Patents by Inventor Alan L. Huston
Alan L. Huston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11767259Abstract: A copper-doped glass formed by placing a target glass in a container, surrounding the target glass with a powder mixture comprised of SiO2 powder and Cu2S powder, wherein the SiO2 powder and the Cu2S powder are mixed according to the formula (SiO2)(1-x)(Cu2S)x, where 0.01<x<0.1, and heated to a temperature of between 800° C. and 1150° C. for a duration of between 1 and 10 hours.Type: GrantFiled: December 10, 2020Date of Patent: September 26, 2023Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Barbara A. Marcheschi
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Patent number: 11287430Abstract: A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Emission correlates with cellular membrane potential.Type: GrantFiled: June 8, 2020Date of Patent: March 29, 2022Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: James B. Delehanty, Michael H. Stewart, Okhil Nag, Jeffrey R. Deschamps, Kimihiro Susumu, Eunkeu Oh, Lauren D. Field, Alexander L. Efros, Alan L. Huston, Igor L. Medintz, Philip E. Dawson
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Patent number: 11029428Abstract: Compositions including additive manufacturing materials incorporating radiological detection materials therein are provided. Also provided are apparatus and methods, which may be utilized to monitor and measure nuclear criticality events, and determine if personnel have been exposed to ionizing radiation. The compositions, apparatus, and methods beneficially improve accuracy in assessing radiation exposure, particularly neutron exposure, and reduce degradation of the radiological detection materials.Type: GrantFiled: May 6, 2019Date of Patent: June 8, 2021Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Luis A. Benevides, Alan L. Huston, Brian L. Justus, Barbara A. Marcheschi
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Patent number: 11028016Abstract: A method of making a copper-doped glass comprising placing a target glass in a container, placing a target glass in a container, surrounding the target glass with a powder mixture comprised of fused silica (SiO2) powder and copper sulfide (Cu2S) powder, such that both the target glass and the surrounding powder are contained in the container, and heating the container and the target glass and the surrounding powder mixture to a temperature of between 800° C. and 1150° C.Type: GrantFiled: October 10, 2018Date of Patent: June 8, 2021Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Barbara A. Marcheschi
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Publication number: 20210094872Abstract: A copper-doped glass formed by placing a target glass in a container, surrounding the target glass with a powder mixture comprised of SiO2 powder and Cu2S powder, wherein the SiO2 powder and the Cu2S powder are mixed according to the formula (SiO2)(1-x)(Cu2S)x, where 0.01<x<0.1, and heated to a temperature of between 800° C. and 1150° C. for a duration of between 1 and 10 hours.Type: ApplicationFiled: December 10, 2020Publication date: April 1, 2021Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Barbara A. Marcheschi
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Publication number: 20200355696Abstract: A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Emission correlates with cellular membrane potential.Type: ApplicationFiled: June 8, 2020Publication date: November 12, 2020Inventors: James B. Delehanty, Michael H. Stewart, Okhil Nag, Jeffrey R. Deschamps, Kimihiro Susumu, Eunkeu Oh, Lauren D. Field, Alexander L. Efros, Alan L. Huston, Igor L. Medintz, Philip E. Dawson
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Patent number: 10780185Abstract: A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Photoacoustic emission from the construct correlates with cellular membrane potential.Type: GrantFiled: July 10, 2018Date of Patent: September 22, 2020Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: James B. Delehanty, Michael H. Stewart, Okhil Nag, Jeffrey R. Deschamps, Kimihiro Susumu, Eunkeu Oh, Lauren D. Field, Alexander L. Efros, Alan L. Huston, Igor L. Medintz, Philip E. Dawson, Nashaat Rasheed, Parag V. Chitnis, John R. Cressman
