thereof to help either the healthcare provider or the patient in diagnosing, treating and interpreting data are disclosed. The apparatus provides data collection based on protocols, and mechanism for testing data integrity and accuracy. The data is then driven through an analysis engine to characterize in a quantitative sense the metabolic state of the patient's body. The characterization is then used in diagnosing the patient, determining therapy, evaluating algorithm strategies and offering prognosis of potential use case scenarios.
    Type: Application
    Filed: May 12, 2008
    Publication date: January 1, 2009
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Ajay Thukral, Paul Galley, Siva Chittajallu, Stefan Weinert
  • Publication number: 20090006133
    Abstract: A patient interface for a therapy system allows a patient to input information that characterizes at least one patient event or condition and from which therapy information can be determined. The patient interface may illustratively be formed by developing a patient model that is configured to simulate the patient's physiological response to the at least one patient event or condition, collecting patient-specific information over time that relates to actual occurrences of the at least one patient event or condition, and defining a graphical interface, based on the patient model and on the collected patient-specific information, that maps input from the patient of the information that characterizes the at least one patient event or condition to corresponding therapy information.
    Type: Application
    Filed: May 12, 2008
    Publication date: January 1, 2009
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Stefan Weinert, Ajay Thukral
  • Publication number: 20090005728
    Abstract: A therapy delivery system having an open architecture and method of providing thereof are disclosed. The present invention provides a therapy dosage module having a control algorithm that can be replaced with a predefined or independently defined control algorithm. The tools necessary to create and test such control algorithms in the therapy dosage module in a simulated environment before implementing it in a live therapy system are also disclosed.
    Type: Application
    Filed: May 15, 2008
    Publication date: January 1, 2009
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Stefan Weinert, Ajay Thukral, Paul Galley, Siva Chittajallu, Steven Bousamra, James Long
  • Publication number: 20070179434
    Abstract: A system for determining drug administration information may comprise an input device providing for user input of feed forward information having a first parameter component and a second parameter component, a data storage device and a processor. The data storage device may have stored therein a map correlating values of the first and second parameters to drug administration information. The processor may be responsive to user input of the feed forward information to determine corresponding drug administration information according to the map.
    Type: Application
    Filed: December 8, 2005
    Publication date: August 2, 2007
    Inventors: Stefan Weinert, Paul Galley, Ajay Thukral, Siva Chittajallu, Harvey Buck, Robin Wagner, Kym Marco, James Long, Stefan Bousamra
  • Publication number: 20060276771
    Abstract: A system providing for user intervention in a medical control arrangement may comprise a first user intervention mechanism responsive to user selection thereof to produce a first user intervention signal, a second user intervention mechanism responsive to user selection thereof to produce a second user intervention signal, and a processor executing a drug delivery algorithm forming part of the medical control arrangement. The processor may be responsive to the first user intervention signal to include an intervention therapy value in the execution of the drug delivery algorithm, and responsive to the second user intervention signal to exclude the intervention therapy value from the execution of the drug delivery algorithm. The medical control arrangement may be a diabetes control arrangement, the drug delivery algorithm may be an insulin delivery algorithm, and the intervention therapy value may be, for example, an intervention insulin quantity or an intervention carbohydrate quantity.
    Type: Application
    Filed: June 6, 2005
    Publication date: December 7, 2006
    Inventors: Paul Galley, Ajay Thukral, Siva Chittajallu, Robin Wagner, Stefan Weinert, Steven Bousamra