Abstract: In an embodiment, an object of the present invention is to provide a double-stranded nucleic acid complex having a novel structure. In an embodiment, the present invention relates to a nucleic acid complex comprising a first nucleic acid strand and a second nucleic acid strand, wherein said first nucleic acid strand: (1) is capable of hybridizing to at least a part of a target transcriptional product; (2) has an antisense effect on the target transcriptional product; and (3) is a gapmer comprising a central region, and a 5? wing region and a 3? wing region, said second nucleic acid strand comprises at least one sugar-unmodified central region (first exposed region) consisting of one sugar-unmodified ribonucleoside or two or three contiguous sugar-unmodified ribonucleosides linked by an internucleoside bond, which is or are complementary to a part of said first nucleic acid strand, and said first nucleic acid strand is annealed to said second nucleic acid strand.

Abstract: A method of constructing a stainless-steel floor on a floor bed includes providing support members on the floor bed, placing a stainless-steel plate on the support members; and bonding the stainless-steel plate to the floor bed by using mortar to fill the space between the stainless-steel plate and the floor bed, or by using adhesive.

Abstract: A method of constructing a stainless-steel floor on a floor bed includes providing support members on the floor bed, placing a stainless-steel plate on the support members; and bonding the stainless-steel plate to the floor bed by using mortar to fill the space between the stainless-steel plate and the floor bed, or by using adhesive.

Abstract: A column base structure having connected a pair of column-base metal fittings to the lower part of a column consisting of a pair of main column members disposed at predetermined intervals and connecting members disposed in such a manner as to integrally connect the main column members; the column base metal fittings being fixedly fitted to a concrete foundation via anchor bolts and nuts; characterized in that a horizontal member having a predetermined cross-sectional area is integrally and fixedly fitted between the main column members in the vicinity of the column base metal fitting.

Abstract: A column/beam joint structure, made of steel members, in which a reinforcing member formed into a flat plate or into a strip shape so as to surround the outer periphery of the flange is interposed between a flange having a vertical plane constituting the column and a base plate constituting a connector fixedly fitted to an end of a beam. The flange, the reinforcing member and the connector are integrally joined together via a connecting fastener member.

Abstract: A method of connecting beams having an H-shaped section to a column having an H-shaped section of a steel frame construction with upper and lower flange fittings. The flange fitting comprises a substantially rectangular base plate to be connected to the column having centrally a continuous thicker portion from which the base plate is tapered toward opposite ends of the base plate, a supporting plate projecting from the thicker portion for supporting a flange of the beam and a reinforcement on the base plate forming a T-shaped portion with the supporting plate. First the supporting plate of the upper flange fitting is secured to one end of an upper flange of the beam in end-to-end relationship and the base plate of the lower flange fitting is bolted in position to the column.

Abstract: Fittings for connecting columns and beams of a steel frame construction comprise an upper flange fitting and a lower flange fitting. The upper flange fitting comprises a substantially rectangular base plate to be bolted to a web of the column and protrusions extending from the base plate to be welded to an upper flange and a web of the beam. The lower flange fitting comprises a substantially rectangular base plate to be bolted to the web of the column and a horizontal plate projecting from the base plate to be bolted to a lower flange of the beam.