Patents by Inventor Akie KAWAMURA

Akie KAWAMURA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9695112
    Abstract: Objects of the present invention are to provide an industrially applicable method for producing an optically active ?-amino acid in high yield and in a highly enantioselective manner, to provide a simple production method of an optically active ?,?-disubstituted ?-amino acid, and to provide an intermediate useful for the above production methods of an optically active ?-amino acid and an optically active ?,?-disubstituted ?-amino acid. The present invention provides a production method of an optically active ?-amino acid or a salt thereof, the production method comprising introducing a substituent into the ? carbon in the ?-amino acid moiety of a metal complex represented by the following Formula (1): by an alkylation reaction, an aldol reaction, the Michael reaction, or the Mannich reaction, and releasing an optically pure ?-amino acid enantiomer or a salt thereof by acid decomposition of the metal complex.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: July 4, 2017
    Assignee: HAMARI CHEMICALS, LTD.
    Inventors: Hiroki Moriwaki, Aki Kawashima, Ryosuke Takeda, Akie Kawamura, Vadim A. Soloshonok
  • Patent number: 9688612
    Abstract: An object of the present invention is to provide a method for producing an optically active amino acid in high yield and in a highly enantioselective manner, which method has fewer restrictions on the material that can be used as the substrate, and to provide, among others, a compound useful as a chiral auxiliary for the method.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: June 27, 2017
    Assignee: HAMARI CHEMICALS, LTD.
    Inventors: Hiroki Moriwaki, Ryosuke Takeda, Akie Kawamura, Aki Kawashima, Vadim A. Soloshonok
  • Publication number: 20160102045
    Abstract: Objects of the present invention are to provide an industrially applicable method for producing an optically active ?-amino acid in high yield and in a highly enantioselective manner, to provide a simple production method of an optically active ?,?-disubstituted ?-amino acid, and to provide an intermediate useful for the above production methods of an optically active ?-amino acid and an optically active ?,?-disubstituted ?-amino acid. The present invention provides a production method of an optically active ?-amino acid or a salt thereof, the production method comprising introducing a substituent into the ? carbon in the ?-amino acid moiety of a metal complex represented by the following Formula (1): by an alkylation reaction, an aldol reaction, the Michael reaction, or the Mannich reaction, and releasing an optically pure ?-amino acid enantiomer or a salt thereof by acid decomposition of the metal complex.
    Type: Application
    Filed: March 27, 2014
    Publication date: April 14, 2016
    Inventors: Hiroki Moriwaki, Aki Kawashima, Ryosuke Takeda, Akie Kawamura, Vadim A. Soloshonok
  • Publication number: 20150321994
    Abstract: An object of the present invention is to provide a method for producing an optically active amino acid in high yield and in a highly enantioselective manner, which method has fewer restrictions on the material that can be used as the substrate, and to provide, among others, a compound useful as a chiral auxiliary for the method.
    Type: Application
    Filed: December 17, 2013
    Publication date: November 12, 2015
    Applicant: Hamari Chemicals, Ltd. 4-29
    Inventors: Hiroki MORIWAKI, Ryosuke TAKEDA, Akie KAWAMURA, Aki KAWASHIMA, Vadim A. SOLOSHONOK