Abstract: A process for controlling the crystallization of certain hydrophobic active pharmaceutical ingredients (APIs) from a supercooled liquid state by hot-melt extrusion processing is described. Also described is a pharmaceutical composition comprising a solid crystalline dispersion of a cholesterol ester transfer protein inhibitor in a hydrophilic excipient matrix. In the process of the present invention, the API is fed to an extrusion system in a crystalline state contemporaneously with carrier excipients where it is first converted to a non-crystalline state by the application of heat and then subsequently recrystallized in-situ by the removal of heat and application of shear. Recrystallization of the API is controlled by carrier formulation design and the hot-melt extrusion process parameters; i.e. barrel temperature profile, feed rate, etc.

Abstract: A recycling container with a weather-resistant coating is described. The container may be provided in a variety of configurations to accept recyclable waste or other items of trash or refuse. The recycling container may itself be recycled when its useful life has ended. The various configurations of container may be combined to form a modular recycling center as desired by the user.

Abstract: Disclosed is a method of assembling three-dimensional display apparatus, comprising the steps of: providing a support unit comprising a projector mounting and a screen mounting surface with a first aperture therethrough; providing a screen unit, the screen unit comprising a diaphragm and an inflatable screen affixed thereto, the diaphragm defining a second aperture in communication with the interior of the inflatable screen; bringing the screen mounting surface and the diaphragm into contact so as to align the first aperture with the second aperture; and securing the support unit to the screen unit to thereby create a seal between the support surface and the diaphragm around the first and second apertures, wherein the seal is sufficiently gas tight to enable inflation of the screen.

Abstract: Field removable bonnet assemblies for use with valves are disclosed. An example internal valve includes an internal valve body and a field removable bonnet assembly. The field removable bonnet assembly includes a body that is to be removably coupled to the internal valve body and a shaft to be at least partially positioned within the body. The field removable bonnet assembly also includes an adjuster including a first adjuster portion and a second adjuster portion. The body defines a bore having a first diameter portion and a second diameter portion larger than the first diameter portion. The first diameter portion is to receive a valve packing. The second diameter portion to be threadably engaged by the second adjuster portion. The adjuster is externally accessible to adjust the first adjuster portion within the first diameter portion to change a force exerted by the valve packing on the shaft.

Abstract: A railroad well car includes a spaced trucks grouped in pairs, and a railcar body supported on a pair of the trucks, the body comprising a pair of spaced end structures, each end structure supported on one truck, and a well structure extending between the end structures. The well structure comprises a pair of top chord members extending between the end structures; a pair of side sills extending between the end structures; a pair of end chords extending between the side sills; four corner container support members, each secured to one end chord and one side sill; a plurality of floor beams extending between the side sills forming at least a portion of a floor for the well structure; and a plurality of side truss members extending between one side sill and one top chord on each side forming an open truss side for the well structure.

Abstract: The present invention relates to a granular pharmaceutical composition comprising an HCV protease inhibitor and at least one poloxamer.

Abstract: Field removable bonnet assemblies for use with valves are described herein. An example field removable bonnet assembly for use with internal valves includes a body that is to be removably coupled to the internal valve. The body defines a bore that is to receive a valve packing. Additionally, the field removable bonnet assembly includes a shaft having a cam assembly that is to rotatably engage a stem of the internal valve. The shaft is rotatably coupled to the body and the shaft is at least partially positioned within the bore. Further, the field removable bonnet assembly includes a removable adjuster that is externally accessible to enable an adjustment of the removable adjuster relative to the body to change a force exerted by the valve packing on the shaft. The removable adjuster is field removable to replace or repair the valve packing.

Abstract: A fluid handling and cogeneration system has an inlet conduit receiving a fluid, a housing having a inlet end, a outlet end and an interior surface. The housing encloses an inner body which together with the housing is arranged to form an annular space between the interior surface of the housing and an exterior surface of the inner body. The system also includes at least one diverter configured such that the fluid is directed to circulate around the inner body and traverse the annular space from the diverter toward the outlet end of the housing in an organized fashion. A generator is provided within the housing to harness the fluid traversing the annular space to generate electrical power.

Abstract: A fluid handling and cogeneration system has an inlet conduit receiving a fluid, a housing having a inlet end, a outlet end and an interior surface. The housing encloses an inner body which together with the housing is arranged to form an annular space between the interior surface of the housing and an exterior surface of the inner body. The system also includes at least one diverter configured such that the fluid is directed to circulate around the inner body and traverse the annular space from the diverter toward the outlet end of the housing in an organized fashion. A generator is provided within the housing to harness the fluid traversing the annular space to generate electrical power.

