Patents by Inventor Akitaka Nakane

Akitaka Nakane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9540617
    Abstract: A modified polynucleotide has a different base sequence in at least one codon from a wild-type base sequence encoding a horseradish peroxidase polypeptide. The usage frequency of the modified codon of the polynucleotide corresponds to the codon usage frequencies of three filamentous fungal species in Humicola, Aspergillus, and Trichoderma. The polynucleotide is capable of expressing the polypeptide to be encoded in a filamentous fungus.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: January 10, 2017
    Assignee: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Fumikazu Yokoyama, Kaoru Okakura, Atsushi Inoue, Koichiro Murashima, Toshiaki Nagasato, Koji Yanai, Akitaka Nakane
  • Publication number: 20160367585
    Abstract: The present invention relates to novel aminoglycoside antibiotics, a process for producing the same, and pharmaceutical use thereof. More specifically, the present invention relates to compounds represented by formula (I), a process for producing the same, and use of the same as antimicrobial agents. wherein R represents amino or hydroxyl.
    Type: Application
    Filed: September 6, 2016
    Publication date: December 22, 2016
    Inventors: Naomi SUMIDA, Koji YANAI, Masato TANI, Takayoshi FUKUSHIMA, Yasumasa OTA, Shuichi GOMI, Akitaka NAKANE
  • Patent number: 9469863
    Abstract: The present invention relates to novel aminoglycoside antibiotics, a process for producing the same, and pharmaceutical use thereof. More specifically, the present invention relates to compounds represented by formula (I), a process for producing the same, and use of the same as antimicrobial agents. wherein R represents amino or hydroxyl.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: October 18, 2016
    Assignee: MEIJI SEIKA KAISHA, LTD.
    Inventors: Naomi Sumida, Koji Yanai, Masato Tani, Takayoshi Fukushima, Yasumasa Ota, Shuichi Gomi, Akitaka Nakane
  • Publication number: 20150140574
    Abstract: A modified polynucleotide has a different base sequence in at least one codon from a wild-type base sequence encoding a horseradish peroxidase polypeptide. The usage frequency of the modified codon of the polynucleotide corresponds to the codon usage frequencies of three filamentous fungal species in Humicola, Aspergillus, and Trichoderma. The polynucleotide is capable of expressing the polypeptide to be encoded in a filamentous fungus.
    Type: Application
    Filed: May 30, 2013
    Publication date: May 21, 2015
    Applicant: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Fumikazu Yokoyama, Kaoru Okakura, Atsushi Inoue, Koichiro Murashima, Toshiaki Nagasato, Koji Yanai, Akitaka Nakane
  • Patent number: 8257955
    Abstract: A novel endoglucanase PPCE derived from Penicillium pinophilum, a cellulase preparation containing the endoglucanase PPCE, and a method of treating a cellulose-containing fabric utilizing the endoglucanase PPCE or the cellulase preparation, are disclosed. The endoglucanase PPCE is highly active to a fabric, and has a low optimum temperature and a strongly acidic optimum pH.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: September 4, 2012
    Assignee: Meiji Seika Pharma Co., Ltd.
    Inventors: Tatsuki Moriya, Akitaka Nakane, Goh Tsujiuchi, Takayoshi Fukushima
  • Publication number: 20110034405
    Abstract: The present invention relates to novel aminoglycoside antibiotics, a process for producing the same, and pharmaceutical use thereof. More specifically, the present invention relates to compounds represented by formula (I), a process for producing the same, and use of the same as antimicrobial agents. wherein R represents amino or hydroxyl.
    Type: Application
    Filed: December 1, 2008
    Publication date: February 10, 2011
    Inventors: Naomi Sumida, Koji Yanai, Masato Tani, Takayoshi Fukushima, Yasumasa Ota, Shuichi Gomi, Akitaka Nakane
  • Publication number: 20100098807
    Abstract: A novel endoglucanase PPCE derived from Penicillium pinophilum, a cellulase preparation containing the endoglucanase PPCE, and a method of treating a cellulose-containing fabric utilizing the endoglucanase PPCE or the cellulase preparation, are disclosed. The endoglucanase PPCE is highly active to a fabric, and has a low optimum temperature and a strongly acidic optimum pH.
    Type: Application
    Filed: March 12, 2008
    Publication date: April 22, 2010
    Applicant: MEIJI SEIKA KAISHA, LTD.
    Inventors: Tatsuki Moriya, Akitaka Nakane, Goh Tsujiuchi, Takayoshi Fukushima
  • Patent number: 7655449
    Abstract: An object of the present invention is to provide a ?-fructofuranosidase variant whose reaction specificity is improved to be suitable for the production of fructooligosaccharides. According to the present invention, there is provided a ?-fructofuranosidase variant consisting of a mutated amino acid sequence of SEQ ID NO: 2 or a mutated homologue thereof, which has mutations at specific amino acid residues.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: February 2, 2010
    Assignee: Meiji Seika Kaisha Ltd.