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Patent number: 10705092Abstract: A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Emission correlates with cellular membrane potential.Type: GrantFiled: January 29, 2018Date of Patent: July 7, 2020Assignee: The Government of the United States of Americam as Represented by the Secretary of the NavyInventors: James B. Delehanty, Michael H. Stewart, Okhil Nag, Jeffrey R. Deschamps, Kimihiro Susumu, Eunkeu Oh, Lauren D. Field, Alexander L. Efros, Alan L. Huston, Igor L. Medintz, Philip E. Dawson
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Patent number: 10247848Abstract: A 3Helium gas counter comprising a container, a gas tube within the container, and a mixture of 3Helium and Xenon or a mixture of 3Helium and Krypton. A method of making a 3Helium gas counter comprising providing a container, placing a gas tube within the container, and depositing a mixture of 3Helium and Xenon or a mixture of 3Helium and Krypton into the gas tube.Type: GrantFiled: October 2, 2017Date of Patent: April 2, 2019Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Alan L. Justus
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Publication number: 20190039948Abstract: A method of making a copper-doped glass comprising placing a target glass in a container, placing a target glass in a container, surrounding the target glass with a powder mixture comprised of fused silica (SiO2) powder and copper sulfide (Cu2S) powder, such that both the target glass and the surrounding powder are contained in the container, and heating the container and the target glass and the surrounding powder mixture to a temperature of between 800° C. and 1150° C.Type: ApplicationFiled: October 10, 2018Publication date: February 7, 2019Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Barbara A. Marcheschi
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Publication number: 20180326097Abstract: A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Photoacoustic emission from the construct correlates with cellular membrane potential.Type: ApplicationFiled: July 10, 2018Publication date: November 15, 2018Inventors: James B. Delehanty, Michael H. Stewart, Okhil Nag, Jeffrey R. Deschamps, Kimihiro Susumu, Eunkeu Oh, Lauren D. Field, Alexander L. Efros, Alan L. Huston, Igor L. Medintz, Philip E. Dawson, Nashaat Rasheed, Parag V. Chitnis, John R. Cressman
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Patent number: 10125048Abstract: A copper dopant delivery powder comprising a fused silica powder and a Cu2S powder. A method of making the copper dopant delivery powder. A method of making a copper-doped glass comprising placing a target glass in a container, packing a composite SiO.CuS dopant powder around the target glass and heating the container and SiO.CuS dopant powder to a temperature of between 800° C. and 1150° C. A copper-doped glass comprising a glass comprising copper-doping wherein the copper-doped glass was formed by covering the glass with a fused silica powder and a Cu2S powder, wherein the fused silica powder and the Cu2S powder are mixed in varying ratios of Cu2S to silica represented by the formula (SiO2)(1-x)(Cu2S)x and heating to a temperature of between 800° C. and 1150° C.Type: GrantFiled: February 14, 2017Date of Patent: November 13, 2018Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Barbara A. Marcheschi
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Publication number: 20180217153Abstract: A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Emission correlates with cellular membrane potential.Type: ApplicationFiled: January 29, 2018Publication date: August 2, 2018Inventors: James B. Delehanty, Michael H. Stewart, Okhil Nag, Jeffrey R. Deschamps, Kimihiro Susumu, Eunkeu Oh, Lauren D. Field, Alexander L. Efros, Alan L. Huston, Igor L. Medintz, Philip E. Dawson
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Publication number: 20180045848Abstract: A 3Helium gas counter comprising a container, a gas tube within the container, and a mixture of 3Helium and Xenon or a mixture of 3Helium and Krypton. A method of making a 3Helium gas counter comprising providing a container, placing a gas tube within the container, and depositing a mixture of 3Helium and Xenon or a mixture of 3Helium and Krypton into the gas tube.Type: ApplicationFiled: October 2, 2017Publication date: February 15, 2018Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Alan L. Justus
