Abstract: A needle safety device includes a sleeve having proximal and distal portions separated by a radially-inwardly projecting ledge. A ring in the proximal portion is movable between a first position spaced from the ledge, and a second position adjacent to or abutting the ledge. A shield with at least one radially deformable tab receives the syringe and is movable in the sleeve between an initial position with the tab adjacent to or abutting the ledge, an injection position with the tab spaced from the ledge, and a protection position with the tab located distally from the ledge. The tab, during movement between initial and injection positions, deforms inwardly and traverses the inner surface of the ring, and during movement between injection and protection positions, translates with the ring from the first to the second position, and subsequently deforms inwardly and traverses the inner surface of the ring and the ledge.

Abstract: A needle safety device includes a sleeve having proximal and distal portions separated by a radially-inwardly projecting ledge. A ring in the proximal portion is movable between a first position spaced from the ledge, and a second position adjacent to or abutting the ledge. A shield with at least one radially deformable tab receives the syringe and is movable in the sleeve between an initial position with the tab adjacent to or abutting the ledge, an injection position with the tab spaced from the ledge, and a protection position with the tab located distally from the ledge. The tab, during movement between initial and injection positions, deforms inwardly and traverses the inner surface of the ring, and during movement between injection and protection positions, translates with the ring from the first to the second position, and subsequently deforms inwardly and traverses the inner surface of the ring and the ledge.

Abstract: The disclosure relates to a method for preparing a compound of formula (I), wherein P1 and P2 are groups protecting the carboxylic acid and oxyamine functions, starting from pyroglutamic acid (S). The disclosure also relates to novel intermediates.

Abstract: The disclosure relates to a method for preparing a compound of formula (I), wherein P1 and P2 are groups protecting the carboxylic acid and oxyamine functions, starting from pyroglutamic acid (S). The disclosure also relates to novel intermediates.

Abstract: The disclosure relates to a method for preparing a compound of formula (I), wherein P1 and P2 are groups protecting the carboxylic acid and oxyamine functions, starting from pyroglutamic acid (S). The disclosure also relates to novel intermediates.

Abstract: A process for the preparation of compounds of formula (I) in which R1, R2, R3 and n are defined as indicated in the description, use of said compounds as intermediates for the preparation of estrogen derivatives as well as the intermediates of this process.

Abstract: A process for the preparation of compounds of formula (I) 1

Abstract: Novel tricyclic compounds of formula I as defined in the specification, a process for their preparation and their use for the preparation of optically active or racemic colchicine and thiocolchicine derivatives.

Abstract: A compound of the formula ##STR1## wherein alc.sub.1, alc.sub.2 and alc.sub.3 are alkyl of up to 8 carbon atoms, n is an integer from 0 to 8, R.sub.1 and R.sub.

Abstract: A subject of the invention is the compounds of formula (I): ##STR1## in which OR.sub.1, OR.sub.2 and OR.sub.3 represent hydroxyl radicals blocked in the form of easily cleavable radicals.The compounds of formula (I) can be used to prepare antibiotic products.

Abstract: Novel tricyclic compounds of formula I as defined in the specification, a process for their preparation and their use for the preparation of optically active or racemic colchicine and thiocolchicine derivatives.

Abstract: Novel tricyclic compounds of formula I as defined in the specification, a process for their preparation and their use for the preparation of optically active or racemic colchicine and thiocolchicine derivatives.