Patents by Inventor Akira Okano

Akira Okano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-manifold data structure based NC machining simulation system and method thereof
    Patent number: 5561601
    Abstract: Use of a non-manifold data structure enables retention of not only the interfaces between an entity in the process of being cut and a non-entity, but also the interfaces between entities or non-entities. These interfaces include the surfaces of substances (the boundaries between an entity and a non-entity) at intermediate points in time during a machining process represented by a series of Boolean operations, and the final or in-process interfaces obtained when machining (Boolean operations) is performed in a different sequence, and hence procedures following this method enable simulation to be retried at a low computation cost after a machining procedure is modified.
    Type: Grant
    Filed: October 21, 1994
    Date of Patent: October 1, 1996
    Assignee: International Business Machines Corporation
    Inventors: Keisuke Inoue, Hiroshi Masuda, Akira Okano
  • Recombinant process of producing non-glycosylated B-cell defferentiation factor
    Patent number: 5541088
    Abstract: A purified human B-cell differentiation factor (BCDF) which does not have a natural signal peptide attached to the N-terminal thereof, DNA encoding the BCDF, transformed cells containing such DNA, a process for producing and obtaining the BCDF, and compositions containing the BCDF are disclosed.
    Type: Grant
    Filed: September 21, 1994
    Date of Patent: July 30, 1996
    Assignees: Ajinomoto Co., Inc., Tadamitsu Kishimoto
    Inventors: Tadamitsu Kishimoto, Toshio Hirano, Hiroshi Matsui, Yoshiyuki Takahara, Yukio Akiyama, Akira Okano
  • Use of recombinant B-cell differentiation factor for augmenting antibody production and stimulating bone marrow proliferation
    Patent number: 5362489
    Abstract: A purified human B-cell differentiation factor (BCDF) which does not have a natural signal peptide attached to the N-terminal thereof, DNA encoding the BCDF, transformed cells containing such DNA, a process for producing and obtaining the BCDF, compositions containing the BCDF and various therapeutic uses are disclosed.
    Type: Grant
    Filed: May 4, 1992
    Date of Patent: November 8, 1994
    Assignees: Ajinomoto Co., Inc., Tadamitsu Kishimoto
    Inventors: Tadamitsu Kishimoto, Toshio Hirano, Hiroshi Matsui, Yoshiyuki Takahara, Yukio Akiyama, Akira Okano
  • Method of treating thrombocytopenia using human BCDF in combination with IL-3
    Patent number: 5310550
    Abstract: Thrombocytopenia is treated by administering a subject suffering from thrombocytopenia a composition containing human B cell differentiation activity in combination with IL-3.
    Type: Grant
    Filed: January 9, 1992
    Date of Patent: May 10, 1994
    Assignees: Ajinomoto Co., Inc., Tadamitsu Kishimoto
    Inventors: Tadamitsu Kishimoto, Toshio Hirano, Hideo Kimura, Toshiyuki Ishibashi, Yukio Akiyama, Akira Okano
  • Composition and method for supporting bone marrow transplantation
    Patent number: 5186931
    Abstract: A composition and a method for supporting bone marrow transplantation are disclosed. The composition comprises a therapeutically acceptable amount of human B cell differentiation factor, or its biological equivalent, optionally in combination with an auxiliary agent selected from IL-1, IL-3, IL-4, IL-5, G-CSF, GM-CSF, and M-CSF. The composition also promotes the proliferation of hematopoietic cells in vitro.
    Type: Grant
    Filed: June 15, 1989
    Date of Patent: February 16, 1993
    Assignees: Ajinomoto Co., Inc., Tadamitsu Kishimoto
    Inventors: Tadamitsu Kishimoto, Toshio Hirano, Yukio Akiyama, Akira Okano, Hiroshi Matsui, Yoshiyuki Takahara
  • Method for treating thrombocytopenia
    Patent number: 5126325
    Abstract: Thrombocytopenia is treated by administering to a subject a therapeutic amount of human B cell differentiation factor or its biological equivalent.
    Type: Grant
    Filed: January 10, 1990
    Date of Patent: June 30, 1992
    Assignees: Ajinomoto Co., Inc., Tadamitsu Kishimoto
    Inventors: Tadamitsu Kishimoto, Toshio Hirano, Hideo Kimura, Toshiyuki Ishibashi, Yukio Akiyama, Akira Okano