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Patent number: 9880149Abstract: A glass pipette such as an electrode for electrophysiological recording is coated with quantum dots. This greatly aids the ability to observe the glass pipette, particular in tissue as the quantum dots provide an excellent performance under two-photon illumination used to visualize objects at depths of hundreds of microns.Type: GrantFiled: February 5, 2014Date of Patent: January 30, 2018Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Igor L. Medintz, Bertalan K. Andrasfalvy, Kimihiro Susumu, James B. Delehanty, Alan L. Huston, John J. Macklin, Mladen Barbic
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Patent number: 9778392Abstract: A 3Helium gas counter comprising polyethylene slabs, a rectangular gas tube within the polyethylene slabs, and a mixture of 3Helium and Xenon. A 3Helium gas counter comprising polyethylene slabs, a rectangular gas tube within the polyethylene slabs, and a mixture of 3Helium and Krypton. A method of making a 3Helium gas counter comprising providing polyethylene slabs, placing a rectangular gas tube within the polyethylene slabs, and depositing a mixture of 3Helium and Xenon into the rectangular gas tube.Type: GrantFiled: January 8, 2016Date of Patent: October 3, 2017Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Alan L. Justus
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Patent number: 9752986Abstract: Described herein is a time-gated, two-step FRET relay effective to provide temporal transference of a prompt FRET pathway, or provide spectro-temporal encoding analytical signals and other information. A FRET relay assembly includes a long lifetime FRET donor (for example, a lanthanide complex), a semiconductor quantum dot (QD) configured as an intermediate acceptor/donor in FRET, and a fluorescent dye configured as a terminal FRET acceptor, wherein the long lifetime FRET donor has an excited state lifetime of at least one microsecond and the QD and fluorescent dye each have excited state lifetimes of less than 100 nanoseconds.Type: GrantFiled: June 6, 2013Date of Patent: September 5, 2017Assignee: The United States of America, as represented by the Secretary of the NavyInventors: W. Russ Algar, Niko Hildebrandt, Alan L. Huston, Igor L. Medintz
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Publication number: 20170240457Abstract: A copper dopant delivery powder comprising a fused silica powder and a Cu2S powder. A method of making the copper dopant delivery powder. A method of making a copper-doped glass comprising placing a target glass in a container, packing a composite SiO.CuS dopant powder around the target glass and heating the container and SiO.CuS dopant powder to a temperature of between 800° C. and 1150° C. A copper-doped glass comprising a glass comprising copper-doping wherein the copper-doped glass was formed by covering the glass with a fused silica powder and a Cu2S powder, wherein the fused silica powder and the Cu2S powder are mixed in varying ratios of Cu2S to silica represented by the formula (SiO2)(1-x)(Cu2S)x and heating to a temperature of between 800° C. and 1150° C.Type: ApplicationFiled: February 14, 2017Publication date: August 24, 2017Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Barbara A. Marcheschi
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Patent number: 9720112Abstract: A device having: a scintillator material, an optically transparent element containing a glass or polymer and gadolinium oxide, and one or more photomultiplier tubes adjacent to the scintillator material. The optically transparent element is surrounded by the scintillator material.Type: GrantFiled: December 4, 2015Date of Patent: August 1, 2017Assignee: The Government of the United States of America as represented by the Secretary of the NavyInventors: Alan L. Huston, Brian L. Justus, Alan L. Justus
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Publication number: 20160216399Abstract: A 3Helium gas counter comprising polyethylene slabs, a rectangular gas tube within the polyethylene slabs, and a mixture of 3Helium and Xenon. A 3Helium gas counter comprising polyethylene slabs, a rectangular gas tube within the polyethylene slabs, and a mixture of 3Helium and Krypton. A method of making a 3Helium gas counter comprising providing polyethylene slabs, placing a rectangular gas tube within the polyethylene slabs, and depositing a mixture of 3Helium and Xenon into the rectangular gas tube.Type: ApplicationFiled: January 8, 2016Publication date: July 28, 2016Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Brian L. Justus, Alan L. Huston, Alan L. Justus