Patents by Inventor Akiko Shimatani

Akiko Shimatani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9327050
    Abstract: A hemostatic material as a high-performance medical material is described, which is capable of stopping bleeding in short time and is easy to handle and produce. The hemostatic material contains a nano-fiber that contains: a polymer, and a polypeptide having a peptide fragment represented by formula (1): -(Pro-Y-Gly)n-??(1) wherein Y represents hydroxyproline or proline, and n represents an integer ranging from 5 to 9000.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: May 3, 2016
    Assignee: JNC CORPORATION
    Inventors: Hisatoshi Kobayashi, Dohiko Terada, Masami Todokoro, Akiko Shimatani, Yukinori Kataoka
  • Patent number: 8969522
    Abstract: An object is to provide a method for producing an ever-larger molecular weight collagen-like polypeptide single strand. Another object is to provide a method for controlling a molecular weight of a product to be obtained in desired magnitude upon producing a collagen-like polypeptide single strand. A solution is a method for producing a polypeptide including a step for allowing a condensation reaction of peptide oligomers represented by any one of formulas (1) to (3) (SEQ ID No:1 to SEQ ID No:3), wherein the condensation reaction is carried out in an aqueous solvent containing a phosphate ion in the range of 0 M to less than 0.01 M in the presence of a condensing agent, or a condensing agent and a condensing auxiliary: H-(Pro-Y-Gly)n-OH??(1); H-(Y-Gly-Pro)n-OH??(2); and H-(Gly-Pro-Y)n-OH??(3); wherein, in formulas (1) to (3), Y is hydroxyproline or proline, and n is an integer from 1 to 10.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: March 3, 2015
    Assignee: JNC Corporation
    Inventors: Akihiro Uchida, Shuji Sasaki, Akiko Shimatani, You Umebayashi, Kazushi Ishida
  • Patent number: 8735352
    Abstract: An objective of the invention is to provide an adsorbent allowing purification of a blood coagulation factor or a cell adhesion factor under mild conditions, according to simple procedures, and at a low cost and safely while having a high affinity and a high resistance to deterioration, and a method for purifying the blood coagulation factor or the cell adhesion factor; a solution is to apply a polypeptide having peptide fragments represented by formula (1) as the adsorbent for the blood coagulation factor or the cell adhesion factor, and to purify the blood coagulation factor or the cell adhesion factor using the adsorbent: -(Pro-Hyp-Gly)n- Wherein, in formula (1), n is an integer from 2 to 9,000.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: May 27, 2014
    Assignee: JNC Corporation
    Inventors: Masami Todokoro, Akiko Shimatani
  • Publication number: 20140128573
    Abstract: An object is to provide a method for producing an ever-larger molecular weight collagen-like polypeptide single strand. Another object is to provide a method for controlling a molecular weight of a product to be obtained in desired magnitude upon producing a collagen-like polypeptide single strand. A solution is a method for producing a polypeptide including a step for allowing a condensation reaction of peptide oligomers represented by any one of formulas (1) to (3) (SEQ ID No:1 to SEQ ID No:3), wherein the condensation reaction is carried out in an aqueous solvent containing a phosphate ion in the range of 0 M to less than 0.01 M in the presence of a condensing agent, or a condensing agent and a condensing auxiliary: H-(Pro-Y-Gly)n-OH??(1); H-(Y-Gly-Pro)n-OH??(2); and H-(Gly-Pro-Y)n-OH??(3); wherein, in formulas (1) to (3), Y is hydroxyproline or proline, and n is an integer from 1 to 10.
    Type: Application
    Filed: June 28, 2013
    Publication date: May 8, 2014
    Applicant: JNC CORPORATION
    Inventors: AKIHIRO UCHIDA, SHUJI SASAKI, AKIKO SHIMATANI, YOU UMEBAYASHI, KAZUSHI ISHIDA
  • Publication number: 20140017295
    Abstract: A medical material having high hemostatic ability, which is easy to handle and shows improved productivity, is described. A hemostatic material comprising a polypeptide having a peptide fragment represented by General Formula (1) below: -(Pro-Y-Gly)n-??(1) [wherein in General Formula (1), Y represents hydroxyproline or proline, and n represents an integer of 74 to 171].
    Type: Application
    Filed: July 10, 2013
    Publication date: January 16, 2014
    Inventors: AKIKO SHIMATANI, HIROAKI WAKAMOTO, ERI IWAMOTO
  • Publication number: 20130253099
    Abstract: With respect to synthetic collagen that has so far been difficult to be nano-fiberized, a method for producing uniform and long fibrous nano-fibers containing a synthetic collagen is described. The nano-fibers contain a polypeptide having a peptide fragment represented by Formula (1): -(Pro-Y-Gly)n??(1), wherein Y represents hydroxyproline or proline, and n is an integar ranging from 5 to 9000. The producing method includes a step of preparing a spinning solution containing the polypeptide and a polymer, and a step of spinning with an electrospinning method using the spinning solution.
    Type: Application
    Filed: March 22, 2013
    Publication date: September 26, 2013
    Applicant: JNC CORPORATION
    Inventors: HISATOSHI KOBAYASHI, DOHIKO TERADA, MASAMI TODOKORO, AKIKO SHIMATANI, YUKINORI KATAOKA
  • Publication number: 20130251780
    Abstract: A hemostatic material as a high-performance medical material is described, which is capable of stopping bleeding in short time and is easy to handle and produce. The hemostatic material contains a nano-fiber that contains: a polymer, and a polypeptide having a peptide fragment represented by formula (1): -(Pro-Y-Gly)n- ??(1) wherein Y represents hydroxyproline or proline, and n represents an integer ranging from 5 to 9000.
    Type: Application
    Filed: March 22, 2013
    Publication date: September 26, 2013
    Applicant: JNC CORPORATION
    Inventors: HISATOSHI KOBAYASHI, DOHIKO TERADA, MASAMI TODOKORO, AKIKO SHIMATANI, YUKINORI KATAOKA
  • Publication number: 20060057688
    Abstract: Vitamin K2 is separated from a cultured product of a Bacillus bacterium such as Bacillus natto by insolubilizing vitamin K2 contained in the cultured product using a metal ion of bivalent or more and separating the insolubilized vitamin K2 from the cultured product.
    Type: Application
    Filed: August 29, 2005
    Publication date: March 16, 2006
    Inventors: Akiko Shimatani, Toshiharu Iwata, Mototake Tsutsui