Abstract: A surface antenna for mobile use has a flat fiberglass base having a thickness of between 7.62 mm (0.300 in) and 12.70 mm (0.50 in), and at least one radiator on the base. The base is coated with a metal on its face lying the face carrying the antenna radiator. This coating forms a ground plane for the surface antenna, so that it can easily be used at the installation site in or on the mobile object.

Abstract: A railroad well car includes a pair of spaced trucks, and a railcar body supported on the trucks, the body comprising a pair of spaced end structures, each end structure supported on one truck, and a well structure extending between the end structures. The well structure comprises a pair of top chord members extending between the end structures; a pair of side sills extending between the end structures; a pair of end chords extending between the side sills; four corner container support members, each secured to one end chord and one side sill at four corners of the well structure; a plurality of floor beams extending between the side sills forming at least a portion of a floor for the well structure; and a plurality of side truss members extending between one side sill and one top chord on each side forming an open truss side for the well structure.

Abstract: A method and apparatus for combining micro-operations to process immediate data. The immediate data may be wider than the immediate data storage capacity of a micro-operation. A first micro-operation is issued to process a first portion of the immediate data, which can be processed within the immediate data storage capacity of a micro-operation. A second micro-operation is issued to process a second portion of the immediate data, which can be processed within the immediate data storage capacity of a micro-operation. Execution of the first and second micro-operations and optionally of a third micro-operation serves to reconstruct the immediate data comprising the first portion and the second portion of the immediate data.

Abstract: The present subject matter relates to operation frame filtering, building, and execution. Some embodiments include identifying a frame signature, counting a number of execution occurrences of the frame signature, and building a frame of operations to execute instead of operations identified by the frame signature.

Abstract: A service system receives a request for problem resolution knowledge from a service requestor. Upon receiving the request, the service system identifies candidate patterns where each candidate pattern has at least one element that characterizes a problem associated with the corresponding pattern. An iterative process is then repeated between the service requestor and the service system until a stopping criterion is met, which attempts to narrow the field of candidate patterns down until one or more possible root causes of the problem experienced by the service requestor are identified. Alternatively, it may be determined that a possible root cause of the problem is not contained in the candidate patterns or that some other action, event, etc., interrupts the iterative process.

Abstract: Redundant metal-to-metal seals for use with internal valves are described. A plug having redundant sealing functionality for use with a poppet of an internal valve includes a tapered surface to sealingly engage a seat of the poppet. Additionally, the plug includes a seal adjacent the tapered surface and disposed in a groove defined by the plug to sealingly engage the seat.

Abstract: A fluid handling and cogeneration system has an inlet conduit receiving a fluid, a housing having a inlet end, a outlet end and an interior surface. The housing encloses an inner body which together with the housing is arranged to form an annular space between the interior surface of the housing and an exterior surface of the inner body. The system also includes at least one diverter configured such that the fluid is directed to circulate around the inner body and traverse the annular space from the diverter toward the outlet end of the housing in an organized fashion. A generator is provided within the housing to harness the fluid traversing the annular space to generate electrical power.

Abstract: Field removable bonnet assemblies for use with valves are described herein. An example field removable bonnet assembly for use with internal valves includes a body that is to be removably coupled to the internal valve. The body defines a bore that is to receive a valve packing. Additionally, the field removable bonnet assembly includes a shaft having a cam assembly that is to rotatably engage a stem of the internal valve. The shaft is rotatably coupled to the body and the shaft is at least partially positioned within the bore. Further, the field removable bonnet assembly includes a removable adjuster that is externally accessible to enable an adjustment of the removable adjuster relative to the body to change a force exerted by the valve packing on the shaft. The removable adjuster is field removable to replace or repair the valve packing.

Abstract: Fluid flow control members for use with valves are described herein. An example fluid flow control member for use with a valve includes a body having a first seating surface to control a flow of fluid through the valve. The body defines a second seating surface opposite the first seating surface to control a flow of fluid through the valve. Additionally, the body defines an aperture to receive a stem of the valve, and a bore surrounded by the first seating surface to receive at least one of a seal or a sliding member each of which have a first surface to be engaged by a second surface of a spring seat coupled to the stem to control a fluid flow through the valve.

Abstract: Fluid flow control members for use with valves are described. An example poppet apparatus for use with an internal valve includes first and second opposing seating surfaces to control fluid flow through the internal valve. Additionally, the example poppet apparatus includes an aperture to receive a stem of the internal valve. Further, the example poppet apparatus includes a flow diverter to divert fluid flow through the poppet apparatus to substantially prevent the fluid flow from compressing a spring to be at least partially positioned in the poppet apparatus.