Patents by Inventor Ajit Parhi

Ajit Parhi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacterial efflux pump inhibitors
    Patent number: 11938114
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: March 26, 2024
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Yongzheng Zhang
  • Bacterial efflux pump inhibitors
    Patent number: 11826357
    Abstract: Disclosed herein are compounds of formula I and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: November 28, 2023
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Yi Yuan, Yongzheng Zhang, Yangsheng Sun
  • Therapeutic compounds and methods to treat infection
    Patent number: 11458121
    Abstract: Disclosed herein are compounds of formula I: or a salt thereof and compositions comprising a compound of formula I or a pharmaceutically acceptable salt thereof. Also disclosed herein are methods for treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I or a pharmaceutically acceptable salt thereof, alone or in combination with a bacterial efflux pump inhibitor.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: October 4, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Hye Yeon Sagong
  • Bacterial efflux pump inhibitors
    Patent number: 11180459
    Abstract: Disclosed herein are compounds of formula I and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: November 23, 2021
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Yongzheng Zhang, Yi Yuan, Yangsheng Sun
  • Antimicrobial agents
    Patent number: 11129814
    Abstract: The invention provides synthetic methods and synthetic intermediates that are useful for preparing the antibacterial compound:
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: September 28, 2021
    Assignee: TAXIS PHARMACEUTICALS, INC.
    Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
  • BACTERIAL EFFLUX PUMP INHIBITORS
    Publication number: 20210137881
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Application
    Filed: March 9, 2018
    Publication date: May 13, 2021
    Applicant: RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Yongzheng Zhang
  • INDOLE DERIVATIVES AS EFFLUX PUMP INHIBITORS
    Publication number: 20210094912
    Abstract: Disclosed herein are compounds of formula (I): and salts thereof. Also disclosed are compositions comprising compounds of formula I and compounds of formula I for use in treating or preventing bacterial infections.
    Type: Application
    Filed: March 9, 2018
    Publication date: April 1, 2021
    Applicant: RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Yi Yuan, Yongzheng Zhang, Yangsheng Sun
  • Bacterial efflux pump inhibitors
    Patent number: 10836706
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: November 17, 2020
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Edmond J. LaVoie, Ajit Parhi, Gifty A. Blankson, Liping Wang, Xiao Chen, Yongzheng Zhang, Malvika Kaul, Daniel S. Pilch
  • BACTERIAL EFFLUX PUMP INHIBITORS
    Publication number: 20200197382
    Abstract: Disclosed herein are compounds of formula I and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Application
    Filed: May 25, 2018
    Publication date: June 25, 2020
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Yi Yuan, Yongzheng Zhang, Yangsheng Sun
  • THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION
    Publication number: 20200155507
    Abstract: Disclosed herein are compounds of formula I: or a salt thereof and compositions comprising a compound of formula I or a pharmaceutically acceptable salt thereof. Also disclosed herein are methods for treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I or a pharmaceutically acceptable salt thereof, alone or in combination with a bacterial efflux pump inhibitor.
    Type: Application
    Filed: June 26, 2018
    Publication date: May 21, 2020
    Inventors: Edmond J. LaVoie, Ajit Parhi, Hye Yeon Sagong
  • BACTERIAL EFFLUX PUMP INHIBITORS
    Publication number: 20200140393
    Abstract: Disclosed herein are compounds of formula I and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Application
    Filed: March 9, 2018
    Publication date: May 7, 2020
    Applicant: RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Yongzheng Zhang, Yi Yuan, Yangsheng Sun
  • Bacterial efflux pump inhibitors
    Patent number: 10556854
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: February 11, 2020
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit Parhi, Malvika Kaul, Daniel S. Pilch
  • BACTERIAL EFFLUX PUMP INHIBITORS
    Publication number: 20190084919
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Application
    Filed: February 23, 2017
    Publication date: March 21, 2019
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit Parhi, Malvika Kaul, Daniel S. Pilch
  • BACTERIAL EFFLUX PUMP INHIBITORS
    Publication number: 20190055188
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Application
    Filed: February 23, 2017
    Publication date: February 21, 2019
    Inventors: Edmond J. LaVoie, Ajit Parhi, Gifty A. Blankson, Liping Wang, Xiao Chen, Yongzheng Zhang, Malvika Kaul, Daniel S. Pilch
  • ANTIMICROBIAL AGENTS
    Publication number: 20180338957
    Abstract: The invention provides synthetic methods and synthetic intermediates that are useful for preparing the antibacterial compound:
    Type: Application
    Filed: August 2, 2018
    Publication date: November 29, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, TAXIS PHARMACEUTICALS, INC.
    Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
  • Antimicrobial agents
    Patent number: 10071082
    Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: September 11, 2018
    Assignees: Rutgers, The State University of New Jersey, Taxis Pharmaceuticals, Inc.
    Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
  • ANTIMICROBIAL AGENTS
    Publication number: 20180179225
    Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.
    Type: Application
    Filed: August 3, 2017
    Publication date: June 28, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, TAXIS PHARMACEUTICALS, INC.
    Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
  • Therapeutic hydroxypyridinones, hydroxypyrimidinones and hydroxypyridazinones
    Patent number: 9932323
    Abstract: The invention provides compounds of formula I: and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: April 3, 2018
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Edmond J. Lavoie, Joseph David Bauman, Ajit Parhi, Hye Yeon Sagong, Disha Patel, Eddy Arnold, Kalyan Das, Suyambu Kesava Vijayan
  • Antimicrobial agents
    Patent number: 9822108
    Abstract: The invention provides methods of treating a bacterial infection in a mammal comprising administering to the mammal a substituted bicyclic heteroaromatic ring compound of formula I: wherein two of X1 to X8 are N and the remaining of X1 to X8 are CH; or a pharmaceutically acceptable salt thereof, as well as novel compounds of formula I and salts thereof and pharmaceutical compositions comprising a compound of formula I or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: November 21, 2017
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Malvika Kaul
  • THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES
    Publication number: 20170204083
    Abstract: The invention provides compounds of formula I: and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.
    Type: Application
    Filed: January 13, 2017
    Publication date: July 20, 2017
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LAVOIE, Joseph David BAUMAN, Ajit PARHI, Hye Yeon SAGONG, Disha PATEL, Eddy ARNOLD, Kalyan DAS, Suyambu Kesava VIJAYAN