    Inventors: Hirofumi Nakamura, Akitaka Nakane, Hidetoshi Kubota
  • Patent number: 7595182
    Abstract: A novel endoglucanase derived from Staphylotrichum coccosporum, a polynucleotide encoding the endoglucanase, and a cellulase preparation containing the endoglucanase are disclosed. The endoglucanase or cellulase preparation is available for a washing use or fabric processing, such as a color clarification of a cellulose-containing fabric, a reduction of fuzz, an improvement of the touch feel and appearance of the fabric, providing a localized color change to the fabric, or a reduction of stiffness.
    Type: Grant
    Filed: October 22, 2004
    Date of Patent: September 29, 2009
    Assignee: Meiji Seika Kaisha, Ltd.,
    Inventors: Jinichiro Koga, Yuko Baba, Akitaka Nakane, Satoshi Hanamura, Tomoko Nishimura, Shuichi Gomi, Hidetoshi Kubota, Toshiaki Kono
  • Patent number: 7445922
    Abstract: This invention relates to a protein that is a Zygomycetes-derived endoglucanase lacking the cellulose-binding domain and exhibits endoglucanase activity, and a method for using the same. This invention can enhance effects of an endoglucanase enzyme on fabric treatment such as reduction of fuzzing, improvement in feel and appearance, color clarification, partial color change, and softening of cellulose-containing fabrics and on performance improvement in the deinking of waste paper and drainage of paper pulp.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: November 4, 2008
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Akitaka Nakane, Yuko Baba, Jinichiro Koga, Hidetoshi Kubota
  • Publication number: 20080187970
    Abstract: An object of the present invention is to provide a ?-fructofuranosidase variant whose reaction specificity is improved to be suitable for the production of fructooligosaccharides. According to the present invention, there is provided a ?-fructofuranosidase variant consisting of a mutated amino acid sequence of SEQ ID NO: 2 or a mutated homologue thereof, which has mutations at specific amino acid residues.
    Type: Application
    Filed: March 4, 2005
    Publication date: August 7, 2008
    Applicant: MEIJI SEIKA KAISHA LTD.
    Inventors: Hirofumi Nakamura, Akitaka Nakane, Hidetoshi Kubota
  • Publication number: 20070111278
    Abstract: A novel endoglucanase derived from Staphylotrichum coccosporum, a polynucleotide encoding the endoglucanase, and a cellulase preparation containing the endoglucanase are disclosed. The endoglucanase or cellulase preparation is available for a washing use or fabric processing, such as a color clarification of a cellulose-containing fabric, a reduction of fuzz, an improvement of the touch feel and appearance of the fabric, providing a localized color change to the fabric, or a reduction of stiffness.
    Type: Application
    Filed: October 22, 2004
    Publication date: May 17, 2007
    Inventors: Jinichiro Koga, Yuko Baba, Akitaka Nakane, Satoshi Hanamura, Tomoko Nishimura, Shuichi Gomi, Hidetoshi Kubota, Toshiaki Kono
  • Patent number: 7138263
    Abstract: There is provided an endoglucanase enzyme, which is useful for reducing fuzz of regenerated cellulose-containing fabrics, improving the touch and appearance, color clarification, localized variation in color, reducing stiffness and using it as components of a detergent, as well as deinking waste paper and improving freeness of paper pulp. A cDNA coding for the endoglucanase enzyme NCE5 was cloned and its DNA sequence and amino acid sequence derived from it were determined.
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: November 21, 2006
    Assignee: Meiji Seika Kabushiki Kaisha
    Inventors: Koichiro Murashima, Naomi Sumida, Akitaka Nakane, Koji Yanai, Tomoko Nishimura, Jinichiro Koga, Takeshi Murakami, Toshiaki Kono
  • Patent number: 7138261
    Abstract: A cellulase preparation comprising an endoglucanase derived from Zygomycetes, a cellulose-binding-domain-deleted endoglucanase, or a modified or homologous protein thereof, together with a reducing agent is disclosed. Further, a method of treating cellulose-containing fabric, comprising the step of treating the fabric with the cellulase preparation to improve a property of the fabric, a method of deinking waste paper, comprising the step of treating the waste paper with the cellulase preparation. together with a deinking agent, and a method of improving freeness of paper pulp, comprising the step of treating the paper pulp with the cellulase preparation, are disclosed.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: November 21, 2006
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Akitaka Nakane, Jinichiro Koga, Hidetoshi Kubota
  • Patent number: 7109013
    Abstract: The present invention relates to a cellulase preparation comprising nonionic surfactants together with endoglucanases derived from Zygomycetes; a detergent composition comprising the above cellulase preparation with detergent components; a method of treating fabric which comprises treating cellulose-containing fabric with the above cellulase preparation so as to improve the properties of the fabric; a method of deinking waster paper which comprises a step of treating waste paper with the above cellulase preparation together with a deinking agent; and a method of improving the freeness of paper pulp which comprises a step of treating paper pulp with the above cellulase preparation.
