Patents by Inventor Alain Tedgui

Alain Tedgui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090215697
    Abstract: The present invention concern a composition or a patch adapted for the prophylactic or therapeutic treatment by continuous subcutaneous administration of a subject suffering from atherosclerosis, comprising an effective amount of at least one epitope derived from a protein present in the atherosclerotic plaque, whereby administration of said at least one epitope to said subject induces a specific regulatory immune response, preferably a Treg response.
    Type: Application
    Filed: January 4, 2006
    Publication date: August 27, 2009
    Inventors: Alain Tedgui, Ziad Mallat
  • Publication number: 20080107663
    Abstract: The present invention relates to a method of treating or preventing atherosclerosis comprising administering to a mammal in need of such a treatment a) an antigen which has been used to activate in vitro a Tri cell population originating from said mammal, and b) the TO cell population activated by said antigen, said TO cell population being obtained from a CD4+ T lymphocyte population of said mammal.
    Type: Application
    Filed: August 11, 2004
    Publication date: May 8, 2008
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), TXCELL
    Inventors: Herve Groux, Alain Tedgui, Ziad Mallat, Valerie Brun
  • Publication number: 20070249008
    Abstract: The present invention relates to a method for determining an increased risk of mortality or of a cardiac and/or vascular event in a patient, comprising: determining the sPLA2 activity of said patient, comparing said activity to a predetermined value, a higher sPLA2 activity of said patient as compared to said predetermined value being indicative of an increased risk of mortality or of a cardiac and/or vascular event.
    Type: Application
    Filed: July 15, 2005
    Publication date: October 25, 2007
    Inventors: Ziad Mallat, Alain Tedgui, Phillippe Steg, Jean-Marie Freyssienet, Joelle Benessiano
  • Publication number: 20070116674
    Abstract: The invention relates to the use of cells of a medullary or extra-medullary white adipose tissue, in particular of an extra-medullary stromal vascular fraction (SVF) and/or mature dedifferentiated adipocytes of any origin for initiating the formation of a functional vascularisation.
    Type: Application
    Filed: September 6, 2004
    Publication date: May 24, 2007
    Inventors: Louis Casteilla, Jean-Sebastien Silvestre, Valerie Planat-Benard, Bernard Levy, Luc Penicaud, Alain Tedgui
  • Publication number: 20060233799
    Abstract: The invention relates to the use of an inhibitor of IL-18 in the preparation of a medicament for treatment and/or prevention of peripheral vascular diseases. The invention further relates to the use of an IL-18 inhibitor for prevention of limb amputation.
    Type: Application
    Filed: March 13, 2003
    Publication date: October 19, 2006
    Inventors: Yolande Chvatchko, Alain Tedgui, Ziad Mallat
  • Publication number: 20040076628
    Abstract: The invention relates to the use of an IL-18 inhibitor for the manufacture of a medicament for the treatment and/or prevention of atherosclerosis.
    Type: Application
    Filed: February 25, 2003
    Publication date: April 22, 2004
    Inventors: Yolande Chvatchko, Alain Tedgui, Ziad Mallat