    Type: Grant
    Filed: November 12, 2001
    Date of Patent: September 19, 2006
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Jinichiro Koga, Akitaka Nakane, Yuko Baba, Toshiaki Kono
  • Patent number: 6921655
    Abstract: It is an object of the present invention to provide enzymes that have high endoglucanase activity and yet exhibit high activity even under alkaline conditions, and genes encoding the same. The enzyme according to the invention has the following properties: a) exhibiting endoglucanase activity; and b) capable of completely removing fuzz from regenerated cellulose fabrics at a concentration of 1 mg of the protein/L or below. The enzyme of the invention having endoglucanase activity is a protein comprising the amino acid sequence as shown in SEQ ID NO: 1, 3, 5, 7, 9 or 11; a modified protein thereof exhibiting endoglucanase activity; or a homologue of the protein or the modified protein.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: July 26, 2005
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Yuko Nakamura, Tatsuki Moriya, Yuko Baba, Koji Yanai, Naomi Sumida, Tomoko Nishimura, Kouichirou Murashima, Akitaka Nakane, Takashi Yaguchi, Jinichiro Koga, Takeshi Murakami, Toshiaki Kono
  • Publication number: 20050143275
    Abstract: There is provided an endoglucanase enzyme, which is useful for reducing fuzz of regenerated cellulose-containing fabrics, improving the touch and appearance, color clarification, localized variation in color, reducing stiffness and using it as components of a detergent, as well as deinking waste paper and improving freeness of paper pulp. A cDNA coding for the endoglucanase enzyme NCE5 was cloned and its DNA sequence and amino acid sequence derived from it were determined.
    Type: Application
    Filed: May 22, 2001
    Publication date: June 30, 2005
    Inventors: Koichoro Murashima, Naomi Sumida, Akitaka Nakane, Koji Yanai, Tomoko Nishimura, Jinichiro Koga, Takeshi Murakami, Toshiaki Kono
  • Publication number: 20050102762
    Abstract: A cellulase preparation comprising an endoglucanase derived from Zygomycetes, a cellulose-binding-domain-deleted endoglucanase, or a modified or homologous protein thereof, together with a reducing agent is disclosed. Further, a method of treating cellulose-containing fabric, comprising the step of treating the fabric with the cellulase preparation to improve a property of the fabric, a method of deinking waste paper, comprising the step of treating the waste paper with the cellulase preparation. together with a deinking agent, and a method of improving freeness of paper pulp, comprising the step of treating the paper pulp with the cellulase preparation, are disclosed.
    Type: Application
    Filed: December 17, 2002
    Publication date: May 19, 2005
    Inventors: Akitaka Nakane, Jinichiro Koga, Hidetoshi Kubota
  • Publication number: 20040043400
    Abstract: This invention relates to a protein that is a Zygomycetes-derived endoglucanase lacking the cellulose-binding domain and exhibits endoglucanase activity, and a method for using the same. This invention can enhance effects of an endoglucanase enzyme on fabric treatment such as reduction of fuzzing, improvement in feel and appearance, color clarification, partial color change, and softening of cellulose-containing fabrics and on performance improvement in the deinking of waste paper and drainage of paper pulp.
    Type: Application
    Filed: May 20, 2003
    Publication date: March 4, 2004
    Inventors: Akitaka Nakane, Yuko Baba, Jinichiro Koga, Hidetoshi Kubota
  • Publication number: 20040038841
    Abstract: The present invention relates to a cellulase preparation comprising nonionic surfactants together with endoglucanases derived from Zygomycetes; a detergent composition comprising the above cellulase preparation with detergent components; a method of treating fabric which comprises treating cellulose-containing fabric with the above cellulase preparation so as to improve the properties of the fabric; a method of deinking waster paper which comprises a step of treating waste paper with the above cellulase preparation together with a deinking agent; and a method of improving the freeness of paper pulp which comprises a step of treating paper pulp with the above cellulase preparation.
    Type: Application
    Filed: May 8, 2003
    Publication date: February 26, 2004
    Inventors: Jinichiro Koga, Akitaka Nakane, Yuko Baba, Toshiaki Kono